Megahertz pulse trains enable multi-hit serial femtosecond crystallography experiments at X-ray free electron lasers
Free-electron lasers are capable of high repetition rates and it is assumed that protein crystals often do not survive the first X-ray pulse. Here the authors address these issues with a demonstration of multi-hit serial crystallography in which multiple FEL pulses interact with the sample without d...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Susannah Holmes [verfasserIn] Henry J. Kirkwood [verfasserIn] Richard Bean [verfasserIn] Klaus Giewekemeyer [verfasserIn] Andrew V. Martin [verfasserIn] Marjan Hadian-Jazi [verfasserIn] Max O. Wiedorn [verfasserIn] Dominik Oberthür [verfasserIn] Hugh Marman [verfasserIn] Luigi Adriano [verfasserIn] Nasser Al-Qudami [verfasserIn] Saša Bajt [verfasserIn] Imrich Barák [verfasserIn] Sadia Bari [verfasserIn] Johan Bielecki [verfasserIn] Sandor Brockhauser [verfasserIn] Mathew A. Coleman [verfasserIn] Francisco Cruz-Mazo [verfasserIn] Cyril Danilevski [verfasserIn] Katerina Dörner [verfasserIn] Alfonso M. Gañán-Calvo [verfasserIn] Rita Graceffa [verfasserIn] Hans Fanghor [verfasserIn] Michael Heymann [verfasserIn] Matthias Frank [verfasserIn] Alexander Kaukher [verfasserIn] Yoonhee Kim [verfasserIn] Bostjan Kobe [verfasserIn] Juraj Knoška [verfasserIn] Torsten Laurus [verfasserIn] Romain Letrun [verfasserIn] Luis Maia [verfasserIn] Marc Messerschmidt [verfasserIn] Markus Metz [verfasserIn] Thomas Michelat [verfasserIn] Grant Mills [verfasserIn] Serguei Molodtsov [verfasserIn] Diana C. F. Monteiro [verfasserIn] Andrew J. Morgan [verfasserIn] Astrid Münnich [verfasserIn] Gisel E. Peña Murillo [verfasserIn] Gianpietro Previtali [verfasserIn] Adam Round [verfasserIn] Tokushi Sato [verfasserIn] Robin Schubert [verfasserIn] Joachim Schulz [verfasserIn] Megan Shelby [verfasserIn] Carolin Seuring [verfasserIn] Jonas A. Sellberg [verfasserIn] Marcin Sikorski [verfasserIn] Alessandro Silenzi [verfasserIn] Stephan Stern [verfasserIn] Jola Sztuk-Dambietz [verfasserIn] Janusz Szuba [verfasserIn] Martin Trebbin [verfasserIn] Patrick Vagovic [verfasserIn] Thomas Ve [verfasserIn] Britta Weinhausen [verfasserIn] Krzysztof Wrona [verfasserIn] Paul Lourdu Xavier [verfasserIn] Chen Xu [verfasserIn] Oleksandr Yefanov [verfasserIn] Keith A. Nugent [verfasserIn] Henry N. Chapman [verfasserIn] Adrian P. Mancuso [verfasserIn] Anton Barty [verfasserIn] Brian Abbey [verfasserIn] Connie Darmanin [verfasserIn] |
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| Format: |
E-Artikel |
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| Sprache: |
Englisch |
| Erschienen: |
2022 |
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| Übergeordnetes Werk: |
In: Nature Communications - Nature Portfolio, 2016, 13(2022), 1, Seite 13 |
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| Übergeordnetes Werk: |
volume:13 ; year:2022 ; number:1 ; pages:13 |
| Links: |
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| DOI / URN: |
10.1038/s41467-022-32434-6 |
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DOAJ015553744 |
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| 245 | 1 | 0 | |a Megahertz pulse trains enable multi-hit serial femtosecond crystallography experiments at X-ray free electron lasers |
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| 520 | |a Free-electron lasers are capable of high repetition rates and it is assumed that protein crystals often do not survive the first X-ray pulse. Here the authors address these issues with a demonstration of multi-hit serial crystallography in which multiple FEL pulses interact with the sample without destroying it. | ||
