Prevalence and Diversity of Hepatitis Virus Markers among Patients with Acute Febrile Jaundice in Chad

Only a minority of the patients with acute febrile jaundice evaluated through the Yellow Fever surveillance program were found positive for antibodies against Yellow Fever Virus (YFV). In order to characterize patients with acute febrile jaundice negative for YFV, we collected 255 sera between Janua...
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Autor*in:	Fissou Henry Yandai [verfasserIn] Kuan Abdoulaye Traore [verfasserIn] Ali Mahamat Moussa [verfasserIn] Bruno Lalidia Ouoba [verfasserIn] Jean Bienvenue Ouoba [verfasserIn] Mahamat Ali Bolti [verfasserIn] Mahamat Fayiz Abakar [verfasserIn] Mathieu Hota [verfasserIn] Kadidja Gamougam [verfasserIn] Bessimbaye Nadlao [verfasserIn] Jean-Claude Uwimbabazi [verfasserIn] Nadji Emmanuel Tao [verfasserIn] Bongo Nare Ngandolo [verfasserIn] Pierre Roques [verfasserIn] Nicolas Barro [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2021

Schlagwörter:	hepatitis virus Yellow Fever Virus Yellow Fever surveillance program Chad

Übergeordnetes Werk:	In: Microbiology Research - MDPI AG, 2019, 12(2021), 4, Seite 878-887
Übergeordnetes Werk:	volume:12 ; year:2021 ; number:4 ; pages:878-887

Links:	Link aufrufen Link aufrufen Link aufrufen Journal toc

DOI / URN:	10.3390/microbiolres12040064

Katalog-ID:	DOAJ016864638

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allfields	10.3390/microbiolres12040064 doi (DE-627)DOAJ016864638 (DE-599)DOAJ462730c998ba4572992bcf4aa2437a92 DE-627 ger DE-627 rakwb eng QR1-502 Fissou Henry Yandai verfasserin aut Prevalence and Diversity of Hepatitis Virus Markers among Patients with Acute Febrile Jaundice in Chad 2021 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Only a minority of the patients with acute febrile jaundice evaluated through the Yellow Fever surveillance program were found positive for antibodies against Yellow Fever Virus (YFV). In order to characterize patients with acute febrile jaundice negative for YFV, we collected 255 sera between January to December 2019. We screened for HBV antigens, and antibodies against HCV and HEV. The seroprevalences observed were 10.6% (27/255) for HBV, 2% (5/255) for HCV, 17.3% (44/255) for HEV IgG, 4.3% (11/255) for HEV IgM, and 12.5% (32/255) for both IgG and IgM HEV. Prevalence of HEV was significantly higher in females than males (<i<p</i< < 0.01). HEV IgG prevalence was highest in those 20–29 years old, but the highest incidence rate (IgM positive) was in children 0–9 years old. Exposure to HEV was higher in the Sahelian zone (55.8%, 95% CI: 40.97–70.66) than in the Sudanese zone (30.2%, 95% CI: 24.01–36.37, <i<p</i< = 0.003). The high prevalence rates and hepatitis virus diversity underline the challenge of routine clinical diagnosis in Chad’s Yellow Fever surveillance program. hepatitis virus Yellow Fever Virus Yellow Fever surveillance program Chad Microbiology Kuan Abdoulaye Traore verfasserin aut Ali Mahamat Moussa verfasserin aut Bruno Lalidia Ouoba verfasserin aut Jean Bienvenue Ouoba verfasserin aut Mahamat Ali Bolti verfasserin aut Mahamat Fayiz Abakar verfasserin aut Mathieu Hota verfasserin aut Kadidja Gamougam verfasserin aut Bessimbaye Nadlao verfasserin aut Jean-Claude Uwimbabazi verfasserin aut Nadji Emmanuel Tao verfasserin aut Bongo Nare Ngandolo verfasserin aut Pierre Roques verfasserin aut Nicolas Barro verfasserin aut In Microbiology Research MDPI AG, 2019 12(2021), 4, Seite 878-887 (DE-627)634382519 (DE-600)2571057-6 20367481 nnns volume:12 year:2021 number:4 pages:878-887 https://doi.org/10.3390/microbiolres12040064 kostenfrei https://doaj.org/article/462730c998ba4572992bcf4aa2437a92 kostenfrei https://www.mdpi.com/2036-7481/12/4/64 kostenfrei https://doaj.org/toc/2036-7481 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 12 2021 4 878-887
