Peripheral and central giant cell lesions: etiology, origin of giant cells, diagnosis and treatment

INTRODUCTION AND OBJECTIVE: The peripheral and central giant cell lesions (PGCL and CGCL) are a group of pathological entities with similar histopathological features and whose origin has not been fully elucidated. The former is reactive and the latter exhibits a non-neoplastic proliferative behavio...
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Gespeichert in:

Autor*in:	Rodrigo Gadelha Vasconcelos [verfasserIn] Marcelo Gadelha Vasconcelos [verfasserIn] Lélia Maria Guedes Queiroz [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2013

Schlagwörter:	lesão periférica de células gigantes lesão central de células gigantes gengiva maxila mandíbula

Übergeordnetes Werk:	In: Jornal Brasileiro de Patologia e Medicina Laboratorial - Sociedade Brasileira de Patologia Clínica, 2004, 49(2013), 6, Seite 446-452
Übergeordnetes Werk:	volume:49 ; year:2013 ; number:6 ; pages:446-452

Links:	Link aufrufen Link aufrufen Link aufrufen Journal toc

DOI / URN:	10.1590/S1676-24442013000600011

Katalog-ID:	DOAJ017515874

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allfieldsSound	10.1590/S1676-24442013000600011 doi (DE-627)DOAJ017515874 (DE-599)DOAJ4c6fad4ced364675b3714cdbeab4fe36 DE-627 ger DE-627 rakwb eng RB1-214 Rodrigo Gadelha Vasconcelos verfasserin aut Peripheral and central giant cell lesions: etiology, origin of giant cells, diagnosis and treatment 2013 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier INTRODUCTION AND OBJECTIVE: The peripheral and central giant cell lesions (PGCL and CGCL) are a group of pathological entities with similar histopathological features and whose origin has not been fully elucidated. The former is reactive and the latter exhibits a non-neoplastic proliferative behavior. This article aims to review the literature on peripheral giant cell lesions (PGCL) and central giant cell lesions (CGCL) by discussing the most important aspects pertaining to each of them. RESULTS: These lesions are found in different locations and show diverse clinical signs despite having the same histopathological features. The treatment consists in the surgical resection by different techniques depending on the type of the lesion and clinical conditions. In the case of CGCL, drug therapy may also be employed. CONCLUSION: Although there is no consensus in the literature, it is essential to know the etiology of these lesions as well as the exact origin of the giant cells. Due to their singular biological behavior, it is of utmost importance to establish a differential diagnosis between the two lesions and other processes that have similar clinical, radiological and histological characteristics, inasmuch as this procedure is essential to provide a suitable treatment and establish a prognosis. lesão periférica de células gigantes lesão central de células gigantes gengiva maxila mandíbula Pathology Marcelo Gadelha Vasconcelos verfasserin aut Lélia Maria Guedes Queiroz verfasserin aut In Jornal Brasileiro de Patologia e Medicina Laboratorial Sociedade Brasileira de Patologia Clínica, 2004 49(2013), 6, Seite 446-452 (DE-627)363752749 (DE-600)2105625-0 16784774 nnns volume:49 year:2013 number:6 pages:446-452 https://doi.org/10.1590/S1676-24442013000600011 kostenfrei https://doaj.org/article/4c6fad4ced364675b3714cdbeab4fe36 kostenfrei http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1676-24442013000600011&lng=en&tlng=en kostenfrei https://doaj.org/toc/1678-4774 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 49 2013 6 446-452
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callnumber-first	R - Medicine
author	Rodrigo Gadelha Vasconcelos
spellingShingle	Rodrigo Gadelha Vasconcelos misc RB1-214 misc lesão periférica de células gigantes misc lesão central de células gigantes misc gengiva misc maxila misc mandíbula misc Pathology Peripheral and central giant cell lesions: etiology, origin of giant cells, diagnosis and treatment
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topic_title	RB1-214 Peripheral and central giant cell lesions: etiology, origin of giant cells, diagnosis and treatment lesão periférica de células gigantes lesão central de células gigantes gengiva maxila mandíbula
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title	Peripheral and central giant cell lesions: etiology, origin of giant cells, diagnosis and treatment
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title_full	Peripheral and central giant cell lesions: etiology, origin of giant cells, diagnosis and treatment
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title_sort	peripheral and central giant cell lesions: etiology, origin of giant cells, diagnosis and treatment
