Agitation in Dementia: Relation to Core Cerebrospinal Fluid Biomarker Levels

Background: The objective of this study was to examine the associations of agitation with the cerebrospinal fluid dementia biomarkers total-tau (T-tau), phosphorylated-tau (P-tau) and Aβ1-42. Methods: One hundred patients (mean age ± SD, 78.6 ± 7.5 years) with dementia and neuropsychiatric symptoms,...
Ausführliche Beschreibung

Gespeichert in:

Autor*in:	Victor Bloniecki [verfasserIn] Dag Aarsland [verfasserIn] Jeffrey Cummings [verfasserIn] Kaj Blennow [verfasserIn] Yvonne Freund-Levi [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2014

Schlagwörter:	Dementia Agitation CMAI Cerebrospinal fluid (CSF) Dementia biomarkers Neurofibrillary tangles Behavioral and psychological symptoms in dementia (BPSD)

Übergeordnetes Werk:	In: Dementia and Geriatric Cognitive Disorders Extra - Karger Publishers, 2013, 4(2014), 2, Seite 335-343
Übergeordnetes Werk:	volume:4 ; year:2014 ; number:2 ; pages:335-343

Links:	Link aufrufen Link aufrufen Link aufrufen Journal toc

DOI / URN:	10.1159/000363500

Katalog-ID:	DOAJ019644310

Internformat


LEADER	01000caa a22002652 4500
001	DOAJ019644310
003	DE-627
005	20230310111905.0
007	cr uuu---uuuuu
008	230226s2014 xx \|\|\|\|\|o 00\| \|\|eng c
024	7		\|a 10.1159/000363500 \|2 doi
035			\|a (DE-627)DOAJ019644310
035			\|a (DE-599)DOAJ74df7ac1284b44a4a0a269f7a96aa969
040			\|a DE-627 \|b ger \|c DE-627 \|e rakwb
041			\|a eng
050		0	\|a RC346-429
050		0	\|a RC952-954.6
100	0		\|a Victor Bloniecki \|e verfasserin \|4 aut
245	1	0	\|a Agitation in Dementia: Relation to Core Cerebrospinal Fluid Biomarker Levels
264		1	\|c 2014
336			\|a Text \|b txt \|2 rdacontent
337			\|a Computermedien \|b c \|2 rdamedia
338			\|a Online-Ressource \|b cr \|2 rdacarrier
520			\|a Background: The objective of this study was to examine the associations of agitation with the cerebrospinal fluid dementia biomarkers total-tau (T-tau), phosphorylated-tau (P-tau) and Aβ1-42. Methods: One hundred patients (mean age ± SD, 78.6 ± 7.5 years) with dementia and neuropsychiatric symptoms, of whom 67% were female, were included. Agitation was measured using the Cohen-Mansfield Agitation Inventory (CMAI; 46.5 ± 11.8 points). Results: Total CMAI correlated with T-tau [rs (31) = 0.36, p = 0.04] and P-tau [rs (31) = 0.35, p = 0.05] in patients with Alzheimer's disease (AD; n = 33) but not in the total dementia population (n = 95). Conclusions: Our results suggest that tau-mediated pathology including neurofibrillary tangles and the intensity of the disease process might be associated with agitation in AD.
