In vitro antioxidant, anti-mutagenic, anti-cancer and anti-angiogenic effects of Chinese Bowl tea

The in vitro bioactivities of Chinese Bowl tea for its antioxidant, anti-mutagenic, anti-cancer and anti-angiogenic effects were investigated. The tea extract showed high antioxidant activity both in the DPPH and hydroxyl radical scavenging activities. At concentrations of 1.25 and 2.5 mg/plate, the...
Ausführliche Beschreibung

Gespeichert in:

Autor*in:	Xin Zhao [verfasserIn] Qiang Wang [verfasserIn] Guijie Li [verfasserIn] Feng Chen [verfasserIn] Yu Qian [verfasserIn] Rui Wang [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2014

Schlagwörter:	Chinese Bowl tea LC–MS Anti-mutagenicity Anti-cancer Anti-inflammatory Beta-resorcylic acid

Übergeordnetes Werk:	In: Journal of Functional Foods - Elsevier, 2021, 7(2014), Seite 590-598
Übergeordnetes Werk:	volume:7 ; year:2014 ; pages:590-598

Links:	Link aufrufen Link aufrufen Link aufrufen Journal toc

DOI / URN:	10.1016/j.jff.2013.12.026

Katalog-ID:	DOAJ015999025

Internformat


LEADER	01000caa a22002652 4500
001	DOAJ015999025
003	DE-627
005	20230502232315.0
007	cr uuu---uuuuu
008	230226s2014 xx \|\|\|\|\|o 00\| \|\|eng c
024	7		\|a 10.1016/j.jff.2013.12.026 \|2 doi
035			\|a (DE-627)DOAJ015999025
035			\|a (DE-599)DOAJdd7aef57af6d49809bd3619463a97798
040			\|a DE-627 \|b ger \|c DE-627 \|e rakwb
041			\|a eng
050		0	\|a TX341-641
100	0		\|a Xin Zhao \|e verfasserin \|4 aut
245	1	0	\|a In vitro antioxidant, anti-mutagenic, anti-cancer and anti-angiogenic effects of Chinese Bowl tea
264		1	\|c 2014
336			\|a Text \|b txt \|2 rdacontent
337			\|a Computermedien \|b c \|2 rdamedia
338			\|a Online-Ressource \|b cr \|2 rdacarrier
520			\|a The in vitro bioactivities of Chinese Bowl tea for its antioxidant, anti-mutagenic, anti-cancer and anti-angiogenic effects were investigated. The tea extract showed high antioxidant activity both in the DPPH and hydroxyl radical scavenging activities. At concentrations of 1.25 and 2.5 mg/plate, the tea extract exhibited an anti-mutagenicity induced by MNNG (N-methyl-N′-nitro-N-nitrosoguanidine) against the Salmonella typhimurium TA100 strain. High concentration (200 μg/mL) of the tea extract significantly induced apoptosis in human tongue carcinoma TCA8113 cells by upregulating Bax, caspase-3, and caspase-9, and downregulating Bcl-2. The expression of genes associated with inflammation, e.g., NF-κB, iNOS, and COX-2, was significantly downregulated by the tea extract, demonstrating its anti-inflammatory properties. In addition, the tea showed strong anti-angiogenic effect at high concentrations. Moreover, LC–MS/MS analysis showed that gallic acid, beta-resorcylic acid, quercetin and kaempferol and their derivatives may contribute to the above mentioned effects. Especially beta-resorcylic acid showed strong anticancer effect in vitro. Beta-resorcylic acid was tested by MTT and RT-PCR assays. 100 μg/mL beta-resorcylic acid showed the effect as 200 μg/mL Bowl tea did, which indicated that it is an important compound in Bowl tea.
650		4	\|a Chinese Bowl tea
650		4	\|a LC–MS
650		4	\|a Anti-mutagenicity
650		4	\|a Anti-cancer
