Three Novel Biphenanthrene Derivatives and a New Phenylpropanoid Ester from <i<Aerides multiflora</i< and Their <i<α</i<-Glucosidase Inhibitory Activity
A phytochemical investigation on the whole plants of <i<Aerides multiflora</i< revealed the presence of three new biphenanthrene derivatives named aerimultins A–C (<b<1</b<–<b<3</b<) and a new natural phenylpropanoid ester dihydrosinapyl dihydroferulate (<b<...
Ausführliche Beschreibung
Autor*in: |
May Thazin Thant [verfasserIn] Boonchoo Sritularak [verfasserIn] Nutputsorn Chatsumpun [verfasserIn] Wanwimon Mekboonsonglarp [verfasserIn] Yanyong Punpreuk [verfasserIn] Kittisak Likhitwitayawuid [verfasserIn] |
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E-Artikel |
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Sprache: |
Englisch |
Erschienen: |
2021 |
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Übergeordnetes Werk: |
In: Plants - MDPI AG, 2013, 10(2021), 2, p 385 |
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Übergeordnetes Werk: |
volume:10 ; year:2021 ; number:2, p 385 |
Links: |
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DOI / URN: |
10.3390/plants10020385 |
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Katalog-ID: |
DOAJ019433123 |
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10.3390/plants10020385 doi (DE-627)DOAJ019433123 (DE-599)DOAJ4e92dc965f374d02b6a10e0beac8d58c DE-627 ger DE-627 rakwb eng QK1-989 May Thazin Thant verfasserin aut Three Novel Biphenanthrene Derivatives and a New Phenylpropanoid Ester from <i<Aerides multiflora</i< and Their <i<α</i<-Glucosidase Inhibitory Activity 2021 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier A phytochemical investigation on the whole plants of <i<Aerides multiflora</i< revealed the presence of three new biphenanthrene derivatives named aerimultins A–C (<b<1</b<–<b<3</b<) and a new natural phenylpropanoid ester dihydrosinapyl dihydroferulate (<b<4</b<), together with six known compounds (<b<5</b<–<b<10</b<). The structures of the new compounds were elucidated by analysis of their spectroscopic data. All of the isolates were evaluated for their <i<α</i<-glucosidase inhibitory activity. Aerimultin C (<b<3</b<) showed the most potent activity. The other compounds, except for compound <b<4</b<, also exhibited stronger activity than the positive control acarbose. Compound <b<3</b< showed non-competitive inhibition of the enzyme as determined from a Lineweaver–Burk plot. This study is the first phytochemical and biological investigation of <i<A. multiflora</i<. <i<Aerides multiflora</i< Orchidaceae <i<α</i<-glucosidase inhibition biphenanthrene derivatives phenylpropanoid ester Botany Boonchoo Sritularak verfasserin aut Nutputsorn Chatsumpun verfasserin aut Wanwimon Mekboonsonglarp verfasserin aut Yanyong Punpreuk verfasserin aut Kittisak Likhitwitayawuid verfasserin aut In Plants MDPI AG, 2013 10(2021), 2, p 385 (DE-627)737288345 (DE-600)2704341-1 22237747 nnns volume:10 year:2021 number:2, p 385 https://doi.org/10.3390/plants10020385 kostenfrei https://doaj.org/article/4e92dc965f374d02b6a10e0beac8d58c kostenfrei https://www.mdpi.com/2223-7747/10/2/385 kostenfrei https://doaj.org/toc/2223-7747 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 10 2021 2, p 385 |
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Three Novel Biphenanthrene Derivatives and a New Phenylpropanoid Ester from <i<Aerides multiflora</i< and Their <i<α</i<-Glucosidase Inhibitory Activity |
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A phytochemical investigation on the whole plants of <i<Aerides multiflora</i< revealed the presence of three new biphenanthrene derivatives named aerimultins A–C (<b<1</b<–<b<3</b<) and a new natural phenylpropanoid ester dihydrosinapyl dihydroferulate (<b<4</b<), together with six known compounds (<b<5</b<–<b<10</b<). The structures of the new compounds were elucidated by analysis of their spectroscopic data. All of the isolates were evaluated for their <i<α</i<-glucosidase inhibitory activity. Aerimultin C (<b<3</b<) showed the most potent activity. The other compounds, except for compound <b<4</b<, also exhibited stronger activity than the positive control acarbose. Compound <b<3</b< showed non-competitive inhibition of the enzyme as determined from a Lineweaver–Burk plot. This study is the first phytochemical and biological investigation of <i<A. multiflora</i<. |
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A phytochemical investigation on the whole plants of <i<Aerides multiflora</i< revealed the presence of three new biphenanthrene derivatives named aerimultins A–C (<b<1</b<–<b<3</b<) and a new natural phenylpropanoid ester dihydrosinapyl dihydroferulate (<b<4</b<), together with six known compounds (<b<5</b<–<b<10</b<). The structures of the new compounds were elucidated by analysis of their spectroscopic data. All of the isolates were evaluated for their <i<α</i<-glucosidase inhibitory activity. Aerimultin C (<b<3</b<) showed the most potent activity. The other compounds, except for compound <b<4</b<, also exhibited stronger activity than the positive control acarbose. Compound <b<3</b< showed non-competitive inhibition of the enzyme as determined from a Lineweaver–Burk plot. This study is the first phytochemical and biological investigation of <i<A. multiflora</i<. |
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A phytochemical investigation on the whole plants of <i<Aerides multiflora</i< revealed the presence of three new biphenanthrene derivatives named aerimultins A–C (<b<1</b<–<b<3</b<) and a new natural phenylpropanoid ester dihydrosinapyl dihydroferulate (<b<4</b<), together with six known compounds (<b<5</b<–<b<10</b<). The structures of the new compounds were elucidated by analysis of their spectroscopic data. All of the isolates were evaluated for their <i<α</i<-glucosidase inhibitory activity. Aerimultin C (<b<3</b<) showed the most potent activity. The other compounds, except for compound <b<4</b<, also exhibited stronger activity than the positive control acarbose. Compound <b<3</b< showed non-competitive inhibition of the enzyme as determined from a Lineweaver–Burk plot. This study is the first phytochemical and biological investigation of <i<A. multiflora</i<. |
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Three Novel Biphenanthrene Derivatives and a New Phenylpropanoid Ester from <i<Aerides multiflora</i< and Their <i<α</i<-Glucosidase Inhibitory Activity |
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