spelling	10.3390/microbiolres12040064 doi (DE-627)DOAJ016864638 (DE-599)DOAJ462730c998ba4572992bcf4aa2437a92 DE-627 ger DE-627 rakwb eng QR1-502 Fissou Henry Yandai verfasserin aut Prevalence and Diversity of Hepatitis Virus Markers among Patients with Acute Febrile Jaundice in Chad 2021 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Only a minority of the patients with acute febrile jaundice evaluated through the Yellow Fever surveillance program were found positive for antibodies against Yellow Fever Virus (YFV). In order to characterize patients with acute febrile jaundice negative for YFV, we collected 255 sera between January to December 2019. We screened for HBV antigens, and antibodies against HCV and HEV. The seroprevalences observed were 10.6% (27/255) for HBV, 2% (5/255) for HCV, 17.3% (44/255) for HEV IgG, 4.3% (11/255) for HEV IgM, and 12.5% (32/255) for both IgG and IgM HEV. Prevalence of HEV was significantly higher in females than males (<i<p</i< < 0.01). HEV IgG prevalence was highest in those 20–29 years old, but the highest incidence rate (IgM positive) was in children 0–9 years old. Exposure to HEV was higher in the Sahelian zone (55.8%, 95% CI: 40.97–70.66) than in the Sudanese zone (30.2%, 95% CI: 24.01–36.37, <i<p</i< = 0.003). The high prevalence rates and hepatitis virus diversity underline the challenge of routine clinical diagnosis in Chad’s Yellow Fever surveillance program. hepatitis virus Yellow Fever Virus Yellow Fever surveillance program Chad Microbiology Kuan Abdoulaye Traore verfasserin aut Ali Mahamat Moussa verfasserin aut Bruno Lalidia Ouoba verfasserin aut Jean Bienvenue Ouoba verfasserin aut Mahamat Ali Bolti verfasserin aut Mahamat Fayiz Abakar verfasserin aut Mathieu Hota verfasserin aut Kadidja Gamougam verfasserin aut Bessimbaye Nadlao verfasserin aut Jean-Claude Uwimbabazi verfasserin aut Nadji Emmanuel Tao verfasserin aut Bongo Nare Ngandolo verfasserin aut Pierre Roques verfasserin aut Nicolas Barro verfasserin aut In Microbiology Research MDPI AG, 2019 12(2021), 4, Seite 878-887 (DE-627)634382519 (DE-600)2571057-6 20367481 nnns volume:12 year:2021 number:4 pages:878-887 https://doi.org/10.3390/microbiolres12040064 kostenfrei https://doaj.org/article/462730c998ba4572992bcf4aa2437a92 kostenfrei https://www.mdpi.com/2036-7481/12/4/64 kostenfrei https://doaj.org/toc/2036-7481 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 12 2021 4 878-887
allfields_unstemmed	10.3390/microbiolres12040064 doi (DE-627)DOAJ016864638 (DE-599)DOAJ462730c998ba4572992bcf4aa2437a92 DE-627 ger DE-627 rakwb eng QR1-502 Fissou Henry Yandai verfasserin aut Prevalence and Diversity of Hepatitis Virus Markers among Patients with Acute Febrile Jaundice in Chad 2021 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Only a minority of the patients with acute febrile jaundice evaluated through the Yellow Fever surveillance program were found positive for antibodies against Yellow Fever Virus (YFV). In order to characterize patients with acute febrile jaundice negative for YFV, we collected 255 sera between January to December 2019. We screened for HBV antigens, and antibodies against HCV and HEV. The