Hyperpigmentation as a peculiar presentation of mycosis fungoides

Abstract Hyperpigmented mycosis fungoides is an extremely rare subtype of mycosis fungoides. It presents as multiple pigmented macules and patches without poikilodermatous changes and characterized by a CD8+ phenotype on immunohistochemistry. This report describes a typical case of hyperpigmented my...
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Autor*in:	Ying-Yi Lu [verfasserIn] Chieh-Hsin Wu [verfasserIn] Chun-Ching Lu [verfasserIn] Chien-Hui Hong [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch ; Portugiesisch

Erschienen:	2017

Schlagwörter:	Antigens, CD8 Hyperpigmentation Mycosis fungoides

Übergeordnetes Werk:	In: Anais Brasileiros de Dermatologia - Sociedade Brasileira de Dermatologia, 2004, 92(2017), 5 suppl 1, Seite 92-94
Übergeordnetes Werk:	volume:92 ; year:2017 ; number:5 suppl 1 ; pages:92-94

Links:	Link aufrufen Link aufrufen Link aufrufen Link aufrufen Journal toc

DOI / URN:	10.1590/abd1806-4841.20175544

Katalog-ID:	DOAJ017757010

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allfields	10.1590/abd1806-4841.20175544 doi (DE-627)DOAJ017757010 (DE-599)DOAJ8d52602a21db4c6fab9b64c978ef976a DE-627 ger DE-627 rakwb eng por RL1-803 Ying-Yi Lu verfasserin aut Hyperpigmentation as a peculiar presentation of mycosis fungoides 2017 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract Hyperpigmented mycosis fungoides is an extremely rare subtype of mycosis fungoides. It presents as multiple pigmented macules and patches without poikilodermatous changes and characterized by a CD8+ phenotype on immunohistochemistry. This report describes a typical case of hyperpigmented mycosis fungoides in a 62-year-old woman, who presented with a 7-year history of multiple hyperpigmented macules and patches on the trunk and right leg with progression over this half a year. Histology and immunohistochemical staining of skin samples confirmed the diagnosis of mycosis fungoides. She received psoralen plus ultraviolet A (PUVA) therapy. After an 8-week treatment, the erythematous changes cleared without recurrence during a 6-month follow-up period. An intractable hyperpigmented patch should raise the clinical suspicion of mycosis fungoides with sequential skin biopsy. Antigens, CD8 Hyperpigmentation Mycosis fungoides Dermatology Chieh-Hsin Wu verfasserin aut Chun-Ching Lu verfasserin aut Chien-Hui Hong verfasserin aut In Anais Brasileiros de Dermatologia Sociedade Brasileira de Dermatologia, 2004 92(2017), 5 suppl 1, Seite 92-94 (DE-627)387478906 (DE-600)2145422-X 03650596 nnns volume:92 year:2017 number:5 suppl 1 pages:92-94 https://doi.org/10.1590/abd1806-4841.20175544 kostenfrei https://doaj.org/article/8d52602a21db4c6fab9b64c978ef976a kostenfrei http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962017001100092&tlng=en kostenfrei http://www.scielo.br/pdf/abd/v92n5s1/0365-0596-abd-92-05-s1-0092.pdf kostenfrei https://doaj.org/toc/0365-0596 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 92 2017 5 suppl 1 92-94
spelling	10.1590/abd1806-4841.20175544 doi (DE-627)DOAJ017757010 (DE-599)DOAJ8d52602a21db4c6fab9b64c978ef976a DE-627 ger DE-627 rakwb eng por RL1-803 Ying-Yi Lu verfasserin aut Hyperpigmentation as a peculiar presentation of mycosis fungoides 2017 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract Hyperpigmented mycosis fungoides is an extremely rare subtype of mycosis fungoides. It presents as multiple pigmented macules and patches without poikilodermatous changes and characterized by a CD8+ phenotype on immunohistochemistry. This report describes a typical case of hyperpigmented mycosis fungoides in a 62-year-old woman, who presented with a 7-year history of multiple hyperpigmented macules and patches on the trunk and right leg with progression over this half a year. Histology and immunohistochemical staining