650		4	\|a Anti-inflammatory
650		4	\|a Beta-resorcylic acid
653		0	\|a Nutrition. Foods and food supply
700	0		\|a Qiang Wang \|e verfasserin \|4 aut
700	0		\|a Guijie Li \|e verfasserin \|4 aut
700	0		\|a Feng Chen \|e verfasserin \|4 aut
700	0		\|a Yu Qian \|e verfasserin \|4 aut
700	0		\|a Rui Wang \|e verfasserin \|4 aut
773	0	8	\|i In \|t Journal of Functional Foods \|d Elsevier, 2021 \|g 7(2014), Seite 590-598 \|w (DE-627)587138432 \|w (DE-600)2467241-5 \|x 22149414 \|7 nnns
773	1	8	\|g volume:7 \|g year:2014 \|g pages:590-598
856	4	0	\|u https://doi.org/10.1016/j.jff.2013.12.026 \|z kostenfrei
856	4	0	\|u https://doaj.org/article/dd7aef57af6d49809bd3619463a97798 \|z kostenfrei
856	4	0	\|u http://www.sciencedirect.com/science/article/pii/S1756464613003204 \|z kostenfrei
856	4	2	\|u https://doaj.org/toc/1756-4646 \|y Journal toc \|z kostenfrei
912			\|a GBV_USEFLAG_A
912			\|a SYSFLAG_A
912			\|a GBV_DOAJ
912			\|a SSG-OLC-PHA
912			\|a GBV_ILN_20
912			\|a GBV_ILN_22
912			\|a GBV_ILN_23
912			\|a GBV_ILN_24
912			\|a GBV_ILN_31
912			\|a GBV_ILN_32
912			\|a GBV_ILN_40
912			\|a GBV_ILN_60
912			\|a GBV_ILN_62
912			\|a GBV_ILN_63
912			\|a GBV_ILN_65
912			\|a GBV_ILN_69
912			\|a GBV_ILN_70
912			\|a GBV_ILN_73
912			\|a GBV_ILN_74
912			\|a GBV_ILN_90
912			\|a GBV_ILN_95
912			\|a GBV_ILN_100
912			\|a GBV_ILN_101
912			\|a GBV_ILN_105
912			\|a GBV_ILN_110
912			\|a GBV_ILN_150
912			\|a GBV_ILN_151
912			\|a GBV_ILN_165
912			\|a GBV_ILN_187
912			\|a GBV_ILN_213
912			\|a GBV_ILN_224
912			\|a GBV_ILN_230
912			\|a GBV_ILN_370
912			\|a GBV_ILN_602
912			\|a GBV_ILN_702
912			\|a GBV_ILN_2003
912			\|a GBV_ILN_2004
912			\|a GBV_ILN_2005
912			\|a GBV_ILN_2006
912			\|a GBV_ILN_2007
912			\|a GBV_ILN_2008
912			\|a GBV_ILN_2009
912			\|a GBV_ILN_2010
912			\|a GBV_ILN_2011
912			\|a GBV_ILN_2014
912			\|a GBV_ILN_2015
912			\|a GBV_ILN_2020
912			\|a GBV_ILN_2021
912			\|a GBV_ILN_2025
912			\|a GBV_ILN_2027
912			\|a GBV_ILN_2034
912			\|a GBV_ILN_2038
912			\|a GBV_ILN_2044
912			\|a GBV_ILN_2048
912			\|a GBV_ILN_2049
912			\|a GBV_ILN_2050
912			\|a GBV_ILN_2056
912			\|a GBV_ILN_2059
912			\|a GBV_ILN_2061
912			\|a GBV_ILN_2064
912			\|a GBV_ILN_2065
912			\|a GBV_ILN_2068
912			\|a GBV_ILN_2088
912			\|a GBV_ILN_2106
912			\|a GBV_ILN_2111
912			\|a GBV_ILN_2112
912			\|a GBV_ILN_2113
912			\|a GBV_ILN_2118
912			\|a GBV_ILN_2122
912			\|a GBV_ILN_2129
912			\|a GBV_ILN_2143
912			\|a GBV_ILN_2147
912			\|a GBV_ILN_2148
912			\|a GBV_ILN_2152
912			\|a GBV_ILN_2153
912			\|a GBV_ILN_2190
912			\|a GBV_ILN_2232
912			\|a GBV_ILN_2470
912			\|a GBV_ILN_2507
912			\|a GBV_ILN_2522
912			\|a GBV_ILN_4035
912			\|a GBV_ILN_4037
912			\|a GBV_ILN_4112
912			\|a GBV_ILN_4125
912			\|a GBV_ILN_4126
912			\|a GBV_ILN_4242
912			\|a GBV_ILN_4251
912			\|a GBV_ILN_4305
912			\|a GBV_ILN_4313
912			\|a GBV_ILN_4322
912			\|a GBV_ILN_4323
912			\|a GBV_ILN_4324
912			\|a GBV_ILN_4325
912			\|a GBV_ILN_4326
912			\|a GBV_ILN_4333
912			\|a GBV_ILN_4334
912			\|a GBV_ILN_4335
912			\|a GBV_ILN_4338
912			\|a GBV_ILN_4393
912			\|a GBV_ILN_4700
951			\|a AR
952			\|d 7 \|j 2014 \|h 590-598

