Usefulness of pelvic ultrasonography for the diagnosis of central precocious puberty in girls

PurposeIt is difficult to differentiate between central precocious puberty (CPP) and premature thelarche (PT) in girls. The aim of this study was to investigate the diagnostic usefulness of pelvic ultrasonography to distinguish between CPP and PT in girls with early breast development.MethodsThis st...
Ausführliche Beschreibung

Gespeichert in:

Autor*in:	Jung Yu [verfasserIn] Ha Young Shin [verfasserIn] Sun Hee Lee [verfasserIn] You Sung Kim [verfasserIn] Jae Hyun Kim [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2015

Schlagwörter:	Precocious puberty Diagnosis Pelvis Ultrasonography Girls

Übergeordnetes Werk:	In: Korean Journal of Pediatrics - Korean Pediatric Society, 2013, 58(2015), 8, Seite 294-300
Übergeordnetes Werk:	volume:58 ; year:2015 ; number:8 ; pages:294-300

Links:	Link aufrufen Link aufrufen Link aufrufen Journal toc Journal toc

DOI / URN:	10.3345/kjp.2015.58.8.294

Katalog-ID:	DOAJ017287545

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520			\|a PurposeIt is difficult to differentiate between central precocious puberty (CPP) and premature thelarche (PT) in girls. The aim of this study was to investigate the diagnostic usefulness of pelvic ultrasonography to distinguish between CPP and PT in girls with early breast development.MethodsThis study included girls with early breast development who visited the clinic between January 2012 and December 2013. Clinical, laboratory, and pelvic ultrasonographic data were evaluated. CPP and PT were confirmed using the gonadotropin-releasing hormone stimulation test.ResultsA total of 248 girls aged 7-8 years were included, among whom 186 (75.0%) had CPP and 62 (25.0%) had PT. The uterine length, transverse diameter, fundus, volume, and cross-sectional area were significantly larger in the CPP group (uterine length, 2.45±0.50 cm vs. 2.63±0.49 cm, P=0.015; uterine volume, 0.95±0.62 cm3 vs. 1.35±0.76 cm3, P<0.001). However, there were no differences in the fundus/cervix ratio and ovarian measurements. In receiver operating characteristic analysis, a uterine volume of at least 1.07 cm3 was the most predictive parameter for CPP with an area under the curve of 0.670 (95% confidence interval, 0.593-0.747).ConclusionUterine measurements by pelvic ultrasonography in girls with early pubertal development were significantly larger in the CPP group. However, the diagnostic value of ultrasonographic parameters was not high because of a considerable overlap of values between the two groups. Therefore, pelvic ultrasonography in combination with clinical and laboratory tests may be useful to distinguish between CPP and PT in girls.
650		4	\|a Precocious puberty
650		4	\|a Diagnosis
650		4	\|a Pelvis
650		4	\|a Ultrasonography
650		4	\|a Girls
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700	0		\|a Sun Hee Lee \|e verfasserin \|4 aut
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700	0		\|a Jae Hyun Kim \|e verfasserin \|4 aut
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allfields	10.3345/kjp.2015.58.8.294 doi (DE-627)DOAJ017287545 (DE-599)DOAJ3eecabb50cfc442c9acf705ca28ace67 DE-627 ger DE-627 rakwb eng RJ1-570 Jung Yu verfasserin aut Usefulness of pelvic ultrasonography for the diagnosis of central precocious puberty in girls 2015 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier PurposeIt is difficult to differentiate between central precocious puberty (CPP) and premature thelarche (PT) in girls. The aim of this study was to investigate the diagnostic usefulness of pelvic ultrasonography to distinguish between CPP and PT in girls with early breast development.MethodsThis study included girls with early breast development who visited the clinic between January 2012 and December 2013. Clinical, laboratory, and pelvic ultrasonographic data were evaluated. CPP and PT were confirmed using the gonadotropin-releasing hormone stimulation test.ResultsA total of 248 girls aged 7-8 years were included, among whom 186 (75.0%) had CPP and 62 (25.0%) had PT. The uterine length, transverse diameter, fundus, volume, and cross-sectional area