of skin samples confirmed the diagnosis of mycosis fungoides. She received psoralen plus ultraviolet A (PUVA) therapy. After an 8-week treatment, the erythematous changes cleared without recurrence during a 6-month follow-up period. An intractable hyperpigmented patch should raise the clinical suspicion of mycosis fungoides with sequential skin biopsy. Antigens, CD8 Hyperpigmentation Mycosis fungoides Dermatology Chieh-Hsin Wu verfasserin aut Chun-Ching Lu verfasserin aut Chien-Hui Hong verfasserin aut In Anais Brasileiros de Dermatologia Sociedade Brasileira de Dermatologia, 2004 92(2017), 5 suppl 1, Seite 92-94 (DE-627)387478906 (DE-600)2145422-X 03650596 nnns volume:92 year:2017 number:5 suppl 1 pages:92-94 https://doi.org/10.1590/abd1806-4841.20175544 kostenfrei https://doaj.org/article/8d52602a21db4c6fab9b64c978ef976a kostenfrei http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962017001100092&tlng=en kostenfrei http://www.scielo.br/pdf/abd/v92n5s1/0365-0596-abd-92-05-s1-0092.pdf kostenfrei https://doaj.org/toc/0365-0596 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 92 2017 5 suppl 1 92-94
allfields_unstemmed	10.1590/abd1806-4841.20175544 doi (DE-627)DOAJ017757010 (DE-599)DOAJ8d52602a21db4c6fab9b64c978ef976a DE-627 ger DE-627 rakwb eng por RL1-803 Ying-Yi Lu verfasserin aut Hyperpigmentation as a peculiar presentation of mycosis fungoides 2017 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract Hyperpigmented mycosis fungoides is an extremely rare subtype of mycosis fungoides. It presents as multiple pigmented macules and patches without poikilodermatous changes and characterized by a CD8+ phenotype on immunohistochemistry. This report describes a typical case of hyperpigmented mycosis fungoides in a 62-year-old woman, who presented with a 7-year history of multiple hyperpigmented macules and patches on the trunk and right leg with progression over this half a year. Histology and immunohistochemical staining of skin samples confirmed the diagnosis of mycosis fungoides. She received psoralen plus ultraviolet A (PUVA) therapy. After an 8-week treatment, the erythematous changes cleared without recurrence during a 6-month follow-up period. An intractable hyperpigmented patch should raise the clinical suspicion of mycosis fungoides with sequential skin biopsy. Antigens, CD8 Hyperpigmentation Mycosis fungoides Dermatology Chieh-Hsin Wu verfasserin aut Chun-Ching Lu verfasserin aut Chien-Hui Hong verfasserin aut In Anais Brasileiros de Dermatologia Sociedade Brasileira de Dermatologia, 2004 92(2017), 5 suppl 1, Seite 92-94 (DE-627)387478906 (DE-600)2145422-X 03650596 nnns volume:92 year:2017 number:5 suppl 1 pages:92-94 https://doi.org/10.1590/abd1806-4841.20175544 kostenfrei https://doaj.org/article/8d52602a21db4c6fab9b64c978ef976a kostenfrei http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962017001100092&tlng=en kostenfrei http://www.scielo.br/pdf/abd/v92n5s1/0365-0596-abd-92-05-s1-0092.pdf kostenfrei https://doaj.org/toc/0365-0596 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 92 2017 5 suppl 1 92-94
allfieldsGer	10.1590/abd1806-4841.20175544 doi (DE-627)DOAJ017757010 (DE-599)DOAJ8d52602a21db4c6fab9b64c978ef976a DE-627 ger DE-627 rakwb eng por RL1-803 Ying-Yi Lu verfasserin aut Hyperpigmentation as a peculiar presentation of mycosis fungoides 2017 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract Hyperpigmented mycosis fungoides is an extremely rare subtype of mycosis fungoides. It presents as multiple pigmented macules and patches without poikilodermatous changes and characterized by a CD8+ phenotype on immunohistochemistry. This report describes a typical case of hyperpigmented mycosis fungoides in a 62-year-old woman, who presented with a 7-year history of multiple hyperpigmented macules and patches on the trunk and right leg with progression over this half a year. Histology