Indexfelder

author_variant	x z xz q w qw g l gl f c fc y q yq r w rw
matchkey_str	article:22149414:2014----::niratoiatniuaeiatcneadninigncf
hierarchy_sort_str	2014
callnumber-subject-code	TX
publishDate	2014
allfields	10.1016/j.jff.2013.12.026 doi (DE-627)DOAJ015999025 (DE-599)DOAJdd7aef57af6d49809bd3619463a97798 DE-627 ger DE-627 rakwb eng TX341-641 Xin Zhao verfasserin aut In vitro antioxidant, anti-mutagenic, anti-cancer and anti-angiogenic effects of Chinese Bowl tea 2014 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier The in vitro bioactivities of Chinese Bowl tea for its antioxidant, anti-mutagenic, anti-cancer and anti-angiogenic effects were investigated. The tea extract showed high antioxidant activity both in the DPPH and hydroxyl radical scavenging activities. At concentrations of 1.25 and 2.5 mg/plate, the tea extract exhibited an anti-mutagenicity induced by MNNG (N-methyl-N′-nitro-N-nitrosoguanidine) against the Salmonella typhimurium TA100 strain. High concentration (200 μg/mL) of the tea extract significantly induced apoptosis in human tongue carcinoma TCA8113 cells by upregulating Bax, caspase-3, and caspase-9, and downregulating Bcl-2. The expression of genes associated with inflammation, e.g., NF-κB, iNOS, and COX-2, was significantly downregulated by the tea extract, demonstrating its anti-inflammatory properties. In addition, the tea showed strong anti-angiogenic effect at high concentrations. Moreover, LC–MS/MS analysis showed that gallic acid, beta-resorcylic acid, quercetin and kaempferol and their derivatives may contribute to the above mentioned effects. Especially beta-resorcylic acid showed strong anticancer effect in vitro. Beta-resorcylic acid was tested by MTT and RT-PCR assays. 100 μg/mL beta-resorcylic acid showed the effect as 200 μg/mL Bowl tea did, which indicated that it is an important compound in Bowl tea. Chinese Bowl tea LC–MS Anti-mutagenicity Anti-cancer Anti-inflammatory Beta-resorcylic acid Nutrition. Foods and food supply Qiang Wang verfasserin aut Guijie Li verfasserin aut Feng Chen verfasserin aut Yu Qian verfasserin aut Rui Wang verfasserin aut In Journal of Functional Foods Elsevier, 2021 7(2014), Seite 590-598 (DE-627)587138432 (DE-600)2467241-5 22149414 nnns volume:7 year:2014 pages:590-598 https://doi.org/10.1016/j.jff.2013.12.026 kostenfrei https://doaj.org/article/dd7aef57af6d49809bd3619463a97798 kostenfrei http://www.sciencedirect.com/science/article/pii/S1756464613003204 kostenfrei https://doaj.org/toc/1756-4646 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_150 GBV_ILN_151 GBV_ILN_165 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2088 GBV_ILN_2106 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 7 2014 590-598
spelling	10.1016/j.jff.2013.12.026 doi (DE-627)DOAJ015999025 (DE-599)DOAJdd7aef57af6d49809bd3619463a97798 DE-627 ger DE-627 rakwb eng TX341-641 Xin Zhao verfasserin aut In vitro antioxidant, anti-mutagenic, anti-cancer and anti-angiogenic effects of Chinese Bowl tea 2014 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier The in vitro bioactivities of Chinese Bowl tea for its antioxidant, anti-mutagenic, anti-cancer and anti-angiogenic effects were investigated. The tea extract showed high antioxidant activity both in the DPPH and hydroxyl radical scavenging activities. At concentrations of 1.25 and 2.5 mg/plate, the tea extract exhibited an anti-mutagenicity induced by MNNG (N-methyl-N′-nitro-N-nitrosoguanidine) against the Salmonella typhimurium TA100 strain. High concentration (200 μg/mL) of the tea extract significantly induced apoptosis in human tongue carcinoma TCA8113 cells by upregulating Bax, caspase-3, and caspase-9, and downregulating Bcl-2. The expression of genes associated with inflammation, e.g., NF-κB, iNOS, and COX-2, was significantly downregulated by the tea extract, demonstrating its anti-inflammatory properties. In addition, the tea showed strong anti-angiogenic effect at high concentrations. Moreover, LC–MS/MS analysis showed that gallic acid, beta-resorcylic acid, quercetin and kaempferol and their derivatives may contribute to the above mentioned effects. Especially beta-resorcylic acid showed strong anticancer effect in vitro. Beta-resorcylic acid was tested by MTT and RT-PCR assays. 100 μg/mL beta-resorcylic acid showed the effect as 200 μg/mL Bowl tea did, which indicated that it is an important compound in Bowl tea. Chinese Bowl tea LC–MS Anti-mutagenicity Anti-cancer Anti-inflammatory Beta-resorcylic acid Nutrition. Foods and food supply Qiang Wang verfasserin aut Guijie Li verfasserin aut Feng Chen verfasserin aut Yu Qian verfasserin aut Rui Wang verfasserin aut In Journal of Functional Foods Elsevier, 2021 7(2014), Seite 590-598 (DE-627)587138432 (DE-600)2467241-5 22149414 nnns volume:7 year:2014 pages:590-598 https://doi.org/10.1016/j.jff.2013.12.026 kostenfrei https://doaj.org/article/dd7aef57af6d49809bd3619463a97798 kostenfrei http://www.sciencedirect.com/science/article/pii/S1756464613003204 kostenfrei https://doaj.org/toc/1756-4646 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_150 GBV_ILN_151 GBV_ILN_165 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2088 GBV_ILN_2106 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 7 2014 590-598
allfields_unstemmed	10.1016/j.jff.2013.12.026 doi (DE-627)DOAJ015999025 (DE-599)DOAJdd7aef57af6d49809bd3619463a97798 DE-627 ger DE-627 rakwb eng TX341-641 Xin Zhao verfasserin aut In vitro antioxidant, anti-mutagenic, anti-cancer and anti-angiogenic effects of Chinese Bowl tea 2014 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier The in vitro bioactivities of Chinese Bowl tea for its antioxidant, anti-mutagenic, anti-cancer and anti-angiogenic effects were investigated. The tea extract showed high antioxidant activity both in the DPPH and hydroxyl radical scavenging activities. At concentrations of 1.25 and 2.5 mg/plate, the tea extract exhibited an anti-mutagenicity induced by MNNG (N-methyl-N′-nitro-N-nitrosoguanidine) against the Salmonella typhimurium TA100 strain. High concentration (200 μg/mL) of the tea extract significantly induced apoptosis in human tongue carcinoma TCA8113 cells by upregulating Bax, caspase-3, and caspase-9, and downregulating Bcl-2. The expression of genes associated with inflammation, e.g., NF-κB, iNOS, and COX-2, was significantly downregulated by the tea extract, demonstrating its anti-inflammatory properties. In addition, the tea showed strong anti-angiogenic effect at high concentrations. Moreover, LC–MS/MS analysis showed that gallic acid, beta-resorcylic acid, quercetin and kaempferol and their derivatives may contribute to the above mentioned effects. Especially beta-resorcylic acid showed strong anticancer effect in vitro. Beta-resorcylic acid was tested by MTT and RT-PCR assays. 100 μg/mL beta-resorcylic acid showed the effect as 200 μg/mL Bowl tea did, which indicated that it is an important compound in Bowl tea. Chinese Bowl tea LC–MS Anti-mutagenicity Anti-cancer Anti-inflammatory Beta-resorcylic acid Nutrition. Foods and food supply Qiang Wang verfasserin aut Guijie Li verfasserin aut Feng Chen verfasserin aut Yu Qian verfasserin aut Rui Wang verfasserin aut In Journal of Functional Foods Elsevier, 2021 7(2014), Seite 590-598 (DE-627)587138432 (DE-600)2467241-5 22149414 nnns volume:7 year:2014 pages:590-598 https://doi.org/10.1016/j.jff.2013.12.026 kostenfrei https://doaj.org/article/dd7aef57af6d49809bd3619463a97798 kostenfrei http://www.sciencedirect.com/science/article/pii/S1756464613003204 kostenfrei https://doaj.org/toc/1756-4646 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_150 GBV_ILN_151 GBV_ILN_165 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2088 GBV_ILN_2106 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 7 2014 590-598