were significantly larger in the CPP group (uterine length, 2.45±0.50 cm vs. 2.63±0.49 cm, P=0.015; uterine volume, 0.95±0.62 cm3 vs. 1.35±0.76 cm3, P<0.001). However, there were no differences in the fundus/cervix ratio and ovarian measurements. In receiver operating characteristic analysis, a uterine volume of at least 1.07 cm3 was the most predictive parameter for CPP with an area under the curve of 0.670 (95% confidence interval, 0.593-0.747).ConclusionUterine measurements by pelvic ultrasonography in girls with early pubertal development were significantly larger in the CPP group. However, the diagnostic value of ultrasonographic parameters was not high because of a considerable overlap of values between the two groups. Therefore, pelvic ultrasonography in combination with clinical and laboratory tests may be useful to distinguish between CPP and PT in girls. Precocious puberty Diagnosis Pelvis Ultrasonography Girls Pediatrics Ha Young Shin verfasserin aut Sun Hee Lee verfasserin aut You Sung Kim verfasserin aut Jae Hyun Kim verfasserin aut In Korean Journal of Pediatrics Korean Pediatric Society, 2013 58(2015), 8, Seite 294-300 (DE-627)647303264 (DE-600)2594966-4 20927258 nnns volume:58 year:2015 number:8 pages:294-300 https://doi.org/10.3345/kjp.2015.58.8.294 kostenfrei https://doaj.org/article/3eecabb50cfc442c9acf705ca28ace67 kostenfrei http://kjp.or.kr/upload/pdf/kjped-58-294.pdf kostenfrei https://doaj.org/toc/1738-1061 Journal toc kostenfrei https://doaj.org/toc/2092-7258 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 58 2015 8 294-300
spelling	10.3345/kjp.2015.58.8.294 doi (DE-627)DOAJ017287545 (DE-599)DOAJ3eecabb50cfc442c9acf705ca28ace67 DE-627 ger DE-627 rakwb eng RJ1-570 Jung Yu verfasserin aut Usefulness of pelvic ultrasonography for the diagnosis of central precocious puberty in girls 2015 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier PurposeIt is difficult to differentiate between central precocious puberty (CPP) and premature thelarche (PT) in girls. The aim of this study was to investigate the diagnostic usefulness of pelvic ultrasonography to distinguish between CPP and PT in girls with early breast development.MethodsThis study included girls with early breast development who visited the clinic between January 2012 and December 2013. Clinical, laboratory, and pelvic ultrasonographic data were evaluated. CPP and PT were confirmed using the gonadotropin-releasing hormone stimulation test.ResultsA total of 248 girls aged 7-8 years were included, among whom 186 (75.0%) had CPP and 62 (25.0%) had PT. The uterine length, transverse diameter, fundus, volume, and cross-sectional area were significantly larger in the CPP group (uterine length, 2.45±0.50 cm vs. 2.63±0.49 cm, P=0.015; uterine volume, 0.95±0.62 cm3 vs. 1.35±0.76 cm3, P<0.001). However, there were no differences in the fundus/cervix ratio and ovarian measurements. In receiver operating characteristic analysis, a uterine volume of at least 1.07 cm3 was the most predictive parameter for CPP with an area under the curve of 0.670 (95% confidence interval, 0.593-0.747).ConclusionUterine measurements by pelvic ultrasonography in girls with early pubertal development were significantly larger in the CPP group. However, the diagnostic value of ultrasonographic parameters was not high because of a considerable overlap of values between the two groups. Therefore, pelvic ultrasonography in combination with clinical and laboratory tests may be useful to distinguish between CPP and PT in girls. Precocious puberty Diagnosis Pelvis Ultrasonography Girls Pediatrics Ha Young Shin verfasserin aut Sun Hee Lee verfasserin aut You Sung Kim verfasserin aut Jae Hyun Kim verfasserin aut In Korean Journal of Pediatrics Korean Pediatric Society, 2013 58(2015), 8, Seite 294-300 (DE-627)647303264 (DE-600)2594966-4 20927258 nnns volume:58 year:2015 number:8 pages:294-300 https://doi.org/10.3345/kjp.2015.58.8.294 kostenfrei https://doaj.org/article/3eecabb50cfc442c9acf705ca28ace67 kostenfrei http://kjp.or.kr/upload/pdf/kjped-58-294.pdf kostenfrei https://doaj.org/toc/1738-1061 Journal toc kostenfrei https://doaj.org/toc/2092-7258 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 58 2015 8 294-300
