Genetic influence alters the brain synchronism in perception and timing
Abstract Background Studies at the molecular level aim to integrate genetic and neurobiological data to provide an increasingly detailed understanding of phenotypes related to the ability in time perception. Main Text This study suggests that the polymorphisms genetic SLC6A4 5-HTTLPR, 5HTR2A T102C,...
Ausführliche Beschreibung
Autor*in: |
Victor Marinho [verfasserIn] Thomaz Oliveira [verfasserIn] Juliete Bandeira [verfasserIn] Giovanny R. Pinto [verfasserIn] Anderson Gomes [verfasserIn] Valéria Lima [verfasserIn] Francisco Magalhães [verfasserIn] Kaline Rocha [verfasserIn] Carla Ayres [verfasserIn] Valécia Carvalho [verfasserIn] Bruna Velasques [verfasserIn] Pedro Ribeiro [verfasserIn] Marco Orsini [verfasserIn] Victor Hugo Bastos [verfasserIn] Daya Gupta [verfasserIn] Silmar Teixeira [verfasserIn] |
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E-Artikel |
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Sprache: |
Englisch |
Erschienen: |
2018 |
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In: Journal of Biomedical Science - BMC, 2002, 25(2018), 1, Seite 11 |
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Übergeordnetes Werk: |
volume:25 ; year:2018 ; number:1 ; pages:11 |
Links: |
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DOI / URN: |
10.1186/s12929-018-0463-z |
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Katalog-ID: |
DOAJ013164449 |
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520 | |a Abstract Background Studies at the molecular level aim to integrate genetic and neurobiological data to provide an increasingly detailed understanding of phenotypes related to the ability in time perception. Main Text This study suggests that the polymorphisms genetic SLC6A4 5-HTTLPR, 5HTR2A T102C, DRD2/ANKK1-Taq1A, SLC6A3 3’-UTR VNTR, COMT Val158Met, CLOCK genes and GABRB2 A/C as modification factor at neurochemical levels associated with several neurofunctional aspects, modifying the circadian rhythm and built-in cognitive functions in the timing. We conducted a literature review with 102 studies that met inclusion criteria to synthesize findings on genetic polymorphisms and their influence on the timing. Conclusion The findings suggest an association of genetic polymorphisms on behavioral aspects related in timing. However, order to confirm the paradigm of association in the timing as a function of the molecular level, still need to be addressed future research. | ||
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10.1186/s12929-018-0463-z doi (DE-627)DOAJ013164449 (DE-599)DOAJ5cb8632d4c514efcb92cd6b3e7838652 DE-627 ger DE-627 rakwb eng Victor Marinho verfasserin aut Genetic influence alters the brain synchronism in perception and timing 2018 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract Background Studies at the molecular level aim to integrate genetic and neurobiological data to provide an increasingly detailed understanding of phenotypes related to the ability in time perception. Main Text This study suggests that the polymorphisms genetic SLC6A4 5-HTTLPR, 5HTR2A T102C, DRD2/ANKK1-Taq1A, SLC6A3 3’-UTR VNTR, COMT Val158Met, CLOCK genes and GABRB2 A/C as modification factor at neurochemical levels associated with several neurofunctional aspects, modifying the circadian rhythm and built-in cognitive functions in the timing. We conducted a literature review with 102 studies that met inclusion criteria to synthesize findings on genetic polymorphisms and their influence on the timing. Conclusion The findings suggest an association of genetic polymorphisms on behavioral aspects related in timing. However, order to confirm the paradigm of association in the timing as a function of the molecular level, still need to be addressed future research. Time perception Genetic polymorphisms Serotonin Dopamine Circadian rhythm GABA Medicine R Thomaz Oliveira verfasserin aut Juliete Bandeira verfasserin aut Giovanny R. Pinto verfasserin aut Anderson Gomes verfasserin aut Valéria Lima verfasserin aut Francisco Magalhães verfasserin aut Kaline Rocha verfasserin aut Carla Ayres verfasserin aut Valécia Carvalho verfasserin aut Bruna Velasques verfasserin aut Pedro Ribeiro verfasserin aut Marco Orsini verfasserin aut Victor Hugo Bastos verfasserin aut Daya Gupta verfasserin aut Silmar Teixeira verfasserin aut In Journal of Biomedical Science BMC, 2002 25(2018), 1, Seite 11 (DE-627)300593724 (DE-600)1482918-6 14230127 nnns volume:25 year:2018 number:1 pages:11 https://doi.org/10.1186/s12929-018-0463-z kostenfrei https://doaj.org/article/5cb8632d4c514efcb92cd6b3e7838652 kostenfrei http://link.springer.com/article/10.1186/s12929-018-0463-z kostenfrei https://doaj.org/toc/1423-0127 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2061 GBV_ILN_2111 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4328 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 25 2018 1 11 |