allfieldsGer	10.1016/j.jff.2013.12.026 doi (DE-627)DOAJ015999025 (DE-599)DOAJdd7aef57af6d49809bd3619463a97798 DE-627 ger DE-627 rakwb eng TX341-641 Xin Zhao verfasserin aut In vitro antioxidant, anti-mutagenic, anti-cancer and anti-angiogenic effects of Chinese Bowl tea 2014 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier The in vitro bioactivities of Chinese Bowl tea for its antioxidant, anti-mutagenic, anti-cancer and anti-angiogenic effects were investigated. The tea extract showed high antioxidant activity both in the DPPH and hydroxyl radical scavenging activities. At concentrations of 1.25 and 2.5 mg/plate, the tea extract exhibited an anti-mutagenicity induced by MNNG (N-methyl-N′-nitro-N-nitrosoguanidine) against the Salmonella typhimurium TA100 strain. High concentration (200 μg/mL) of the tea extract significantly induced apoptosis in human tongue carcinoma TCA8113 cells by upregulating Bax, caspase-3, and caspase-9, and downregulating Bcl-2. The expression of genes associated with inflammation, e.g., NF-κB, iNOS, and COX-2, was significantly downregulated by the tea extract, demonstrating its anti-inflammatory properties. In addition, the tea showed strong anti-angiogenic effect at high concentrations. Moreover, LC–MS/MS analysis showed that gallic acid, beta-resorcylic acid, quercetin and kaempferol and their derivatives may contribute to the above mentioned effects. Especially beta-resorcylic acid showed strong anticancer effect in vitro. Beta-resorcylic acid was tested by MTT and RT-PCR assays. 100 μg/mL beta-resorcylic acid showed the effect as 200 μg/mL Bowl tea did, which indicated that it is an important compound in Bowl tea. Chinese Bowl tea LC–MS Anti-mutagenicity Anti-cancer Anti-inflammatory Beta-resorcylic acid Nutrition. Foods and food supply Qiang Wang verfasserin aut Guijie Li verfasserin aut Feng Chen verfasserin aut Yu Qian verfasserin aut Rui Wang verfasserin aut In Journal of Functional Foods Elsevier, 2021 7(2014), Seite 590-598 (DE-627)587138432 (DE-600)2467241-5 22149414 nnns volume:7 year:2014 pages:590-598 https://doi.org/10.1016/j.jff.2013.12.026 kostenfrei https://doaj.org/article/dd7aef57af6d49809bd3619463a97798 kostenfrei http://www.sciencedirect.com/science/article/pii/S1756464613003204 kostenfrei https://doaj.org/toc/1756-4646 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_150 GBV_ILN_151 GBV_ILN_165 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2088 GBV_ILN_2106 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 7 2014 590-598
allfieldsSound	10.1016/j.jff.2013.12.026 doi (DE-627)DOAJ015999025 (DE-599)DOAJdd7aef57af6d49809bd3619463a97798 DE-627 ger DE-627 rakwb eng TX341-641 Xin Zhao verfasserin aut In vitro antioxidant, anti-mutagenic, anti-cancer and anti-angiogenic effects of Chinese Bowl tea 2014 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier The in vitro bioactivities of Chinese Bowl tea for its antioxidant, anti-mutagenic, anti-cancer and anti-angiogenic effects were investigated. The tea extract showed high antioxidant activity both in the DPPH and hydroxyl radical scavenging activities. At concentrations of 1.25 and 2.5 mg/plate, the tea extract exhibited an anti-mutagenicity induced by MNNG (N-methyl-N′-nitro-N-nitrosoguanidine) against the Salmonella typhimurium TA100 strain. High concentration (200 μg/mL) of the tea extract significantly induced apoptosis in human tongue carcinoma TCA8113 cells by upregulating Bax, caspase-3, and caspase-9, and downregulating Bcl-2. The expression of genes associated with inflammation, e.g., NF-κB, iNOS, and COX-2, was significantly downregulated by the tea extract, demonstrating its anti-inflammatory properties. In addition, the tea showed strong anti-angiogenic effect at high concentrations. Moreover, LC–MS/MS analysis showed that gallic acid, beta-resorcylic acid, quercetin and kaempferol and their derivatives may contribute to the above mentioned effects. Especially beta-resorcylic acid showed strong anticancer effect in vitro. Beta-resorcylic acid was tested by MTT and RT-PCR assays. 100 μg/mL beta-resorcylic acid showed the effect as 200 μg/mL Bowl tea did, which indicated that it is an important compound in Bowl tea. Chinese Bowl tea LC–MS Anti-mutagenicity Anti-cancer Anti-inflammatory Beta-resorcylic acid Nutrition. Foods and food supply Qiang Wang verfasserin aut Guijie Li verfasserin aut Feng Chen verfasserin aut Yu Qian verfasserin aut Rui Wang verfasserin aut In Journal of Functional Foods Elsevier, 2021 7(2014), Seite 590-598 (DE-627)587138432 (DE-600)2467241-5 22149414 nnns volume:7 year:2014 pages:590-598 https://doi.org/10.1016/j.jff.2013.12.026 kostenfrei https://doaj.org/article/dd7aef57af6d49809bd3619463a97798 kostenfrei http://www.sciencedirect.com/science/article/pii/S1756464613003204 kostenfrei https://doaj.org/toc/1756-4646 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_150 GBV_ILN_151 GBV_ILN_165 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2088 GBV_ILN_2106 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700 AR 7 2014 590-598
language	English
source	In Journal of Functional Foods 7(2014), Seite 590-598 volume:7 year:2014 pages:590-598
sourceStr	In Journal of Functional Foods 7(2014), Seite 590-598 volume:7 year:2014 pages:590-598
format_phy_str_mv	Article
institution	findex.gbv.de
topic_facet	Chinese Bowl tea LC–MS Anti-mutagenicity Anti-cancer Anti-inflammatory Beta-resorcylic acid Nutrition. Foods and food supply
isfreeaccess_bool	true
container_title	Journal of Functional Foods
authorswithroles_txt_mv	Xin Zhao @@aut@@ Qiang Wang @@aut@@ Guijie Li @@aut@@ Feng Chen @@aut@@ Yu Qian @@aut@@ Rui Wang @@aut@@
publishDateDaySort_date	2014-01-01T00:00:00Z
hierarchy_top_id	587138432
id	DOAJ015999025
language_de	englisch
fullrecord	<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000caa a22002652 4500</leader><controlfield tag="001">DOAJ015999025</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20230502232315.0</controlfield><controlfield tag="007">cr uuu---uuuuu</controlfield><controlfield tag="008">230226s2014 xx \|\|\|\|\|o 00\| \|\|eng c</controlfield><datafield tag="024" ind1="7" ind2=" "><subfield code="a">10.1016/j.jff.2013.12.026</subfield><subfield code="2">doi</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)DOAJ015999025</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-599)DOAJdd7aef57af6d49809bd3619463a97798</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="041" ind1=" " ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="050" ind1=" " ind2="0"><subfield code="a">TX341-641</subfield></datafield><datafield tag="100" ind1="0" ind2=" "><subfield code="a">Xin Zhao</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">In vitro antioxidant, anti-mutagenic, anti-cancer and anti-angiogenic effects of Chinese Bowl tea</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="c">2014</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">Text</subfield><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">Computermedien</subfield><subfield