allfields_unstemmed	10.3345/kjp.2015.58.8.294 doi (DE-627)DOAJ017287545 (DE-599)DOAJ3eecabb50cfc442c9acf705ca28ace67 DE-627 ger DE-627 rakwb eng RJ1-570 Jung Yu verfasserin aut Usefulness of pelvic ultrasonography for the diagnosis of central precocious puberty in girls 2015 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier PurposeIt is difficult to differentiate between central precocious puberty (CPP) and premature thelarche (PT) in girls. The aim of this study was to investigate the diagnostic usefulness of pelvic ultrasonography to distinguish between CPP and PT in girls with early breast development.MethodsThis study included girls with early breast development who visited the clinic between January 2012 and December 2013. Clinical, laboratory, and pelvic ultrasonographic data were evaluated. CPP and PT were confirmed using the gonadotropin-releasing hormone stimulation test.ResultsA total of 248 girls aged 7-8 years were included, among whom 186 (75.0%) had CPP and 62 (25.0%) had PT. The uterine length, transverse diameter, fundus, volume, and cross-sectional area were significantly larger in the CPP group (uterine length, 2.45±0.50 cm vs. 2.63±0.49 cm, P=0.015; uterine volume, 0.95±0.62 cm3 vs. 1.35±0.76 cm3, P<0.001). However, there were no differences in the fundus/cervix ratio and ovarian measurements. In receiver operating characteristic analysis, a uterine volume of at least 1.07 cm3 was the most predictive parameter for CPP with an area under the curve of 0.670 (95% confidence interval, 0.593-0.747).ConclusionUterine measurements by pelvic ultrasonography in girls with early pubertal development were significantly larger in the CPP group. However, the diagnostic value of ultrasonographic parameters was not high because of a considerable overlap of values between the two groups. Therefore, pelvic ultrasonography in combination with clinical and laboratory tests may be useful to distinguish between CPP and PT in girls. Precocious puberty Diagnosis Pelvis Ultrasonography Girls Pediatrics Ha Young Shin verfasserin aut Sun Hee Lee verfasserin aut You Sung Kim verfasserin aut Jae Hyun Kim verfasserin aut In Korean Journal of Pediatrics Korean Pediatric Society, 2013 58(2015), 8, Seite 294-300 (DE-627)647303264 (DE-600)2594966-4 20927258 nnns volume:58 year:2015 number:8 pages:294-300 https://doi.org/10.3345/kjp.2015.58.8.294 kostenfrei https://doaj.org/article/3eecabb50cfc442c9acf705ca28ace67 kostenfrei http://kjp.or.kr/upload/pdf/kjped-58-294.pdf kostenfrei https://doaj.org/toc/1738-1061 Journal toc kostenfrei https://doaj.org/toc/2092-7258 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 58 2015 8 294-300
allfieldsGer	10.3345/kjp.2015.58.8.294 doi (DE-627)DOAJ017287545 (DE-599)DOAJ3eecabb50cfc442c9acf705ca28ace67 DE-627 ger DE-627 rakwb eng RJ1-570 Jung Yu verfasserin aut Usefulness of pelvic ultrasonography for the diagnosis of central precocious puberty in girls 2015 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier PurposeIt is difficult to differentiate between central precocious puberty (CPP) and premature thelarche (PT) in girls. The aim of this study was to investigate the diagnostic usefulness of pelvic ultrasonography to distinguish between CPP and PT in girls with early breast development.MethodsThis study included girls with early breast development who visited the clinic between January 2012 and December 2013. Clinical, laboratory, and pelvic ultrasonographic data were evaluated. CPP and PT were confirmed using the gonadotropin-releasing hormone stimulation test.ResultsA total of 248 girls aged 7-8 years were included, among whom 186 (75.0%) had CPP and 62 (25.0%) had PT. The uterine length, transverse diameter, fundus, volume, and cross-sectional area were significantly larger in the CPP group (uterine length, 2.45±0.50 cm vs. 2.63±0.49 cm, P=0.015; uterine volume, 0.95±0.62 cm3 vs. 1.35±0.76 cm3, P<0.001). However, there were no differences in the fundus/cervix ratio and ovarian measurements. In receiver operating characteristic analysis, a uterine volume of at least 1.07 cm3 was the most predictive