seroprevalences observed were 10.6% (27/255) for HBV, 2% (5/255) for HCV, 17.3% (44/255) for HEV IgG, 4.3% (11/255) for HEV IgM, and 12.5% (32/255) for both IgG and IgM HEV. Prevalence of HEV was significantly higher in females than males (<i<p</i< < 0.01). HEV IgG prevalence was highest in those 20–29 years old, but the highest incidence rate (IgM positive) was in children 0–9 years old. Exposure to HEV was higher in the Sahelian zone (55.8%, 95% CI: 40.97–70.66) than in the Sudanese zone (30.2%, 95% CI: 24.01–36.37, <i<p</i< = 0.003). The high prevalence rates and hepatitis virus diversity underline the challenge of routine clinical diagnosis in Chad’s Yellow Fever surveillance program. hepatitis virus Yellow Fever Virus Yellow Fever surveillance program Chad Microbiology Kuan Abdoulaye Traore verfasserin aut Ali Mahamat Moussa verfasserin aut Bruno Lalidia Ouoba verfasserin aut Jean Bienvenue Ouoba verfasserin aut Mahamat Ali Bolti verfasserin aut Mahamat Fayiz Abakar verfasserin aut Mathieu Hota verfasserin aut Kadidja Gamougam verfasserin aut Bessimbaye Nadlao verfasserin aut Jean-Claude Uwimbabazi verfasserin aut Nadji Emmanuel Tao verfasserin aut Bongo Nare Ngandolo verfasserin aut Pierre Roques verfasserin aut Nicolas Barro verfasserin aut In Microbiology Research MDPI AG, 2019 12(2021), 4, Seite 878-887 (DE-627)634382519 (DE-600)2571057-6 20367481 nnns volume:12 year:2021 number:4 pages:878-887 https://doi.org/10.3390/microbiolres12040064 kostenfrei https://doaj.org/article/462730c998ba4572992bcf4aa2437a92 kostenfrei https://www.mdpi.com/2036-7481/12/4/64 kostenfrei https://doaj.org/toc/2036-7481 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 12 2021 4 878-887
allfieldsGer	10.3390/microbiolres12040064 doi (DE-627)DOAJ016864638 (DE-599)DOAJ462730c998ba4572992bcf4aa2437a92 DE-627 ger DE-627 rakwb eng QR1-502 Fissou Henry Yandai verfasserin aut Prevalence and Diversity of Hepatitis Virus Markers among Patients with Acute Febrile Jaundice in Chad 2021 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Only a minority of the patients with acute febrile jaundice evaluated through the Yellow Fever surveillance program were found positive for antibodies against Yellow Fever Virus (YFV). In order to characterize patients with acute febrile jaundice negative for YFV, we collected 255 sera between January to December 2019. We screened for HBV antigens, and antibodies against HCV and HEV. The seroprevalences observed were 10.6% (27/255) for HBV, 2% (5/255) for HCV, 17.3% (44/255) for HEV IgG, 4.3% (11/255) for HEV IgM, and 12.5% (32/255) for both IgG and IgM HEV. Prevalence of HEV was significantly higher in females than males (<i<p</i< < 0.01). HEV IgG prevalence was highest in those 20–29 years old, but the highest incidence rate (IgM positive) was in children 0–9 years old. Exposure to HEV was higher in the Sahelian zone (55.8%, 95% CI: 40.97–70.66) than in the Sudanese zone (30.2%, 95% CI: 24.01–36.37, <i<p</i< = 0.003). The high prevalence rates and hepatitis virus diversity underline the challenge of routine clinical diagnosis in Chad’s Yellow Fever surveillance program. hepatitis virus Yellow Fever Virus Yellow Fever surveillance program Chad Microbiology Kuan Abdoulaye Traore verfasserin aut Ali Mahamat Moussa verfasserin aut Bruno Lalidia Ouoba verfasserin aut Jean Bienvenue Ouoba verfasserin aut Mahamat Ali Bolti verfasserin aut Mahamat Fayiz Abakar verfasserin aut Mathieu Hota verfasserin aut Kadidja Gamougam verfasserin aut Bessimbaye Nadlao