code="b">c</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">Online-Ressource</subfield><subfield code="b">cr</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">The in vitro bioactivities of Chinese Bowl tea for its antioxidant, anti-mutagenic, anti-cancer and anti-angiogenic effects were investigated. The tea extract showed high antioxidant activity both in the DPPH and hydroxyl radical scavenging activities. At concentrations of 1.25 and 2.5 mg/plate, the tea extract exhibited an anti-mutagenicity induced by MNNG (N-methyl-N′-nitro-N-nitrosoguanidine) against the Salmonella typhimurium TA100 strain. High concentration (200 μg/mL) of the tea extract significantly induced apoptosis in human tongue carcinoma TCA8113 cells by upregulating Bax, caspase-3, and caspase-9, and downregulating Bcl-2. The expression of genes associated with inflammation, e.g., NF-κB, iNOS, and COX-2, was significantly downregulated by the tea extract, demonstrating its anti-inflammatory properties. In addition, the tea showed strong anti-angiogenic effect at high concentrations. Moreover, LC–MS/MS analysis showed that gallic acid, beta-resorcylic acid, quercetin and kaempferol and their derivatives may contribute to the above mentioned effects. Especially beta-resorcylic acid showed strong anticancer effect in vitro. Beta-resorcylic acid was tested by MTT and RT-PCR assays. 100 μg/mL beta-resorcylic acid showed the effect as 200 μg/mL Bowl tea did, which indicated that it is an important compound in Bowl tea.</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Chinese Bowl tea</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">LC–MS</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Anti-mutagenicity</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Anti-cancer</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Anti-inflammatory</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Beta-resorcylic acid</subfield></datafield><datafield tag="653" ind1=" " ind2="0"><subfield code="a">Nutrition. Foods and food supply</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Qiang Wang</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Guijie Li</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Feng Chen</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Yu Qian</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Rui Wang</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="773" ind1="0" ind2="8"><subfield code="i">In</subfield><subfield code="t">Journal of Functional Foods</subfield><subfield code="d">Elsevier, 2021</subfield><subfield code="g">7(2014), Seite 590-598</subfield><subfield code="w">(DE-627)587138432</subfield><subfield code="w">(DE-600)2467241-5</subfield><subfield code="x">22149414</subfield><subfield code="7">nnns</subfield></datafield><datafield tag="773" ind1="1" ind2="8"><subfield code="g">volume:7</subfield><subfield code="g">year:2014</subfield><subfield code="g">pages:590-598</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">https://doi.org/10.1016/j.jff.2013.12.026</subfield><subfield code="z">kostenfrei</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">https://doaj.org/article/dd7aef57af6d49809bd3619463a97798</subfield><subfield code="z">kostenfrei</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">http://www.sciencedirect.com/science/article/pii/S1756464613003204</subfield><subfield code="z">kostenfrei</subfield></datafield><datafield tag="856" ind1="4" ind2="2"><subfield code="u">https://doaj.org/toc/1756-4646</subfield><subfield code="y">Journal toc</subfield><subfield code="z">kostenfrei</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_USEFLAG_A</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">SYSFLAG_A</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_DOAJ</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">SSG-OLC-PHA</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_20</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_22</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_23</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_24</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_31</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_32</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_40</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_60</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_62</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_63</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_65</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_69</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_70</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_73</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_74</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_90</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_95</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_100</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_101</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_105</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_110</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_150</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_151</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_165</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_187</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_213</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_224</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_230</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_370</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_602</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_702</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2003</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2004</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2005</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2006</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2007</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2008</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2009</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2010</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2011</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2014</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2015</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2020</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2021</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2025</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2027</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2034</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2038</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2044</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2048</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2049</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2050</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2056</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2059</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2061</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2064</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2065</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2068</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2088</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2106</