and immunohistochemical staining of skin samples confirmed the diagnosis of mycosis fungoides. She received psoralen plus ultraviolet A (PUVA) therapy. After an 8-week treatment, the erythematous changes cleared without recurrence during a 6-month follow-up period. An intractable hyperpigmented patch should raise the clinical suspicion of mycosis fungoides with sequential skin biopsy. Antigens, CD8 Hyperpigmentation Mycosis fungoides Dermatology Chieh-Hsin Wu verfasserin aut Chun-Ching Lu verfasserin aut Chien-Hui Hong verfasserin aut In Anais Brasileiros de Dermatologia Sociedade Brasileira de Dermatologia, 2004 92(2017), 5 suppl 1, Seite 92-94 (DE-627)387478906 (DE-600)2145422-X 03650596 nnns volume:92 year:2017 number:5 suppl 1 pages:92-94 https://doi.org/10.1590/abd1806-4841.20175544 kostenfrei https://doaj.org/article/8d52602a21db4c6fab9b64c978ef976a kostenfrei http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962017001100092&tlng=en kostenfrei http://www.scielo.br/pdf/abd/v92n5s1/0365-0596-abd-92-05-s1-0092.pdf kostenfrei https://doaj.org/toc/0365-0596 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 92 2017 5 suppl 1 92-94
allfieldsSound	10.1590/abd1806-4841.20175544 doi (DE-627)DOAJ017757010 (DE-599)DOAJ8d52602a21db4c6fab9b64c978ef976a DE-627 ger DE-627 rakwb eng por RL1-803 Ying-Yi Lu verfasserin aut Hyperpigmentation as a peculiar presentation of mycosis fungoides 2017 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract Hyperpigmented mycosis fungoides is an extremely rare subtype of mycosis fungoides. It presents as multiple pigmented macules and patches without poikilodermatous changes and characterized by a CD8+ phenotype on immunohistochemistry. This report describes a typical case of hyperpigmented mycosis fungoides in a 62-year-old woman, who presented with a 7-year history of multiple hyperpigmented macules and patches on the trunk and right leg with progression over this half a year. Histology and immunohistochemical staining of skin samples confirmed the diagnosis of mycosis fungoides. She received psoralen plus ultraviolet A (PUVA) therapy. After an 8-week treatment, the erythematous changes cleared without recurrence during a 6-month follow-up period. An intractable hyperpigmented patch should raise the clinical suspicion of mycosis fungoides with sequential skin biopsy. Antigens, CD8 Hyperpigmentation Mycosis fungoides Dermatology Chieh-Hsin Wu verfasserin aut Chun-Ching Lu verfasserin aut Chien-Hui Hong verfasserin aut In Anais Brasileiros de Dermatologia Sociedade Brasileira de Dermatologia, 2004 92(2017), 5 suppl 1, Seite 92-94 (DE-627)387478906 (DE-600)2145422-X 03650596 nnns volume:92 year:2017 number:5 suppl 1 pages:92-94 https://doi.org/10.1590/abd1806-4841.20175544 kostenfrei https://doaj.org/article/8d52602a21db4c6fab9b64c978ef976a kostenfrei http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962017001100092&tlng=en kostenfrei http://www.scielo.br/pdf/abd/v92n5s1/0365-0596-abd-92-05-s1-0092.pdf kostenfrei https://doaj.org/toc/0365-0596 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 92 2017 5 suppl 1 92-94
language	English Portuguese
source	In Anais Brasileiros de Dermatologia 92(2017), 5 suppl 1, Seite 92-94 volume:92 year:2017 number:5 suppl 1 pages:92-94
sourceStr	In Anais Brasileiros de Dermatologia 92(2017), 5 suppl 1, Seite 92-94 volume:92 year:2017 number:5 suppl 1 pages:92-94
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topic_facet	Antigens, CD8 Hyperpigmentation Mycosis fungoides Dermatology
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container_title	Anais Brasileiros de Dermatologia
authorswithroles_txt_mv	Ying-Yi Lu @@aut@@ Chieh-Hsin Wu @@aut@@ Chun-Ching Lu @@aut@@ Chien-Hui Hong @@aut@@
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callnumber-first	R - Medicine
author	Ying-Yi Lu