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10.1038/s41467-022-32434-6 doi (DE-627)DOAJ015553744 (DE-599)DOAJ2126addb96a243bbab803f29ff675139 DE-627 ger DE-627 rakwb eng Susannah Holmes verfasserin aut Megahertz pulse trains enable multi-hit serial femtosecond crystallography experiments at X-ray free electron lasers 2022 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Free-electron lasers are capable of high repetition rates and it is assumed that protein crystals often do not survive the first X-ray pulse. Here the authors address these issues with a demonstration of multi-hit serial crystallography in which multiple FEL pulses interact with the sample without destroying it. Science Q Henry J. Kirkwood verfasserin aut Richard Bean verfasserin aut Klaus Giewekemeyer verfasserin aut Andrew V. Martin verfasserin aut Marjan Hadian-Jazi verfasserin aut Max O. Wiedorn verfasserin aut Dominik Oberthür verfasserin aut Hugh Marman verfasserin aut Luigi Adriano verfasserin aut Nasser Al-Qudami verfasserin aut Saša Bajt verfasserin aut Imrich Barák verfasserin aut Sadia Bari verfasserin aut Johan Bielecki verfasserin aut Sandor Brockhauser verfasserin aut Mathew A. Coleman verfasserin aut Francisco Cruz-Mazo verfasserin aut Cyril Danilevski verfasserin aut Katerina Dörner verfasserin aut Alfonso M. Gañán-Calvo verfasserin aut Rita Graceffa verfasserin aut Hans Fanghor verfasserin aut Michael Heymann verfasserin aut Matthias Frank verfasserin aut Alexander Kaukher verfasserin aut Yoonhee Kim verfasserin aut Bostjan Kobe verfasserin aut Juraj Knoška verfasserin aut Torsten Laurus verfasserin aut Romain Letrun verfasserin aut Luis Maia verfasserin aut Marc Messerschmidt verfasserin aut Markus Metz verfasserin aut Thomas Michelat verfasserin aut Grant Mills verfasserin aut Serguei Molodtsov verfasserin aut Diana C. F. Monteiro verfasserin aut Andrew J. Morgan verfasserin aut Astrid Münnich verfasserin aut Gisel E. Peña Murillo verfasserin aut Gianpietro Previtali verfasserin aut Adam Round verfasserin aut Tokushi Sato verfasserin aut Robin Schubert verfasserin aut Joachim Schulz verfasserin aut Megan Shelby verfasserin aut Carolin Seuring verfasserin aut Jonas A. Sellberg verfasserin aut Marcin Sikorski verfasserin aut Alessandro Silenzi verfasserin aut Stephan Stern verfasserin aut Jola Sztuk-Dambietz verfasserin aut Janusz Szuba verfasserin aut Martin Trebbin verfasserin aut Patrick Vagovic verfasserin aut Thomas Ve verfasserin aut Britta Weinhausen verfasserin aut Krzysztof Wrona verfasserin aut Paul Lourdu Xavier verfasserin aut Chen Xu verfasserin aut Oleksandr Yefanov verfasserin aut Keith A. Nugent verfasserin aut Henry N. Chapman verfasserin aut Adrian P. Mancuso verfasserin aut Anton Barty verfasserin aut Brian Abbey verfasserin aut Connie Darmanin verfasserin aut In Nature Communications Nature Portfolio, 2016 13(2022), 1, Seite 13 (DE-627)626457688 (DE-600)2553671-0 20411723 nnns volume:13 year:2022 number:1 pages:13 https://doi.org/10.1038/s41467-022-32434-6 kostenfrei https://doaj.org/article/2126addb96a243bbab803f29ff675139 kostenfrei https://doi.org/10.1038/s41467-022-32434-6 kostenfrei https://doaj.org/toc/2041-1723 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_211 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_2110 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 13 2022 1 13 |
