Risk factors and features of recurrent bacterial complications of upper respiratory tract viral infections in children.
. The aim of the study was to determine risk factors for recurrent bacterial complications of the upper respiratory tract viral infection (URTI) in children, as well as the clinical and immunological features of the course of such complications. We enrolled 214 children aged 3-18 years with URTIs co...
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| Autor*in: |
A. V. Karpenko [verfasserIn] |
|---|
| Format: |
E-Artikel |
|---|---|
| Sprache: |
Englisch ; Ukrainisch |
| Erschienen: |
2017 |
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| Schlagwörter: |
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| Übergeordnetes Werk: |
In: Medičnì Perspektivi - Dnipro State Medical University, 2019, 22(2017), 3, Seite 88-93 |
|---|---|
| Übergeordnetes Werk: |
volume:22 ; year:2017 ; number:3 ; pages:88-93 |
| Links: |
|---|
| DOI / URN: |
10.26641/2307-0404.2017.3.111931 |
|---|
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DOAJ018142575 |
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| 520 | |a . The aim of the study was to determine risk factors for recurrent bacterial complications of the upper respiratory tract viral infection (URTI) in children, as well as the clinical and immunological features of the course of such complications. We enrolled 214 children aged 3-18 years with URTIs complicated with acute otitis media or acute bacterial rhinosinusitis. Frequency of bacterial complications of URI in 128 children was low (group I) and in 86 children it met the criteria of recurrent course (group II). In addition to the standard examination, lysozyme levels in the oropharyngeal secretion were determined three times during the disease. It was found that children of group II were characterized by an early debut of respiratory morbidity (at the age of 6.00 (4.00, 12.00) months against 13.00 (4.50, 16.00) months in children of group I (p<0,0001), as well as a longer duration of catarrhal and intoxication syndromes in similar forms of the disease. The most significant risk factors for the formation of the recurring complication pattern were maternal smoking (OR=2.73, 95% CI [1.34, 5.48]), along with gastroenterological pathology and frequent URTI in the mother and a shortened period of breastfeeding. In children with recurrent bacterial complications of URTI, there was an impaired local resistance of the upper respiratory tract mucous membranes (as a decrease in the concentrations of lysozyme) in all periods of the disease, which persisted after recovery. | ||
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10.26641/2307-0404.2017.3.111931 doi (DE-627)DOAJ018142575 (DE-599)DOAJ1930d5295ac346ebbd629b6b9f2ae3d7 DE-627 ger DE-627 rakwb eng ukr A. V. Karpenko verfasserin aut Risk factors and features of recurrent bacterial complications of upper respiratory tract viral infections in children. 2017 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier . The aim of the study was to determine risk factors for recurrent bacterial complications of the upper respiratory tract viral infection (URTI) in children, as well as the clinical and immunological features of the course of such complications. We enrolled 214 children aged 3-18 years with URTIs complicated with acute otitis media or acute bacterial rhinosinusitis. Frequency of bacterial complications of URI in 128 children was low (group I) and in 86 children it met the criteria of recurrent course (group II). In addition to the standard examination, lysozyme levels in the oropharyngeal secretion were determined three times during the disease. It was found that children of group II were characterized by an early debut of respiratory morbidity (at the age of 6.00 (4.00, 12.00) months against 13.00 (4.50, 16.00) months in children of group I (p<0,0001), as well as a longer duration of catarrhal and intoxication syndromes in similar forms of the disease. The most significant risk factors for the formation of the recurring complication pattern were maternal smoking (OR=2.73, 95% CI [1.34, 5.48]), along with gastroenterological pathology and frequent URTI in the mother and a shortened period of breastfeeding. In children with recurrent bacterial complications of URTI, there was an impaired local resistance of the upper respiratory tract mucous membranes (as a decrease in the concentrations of lysozyme) in all periods of the disease, which persisted after recovery. acute otitis media acute rhinosinusitis URTI lysozyme children Medicine R In Medičnì Perspektivi Dnipro State Medical University, 2019 22(2017), 3, Seite 88-93 (DE-627)1760592307 23070404 nnns volume:22 year:2017 number:3 pages:88-93 https://doi.org/10.26641/2307-0404.2017.3.111931 kostenfrei https://doaj.org/article/1930d5295ac346ebbd629b6b9f2ae3d7 kostenfrei http://journals.uran.ua/index.php/2307-0404/article/view/111931 kostenfrei https://doaj.org/toc/2307-0404 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ AR 22 2017 3 88-93 |
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Risk factors and features of recurrent bacterial complications of upper respiratory tract viral infections in children. |