650		4	\|a Dementia
650		4	\|a Agitation
650		4	\|a CMAI
650		4	\|a Cerebrospinal fluid (CSF)
650		4	\|a Dementia biomarkers
650		4	\|a Neurofibrillary tangles
650		4	\|a Behavioral and psychological symptoms in dementia (BPSD)
653		0	\|a Neurology. Diseases of the nervous system
653		0	\|a Geriatrics
700	0		\|a Dag Aarsland \|e verfasserin \|4 aut
700	0		\|a Jeffrey Cummings \|e verfasserin \|4 aut
700	0		\|a Kaj Blennow \|e verfasserin \|4 aut
700	0		\|a Yvonne Freund-Levi \|e verfasserin \|4 aut
773	0	8	\|i In \|t Dementia and Geriatric Cognitive Disorders Extra \|d Karger Publishers, 2013 \|g 4(2014), 2, Seite 335-343 \|w (DE-627)665673434 \|w (DE-600)2621464-7 \|x 16645464 \|7 nnns
773	1	8	\|g volume:4 \|g year:2014 \|g number:2 \|g pages:335-343
856	4	0	\|u https://doi.org/10.1159/000363500 \|z kostenfrei
856	4	0	\|u https://doaj.org/article/74df7ac1284b44a4a0a269f7a96aa969 \|z kostenfrei
856	4	0	\|u http://www.karger.com/Article/FullText/363500 \|z kostenfrei
856	4	2	\|u https://doaj.org/toc/1664-5464 \|y Journal toc \|z kostenfrei
912			\|a GBV_USEFLAG_A
912			\|a SYSFLAG_A
912			\|a GBV_DOAJ
912			\|a GBV_ILN_20
912			\|a GBV_ILN_22
912			\|a GBV_ILN_23
912			\|a GBV_ILN_24
912			\|a GBV_ILN_31
912			\|a GBV_ILN_39
912			\|a GBV_ILN_40
912			\|a GBV_ILN_60
912			\|a GBV_ILN_62
912			\|a GBV_ILN_63
912			\|a GBV_ILN_65
912			\|a GBV_ILN_69
912			\|a GBV_ILN_73
912			\|a GBV_ILN_74
912			\|a GBV_ILN_95
912			\|a GBV_ILN_105
912			\|a GBV_ILN_110
912			\|a GBV_ILN_151
912			\|a GBV_ILN_161
912			\|a GBV_ILN_170
912			\|a GBV_ILN_206
912			\|a GBV_ILN_213
912			\|a GBV_ILN_230
912			\|a GBV_ILN_285
912			\|a GBV_ILN_293
912			\|a GBV_ILN_602
912			\|a GBV_ILN_2014
912			\|a GBV_ILN_2018
912			\|a GBV_ILN_4012
912			\|a GBV_ILN_4037
912			\|a GBV_ILN_4112
912			\|a GBV_ILN_4125
912			\|a GBV_ILN_4126
912			\|a GBV_ILN_4249
912			\|a GBV_ILN_4305
912			\|a GBV_ILN_4306
912			\|a GBV_ILN_4307
912			\|a GBV_ILN_4313
912			\|a GBV_ILN_4322
912			\|a GBV_ILN_4323
912			\|a GBV_ILN_4324
912			\|a GBV_ILN_4325
912			\|a GBV_ILN_4338
912			\|a GBV_ILN_4367
912			\|a GBV_ILN_4700
951			\|a AR
952			\|d 4 \|j 2014 \|e 2 \|h 335-343