parameter for CPP with an area under the curve of 0.670 (95% confidence interval, 0.593-0.747).ConclusionUterine measurements by pelvic ultrasonography in girls with early pubertal development were significantly larger in the CPP group. However, the diagnostic value of ultrasonographic parameters was not high because of a considerable overlap of values between the two groups. Therefore, pelvic ultrasonography in combination with clinical and laboratory tests may be useful to distinguish between CPP and PT in girls. Precocious puberty Diagnosis Pelvis Ultrasonography Girls Pediatrics Ha Young Shin verfasserin aut Sun Hee Lee verfasserin aut You Sung Kim verfasserin aut Jae Hyun Kim verfasserin aut In Korean Journal of Pediatrics Korean Pediatric Society, 2013 58(2015), 8, Seite 294-300 (DE-627)647303264 (DE-600)2594966-4 20927258 nnns volume:58 year:2015 number:8 pages:294-300 https://doi.org/10.3345/kjp.2015.58.8.294 kostenfrei https://doaj.org/article/3eecabb50cfc442c9acf705ca28ace67 kostenfrei http://kjp.or.kr/upload/pdf/kjped-58-294.pdf kostenfrei https://doaj.org/toc/1738-1061 Journal toc kostenfrei https://doaj.org/toc/2092-7258 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 58 2015 8 294-300
allfieldsSound	10.3345/kjp.2015.58.8.294 doi (DE-627)DOAJ017287545 (DE-599)DOAJ3eecabb50cfc442c9acf705ca28ace67 DE-627 ger DE-627 rakwb eng RJ1-570 Jung Yu verfasserin aut Usefulness of pelvic ultrasonography for the diagnosis of central precocious puberty in girls 2015 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier PurposeIt is difficult to differentiate between central precocious puberty (CPP) and premature thelarche (PT) in girls. The aim of this study was to investigate the diagnostic usefulness of pelvic ultrasonography to distinguish between CPP and PT in girls with early breast development.MethodsThis study included girls with early breast development who visited the clinic between January 2012 and December 2013. Clinical, laboratory, and pelvic ultrasonographic data were evaluated. CPP and PT were confirmed using the gonadotropin-releasing hormone stimulation test.ResultsA total of 248 girls aged 7-8 years were included, among whom 186 (75.0%) had CPP and 62 (25.0%) had PT. The uterine length, transverse diameter, fundus, volume, and cross-sectional area were significantly larger in the CPP group (uterine length, 2.45±0.50 cm vs. 2.63±0.49 cm, P=0.015; uterine volume, 0.95±0.62 cm3 vs. 1.35±0.76 cm3, P<0.001). However, there were no differences in the fundus/cervix ratio and ovarian measurements. In receiver operating characteristic analysis, a uterine volume of at least 1.07 cm3 was the most predictive parameter for CPP with an area under the curve of 0.670 (95% confidence interval, 0.593-0.747).ConclusionUterine measurements by pelvic ultrasonography in girls with early pubertal development were significantly larger in the CPP group. However, the diagnostic value of ultrasonographic parameters was not high because of a considerable overlap of values between the two groups. Therefore, pelvic ultrasonography in combination with clinical and laboratory tests may be useful to distinguish between CPP and PT in girls. Precocious puberty Diagnosis Pelvis Ultrasonography Girls Pediatrics Ha Young Shin verfasserin aut Sun Hee Lee verfasserin aut You Sung Kim verfasserin aut Jae Hyun Kim verfasserin aut In Korean Journal of Pediatrics Korean Pediatric Society, 2013 58(2015), 8, Seite 294-300 (DE-627)647303264 (DE-600)2594966-4 20927258 nnns volume:58 year:2015 number:8 pages:294-300 https://doi.org/10.3345/kjp.2015.58.8.294 kostenfrei https://doaj.org/article/3eecabb50cfc442c9acf705ca28ace67 kostenfrei http://kjp.or.kr/upload/pdf/kjped-58-294.pdf kostenfrei https://doaj.org/toc/1738-1061 Journal toc kostenfrei https://doaj.org/toc/2092-7258 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 58 2015 8 294-300