| abstract |
. The aim of the study was to determine risk factors for recurrent bacterial complications of the upper respiratory tract viral infection (URTI) in children, as well as the clinical and immunological features of the course of such complications. We enrolled 214 children aged 3-18 years with URTIs complicated with acute otitis media or acute bacterial rhinosinusitis. Frequency of bacterial complications of URI in 128 children was low (group I) and in 86 children it met the criteria of recurrent course (group II). In addition to the standard examination, lysozyme levels in the oropharyngeal secretion were determined three times during the disease. It was found that children of group II were characterized by an early debut of respiratory morbidity (at the age of 6.00 (4.00, 12.00) months against 13.00 (4.50, 16.00) months in children of group I (p<0,0001), as well as a longer duration of catarrhal and intoxication syndromes in similar forms of the disease. The most significant risk factors for the formation of the recurring complication pattern were maternal smoking (OR=2.73, 95% CI [1.34, 5.48]), along with gastroenterological pathology and frequent URTI in the mother and a shortened period of breastfeeding. In children with recurrent bacterial complications of URTI, there was an impaired local resistance of the upper respiratory tract mucous membranes (as a decrease in the concentrations of lysozyme) in all periods of the disease, which persisted after recovery. |
| abstractGer |
. The aim of the study was to determine risk factors for recurrent bacterial complications of the upper respiratory tract viral infection (URTI) in children, as well as the clinical and immunological features of the course of such complications. We enrolled 214 children aged 3-18 years with URTIs complicated with acute otitis media or acute bacterial rhinosinusitis. Frequency of bacterial complications of URI in 128 children was low (group I) and in 86 children it met the criteria of recurrent course (group II). In addition to the standard examination, lysozyme levels in the oropharyngeal secretion were determined three times during the disease. It was found that children of group II were characterized by an early debut of respiratory morbidity (at the age of 6.00 (4.00, 12.00) months against 13.00 (4.50, 16.00) months in children of group I (p<0,0001), as well as a longer duration of catarrhal and intoxication syndromes in similar forms of the disease. The most significant risk factors for the formation of the recurring complication pattern were maternal smoking (OR=2.73, 95% CI [1.34, 5.48]), along with gastroenterological pathology and frequent URTI in the mother and a shortened period of breastfeeding. In children with recurrent bacterial complications of URTI, there was an impaired local resistance of the upper respiratory tract mucous membranes (as a decrease in the concentrations of lysozyme) in all periods of the disease, which persisted after recovery. |
| abstract_unstemmed |
. The aim of the study was to determine risk factors for recurrent bacterial complications of the upper respiratory tract viral infection (URTI) in children, as well as the clinical and immunological features of the course of such complications. We enrolled 214 children aged 3-18 years with URTIs complicated with acute otitis media or acute bacterial rhinosinusitis. Frequency of bacterial complications of URI in 128 children was low (group I) and in 86 children it met the criteria of recurrent course (group II). In addition to the standard examination, lysozyme levels in the oropharyngeal secretion were determined three times during the disease. It was found that children of group II were characterized by an early debut of respiratory morbidity (at the age of 6.00 (4.00, 12.00) months against 13.00 (4.50, 16.00) months in children of group I (p<0,0001), as well as a longer duration of catarrhal and intoxication syndromes in similar forms of the disease. The most significant risk factors for the formation of the recurring complication pattern were maternal smoking (OR=2.73, 95% CI [1.34, 5.48]), along with gastroenterological pathology and frequent URTI in the mother and a shortened period of breastfeeding. In children with recurrent bacterial complications of URTI, there was an impaired local resistance of the upper respiratory tract mucous membranes (as a decrease in the concentrations of lysozyme) in all periods of the disease, which persisted after recovery. |
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Risk factors and features of recurrent bacterial complications of upper respiratory tract viral infections in children. |
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https://doi.org/10.26641/2307-0404.2017.3.111931 https://doaj.org/article/1930d5295ac346ebbd629b6b9f2ae3d7 http://journals.uran.ua/index.php/2307-0404/article/view/111931 https://doaj.org/toc/2307-0404 |
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10.26641/2307-0404.2017.3.111931 |
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2024-07-03T16:11:22.863Z |
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