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10.1186/s12929-018-0463-z doi (DE-627)DOAJ013164449 (DE-599)DOAJ5cb8632d4c514efcb92cd6b3e7838652 DE-627 ger DE-627 rakwb eng Victor Marinho verfasserin aut Genetic influence alters the brain synchronism in perception and timing 2018 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract Background Studies at the molecular level aim to integrate genetic and neurobiological data to provide an increasingly detailed understanding of phenotypes related to the ability in time perception. Main Text This study suggests that the polymorphisms genetic SLC6A4 5-HTTLPR, 5HTR2A T102C, DRD2/ANKK1-Taq1A, SLC6A3 3’-UTR VNTR, COMT Val158Met, CLOCK genes and GABRB2 A/C as modification factor at neurochemical levels associated with several neurofunctional aspects, modifying the circadian rhythm and built-in cognitive functions in the timing. We conducted a literature review with 102 studies that met inclusion criteria to synthesize findings on genetic polymorphisms and their influence on the timing. Conclusion The findings suggest an association of genetic polymorphisms on behavioral aspects related in timing. However, order to confirm the paradigm of association in the timing as a function of the molecular level, still need to be addressed future research. Time perception Genetic polymorphisms Serotonin Dopamine Circadian rhythm GABA Medicine R Thomaz Oliveira verfasserin aut Juliete Bandeira verfasserin aut Giovanny R. Pinto verfasserin aut Anderson Gomes verfasserin aut Valéria Lima verfasserin aut Francisco Magalhães verfasserin aut Kaline Rocha verfasserin aut Carla Ayres verfasserin aut Valécia Carvalho verfasserin aut Bruna Velasques verfasserin aut Pedro Ribeiro verfasserin aut Marco Orsini verfasserin aut Victor Hugo Bastos verfasserin aut Daya Gupta verfasserin aut Silmar Teixeira verfasserin aut In Journal of Biomedical Science BMC, 2002 25(2018), 1, Seite 11 (DE-627)300593724 (DE-600)1482918-6 14230127 nnns volume:25 year:2018 number:1 pages:11 https://doi.org/10.1186/s12929-018-0463-z kostenfrei https://doaj.org/article/5cb8632d4c514efcb92cd6b3e7838652 kostenfrei http://link.springer.com/article/10.1186/s12929-018-0463-z kostenfrei https://doaj.org/toc/1423-0127 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2061 GBV_ILN_2111 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4328 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 25 2018 1 11 |
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10.1186/s12929-018-0463-z doi (DE-627)DOAJ013164449 (DE-599)DOAJ5cb8632d4c514efcb92cd6b3e7838652 DE-627 ger DE-627 rakwb eng Victor Marinho verfasserin aut Genetic influence alters the brain synchronism in perception and timing 2018 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract Background Studies at the molecular level aim to integrate genetic and neurobiological data to provide an increasingly detailed understanding of phenotypes related to the ability in time perception. Main Text This study suggests that the polymorphisms genetic SLC6A4 5-HTTLPR, 5HTR2A T102C, DRD2/ANKK1-Taq1A, SLC6A3 3’-UTR VNTR, COMT Val158Met, CLOCK genes and GABRB2 A/C as modification factor at neurochemical levels associated with several neurofunctional aspects, modifying the circadian rhythm and built-in cognitive functions in the timing. We conducted a literature review with 102 studies that met inclusion criteria to synthesize findings on genetic polymorphisms and their influence on the timing. Conclusion The findings suggest an association of genetic polymorphisms on behavioral aspects related in timing. However, order to confirm the paradigm of association in the timing as a function of the molecular level, still need to be addressed future research. Time perception Genetic polymorphisms Serotonin Dopamine Circadian rhythm GABA Medicine R Thomaz Oliveira verfasserin aut Juliete Bandeira verfasserin aut Giovanny R. Pinto verfasserin aut Anderson Gomes verfasserin aut Valéria Lima verfasserin aut Francisco Magalhães verfasserin aut Kaline Rocha verfasserin aut Carla Ayres verfasserin aut Valécia Carvalho verfasserin aut Bruna Velasques verfasserin aut Pedro Ribeiro verfasserin aut Marco Orsini verfasserin aut Victor Hugo Bastos verfasserin aut Daya Gupta verfasserin aut Silmar Teixeira verfasserin aut In Journal of Biomedical Science BMC, 2002 25(2018), 1, Seite 11 (DE-627)300593724 (DE-600)1482918-6 14230127 nnns volume:25 year:2018 number:1 pages:11 https://doi.org/10.1186/s12929-018-0463-z kostenfrei https://doaj.org/article/5cb8632d4c514efcb92cd6b3e7838652 kostenfrei http://link.springer.com/article/10.1186/s12929-018-0463-z kostenfrei https://doaj.org/toc/1423-0127 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2061 GBV_ILN_2111 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4328 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 25 2018 1 11 |
allfieldsGer |