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10.1038/s41467-022-32434-6 doi (DE-627)DOAJ015553744 (DE-599)DOAJ2126addb96a243bbab803f29ff675139 DE-627 ger DE-627 rakwb eng Susannah Holmes verfasserin aut Megahertz pulse trains enable multi-hit serial femtosecond crystallography experiments at X-ray free electron lasers 2022 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Free-electron lasers are capable of high repetition rates and it is assumed that protein crystals often do not survive the first X-ray pulse. Here the authors address these issues with a demonstration of multi-hit serial crystallography in which multiple FEL pulses interact with the sample without destroying it. Science Q Henry J. Kirkwood verfasserin aut Richard Bean verfasserin aut Klaus Giewekemeyer verfasserin aut Andrew V. Martin verfasserin aut Marjan Hadian-Jazi verfasserin aut Max O. Wiedorn verfasserin aut Dominik Oberthür verfasserin aut Hugh Marman verfasserin aut Luigi Adriano verfasserin aut Nasser Al-Qudami verfasserin aut Saša Bajt verfasserin aut Imrich Barák verfasserin aut Sadia Bari verfasserin aut Johan Bielecki verfasserin aut Sandor Brockhauser verfasserin aut Mathew A. Coleman verfasserin aut Francisco Cruz-Mazo verfasserin aut Cyril Danilevski verfasserin aut Katerina Dörner verfasserin aut Alfonso M. Gañán-Calvo verfasserin aut Rita Graceffa verfasserin aut Hans Fanghor verfasserin aut Michael Heymann verfasserin aut Matthias Frank verfasserin aut Alexander Kaukher verfasserin aut Yoonhee Kim verfasserin aut Bostjan Kobe verfasserin aut Juraj Knoška verfasserin aut Torsten Laurus verfasserin aut Romain Letrun verfasserin aut Luis Maia verfasserin aut Marc Messerschmidt verfasserin aut Markus Metz verfasserin aut Thomas Michelat verfasserin aut Grant Mills verfasserin aut Serguei Molodtsov verfasserin aut Diana C. F. Monteiro verfasserin aut Andrew J. Morgan verfasserin aut Astrid Münnich verfasserin aut Gisel E. Peña Murillo verfasserin aut Gianpietro Previtali verfasserin aut Adam Round verfasserin aut Tokushi Sato verfasserin aut Robin Schubert verfasserin aut Joachim Schulz verfasserin aut Megan Shelby verfasserin aut Carolin Seuring verfasserin aut Jonas A. Sellberg verfasserin aut Marcin Sikorski verfasserin aut Alessandro Silenzi verfasserin aut Stephan Stern verfasserin aut Jola Sztuk-Dambietz verfasserin aut Janusz Szuba verfasserin aut Martin Trebbin verfasserin aut Patrick Vagovic verfasserin aut Thomas Ve verfasserin aut Britta Weinhausen verfasserin aut Krzysztof Wrona verfasserin aut Paul Lourdu Xavier verfasserin aut Chen Xu verfasserin aut Oleksandr Yefanov verfasserin aut Keith A. Nugent verfasserin aut Henry N. Chapman verfasserin aut Adrian P. Mancuso verfasserin aut Anton Barty verfasserin aut Brian Abbey verfasserin aut Connie Darmanin verfasserin aut In Nature Communications Nature Portfolio, 2016 13(2022), 1, Seite 13 (DE-627)626457688 (DE-600)2553671-0 20411723 nnns volume:13 year:2022 number:1 pages:13 https://doi.org/10.1038/s41467-022-32434-6 kostenfrei https://doaj.org/article/2126addb96a243bbab803f29ff675139 kostenfrei https://doi.org/10.1038/s41467-022-32434-6 kostenfrei https://doaj.org/toc/2041-1723 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_211 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_2110 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 13 2022 1 13 |
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10.1038/s41467-022-32434-6 doi (DE-627)DOAJ015553744 (DE-599)DOAJ2126addb96a243bbab803f29ff675139 DE-627 ger DE-627 rakwb eng Susannah Holmes verfasserin aut Megahertz pulse trains enable multi-hit serial femtosecond crystallography experiments at X-ray free electron lasers 2022 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Free-electron lasers are capable of high repetition rates and it is assumed that protein crystals often do not survive the first X-ray pulse. Here the authors address these issues with a