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2111</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2112</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2113</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2118</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2122</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2129</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2143</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2147</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2148</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2152</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2153</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2190</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2232</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2470</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2507</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2522</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4035</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4037</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4112</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4125</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4126</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4242</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4251</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4305</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4313</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4322</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4323</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4324</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4325</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4326</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4333</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4334</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4335</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4338</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4393</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4700</subfield></datafield><datafield tag="951" ind1=" " ind2=" "><subfield code="a">AR</subfield></datafield><datafield tag="952" ind1=" " ind2=" "><subfield code="d">7</subfield><subfield code="j">2014</subfield><subfield code="h">590-598</subfield></datafield></record></collection>
callnumber-first	T - Technology
author	Xin Zhao
spellingShingle	Xin Zhao misc TX341-641 misc Chinese Bowl tea misc LC–MS misc Anti-mutagenicity misc Anti-cancer misc Anti-inflammatory misc Beta-resorcylic acid misc Nutrition. Foods and food supply In vitro antioxidant, anti-mutagenic, anti-cancer and anti-angiogenic effects of Chinese Bowl tea
authorStr	Xin Zhao
ppnlink_with_tag_str_mv	@@773@@(DE-627)587138432
format	electronic Article
delete_txt_mv	keep
author_role	aut aut aut aut aut aut
collection	DOAJ
remote_str	true
callnumber-label	TX341-641
illustrated	Not Illustrated
issn	22149414
topic_title	TX341-641 In vitro antioxidant, anti-mutagenic, anti-cancer and anti-angiogenic effects of Chinese Bowl tea Chinese Bowl tea LC–MS Anti-mutagenicity Anti-cancer Anti-inflammatory Beta-resorcylic acid
topic	misc TX341-641 misc Chinese Bowl tea misc LC–MS misc Anti-mutagenicity misc Anti-cancer misc Anti-inflammatory misc Beta-resorcylic acid misc Nutrition. Foods and food supply
topic_unstemmed	misc TX341-641 misc Chinese Bowl tea misc LC–MS misc Anti-mutagenicity misc Anti-cancer misc Anti-inflammatory misc Beta-resorcylic acid misc Nutrition. Foods and food supply
topic_browse	misc TX341-641 misc Chinese Bowl tea misc LC–MS misc Anti-mutagenicity misc Anti-cancer misc Anti-inflammatory misc Beta-resorcylic acid misc Nutrition. Foods and food supply
format_facet	Elektronische Aufsätze Aufsätze Elektronische Ressource
format_main_str_mv	Text Zeitschrift/Artikel
carriertype_str_mv	cr
hierarchy_parent_title	Journal of Functional Foods
hierarchy_parent_id	587138432
hierarchy_top_title	Journal of Functional Foods
isfreeaccess_txt	true
familylinks_str_mv	(DE-627)587138432 (DE-600)2467241-5
title	In vitro antioxidant, anti-mutagenic, anti-cancer and anti-angiogenic effects of Chinese Bowl tea
ctrlnum	(DE-627)DOAJ015999025 (DE-599)DOAJdd7aef57af6d49809bd3619463a97798
title_full	In vitro antioxidant, anti-mutagenic, anti-cancer and anti-angiogenic effects of Chinese Bowl tea
author_sort	Xin Zhao
journal	Journal of Functional Foods
journalStr	Journal of Functional Foods
callnumber-first-code	T
lang_code	eng
isOA_bool	true
recordtype	marc
publishDateSort	2014
contenttype_str_mv	txt
container_start_page	590
author_browse	Xin Zhao Qiang Wang Guijie Li Feng Chen Yu Qian Rui Wang
container_volume	7
class	TX341-641
format_se	Elektronische Aufsätze
author-letter	Xin Zhao
doi_str_mv	10.1016/j.jff.2013.12.026
author2-role	verfasserin
title_sort	in vitro antioxidant, anti-mutagenic, anti-cancer and anti-angiogenic effects of chinese bowl tea
callnumber	TX341-641
title_auth	In vitro antioxidant, anti-mutagenic, anti-cancer and anti-angiogenic effects of Chinese Bowl tea
abstract	The in vitro bioactivities of Chinese Bowl tea for its antioxidant, anti-mutagenic, anti-cancer and anti-angiogenic effects were investigated. The tea extract showed high antioxidant activity both in the DPPH and hydroxyl radical scavenging activities. At concentrations of 1.25 and 2.5 mg/plate, the tea extract exhibited an anti-mutagenicity induced by MNNG (N-methyl-N′-nitro-N-nitrosoguanidine) against the Salmonella typhimurium TA100 strain. High concentration (200 μg/mL) of the tea extract significantly induced apoptosis in human tongue carcinoma TCA8113 cells by upregulating Bax, caspase-3, and caspase-9, and downregulating Bcl-2. The expression of genes associated with inflammation, e.g., NF-κB, iNOS, and COX-2, was significantly downregulated by the tea extract, demonstrating its anti-inflammatory properties. In addition, the tea showed strong anti-angiogenic effect at high concentrations. Moreover, LC–MS/MS analysis showed that gallic acid, beta-resorcylic acid, quercetin and kaempferol and their derivatives may contribute to the above mentioned effects. Especially beta-resorcylic acid showed strong anticancer effect in vitro. Beta-resorcylic acid was tested by MTT and RT-PCR assays. 100 μg/mL beta-resorcylic acid showed the effect as 200 μg/mL Bowl tea did, which indicated that it is an important compound in Bowl tea.
abstractGer	The in vitro bioactivities of Chinese Bowl tea for its antioxidant, anti-mutagenic, anti-cancer and anti-angiogenic effects were investigated. The tea extract showed high antioxidant activity both in the DPPH and hydroxyl radical scavenging activities. At concentrations of 1.25 and 2.5 mg/plate, the tea extract exhibited an anti-mutagenicity induced by MNNG (N-methyl-N′-nitro-N-nitrosoguanidine) against the Salmonella typhimurium TA100 strain. High concentration (200 μg/mL) of the tea extract significantly induced apoptosis in human tongue carcinoma TCA8113 cells by upregulating Bax, caspase-3, and caspase-9, and downregulating Bcl-2. The expression of genes associated with inflammation, e.g., NF-κB, iNOS, and COX-2, was significantly downregulated by the tea extract, demonstrating its anti-inflammatory properties. In addition, the tea showed strong anti-angiogenic effect at high concentrations. Moreover, LC–MS/MS analysis showed that gallic acid, beta-resorcylic acid, quercetin and kaempferol and their derivatives may contribute to the above mentioned effects. Especially beta-resorcylic acid showed strong anticancer effect in vitro. Beta-resorcylic acid was tested by MTT and RT-PCR assays. 100 μg/mL beta-resorcylic acid showed the effect as 200 μg/mL Bowl tea did, which indicated that it is an important compound in Bowl tea.