Indexfelder

author_variant	v b vb d a da j c jc k b kb y f l yfl
matchkey_str	article:16645464:2014----::gttoidmnirltotcrcrbopnll
hierarchy_sort_str	2014
callnumber-subject-code	RC
publishDate	2014
allfields	10.1159/000363500 doi (DE-627)DOAJ019644310 (DE-599)DOAJ74df7ac1284b44a4a0a269f7a96aa969 DE-627 ger DE-627 rakwb eng RC346-429 RC952-954.6 Victor Bloniecki verfasserin aut Agitation in Dementia: Relation to Core Cerebrospinal Fluid Biomarker Levels 2014 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background: The objective of this study was to examine the associations of agitation with the cerebrospinal fluid dementia biomarkers total-tau (T-tau), phosphorylated-tau (P-tau) and Aβ1-42. Methods: One hundred patients (mean age ± SD, 78.6 ± 7.5 years) with dementia and neuropsychiatric symptoms, of whom 67% were female, were included. Agitation was measured using the Cohen-Mansfield Agitation Inventory (CMAI; 46.5 ± 11.8 points). Results: Total CMAI correlated with T-tau [rs (31) = 0.36, p = 0.04] and P-tau [rs (31) = 0.35, p = 0.05] in patients with Alzheimer's disease (AD; n = 33) but not in the total dementia population (n = 95). Conclusions: Our results suggest that tau-mediated pathology including neurofibrillary tangles and the intensity of the disease process might be associated with agitation in AD. Dementia Agitation CMAI Cerebrospinal fluid (CSF) Dementia biomarkers Neurofibrillary tangles Behavioral and psychological symptoms in dementia (BPSD) Neurology. Diseases of the nervous system Geriatrics Dag Aarsland verfasserin aut Jeffrey Cummings verfasserin aut Kaj Blennow verfasserin aut Yvonne Freund-Levi verfasserin aut In Dementia and Geriatric Cognitive Disorders Extra Karger Publishers, 2013 4(2014), 2, Seite 335-343 (DE-627)665673434 (DE-600)2621464-7 16645464 nnns volume:4 year:2014 number:2 pages:335-343 https://doi.org/10.1159/000363500 kostenfrei https://doaj.org/article/74df7ac1284b44a4a0a269f7a96aa969 kostenfrei http://www.karger.com/Article/FullText/363500 kostenfrei https://doaj.org/toc/1664-5464 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_2018 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 4 2014 2 335-343
spelling	10.1159/000363500 doi (DE-627)DOAJ019644310 (DE-599)DOAJ74df7ac1284b44a4a0a269f7a96aa969 DE-627 ger DE-627 rakwb eng RC346-429 RC952-954.6 Victor Bloniecki verfasserin aut Agitation in Dementia: Relation to Core Cerebrospinal Fluid Biomarker Levels 2014 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background: The objective of this study was to examine the associations of agitation with the cerebrospinal fluid dementia biomarkers total-tau (T-tau), phosphorylated-tau (P-tau) and Aβ1-42. Methods: One hundred patients (mean age ± SD, 78.6 ± 7.5 years) with dementia and neuropsychiatric symptoms, of whom 67% were female, were included. Agitation was measured using the Cohen-Mansfield Agitation Inventory (CMAI; 46.5 ± 11.8 points). Results: Total CMAI correlated with T-tau [rs (31) = 0.36, p = 0.04] and P-tau [rs (31) = 0.35, p = 0.05] in patients with Alzheimer's disease (AD; n = 33) but not in the total dementia population (n = 95). Conclusions: Our results suggest that tau-mediated pathology including neurofibrillary tangles and the intensity of the disease process might be associated with agitation in AD. Dementia Agitation CMAI Cerebrospinal fluid (CSF) Dementia biomarkers Neurofibrillary tangles Behavioral and psychological symptoms in dementia (BPSD) Neurology. Diseases of the nervous system Geriatrics Dag Aarsland verfasserin aut Jeffrey Cummings verfasserin aut Kaj Blennow verfasserin aut Yvonne Freund-Levi verfasserin aut In Dementia and Geriatric Cognitive Disorders Extra Karger Publishers, 2013 4(2014), 2, Seite 335-343 (DE-627)665673434 (DE-600)2621464-7 16645464 nnns volume:4 year:2014 number:2 pages:335-343 https://doi.org/10.1159/000363500 kostenfrei https://doaj.org/article/74df7ac1284b44a4a0a269f7a96aa969 kostenfrei http://www.karger.com/Article/FullText/363500 kostenfrei https://doaj.org/toc/1664-5464 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_2018 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 4 2014 2 335-343
