Advances in Quantitative Imaging of Genetic and Acquired Myopathies: Clinical Applications and Perspectives

In the last years, magnetic resonance imaging (MRI) has become fundamental for the diagnosis and monitoring of myopathies given its ability to show the severity and distribution of pathology, to identify specific patterns of damage distribution and to properly interpret a number of genetic variants....
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Autor*in:	Matteo Paoletti [verfasserIn] Anna Pichiecchio [verfasserIn] Stefano Cotti Piccinelli [verfasserIn] Giorgio Tasca [verfasserIn] Angela L. Berardinelli [verfasserIn] Alessandro Padovani [verfasserIn] Massimiliano Filosto [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2019

Schlagwörter:	muscular imaging neuromuscular diseases MRI myopathy advanced imaging

Übergeordnetes Werk:	In: Frontiers in Neurology - Frontiers Media S.A., 2010, 10(2019)
Übergeordnetes Werk:	volume:10 ; year:2019

Links:	Link aufrufen Link aufrufen Link aufrufen Journal toc

DOI / URN:	10.3389/fneur.2019.00078

Katalog-ID:	DOAJ01647614X

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language	English
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authorswithroles_txt_mv	Matteo Paoletti @@aut@@ Anna Pichiecchio @@aut@@ Stefano Cotti Piccinelli @@aut@@ Giorgio Tasca @@aut@@ Angela L. Berardinelli @@aut@@ Alessandro Padovani @@aut@@ Massimiliano Filosto @@aut@@
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topic_title	RC346-429 Advances in Quantitative Imaging of Genetic and Acquired Myopathies: Clinical Applications and Perspectives muscular imaging neuromuscular diseases MRI myopathy advanced imaging
topic	misc RC346-429 misc muscular imaging misc neuromuscular diseases misc MRI misc myopathy misc advanced imaging misc Neurology. Diseases of the nervous system
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title	Advances in Quantitative Imaging of Genetic and Acquired Myopathies: Clinical Applications and Perspectives
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title_sort	advances in quantitative imaging of genetic and acquired myopathies: clinical applications and perspectives
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title_auth	Advances in Quantitative Imaging of Genetic and Acquired Myopathies: Clinical Applications and Perspectives
abstract	In the last years, magnetic resonance imaging (MRI) has become fundamental for the diagnosis and monitoring of myopathies given its ability to show the severity and distribution of pathology, to identify specific patterns of damage distribution and to properly interpret a number of genetic variants. The advances in MR techniques and post-processing software solutions have greatly expanded the potential to assess pathological changes in muscle diseases, and more specifically of myopathies; a number of features can be studied and quantified, ranging from composition, architecture, mechanical properties, perfusion, and function, leading to what is known as quantitative MRI (qMRI). Such techniques can effectively provide a variety of information beyond what can be seen and assessed by conventional MR imaging; their development and application in clinical practice can play an important role in the diagnostic process and in assessing disease course and treatment response. In this review, we briefly discuss the current role of muscle MRI in diagnosing muscle diseases and describe in detail the potential and perspectives of the application of advanced qMRI techniques in this field.
abstractGer	In the last years, magnetic resonance imaging (MRI) has become fundamental for the diagnosis and monitoring of myopathies given its ability to show the severity and distribution of pathology, to identify specific patterns of damage distribution and to properly interpret a number of genetic variants. The advances in MR techniques and post-processing software solutions have greatly expanded the potential to assess pathological changes in muscle diseases, and more specifically of myopathies; a number of features can be studied and quantified, ranging from composition, architecture, mechanical properties, perfusion, and function, leading to what is known as quantitative MRI (qMRI). Such techniques can effectively provide a variety of information beyond what can be seen and assessed by conventional MR imaging; their development and application in clinical practice can play an important role in the diagnostic process and in assessing disease course and treatment response. In this review, we briefly discuss the current role of muscle MRI in diagnosing muscle diseases and describe in detail the potential and perspectives of the application of advanced qMRI techniques in this field.
abstract_unstemmed	In the last years, magnetic resonance imaging (MRI) has become fundamental for the diagnosis and monitoring of myopathies given its ability to show the severity and distribution of pathology, to identify specific patterns of damage distribution and to properly interpret a number of genetic variants. The advances in MR techniques and post-processing software solutions have greatly expanded the potential to assess pathological changes in muscle diseases, and more specifically of myopathies; a number of features can be studied and quantified, ranging from composition, architecture, mechanical properties, perfusion, and function, leading to what is known as quantitative MRI (qMRI). Such techniques can effectively provide a variety of information beyond what can be seen and assessed by conventional MR imaging; their development and application in clinical practice can play an important role in the diagnostic process and in assessing disease course and treatment response. In this review, we briefly discuss the current role of muscle MRI in diagnosing muscle diseases and describe in detail the potential and perspectives of the application of advanced qMRI techniques in this field.
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title_short	Advances in Quantitative Imaging of Genetic and Acquired Myopathies: Clinical Applications and Perspectives
url	https://doi.org/10.3389/fneur.2019.00078 https://doaj.org/article/694100da1e6a4c0dafb9e81f18bd45a4 https://www.frontiersin.org/article/10.3389/fneur.2019.00078/full https://doaj.org/toc/1664-2295
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