verfasserin aut Jean-Claude Uwimbabazi verfasserin aut Nadji Emmanuel Tao verfasserin aut Bongo Nare Ngandolo verfasserin aut Pierre Roques verfasserin aut Nicolas Barro verfasserin aut In Microbiology Research MDPI AG, 2019 12(2021), 4, Seite 878-887 (DE-627)634382519 (DE-600)2571057-6 20367481 nnns volume:12 year:2021 number:4 pages:878-887 https://doi.org/10.3390/microbiolres12040064 kostenfrei https://doaj.org/article/462730c998ba4572992bcf4aa2437a92 kostenfrei https://www.mdpi.com/2036-7481/12/4/64 kostenfrei https://doaj.org/toc/2036-7481 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 12 2021 4 878-887
allfieldsSound	10.3390/microbiolres12040064 doi (DE-627)DOAJ016864638 (DE-599)DOAJ462730c998ba4572992bcf4aa2437a92 DE-627 ger DE-627 rakwb eng QR1-502 Fissou Henry Yandai verfasserin aut Prevalence and Diversity of Hepatitis Virus Markers among Patients with Acute Febrile Jaundice in Chad 2021 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Only a minority of the patients with acute febrile jaundice evaluated through the Yellow Fever surveillance program were found positive for antibodies against Yellow Fever Virus (YFV). In order to characterize patients with acute febrile jaundice negative for YFV, we collected 255 sera between January to December 2019. We screened for HBV antigens, and antibodies against HCV and HEV. The seroprevalences observed were 10.6% (27/255) for HBV, 2% (5/255) for HCV, 17.3% (44/255) for HEV IgG, 4.3% (11/255) for HEV IgM, and 12.5% (32/255) for both IgG and IgM HEV. Prevalence of HEV was significantly higher in females than males (<i<p</i< < 0.01). HEV IgG prevalence was highest in those 20–29 years old, but the highest incidence rate (IgM positive) was in children 0–9 years old. Exposure to HEV was higher in the Sahelian zone (55.8%, 95% CI: 40.97–70.66) than in the Sudanese zone (30.2%, 95% CI: 24.01–36.37, <i<p</i< = 0.003). The high prevalence rates and hepatitis virus diversity underline the challenge of routine clinical diagnosis in Chad’s Yellow Fever surveillance program. hepatitis virus Yellow Fever Virus Yellow Fever surveillance program Chad Microbiology Kuan Abdoulaye Traore verfasserin aut Ali Mahamat Moussa verfasserin aut Bruno Lalidia Ouoba verfasserin aut Jean Bienvenue Ouoba verfasserin aut Mahamat Ali Bolti verfasserin aut Mahamat Fayiz Abakar verfasserin aut Mathieu Hota verfasserin aut Kadidja Gamougam verfasserin aut Bessimbaye Nadlao verfasserin aut Jean-Claude Uwimbabazi verfasserin aut Nadji Emmanuel Tao verfasserin aut Bongo Nare Ngandolo verfasserin aut Pierre Roques verfasserin aut Nicolas Barro verfasserin aut In Microbiology Research MDPI AG, 2019 12(2021), 4, Seite 878-887 (DE-627)634382519 (DE-600)2571057-6 20367481 nnns volume:12 year:2021 number:4 pages:878-887 https://doi.org/10.3390/microbiolres12040064 kostenfrei https://doaj.org/article/462730c998ba4572992bcf4aa2437a92 kostenfrei https://www.mdpi.com/2036-7481/12/4/64 kostenfrei https://doaj.org/toc/2036-7481 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 12 2021 4 878-887
language	English
source	In Microbiology Research 12(2021), 4, Seite 878-887 volume:12 year:2021 number:4 pages:878-887
sourceStr	In Microbiology Research 12(2021), 4, Seite 878-887 volume:12 year:2021 number:4 pages:878-887
format_phy_str_mv	Article
institution	findex.gbv.de
topic_facet	hepatitis virus Yellow Fever Virus Yellow Fever surveillance program Chad Microbiology
isfreeaccess_bool	true
container_title	Microbiology Research