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topic_title	RL1-803 Hyperpigmentation as a peculiar presentation of mycosis fungoides Antigens, CD8 Hyperpigmentation Mycosis fungoides
topic	misc RL1-803 misc Antigens, CD8 misc Hyperpigmentation misc Mycosis fungoides misc Dermatology
topic_unstemmed	misc RL1-803 misc Antigens, CD8 misc Hyperpigmentation misc Mycosis fungoides misc Dermatology
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title	Hyperpigmentation as a peculiar presentation of mycosis fungoides
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title_full	Hyperpigmentation as a peculiar presentation of mycosis fungoides
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title_sort	hyperpigmentation as a peculiar presentation of mycosis fungoides
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title_auth	Hyperpigmentation as a peculiar presentation of mycosis fungoides
abstract	Abstract Hyperpigmented mycosis fungoides is an extremely rare subtype of mycosis fungoides. It presents as multiple pigmented macules and patches without poikilodermatous changes and characterized by a CD8+ phenotype on immunohistochemistry. This report describes a typical case of hyperpigmented mycosis fungoides in a 62-year-old woman, who presented with a 7-year history of multiple hyperpigmented macules and patches on the trunk and right leg with progression over this half a year. Histology and immunohistochemical staining of skin samples confirmed the diagnosis of mycosis fungoides. She received psoralen plus ultraviolet A (PUVA) therapy. After an 8-week treatment, the erythematous changes cleared without recurrence during a 6-month follow-up period. An intractable hyperpigmented patch should raise the clinical suspicion of mycosis fungoides with sequential skin biopsy.
abstractGer	Abstract Hyperpigmented mycosis fungoides is an extremely rare subtype of mycosis fungoides. It presents as multiple pigmented macules and patches without poikilodermatous changes and characterized by a CD8+ phenotype on immunohistochemistry. This report describes a typical case of hyperpigmented mycosis fungoides in a 62-year-old woman, who presented with a 7-year history of multiple hyperpigmented macules and patches on the trunk and right leg with progression over this half a year. Histology and immunohistochemical staining of skin samples confirmed the diagnosis of mycosis fungoides. She received psoralen plus ultraviolet A (PUVA) therapy. After an 8-week treatment, the erythematous changes cleared without recurrence during a 6-month follow-up period. An intractable hyperpigmented patch should raise the clinical suspicion of mycosis fungoides with sequential skin biopsy.
abstract_unstemmed	Abstract Hyperpigmented mycosis fungoides is an extremely rare subtype of mycosis fungoides. It presents as multiple pigmented macules and patches without poikilodermatous changes and characterized by a CD8+ phenotype on immunohistochemistry. This report describes a typical case of hyperpigmented mycosis fungoides in a 62-year-old woman, who presented with a 7-year history of multiple hyperpigmented macules and patches on the trunk and right leg with progression over this half a year. Histology and immunohistochemical staining of skin samples confirmed the diagnosis of mycosis fungoides. She received psoralen plus ultraviolet A (PUVA) therapy. After an 8-week treatment, the erythematous changes cleared without recurrence during a 6-month follow-up period. An intractable hyperpigmented patch should raise the clinical suspicion of mycosis fungoides with sequential skin biopsy.
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title_short	Hyperpigmentation as a peculiar presentation of mycosis fungoides
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Hyperpigmentation as a peculiar presentation of mycosis fungoides

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