demonstration of multi-hit serial crystallography in which multiple FEL pulses interact with the sample without destroying it. Science Q Henry J. Kirkwood verfasserin aut Richard Bean verfasserin aut Klaus Giewekemeyer verfasserin aut Andrew V. Martin verfasserin aut Marjan Hadian-Jazi verfasserin aut Max O. Wiedorn verfasserin aut Dominik Oberthür verfasserin aut Hugh Marman verfasserin aut Luigi Adriano verfasserin aut Nasser Al-Qudami verfasserin aut Saša Bajt verfasserin aut Imrich Barák verfasserin aut Sadia Bari verfasserin aut Johan Bielecki verfasserin aut Sandor Brockhauser verfasserin aut Mathew A. Coleman verfasserin aut Francisco Cruz-Mazo verfasserin aut Cyril Danilevski verfasserin aut Katerina Dörner verfasserin aut Alfonso M. Gañán-Calvo verfasserin aut Rita Graceffa verfasserin aut Hans Fanghor verfasserin aut Michael Heymann verfasserin aut Matthias Frank verfasserin aut Alexander Kaukher verfasserin aut Yoonhee Kim verfasserin aut Bostjan Kobe verfasserin aut Juraj Knoška verfasserin aut Torsten Laurus verfasserin aut Romain Letrun verfasserin aut Luis Maia verfasserin aut Marc Messerschmidt verfasserin aut Markus Metz verfasserin aut Thomas Michelat verfasserin aut Grant Mills verfasserin aut Serguei Molodtsov verfasserin aut Diana C. F. Monteiro verfasserin aut Andrew J. Morgan verfasserin aut Astrid Münnich verfasserin aut Gisel E. Peña Murillo verfasserin aut Gianpietro Previtali verfasserin aut Adam Round verfasserin aut Tokushi Sato verfasserin aut Robin Schubert verfasserin aut Joachim Schulz verfasserin aut Megan Shelby verfasserin aut Carolin Seuring verfasserin aut Jonas A. Sellberg verfasserin aut Marcin Sikorski verfasserin aut Alessandro Silenzi verfasserin aut Stephan Stern verfasserin aut Jola Sztuk-Dambietz verfasserin aut Janusz Szuba verfasserin aut Martin Trebbin verfasserin aut Patrick Vagovic verfasserin aut Thomas Ve verfasserin aut Britta Weinhausen verfasserin aut Krzysztof Wrona verfasserin aut Paul Lourdu Xavier verfasserin aut Chen Xu verfasserin aut Oleksandr Yefanov verfasserin aut Keith A. Nugent verfasserin aut Henry N. Chapman verfasserin aut Adrian P. Mancuso verfasserin aut Anton Barty verfasserin aut Brian Abbey verfasserin aut Connie Darmanin verfasserin aut In Nature Communications Nature Portfolio, 2016 13(2022), 1, Seite 13 (DE-627)626457688 (DE-600)2553671-0 20411723 nnns volume:13 year:2022 number:1 pages:13 https://doi.org/10.1038/s41467-022-32434-6 kostenfrei https://doaj.org/article/2126addb96a243bbab803f29ff675139 kostenfrei https://doi.org/10.1038/s41467-022-32434-6 kostenfrei https://doaj.org/toc/2041-1723 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_211 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_2110 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 13 2022 1 13 |
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10.1038/s41467-022-32434-6 doi (DE-627)DOAJ015553744 (DE-599)DOAJ2126addb96a243bbab803f29ff675139 DE-627 ger DE-627 rakwb eng Susannah Holmes verfasserin aut Megahertz pulse trains enable multi-hit serial femtosecond crystallography experiments at X-ray free electron lasers 2022 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Free-electron lasers are capable of high repetition rates and it is assumed that protein crystals often do not survive the first X-ray pulse. Here the authors address these issues with a demonstration of multi-hit serial crystallography in which multiple FEL pulses interact with the sample without destroying it. Science Q Henry J. Kirkwood verfasserin aut Richard Bean verfasserin aut Klaus Giewekemeyer verfasserin aut Andrew V. Martin verfasserin aut Marjan Hadian-Jazi verfasserin