Non-Coding RNAs and Hereditary Hemorrhagic Telangiectasia

Non-coding RNAs (ncRNAs) are functional ribonucleic acid (RNA) species that include microRNAs (miRs), a class of short non-coding RNAs (∼21–25 nucleotides), and long non-coding RNAs (lncRNAs) consisting of more than 200 nucleotides. They regulate gene expression post-transcriptionally and are involv...
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Autor*in:	Anthony Cannavicci [verfasserIn] Qiuwang Zhang [verfasserIn] Michael J. B. Kutryk [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2020

Schlagwörter:	non-coding RNAs microRNAs long non-coding RNAs hereditary hemorrhagic telangiectasia biomarkers endothelial cells

Übergeordnetes Werk:	In: Journal of Clinical Medicine - MDPI AG, 2013, 9(2020), 10, p 3333
Übergeordnetes Werk:	volume:9 ; year:2020 ; number:10, p 3333

Links:	Link aufrufen Link aufrufen Link aufrufen Journal toc

DOI / URN:	10.3390/jcm9103333

Katalog-ID:	DOAJ016765745

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author	Anthony Cannavicci
spellingShingle	Anthony Cannavicci misc non-coding RNAs misc microRNAs misc long non-coding RNAs misc hereditary hemorrhagic telangiectasia misc biomarkers misc endothelial cells misc Medicine misc R Non-Coding RNAs and Hereditary Hemorrhagic Telangiectasia
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topic_title	Non-Coding RNAs and Hereditary Hemorrhagic Telangiectasia non-coding RNAs microRNAs long non-coding RNAs hereditary hemorrhagic telangiectasia biomarkers endothelial cells
topic	misc non-coding RNAs misc microRNAs misc long non-coding RNAs misc hereditary hemorrhagic telangiectasia misc biomarkers misc endothelial cells misc Medicine misc R
topic_unstemmed	misc non-coding RNAs misc microRNAs misc long non-coding RNAs misc hereditary hemorrhagic telangiectasia misc biomarkers misc endothelial cells misc Medicine misc R
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title	Non-Coding RNAs and Hereditary Hemorrhagic Telangiectasia
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title_sort	non-coding rnas and hereditary hemorrhagic telangiectasia
title_auth	Non-Coding RNAs and Hereditary Hemorrhagic Telangiectasia
abstract	Non-coding RNAs (ncRNAs) are functional ribonucleic acid (RNA) species that include microRNAs (miRs), a class of short non-coding RNAs (∼21–25 nucleotides), and long non-coding RNAs (lncRNAs) consisting of more than 200 nucleotides. They regulate gene expression post-transcriptionally and are involved in a wide range of pathophysiological processes. Hereditary hemorrhagic telangiectasia (HHT) is a rare disorder inherited in an autosomal dominant fashion characterized by vascular dysplasia. Patients can develop life-threatening vascular malformations and experience severe hemorrhaging. Effective pharmacological therapies are limited. The study of ncRNAs in HHT is an emerging field with great promise. This review will explore the current literature on the involvement of ncRNAs in HHT as diagnostic and pathogenic factors.
abstractGer	Non-coding RNAs (ncRNAs) are functional ribonucleic acid (RNA) species that include microRNAs (miRs), a class of short non-coding RNAs (∼21–25 nucleotides), and long non-coding RNAs (lncRNAs) consisting of more than 200 nucleotides. They regulate gene expression post-transcriptionally and are involved in a wide range of pathophysiological processes. Hereditary hemorrhagic telangiectasia (HHT) is a rare disorder inherited in an autosomal dominant fashion characterized by vascular dysplasia. Patients can develop life-threatening vascular malformations and experience severe hemorrhaging. Effective pharmacological therapies are limited. The study of ncRNAs in HHT is an emerging field with great promise. This review will explore the current literature on the involvement of ncRNAs in HHT as diagnostic and pathogenic factors.
abstract_unstemmed	Non-coding RNAs (ncRNAs) are functional ribonucleic acid (RNA) species that include microRNAs (miRs), a class of short non-coding RNAs (∼21–25 nucleotides), and long non-coding RNAs (lncRNAs) consisting of more than 200 nucleotides. They regulate gene expression post-transcriptionally and are involved in a wide range of pathophysiological processes. Hereditary hemorrhagic telangiectasia (HHT) is a rare disorder inherited in an autosomal dominant fashion characterized by vascular dysplasia. Patients can develop life-threatening vascular malformations and experience severe hemorrhaging. Effective pharmacological therapies are limited. The study of ncRNAs in HHT is an emerging field with great promise. This review will explore the current literature on the involvement of ncRNAs in HHT as diagnostic and pathogenic factors.
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title_short	Non-Coding RNAs and Hereditary Hemorrhagic Telangiectasia
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