abstract_unstemmed	The in vitro bioactivities of Chinese Bowl tea for its antioxidant, anti-mutagenic, anti-cancer and anti-angiogenic effects were investigated. The tea extract showed high antioxidant activity both in the DPPH and hydroxyl radical scavenging activities. At concentrations of 1.25 and 2.5 mg/plate, the tea extract exhibited an anti-mutagenicity induced by MNNG (N-methyl-N′-nitro-N-nitrosoguanidine) against the Salmonella typhimurium TA100 strain. High concentration (200 μg/mL) of the tea extract significantly induced apoptosis in human tongue carcinoma TCA8113 cells by upregulating Bax, caspase-3, and caspase-9, and downregulating Bcl-2. The expression of genes associated with inflammation, e.g., NF-κB, iNOS, and COX-2, was significantly downregulated by the tea extract, demonstrating its anti-inflammatory properties. In addition, the tea showed strong anti-angiogenic effect at high concentrations. Moreover, LC–MS/MS analysis showed that gallic acid, beta-resorcylic acid, quercetin and kaempferol and their derivatives may contribute to the above mentioned effects. Especially beta-resorcylic acid showed strong anticancer effect in vitro. Beta-resorcylic acid was tested by MTT and RT-PCR assays. 100 μg/mL beta-resorcylic acid showed the effect as 200 μg/mL Bowl tea did, which indicated that it is an important compound in Bowl tea.
collection_details	GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_32 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_90 GBV_ILN_95 GBV_ILN_100 GBV_ILN_101 GBV_ILN_105 GBV_ILN_110 GBV_ILN_150 GBV_ILN_151 GBV_ILN_165 GBV_ILN_187 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_370 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2003 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2007 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2027 GBV_ILN_2034 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2049 GBV_ILN_2050 GBV_ILN_2056 GBV_ILN_2059 GBV_ILN_2061 GBV_ILN_2064 GBV_ILN_2065 GBV_ILN_2068 GBV_ILN_2088 GBV_ILN_2106 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2113 GBV_ILN_2118 GBV_ILN_2122 GBV_ILN_2129 GBV_ILN_2143 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_2232 GBV_ILN_2470 GBV_ILN_2507 GBV_ILN_2522 GBV_ILN_4035 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4242 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4326 GBV_ILN_4333 GBV_ILN_4334 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4393 GBV_ILN_4700
title_short	In vitro antioxidant, anti-mutagenic, anti-cancer and anti-angiogenic effects of Chinese Bowl tea
url	https://doi.org/10.1016/j.jff.2013.12.026 https://doaj.org/article/dd7aef57af6d49809bd3619463a97798 http://www.sciencedirect.com/science/article/pii/S1756464613003204 https://doaj.org/toc/1756-4646
remote_bool	true
author2	Qiang Wang Guijie Li Feng Chen Yu Qian Rui Wang
author2Str	Qiang Wang Guijie Li Feng Chen Yu Qian Rui Wang
ppnlink	587138432
callnumber-subject	TX - Home Economics
mediatype_str_mv	c
isOA_txt	true
hochschulschrift_bool	false
doi_str	10.1016/j.jff.2013.12.026
callnumber-a	TX341-641
up_date	2024-07-03T18:23:28.798Z
_version_	1803583235087663104
fullrecord_marcxml	<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000caa a22002652 4500</leader><controlfield tag="001">DOAJ015999025</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20230502232315.0</controlfield><controlfield tag="007">cr uuu---uuuuu</controlfield><controlfield tag="008">230226s2014 xx \|\|\|\|\|o 00\| \|\|eng c</controlfield><datafield tag="024" ind1="7" ind2=" "><subfield code="a">10.1016/j.jff.2013.12.026</subfield><subfield code="2">doi</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)DOAJ015999025</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-599)DOAJdd7aef57af6d49809bd3619463a97798</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="041" ind1=" " ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="050" ind1=" " ind2="0"><subfield code="a">TX341-641</subfield></datafield><datafield tag="100" ind1="0" ind2=" "><subfield code="a">Xin Zhao</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">In vitro antioxidant, anti-mutagenic, anti-cancer and anti-angiogenic effects of Chinese Bowl tea</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="c">2014</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">Text</subfield><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">Computermedien</subfield><subfield code="b">c</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">Online-Ressource</subfield><subfield code="b">cr</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">The in vitro bioactivities of Chinese Bowl tea for its antioxidant, anti-mutagenic, anti-cancer and anti-angiogenic effects were investigated. The tea extract showed high antioxidant activity both in the DPPH and hydroxyl radical scavenging activities. At concentrations of 1.25 and 2.5 mg/plate, the tea extract exhibited an anti-mutagenicity induced by MNNG (N-methyl-N′-nitro-N-nitrosoguanidine) against the Salmonella typhimurium TA100 strain. High concentration (200 μg/mL) of the tea extract significantly induced apoptosis in human tongue carcinoma TCA8113 cells by upregulating Bax, caspase-3, and caspase-9, and downregulating Bcl-2. The expression of genes associated with inflammation, e.g., NF-κB, iNOS, and COX-2, was significantly downregulated by the tea extract, demonstrating its anti-inflammatory properties. In addition, the tea showed strong anti-angiogenic effect at high concentrations. Moreover, LC–MS/MS analysis showed that gallic acid, beta-resorcylic acid, quercetin and kaempferol and their derivatives may contribute to the above mentioned effects. Especially beta-resorcylic acid showed strong anticancer effect in vitro. Beta-resorcylic acid was tested by MTT and RT-PCR assays. 100 μg/mL beta-resorcylic acid showed the effect as 200 μg/mL Bowl tea did, which indicated that it is an important compound in Bowl tea.