aut Max O. Wiedorn verfasserin aut Dominik Oberthür verfasserin aut Hugh Marman verfasserin aut Luigi Adriano verfasserin aut Nasser Al-Qudami verfasserin aut Saša Bajt verfasserin aut Imrich Barák verfasserin aut Sadia Bari verfasserin aut Johan Bielecki verfasserin aut Sandor Brockhauser verfasserin aut Mathew A. Coleman verfasserin aut Francisco Cruz-Mazo verfasserin aut Cyril Danilevski verfasserin aut Katerina Dörner verfasserin aut Alfonso M. Gañán-Calvo verfasserin aut Rita Graceffa verfasserin aut Hans Fanghor verfasserin aut Michael Heymann verfasserin aut Matthias Frank verfasserin aut Alexander Kaukher verfasserin aut Yoonhee Kim verfasserin aut Bostjan Kobe verfasserin aut Juraj Knoška verfasserin aut Torsten Laurus verfasserin aut Romain Letrun verfasserin aut Luis Maia verfasserin aut Marc Messerschmidt verfasserin aut Markus Metz verfasserin aut Thomas Michelat verfasserin aut Grant Mills verfasserin aut Serguei Molodtsov verfasserin aut Diana C. F. Monteiro verfasserin aut Andrew J. Morgan verfasserin aut Astrid Münnich verfasserin aut Gisel E. Peña Murillo verfasserin aut Gianpietro Previtali verfasserin aut Adam Round verfasserin aut Tokushi Sato verfasserin aut Robin Schubert verfasserin aut Joachim Schulz verfasserin aut Megan Shelby verfasserin aut Carolin Seuring verfasserin aut Jonas A. Sellberg verfasserin aut Marcin Sikorski verfasserin aut Alessandro Silenzi verfasserin aut Stephan Stern verfasserin aut Jola Sztuk-Dambietz verfasserin aut Janusz Szuba verfasserin aut Martin Trebbin verfasserin aut Patrick Vagovic verfasserin aut Thomas Ve verfasserin aut Britta Weinhausen verfasserin aut Krzysztof Wrona verfasserin aut Paul Lourdu Xavier verfasserin aut Chen Xu verfasserin aut Oleksandr Yefanov verfasserin aut Keith A. Nugent verfasserin aut Henry N. Chapman verfasserin aut Adrian P. Mancuso verfasserin aut Anton Barty verfasserin aut Brian Abbey verfasserin aut Connie Darmanin verfasserin aut In Nature Communications Nature Portfolio, 2016 13(2022), 1, Seite 13 (DE-627)626457688 (DE-600)2553671-0 20411723 nnns volume:13 year:2022 number:1 pages:13 https://doi.org/10.1038/s41467-022-32434-6 kostenfrei https://doaj.org/article/2126addb96a243bbab803f29ff675139 kostenfrei https://doi.org/10.1038/s41467-022-32434-6 kostenfrei https://doaj.org/toc/2041-1723 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_211 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_2110 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 13 2022 1 13 |
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10.1038/s41467-022-32434-6 doi (DE-627)DOAJ015553744 (DE-599)DOAJ2126addb96a243bbab803f29ff675139 DE-627 ger DE-627 rakwb eng Susannah Holmes verfasserin aut Megahertz pulse trains enable multi-hit serial femtosecond crystallography experiments at X-ray free electron lasers 2022 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Free-electron lasers are capable of high repetition rates and it is assumed that protein crystals often do not survive the first X-ray pulse. Here the authors address these issues with a demonstration of multi-hit serial crystallography in which multiple FEL pulses interact with the sample without destroying it. Science Q Henry J. Kirkwood verfasserin aut Richard Bean verfasserin aut Klaus Giewekemeyer verfasserin aut Andrew V. Martin verfasserin aut Marjan Hadian-Jazi verfasserin aut Max O. Wiedorn verfasserin aut Dominik Oberthür verfasserin aut Hugh Marman verfasserin aut Luigi Adriano verfasserin aut Nasser Al-Qudami verfasserin aut Saša Bajt verfasserin aut Imrich Barák verfasserin aut Sadia Bari verfasserin aut Johan Bielecki verfasserin aut Sandor Brockhauser