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title_auth	Peripheral and central giant cell lesions: etiology, origin of giant cells, diagnosis and treatment
abstract	INTRODUCTION AND OBJECTIVE: The peripheral and central giant cell lesions (PGCL and CGCL) are a group of pathological entities with similar histopathological features and whose origin has not been fully elucidated. The former is reactive and the latter exhibits a non-neoplastic proliferative behavior. This article aims to review the literature on peripheral giant cell lesions (PGCL) and central giant cell lesions (CGCL) by discussing the most important aspects pertaining to each of them. RESULTS: These lesions are found in different locations and show diverse clinical signs despite having the same histopathological features. The treatment consists in the surgical resection by different techniques depending on the type of the lesion and clinical conditions. In the case of CGCL, drug therapy may also be employed. CONCLUSION: Although there is no consensus in the literature, it is essential to know the etiology of these lesions as well as the exact origin of the giant cells. Due to their singular biological behavior, it is of utmost importance to establish a differential diagnosis between the two lesions and other processes that have similar clinical, radiological and histological characteristics, inasmuch as this procedure is essential to provide a suitable treatment and establish a prognosis.
abstractGer	INTRODUCTION AND OBJECTIVE: The peripheral and central giant cell lesions (PGCL and CGCL) are a group of pathological entities with similar histopathological features and whose origin has not been fully elucidated. The former is reactive and the latter exhibits a non-neoplastic proliferative behavior. This article aims to review the literature on peripheral giant cell lesions (PGCL) and central giant cell lesions (CGCL) by discussing the most important aspects pertaining to each of them. RESULTS: These lesions are found in different locations and show diverse clinical signs despite having the same histopathological features. The treatment consists in the surgical resection by different techniques depending on the type of the lesion and clinical conditions. In the case of CGCL, drug therapy may also be employed. CONCLUSION: Although there is no consensus in the literature, it is essential to know the etiology of these lesions as well as the exact origin of the giant cells. Due to their singular biological behavior, it is of utmost importance to establish a differential diagnosis between the two lesions and other processes that have similar clinical, radiological and histological characteristics, inasmuch as this procedure is essential to provide a suitable treatment and establish a prognosis.
abstract_unstemmed	INTRODUCTION AND OBJECTIVE: The peripheral and central giant cell lesions (PGCL and CGCL) are a group of pathological entities with similar histopathological features and whose origin has not been fully elucidated. The former is reactive and the latter exhibits a non-neoplastic proliferative behavior. This article aims to review the literature on peripheral giant cell lesions (PGCL) and central giant cell lesions (CGCL) by discussing the most important aspects pertaining to each of them. RESULTS: These lesions are found in different locations and show diverse clinical signs despite having the same histopathological features. The treatment consists in the surgical resection by different techniques depending on the type of the lesion and clinical conditions. In the case of CGCL, drug therapy may also be employed. CONCLUSION: Although there is no consensus in the literature, it is essential to know the etiology of these lesions as well as the exact origin of the giant cells. Due to their singular biological behavior, it is of utmost importance to establish a differential diagnosis between the two lesions and other processes that have similar clinical, radiological and histological characteristics, inasmuch as this procedure is essential to provide a suitable treatment and establish a prognosis.
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title_short	Peripheral and central giant cell lesions: etiology, origin of giant cells, diagnosis and treatment
url	https://doi.org/10.1590/S1676-24442013000600011 https://doaj.org/article/4c6fad4ced364675b3714cdbeab4fe36 http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1676-24442013000600011&lng=en&tlng=en https://doaj.org/toc/1678-4774
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Peripheral and central giant cell lesions: etiology, origin of giant cells, diagnosis and treatment

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