10.1186/s12929-018-0463-z doi (DE-627)DOAJ013164449 (DE-599)DOAJ5cb8632d4c514efcb92cd6b3e7838652 DE-627 ger DE-627 rakwb eng Victor Marinho verfasserin aut Genetic influence alters the brain synchronism in perception and timing 2018 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract Background Studies at the molecular level aim to integrate genetic and neurobiological data to provide an increasingly detailed understanding of phenotypes related to the ability in time perception. Main Text This study suggests that the polymorphisms genetic SLC6A4 5-HTTLPR, 5HTR2A T102C, DRD2/ANKK1-Taq1A, SLC6A3 3’-UTR VNTR, COMT Val158Met, CLOCK genes and GABRB2 A/C as modification factor at neurochemical levels associated with several neurofunctional aspects, modifying the circadian rhythm and built-in cognitive functions in the timing. We conducted a literature review with 102 studies that met inclusion criteria to synthesize findings on genetic polymorphisms and their influence on the timing. Conclusion The findings suggest an association of genetic polymorphisms on behavioral aspects related in timing. However, order to confirm the paradigm of association in the timing as a function of the molecular level, still need to be addressed future research. Time perception Genetic polymorphisms Serotonin Dopamine Circadian rhythm GABA Medicine R Thomaz Oliveira verfasserin aut Juliete Bandeira verfasserin aut Giovanny R. Pinto verfasserin aut Anderson Gomes verfasserin aut Valéria Lima verfasserin aut Francisco Magalhães verfasserin aut Kaline Rocha verfasserin aut Carla Ayres verfasserin aut Valécia Carvalho verfasserin aut Bruna Velasques verfasserin aut Pedro Ribeiro verfasserin aut Marco Orsini verfasserin aut Victor Hugo Bastos verfasserin aut Daya Gupta verfasserin aut Silmar Teixeira verfasserin aut In Journal of Biomedical Science BMC, 2002 25(2018), 1, Seite 11 (DE-627)300593724 (DE-600)1482918-6 14230127 nnns volume:25 year:2018 number:1 pages:11 https://doi.org/10.1186/s12929-018-0463-z kostenfrei https://doaj.org/article/5cb8632d4c514efcb92cd6b3e7838652 kostenfrei http://link.springer.com/article/10.1186/s12929-018-0463-z kostenfrei https://doaj.org/toc/1423-0127 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2061 GBV_ILN_2111 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4328 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 25 2018 1 11 |
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10.1186/s12929-018-0463-z doi (DE-627)DOAJ013164449 (DE-599)DOAJ5cb8632d4c514efcb92cd6b3e7838652 DE-627 ger DE-627 rakwb eng Victor Marinho verfasserin aut Genetic influence alters the brain synchronism in perception and timing 2018 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract Background Studies at the molecular level aim to integrate genetic and neurobiological data to provide an increasingly detailed understanding of phenotypes related to the ability in time perception. Main Text This study suggests that the polymorphisms genetic SLC6A4 5-HTTLPR, 5HTR2A T102C, DRD2/ANKK1-Taq1A, SLC6A3 3’-UTR VNTR, COMT Val158Met, CLOCK genes and GABRB2 A/C as modification factor at neurochemical levels associated with several neurofunctional aspects, modifying the circadian rhythm and built-in cognitive functions in the timing. We conducted a literature review with 102 studies that met inclusion criteria to synthesize findings on genetic polymorphisms and their influence on the timing. Conclusion The findings suggest an association of genetic polymorphisms on behavioral aspects related in timing. However, order to confirm the paradigm of association in the timing as a function of the molecular level, still need to be addressed future research. Time perception Genetic polymorphisms Serotonin Dopamine Circadian rhythm GABA Medicine R Thomaz Oliveira verfasserin aut Juliete Bandeira verfasserin aut Giovanny R. Pinto verfasserin aut Anderson Gomes verfasserin aut Valéria Lima verfasserin aut Francisco Magalhães verfasserin aut Kaline Rocha verfasserin aut Carla Ayres verfasserin aut Valécia Carvalho verfasserin aut Bruna Velasques verfasserin aut Pedro Ribeiro verfasserin aut Marco Orsini verfasserin aut Victor Hugo Bastos verfasserin aut Daya Gupta verfasserin aut Silmar Teixeira verfasserin aut In Journal of Biomedical Science BMC, 2002 25(2018), 1, Seite 11 (DE-627)300593724 (DE-600)1482918-6 14230127 nnns volume:25 year:2018 number:1 pages:11 https://doi.org/10.1186/s12929-018-0463-z kostenfrei https://doaj.org/article/5cb8632d4c514efcb92cd6b3e7838652 kostenfrei http://link.springer.com/article/10.1186/s12929-018-0463-z kostenfrei https://doaj.org/toc/1423-0127 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2027 GBV_ILN_2031 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2061 GBV_ILN_2111 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4328 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 25 2018 1 11 |