verfasserin aut Mathew A. Coleman verfasserin aut Francisco Cruz-Mazo verfasserin aut Cyril Danilevski verfasserin aut Katerina Dörner verfasserin aut Alfonso M. Gañán-Calvo verfasserin aut Rita Graceffa verfasserin aut Hans Fanghor verfasserin aut Michael Heymann verfasserin aut Matthias Frank verfasserin aut Alexander Kaukher verfasserin aut Yoonhee Kim verfasserin aut Bostjan Kobe verfasserin aut Juraj Knoška verfasserin aut Torsten Laurus verfasserin aut Romain Letrun verfasserin aut Luis Maia verfasserin aut Marc Messerschmidt verfasserin aut Markus Metz verfasserin aut Thomas Michelat verfasserin aut Grant Mills verfasserin aut Serguei Molodtsov verfasserin aut Diana C. F. Monteiro verfasserin aut Andrew J. Morgan verfasserin aut Astrid Münnich verfasserin aut Gisel E. Peña Murillo verfasserin aut Gianpietro Previtali verfasserin aut Adam Round verfasserin aut Tokushi Sato verfasserin aut Robin Schubert verfasserin aut Joachim Schulz verfasserin aut Megan Shelby verfasserin aut Carolin Seuring verfasserin aut Jonas A. Sellberg verfasserin aut Marcin Sikorski verfasserin aut Alessandro Silenzi verfasserin aut Stephan Stern verfasserin aut Jola Sztuk-Dambietz verfasserin aut Janusz Szuba verfasserin aut Martin Trebbin verfasserin aut Patrick Vagovic verfasserin aut Thomas Ve verfasserin aut Britta Weinhausen verfasserin aut Krzysztof Wrona verfasserin aut Paul Lourdu Xavier verfasserin aut Chen Xu verfasserin aut Oleksandr Yefanov verfasserin aut Keith A. Nugent verfasserin aut Henry N. Chapman verfasserin aut Adrian P. Mancuso verfasserin aut Anton Barty verfasserin aut Brian Abbey verfasserin aut Connie Darmanin verfasserin aut In Nature Communications Nature Portfolio, 2016 13(2022), 1, Seite 13 (DE-627)626457688 (DE-600)2553671-0 20411723 nnns volume:13 year:2022 number:1 pages:13 https://doi.org/10.1038/s41467-022-32434-6 kostenfrei https://doaj.org/article/2126addb96a243bbab803f29ff675139 kostenfrei https://doi.org/10.1038/s41467-022-32434-6 kostenfrei https://doaj.org/toc/2041-1723 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_211 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_2110 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 13 2022 1 13 |
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Susannah Holmes @@aut@@ Henry J. Kirkwood @@aut@@ Richard Bean @@aut@@ Klaus Giewekemeyer @@aut@@ Andrew V. Martin @@aut@@ Marjan Hadian-Jazi @@aut@@ Max O. Wiedorn @@aut@@ Dominik Oberthür @@aut@@ Hugh Marman @@aut@@ Luigi Adriano @@aut@@ Nasser Al-Qudami @@aut@@ Saša Bajt @@aut@@ Imrich Barák @@aut@@ Sadia Bari @@aut@@ Johan Bielecki @@aut@@ Sandor Brockhauser @@aut@@ Mathew A. Coleman @@aut@@ Francisco Cruz-Mazo @@aut@@ Cyril Danilevski @@aut@@ Katerina Dörner @@aut@@ Alfonso M. Gañán-Calvo @@aut@@ Rita Graceffa @@aut@@ Hans Fanghor @@aut@@ Michael Heymann @@aut@@ Matthias Frank @@aut@@ Alexander Kaukher @@aut@@ Yoonhee Kim @@aut@@ Bostjan Kobe @@aut@@ Juraj Knoška @@aut@@ Torsten Laurus @@aut@@ Romain Letrun @@aut@@ Luis Maia @@aut@@ Marc Messerschmidt @@aut@@ Markus Metz @@aut@@ Thomas Michelat @@aut@@ Grant Mills @@aut@@ Serguei Molodtsov @@aut@@ Diana C. F. Monteiro @@aut@@ Andrew J. Morgan @@aut@@ Astrid Münnich @@aut@@ Gisel E. Peña Murillo @@aut@@ Gianpietro Previtali @@aut@@ Adam Round @@aut@@ Tokushi Sato @@aut@@ Robin Schubert @@aut@@ Joachim Schulz @@aut@@ Megan Shelby @@aut@@ Carolin Seuring @@aut@@ Jonas A. Sellberg @@aut@@ Marcin Sikorski @@aut@@ Alessandro Silenzi @@aut@@ Stephan Stern @@aut@@ Jola Sztuk-Dambietz @@aut@@ Janusz Szuba @@aut@@ Martin Trebbin @@aut@@ Patrick Vagovic @@aut@@ Thomas Ve @@aut@@ Britta Weinhausen @@aut@@ Krzysztof Wrona @@aut@@ Paul Lourdu Xavier @@aut@@ Chen Xu @@aut@@ Oleksandr Yefanov @@aut@@ Keith A. Nugent @@aut@@ Henry N. Chapman @@aut@@ Adrian P. Mancuso @@aut@@ Anton Barty @@aut@@ Brian Abbey @@aut@@ Connie Darmanin @@aut@@ |