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The aim of this study was to investigate the diagnostic usefulness of pelvic ultrasonography to distinguish between CPP and PT in girls with early breast development.MethodsThis study included girls with early breast development who visited the clinic between January 2012 and December 2013. Clinical, laboratory, and pelvic ultrasonographic data were evaluated. CPP and PT were confirmed using the gonadotropin-releasing hormone stimulation test.ResultsA total of 248 girls aged 7-8 years were included, among whom 186 (75.0%) had CPP and 62 (25.0%) had PT. The uterine length, transverse diameter, fundus, volume, and cross-sectional area were significantly larger in the CPP group (uterine length, 2.45±0.50 cm vs. 2.63±0.49 cm, P=0.015; uterine volume, 0.95±0.62 cm3 vs. 1.35±0.76 cm3, P<0.001). However, there were no differences in the fundus/cervix ratio and ovarian measurements. In receiver operating characteristic analysis, a uterine volume of at least 1.07 cm3 was the most predictive parameter for CPP with an area under the curve of 0.670 (95% confidence interval, 0.593-0.747).ConclusionUterine measurements by pelvic ultrasonography in girls with early pubertal development were significantly larger in the CPP group. However, the diagnostic value of ultrasonographic parameters was not high because of a considerable overlap of values between the two groups. 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callnumber-first	R - Medicine
author	Jung Yu
spellingShingle	Jung Yu misc RJ1-570 misc Precocious puberty misc Diagnosis misc Pelvis misc Ultrasonography misc Girls misc Pediatrics Usefulness of pelvic ultrasonography for the diagnosis of central precocious puberty in girls
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topic_title	RJ1-570 Usefulness of pelvic ultrasonography for the diagnosis of central precocious puberty in girls Precocious puberty Diagnosis Pelvis Ultrasonography Girls
topic	misc RJ1-570 misc Precocious puberty misc Diagnosis misc Pelvis misc Ultrasonography misc Girls misc Pediatrics
topic_unstemmed	misc RJ1-570 misc Precocious puberty misc Diagnosis misc Pelvis misc Ultrasonography misc Girls misc Pediatrics
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title	Usefulness of pelvic ultrasonography for the diagnosis of central precocious puberty in girls
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title_full	Usefulness of pelvic ultrasonography for the diagnosis of central precocious puberty in girls
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title_sort	usefulness of pelvic ultrasonography for the diagnosis of central precocious puberty in girls
callnumber	RJ1-570
title_auth	Usefulness of pelvic ultrasonography for the diagnosis of central precocious puberty in girls
abstract	PurposeIt is difficult to differentiate between central precocious puberty (CPP) and premature thelarche (PT) in girls. The aim of this study was to investigate the diagnostic usefulness of pelvic ultrasonography to distinguish between CPP and PT in girls with early breast development.MethodsThis study included girls with early breast development who visited the clinic between January 2012 and December 2013. Clinical, laboratory, and pelvic ultrasonographic data were evaluated. CPP and PT were confirmed using the gonadotropin-releasing hormone stimulation test.ResultsA total of 248 girls aged 7-8 years were included, among whom 186 (75.0%) had CPP and 62 (25.0%) had PT. The uterine length, transverse diameter, fundus, volume, and cross-sectional area were significantly larger in the CPP group (uterine length, 2.45±0.50 cm vs. 2.63±0.49 cm, P=0.015; uterine volume, 0.95±0.62 cm3 vs. 1.35±0.76 cm3, P<0.001). However, there were no differences in the fundus/cervix ratio and ovarian measurements. In receiver operating characteristic analysis, a uterine volume of at least 1.07 cm3 was the most predictive parameter for CPP with an area under the curve of 0.670 (95% confidence interval, 0.593-0.747).ConclusionUterine measurements by pelvic ultrasonography in girls with early pubertal development were significantly larger in the CPP group. However, the diagnostic value of ultrasonographic parameters was not high because of a considerable overlap of values between the two groups. Therefore, pelvic ultrasonography in combination with clinical and laboratory tests may be useful to distinguish between CPP and PT in girls.