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Victor Marinho @@aut@@ Thomaz Oliveira @@aut@@ Juliete Bandeira @@aut@@ Giovanny R. Pinto @@aut@@ Anderson Gomes @@aut@@ Valéria Lima @@aut@@ Francisco Magalhães @@aut@@ Kaline Rocha @@aut@@ Carla Ayres @@aut@@ Valécia Carvalho @@aut@@ Bruna Velasques @@aut@@ Pedro Ribeiro @@aut@@ Marco Orsini @@aut@@ Victor Hugo Bastos @@aut@@ Daya Gupta @@aut@@ Silmar Teixeira @@aut@@ |
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Genetic influence alters the brain synchronism in perception and timing Time perception Genetic polymorphisms Serotonin Dopamine Circadian rhythm GABA |
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Victor Marinho Thomaz Oliveira Juliete Bandeira Giovanny R. Pinto Anderson Gomes Valéria Lima Francisco Magalhães Kaline Rocha Carla Ayres Valécia Carvalho Bruna Velasques Pedro Ribeiro Marco Orsini Victor Hugo Bastos Daya Gupta Silmar Teixeira |
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genetic influence alters the brain synchronism in perception and timing |
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Genetic influence alters the brain synchronism in perception and timing |
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Abstract Background Studies at the molecular level aim to integrate genetic and neurobiological data to provide an increasingly detailed understanding of phenotypes related to the ability in time perception. Main Text This study suggests that the polymorphisms genetic SLC6A4 5-HTTLPR, 5HTR2A T102C, DRD2/ANKK1-Taq1A, SLC6A3 3’-UTR VNTR, COMT Val158Met, CLOCK genes and GABRB2 A/C as modification factor at neurochemical levels associated with several neurofunctional aspects, modifying the circadian rhythm and built-in cognitive functions in the timing. We conducted a literature review with 102 studies that met inclusion criteria to synthesize findings on genetic polymorphisms and their influence on the timing. Conclusion The findings suggest an association of genetic polymorphisms on behavioral aspects related in timing. However, order to confirm the paradigm of association in the timing as a function of the molecular level, still need to be addressed future research. |
abstractGer |
Abstract Background Studies at the molecular level aim to integrate genetic and neurobiological data to provide an increasingly detailed understanding of phenotypes related to the ability in time perception. Main Text This study suggests that the polymorphisms genetic SLC6A4 5-HTTLPR, 5HTR2A T102C, DRD2/ANKK1-Taq1A, SLC6A3 3’-UTR VNTR, COMT Val158Met, CLOCK genes and GABRB2 A/C as modification factor at neurochemical levels associated with several neurofunctional aspects, modifying the circadian rhythm and built-in cognitive functions in the timing. We conducted a literature review with 102 studies that met inclusion criteria to synthesize findings on genetic polymorphisms and their influence on the timing. Conclusion The findings suggest an association of genetic polymorphisms on behavioral aspects related in timing. However, order to confirm the paradigm of association in the timing as a function of the molecular level, still need to be addressed future research. |
abstract_unstemmed |
Abstract Background Studies at the molecular level aim to integrate genetic and neurobiological data to provide an increasingly detailed understanding of phenotypes related to the ability in time perception. Main Text This study suggests that the polymorphisms genetic SLC6A4 5-HTTLPR, 5HTR2A T102C, DRD2/ANKK1-Taq1A, SLC6A3 3’-UTR VNTR, COMT Val158Met, CLOCK genes and GABRB2 A/C as modification factor at neurochemical levels associated with several neurofunctional aspects, modifying the circadian rhythm and built-in cognitive functions in the timing. We conducted a literature review with 102 studies that met inclusion criteria to synthesize findings on genetic polymorphisms and their influence on the timing. Conclusion The findings suggest an association of genetic polymorphisms on behavioral aspects related in timing. However, order to confirm the paradigm of association in the timing as a function of the molecular level, still need to be addressed future research. |
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Genetic influence alters the brain synchronism in perception and timing |
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Thomaz Oliveira Juliete Bandeira Giovanny R. Pinto Anderson Gomes Valéria Lima Francisco Magalhães Kaline Rocha Carla Ayres Valécia Carvalho Bruna Velasques Pedro Ribeiro Marco Orsini Victor Hugo Bastos Daya Gupta Silmar Teixeira |
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Thomaz Oliveira Juliete Bandeira Giovanny R. Pinto Anderson Gomes Valéria Lima Francisco Magalhães Kaline Rocha Carla Ayres Valécia Carvalho Bruna Velasques Pedro Ribeiro Marco Orsini Victor Hugo Bastos Daya Gupta Silmar Teixeira |
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