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Susannah Holmes |
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Susannah Holmes misc Science misc Q Megahertz pulse trains enable multi-hit serial femtosecond crystallography experiments at X-ray free electron lasers |
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Megahertz pulse trains enable multi-hit serial femtosecond crystallography experiments at X-ray free electron lasers |
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Megahertz pulse trains enable multi-hit serial femtosecond crystallography experiments at X-ray free electron lasers |
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Megahertz pulse trains enable multi-hit serial femtosecond crystallography experiments at X-ray free electron lasers |
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Susannah Holmes Henry J. Kirkwood Richard Bean Klaus Giewekemeyer Andrew V. Martin Marjan Hadian-Jazi Max O. Wiedorn Dominik Oberthür Hugh Marman Luigi Adriano Nasser Al-Qudami Saša Bajt Imrich Barák Sadia Bari Johan Bielecki Sandor Brockhauser Mathew A. Coleman Francisco Cruz-Mazo Cyril Danilevski Katerina Dörner Alfonso M. Gañán-Calvo Rita Graceffa Hans Fanghor Michael Heymann Matthias Frank Alexander Kaukher Yoonhee Kim Bostjan Kobe Juraj Knoška Torsten Laurus Romain Letrun Luis Maia Marc Messerschmidt Markus Metz Thomas Michelat Grant Mills Serguei Molodtsov Diana C. F. Monteiro Andrew J. Morgan Astrid Münnich Gisel E. Peña Murillo Gianpietro Previtali Adam Round Tokushi Sato Robin Schubert Joachim Schulz Megan Shelby Carolin Seuring Jonas A. Sellberg Marcin Sikorski Alessandro Silenzi Stephan Stern Jola Sztuk-Dambietz Janusz Szuba Martin Trebbin Patrick Vagovic Thomas Ve Britta Weinhausen Krzysztof Wrona Paul Lourdu Xavier Chen Xu Oleksandr Yefanov Keith A. Nugent Henry N. Chapman Adrian P. Mancuso Anton Barty Brian Abbey Connie Darmanin |
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megahertz pulse trains enable multi-hit serial femtosecond crystallography experiments at x-ray free electron lasers |
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Megahertz pulse trains enable multi-hit serial femtosecond crystallography experiments at X-ray free electron lasers |
| abstract |
Free-electron lasers are capable of high repetition rates and it is assumed that protein crystals often do not survive the first X-ray pulse. Here the authors address these issues with a demonstration of multi-hit serial crystallography in which multiple FEL pulses interact with the sample without destroying it. |
| abstractGer |
Free-electron lasers are capable of high repetition rates and it is assumed that protein crystals often do not survive the first X-ray pulse. Here the authors address these issues with a demonstration of multi-hit serial crystallography in which multiple FEL pulses interact with the sample without destroying it. |
| abstract_unstemmed |
Free-electron lasers are capable of high repetition rates and it is assumed that protein crystals often do not survive the first X-ray pulse. Here the authors address these issues with a demonstration of multi-hit serial crystallography in which multiple FEL pulses interact with the sample without destroying it. |
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Megahertz pulse trains enable multi-hit serial femtosecond crystallography experiments at X-ray free electron lasers |
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