authorswithroles_txt_mv	Fissou Henry Yandai @@aut@@ Kuan Abdoulaye Traore @@aut@@ Ali Mahamat Moussa @@aut@@ Bruno Lalidia Ouoba @@aut@@ Jean Bienvenue Ouoba @@aut@@ Mahamat Ali Bolti @@aut@@ Mahamat Fayiz Abakar @@aut@@ Mathieu Hota @@aut@@ Kadidja Gamougam @@aut@@ Bessimbaye Nadlao @@aut@@ Jean-Claude Uwimbabazi @@aut@@ Nadji Emmanuel Tao @@aut@@ Bongo Nare Ngandolo @@aut@@ Pierre Roques @@aut@@ Nicolas Barro @@aut@@
publishDateDaySort_date	2021-01-01T00:00:00Z
hierarchy_top_id	634382519
id	DOAJ016864638
language_de	englisch
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callnumber-first	Q - Science
author	Fissou Henry Yandai
spellingShingle	Fissou Henry Yandai misc QR1-502 misc hepatitis virus misc Yellow Fever Virus misc Yellow Fever surveillance program misc Chad misc Microbiology Prevalence and Diversity of Hepatitis Virus Markers among Patients with Acute Febrile Jaundice in Chad
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topic_title	QR1-502 Prevalence and Diversity of Hepatitis Virus Markers among Patients with Acute Febrile Jaundice in Chad hepatitis virus Yellow Fever Virus Yellow Fever surveillance program Chad
topic	misc QR1-502 misc hepatitis virus misc Yellow Fever Virus misc Yellow Fever surveillance program misc Chad misc Microbiology
topic_unstemmed	misc QR1-502 misc hepatitis virus misc Yellow Fever Virus misc Yellow Fever surveillance program misc Chad misc Microbiology
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title	Prevalence and Diversity of Hepatitis Virus Markers among Patients with Acute Febrile Jaundice in Chad
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title_full	Prevalence and Diversity of Hepatitis Virus Markers among Patients with Acute Febrile Jaundice in Chad
author_sort	Fissou Henry Yandai
journal	Microbiology Research
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author_browse	Fissou Henry Yandai Kuan Abdoulaye Traore Ali Mahamat Moussa Bruno Lalidia Ouoba Jean Bienvenue Ouoba Mahamat Ali Bolti Mahamat Fayiz Abakar Mathieu Hota Kadidja Gamougam Bessimbaye Nadlao Jean-Claude Uwimbabazi Nadji Emmanuel Tao Bongo Nare Ngandolo Pierre Roques Nicolas Barro
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title_sort	prevalence and diversity of hepatitis virus markers among patients with acute febrile jaundice in chad
callnumber	QR1-502
title_auth	Prevalence and Diversity of Hepatitis Virus Markers among Patients with Acute Febrile Jaundice in Chad
abstract	Only a minority of the patients with acute febrile jaundice evaluated through the Yellow Fever surveillance program were found positive for antibodies against Yellow Fever Virus (YFV). In order to characterize patients with acute febrile jaundice negative for YFV, we collected 255 sera between January to December 2019. We screened for HBV antigens, and antibodies against HCV and HEV. The seroprevalences observed were 10.6% (27/255) for HBV, 2% (5/255) for HCV, 17.3% (44/255) for HEV IgG, 4.3% (11/255) for HEV IgM, and 12.5% (32/255) for both IgG and IgM HEV. Prevalence of HEV was significantly higher in females than males (<i<p</i< < 0.01). HEV IgG prevalence was highest in those 20–29 years old, but the highest incidence rate (IgM positive) was in children 0–9 years old. Exposure to HEV was higher in the Sahelian zone (55.8%, 95% CI: 40.97–70.66) than in the Sudanese zone (30.2%, 95% CI: 24.01–36.37, <i<p</i< = 0.003). The high prevalence rates and hepatitis virus diversity underline the challenge of routine clinical diagnosis in Chad’s Yellow Fever surveillance program.