abstractGer	PurposeIt is difficult to differentiate between central precocious puberty (CPP) and premature thelarche (PT) in girls. The aim of this study was to investigate the diagnostic usefulness of pelvic ultrasonography to distinguish between CPP and PT in girls with early breast development.MethodsThis study included girls with early breast development who visited the clinic between January 2012 and December 2013. Clinical, laboratory, and pelvic ultrasonographic data were evaluated. CPP and PT were confirmed using the gonadotropin-releasing hormone stimulation test.ResultsA total of 248 girls aged 7-8 years were included, among whom 186 (75.0%) had CPP and 62 (25.0%) had PT. The uterine length, transverse diameter, fundus, volume, and cross-sectional area were significantly larger in the CPP group (uterine length, 2.45±0.50 cm vs. 2.63±0.49 cm, P=0.015; uterine volume, 0.95±0.62 cm3 vs. 1.35±0.76 cm3, P<0.001). However, there were no differences in the fundus/cervix ratio and ovarian measurements. In receiver operating characteristic analysis, a uterine volume of at least 1.07 cm3 was the most predictive parameter for CPP with an area under the curve of 0.670 (95% confidence interval, 0.593-0.747).ConclusionUterine measurements by pelvic ultrasonography in girls with early pubertal development were significantly larger in the CPP group. However, the diagnostic value of ultrasonographic parameters was not high because of a considerable overlap of values between the two groups. Therefore, pelvic ultrasonography in combination with clinical and laboratory tests may be useful to distinguish between CPP and PT in girls.
abstract_unstemmed	PurposeIt is difficult to differentiate between central precocious puberty (CPP) and premature thelarche (PT) in girls. The aim of this study was to investigate the diagnostic usefulness of pelvic ultrasonography to distinguish between CPP and PT in girls with early breast development.MethodsThis study included girls with early breast development who visited the clinic between January 2012 and December 2013. Clinical, laboratory, and pelvic ultrasonographic data were evaluated. CPP and PT were confirmed using the gonadotropin-releasing hormone stimulation test.ResultsA total of 248 girls aged 7-8 years were included, among whom 186 (75.0%) had CPP and 62 (25.0%) had PT. The uterine length, transverse diameter, fundus, volume, and cross-sectional area were significantly larger in the CPP group (uterine length, 2.45±0.50 cm vs. 2.63±0.49 cm, P=0.015; uterine volume, 0.95±0.62 cm3 vs. 1.35±0.76 cm3, P<0.001). However, there were no differences in the fundus/cervix ratio and ovarian measurements. In receiver operating characteristic analysis, a uterine volume of at least 1.07 cm3 was the most predictive parameter for CPP with an area under the curve of 0.670 (95% confidence interval, 0.593-0.747).ConclusionUterine measurements by pelvic ultrasonography in girls with early pubertal development were significantly larger in the CPP group. However, the diagnostic value of ultrasonographic parameters was not high because of a considerable overlap of values between the two groups. Therefore, pelvic ultrasonography in combination with clinical and laboratory tests may be useful to distinguish between CPP and PT in girls.
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title_short	Usefulness of pelvic ultrasonography for the diagnosis of central precocious puberty in girls
url	https://doi.org/10.3345/kjp.2015.58.8.294 https://doaj.org/article/3eecabb50cfc442c9acf705ca28ace67 http://kjp.or.kr/upload/pdf/kjped-58-294.pdf https://doaj.org/toc/1738-1061 https://doaj.org/toc/2092-7258
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In receiver operating characteristic analysis, a uterine volume of at least 1.07 cm3 was the most predictive parameter for CPP with an area under the curve of 0.670 (95% confidence interval, 0.593-0.747).ConclusionUterine measurements by pelvic ultrasonography in girls with early pubertal development were significantly larger in the CPP group. However, the diagnostic value of ultrasonographic parameters was not high because of a considerable overlap of values between the two groups. 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Usefulness of pelvic ultrasonography for the diagnosis of central precocious puberty in girls

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