</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Chinese Bowl tea</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">LC–MS</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Anti-mutagenicity</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Anti-cancer</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Anti-inflammatory</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Beta-resorcylic acid</subfield></datafield><datafield tag="653" ind1=" " ind2="0"><subfield code="a">Nutrition. Foods and food supply</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Qiang Wang</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Guijie Li</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Feng Chen</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Yu Qian</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Rui Wang</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="773" ind1="0" ind2="8"><subfield code="i">In</subfield><subfield code="t">Journal of Functional Foods</subfield><subfield code="d">Elsevier, 2021</subfield><subfield code="g">7(2014), Seite 590-598</subfield><subfield code="w">(DE-627)587138432</subfield><subfield code="w">(DE-600)2467241-5</subfield><subfield code="x">22149414</subfield><subfield code="7">nnns</subfield></datafield><datafield tag="773" ind1="1" ind2="8"><subfield code="g">volume:7</subfield><subfield code="g">year:2014</subfield><subfield code="g">pages:590-598</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">https://doi.org/10.1016/j.jff.2013.12.026</subfield><subfield code="z">kostenfrei</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">https://doaj.org/article/dd7aef57af6d49809bd3619463a97798</subfield><subfield code="z">kostenfrei</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">http://www.sciencedirect.com/science/article/pii/S1756464613003204</subfield><subfield code="z">kostenfrei</subfield></datafield><datafield tag="856" ind1="4" ind2="2"><subfield code="u">https://doaj.org/toc/1756-4646</subfield><subfield code="y">Journal toc</subfield><subfield code="z">kostenfrei</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_USEFLAG_A</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">SYSFLAG_A</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_DOAJ</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">SSG-OLC-PHA</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_20</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_22</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_23</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_24</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_31</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_32</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_40</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_60</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_62</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_63</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_65</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_69</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_70</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_73</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_74</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_90</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_95</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_100</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_101</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_105</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_110</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_150</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_151</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_165</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_187</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_213</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_224</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_230</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_370</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_602</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_702</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2003</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2004</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2005</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2006</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2007</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2008</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2009</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2010</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2011</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2014</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2015</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2020</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2021</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2025</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2027</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2034</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2038</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2044</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2048</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2049</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2050</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2056</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2059</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2061</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2064</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2065</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2068</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2088</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2106</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2111</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2112</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2113</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2118</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2122</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2129</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2143</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2147</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2148</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2152</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2153</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2190</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2232</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2470</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2507</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2522</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4035</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4037</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4112</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4125</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4126</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4242</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4251</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4305</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4313</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4322</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4323</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4324</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4325</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4326</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4333</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4334</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4335</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4338</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4393</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4700</subfield></datafield><datafield tag="951" ind1=" " ind2=" "><subfield code="a">AR</subfield></datafield><datafield tag="952" ind1=" " ind2=" "><subfield code="d">7</subfield><subfield code="j">2014</subfield><subfield code="h">590-598</subfield></datafield></record></collection>
score	7.4002275

Nicht das Richtige dabei?

Schreiben Sie uns!

In vitro antioxidant, anti-mutagenic, anti-cancer and anti-angiogenic effects of Chinese Bowl tea

Nicht das Richtige dabei?

Zugang & Verfügbarkeit

Vorhandene Bände

Nicht das Richtige dabei?