Endothelial Phosphatase VE-PTP Participates in Vasculogenic Mimicry by Preventing Autophagic Degradation of VE-Cadherin

Aberrant extra-vascular expression of VE-cadherin has been observed in metastasis associated with Vasculogenic Mimicry (VM); we have recently shown that in VM prone cells VE-cadherin is mainly in the form of phospho-VE-cadherin in Y658 allowing increased plasticity that potentiates VM development in...
Ausführliche Beschreibung

Gespeichert in:
Autor*in:

Daniel Delgado-Bellido [verfasserIn]

Concepción Bueno-Galera [verfasserIn]

Laura López-Jiménez [verfasserIn]

Angel Garcia-Diaz [verfasserIn]

F. Javier Oliver [verfasserIn]

Format:

E-Artikel

Sprache:

Englisch

Erschienen:

2020

Schlagwörter:

vasculogenic mimicry (VM)

VE-PTP

vascular endothelial receptor protein tyrosine phosphatase

VE-cadherin

melanoma

autophagy

Übergeordnetes Werk:

In: Frontiers in Oncology - Frontiers Media S.A., 2012, 10(2020)

Übergeordnetes Werk:

volume:10 ; year:2020

Links:

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Journal toc

DOI / URN:

10.3389/fonc.2020.00018

Katalog-ID:

DOAJ015906647

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