abstractGer	Only a minority of the patients with acute febrile jaundice evaluated through the Yellow Fever surveillance program were found positive for antibodies against Yellow Fever Virus (YFV). In order to characterize patients with acute febrile jaundice negative for YFV, we collected 255 sera between January to December 2019. We screened for HBV antigens, and antibodies against HCV and HEV. The seroprevalences observed were 10.6% (27/255) for HBV, 2% (5/255) for HCV, 17.3% (44/255) for HEV IgG, 4.3% (11/255) for HEV IgM, and 12.5% (32/255) for both IgG and IgM HEV. Prevalence of HEV was significantly higher in females than males (<i<p</i< < 0.01). HEV IgG prevalence was highest in those 20–29 years old, but the highest incidence rate (IgM positive) was in children 0–9 years old. Exposure to HEV was higher in the Sahelian zone (55.8%, 95% CI: 40.97–70.66) than in the Sudanese zone (30.2%, 95% CI: 24.01–36.37, <i<p</i< = 0.003). The high prevalence rates and hepatitis virus diversity underline the challenge of routine clinical diagnosis in Chad’s Yellow Fever surveillance program.
abstract_unstemmed	Only a minority of the patients with acute febrile jaundice evaluated through the Yellow Fever surveillance program were found positive for antibodies against Yellow Fever Virus (YFV). In order to characterize patients with acute febrile jaundice negative for YFV, we collected 255 sera between January to December 2019. We screened for HBV antigens, and antibodies against HCV and HEV. The seroprevalences observed were 10.6% (27/255) for HBV, 2% (5/255) for HCV, 17.3% (44/255) for HEV IgG, 4.3% (11/255) for HEV IgM, and 12.5% (32/255) for both IgG and IgM HEV. Prevalence of HEV was significantly higher in females than males (<i<p</i< < 0.01). HEV IgG prevalence was highest in those 20–29 years old, but the highest incidence rate (IgM positive) was in children 0–9 years old. Exposure to HEV was higher in the Sahelian zone (55.8%, 95% CI: 40.97–70.66) than in the Sudanese zone (30.2%, 95% CI: 24.01–36.37, <i<p</i< = 0.003). The high prevalence rates and hepatitis virus diversity underline the challenge of routine clinical diagnosis in Chad’s Yellow Fever surveillance program.
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title_short	Prevalence and Diversity of Hepatitis Virus Markers among Patients with Acute Febrile Jaundice in Chad
url	https://doi.org/10.3390/microbiolres12040064 https://doaj.org/article/462730c998ba4572992bcf4aa2437a92 https://www.mdpi.com/2036-7481/12/4/64 https://doaj.org/toc/2036-7481
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author2	Kuan Abdoulaye Traore Ali Mahamat Moussa Bruno Lalidia Ouoba Jean Bienvenue Ouoba Mahamat Ali Bolti Mahamat Fayiz Abakar Mathieu Hota Kadidja Gamougam Bessimbaye Nadlao Jean-Claude Uwimbabazi Nadji Emmanuel Tao Bongo Nare Ngandolo Pierre Roques Nicolas Barro
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up_date	2024-07-03T23:20:01.947Z
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