allfields_unstemmed	10.1159/000363500 doi (DE-627)DOAJ019644310 (DE-599)DOAJ74df7ac1284b44a4a0a269f7a96aa969 DE-627 ger DE-627 rakwb eng RC346-429 RC952-954.6 Victor Bloniecki verfasserin aut Agitation in Dementia: Relation to Core Cerebrospinal Fluid Biomarker Levels 2014 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background: The objective of this study was to examine the associations of agitation with the cerebrospinal fluid dementia biomarkers total-tau (T-tau), phosphorylated-tau (P-tau) and Aβ1-42. Methods: One hundred patients (mean age ± SD, 78.6 ± 7.5 years) with dementia and neuropsychiatric symptoms, of whom 67% were female, were included. Agitation was measured using the Cohen-Mansfield Agitation Inventory (CMAI; 46.5 ± 11.8 points). Results: Total CMAI correlated with T-tau [rs (31) = 0.36, p = 0.04] and P-tau [rs (31) = 0.35, p = 0.05] in patients with Alzheimer's disease (AD; n = 33) but not in the total dementia population (n = 95). Conclusions: Our results suggest that tau-mediated pathology including neurofibrillary tangles and the intensity of the disease process might be associated with agitation in AD. Dementia Agitation CMAI Cerebrospinal fluid (CSF) Dementia biomarkers Neurofibrillary tangles Behavioral and psychological symptoms in dementia (BPSD) Neurology. Diseases of the nervous system Geriatrics Dag Aarsland verfasserin aut Jeffrey Cummings verfasserin aut Kaj Blennow verfasserin aut Yvonne Freund-Levi verfasserin aut In Dementia and Geriatric Cognitive Disorders Extra Karger Publishers, 2013 4(2014), 2, Seite 335-343 (DE-627)665673434 (DE-600)2621464-7 16645464 nnns volume:4 year:2014 number:2 pages:335-343 https://doi.org/10.1159/000363500 kostenfrei https://doaj.org/article/74df7ac1284b44a4a0a269f7a96aa969 kostenfrei http://www.karger.com/Article/FullText/363500 kostenfrei https://doaj.org/toc/1664-5464 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_2018 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 4 2014 2 335-343
allfieldsGer	10.1159/000363500 doi (DE-627)DOAJ019644310 (DE-599)DOAJ74df7ac1284b44a4a0a269f7a96aa969 DE-627 ger DE-627 rakwb eng RC346-429 RC952-954.6 Victor Bloniecki verfasserin aut Agitation in Dementia: Relation to Core Cerebrospinal Fluid Biomarker Levels 2014 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background: The objective of this study was to examine the associations of agitation with the cerebrospinal fluid dementia biomarkers total-tau (T-tau), phosphorylated-tau (P-tau) and Aβ1-42. Methods: One hundred patients (mean age ± SD, 78.6 ± 7.5 years) with dementia and neuropsychiatric symptoms, of whom 67% were female, were included. Agitation was measured using the Cohen-Mansfield Agitation Inventory (CMAI; 46.5 ± 11.8 points). Results: Total CMAI correlated with T-tau [rs (31) = 0.36, p = 0.04] and P-tau [rs (31) = 0.35, p = 0.05] in patients with Alzheimer's disease (AD; n = 33) but not in the total dementia population (n = 95). Conclusions: Our results suggest that tau-mediated pathology including neurofibrillary tangles and the intensity of the disease process might be associated with agitation in AD. Dementia Agitation CMAI Cerebrospinal fluid (CSF) Dementia biomarkers Neurofibrillary tangles Behavioral and psychological symptoms in dementia (BPSD) Neurology. Diseases of the nervous system Geriatrics Dag Aarsland verfasserin aut Jeffrey Cummings verfasserin aut Kaj Blennow verfasserin aut Yvonne Freund-Levi verfasserin aut In Dementia and Geriatric Cognitive Disorders Extra Karger Publishers, 2013 4(2014), 2, Seite 335-343 (DE-627)665673434 (DE-600)2621464-7 16645464 nnns volume:4 year:2014 number:2 pages:335-343 https://doi.org/10.1159/000363500 kostenfrei https://doaj.org/article/74df7ac1284b44a4a0a269f7a96aa969 kostenfrei http://www.karger.com/Article/FullText/363500 kostenfrei https://doaj.org/toc/1664-5464 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_2018 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 4 2014 2 335-343
allfieldsSound	10.1159/000363500 doi (DE-627)DOAJ019644310 (DE-599)DOAJ74df7ac1284b44a4a0a269f7a96aa969 DE-627 ger DE-627 rakwb eng RC346-429 RC952-954.6 Victor Bloniecki verfasserin aut Agitation in Dementia: Relation to Core Cerebrospinal Fluid Biomarker Levels 2014 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background: The objective of this study was to examine the associations of agitation with the cerebrospinal fluid dementia biomarkers total-tau (T-tau), phosphorylated-tau (P-tau) and Aβ1-42. Methods: One hundred patients (mean age ± SD, 78.6 ± 7.5 years) with dementia and neuropsychiatric symptoms, of whom 67% were female, were included. Agitation was measured using the Cohen-Mansfield Agitation Inventory (CMAI; 46.5 ± 11.8 points). Results: Total CMAI correlated with T-tau [rs (31) = 0.36, p = 0.04] and P-tau [rs (31) = 0.35, p = 0.05] in patients with Alzheimer's disease (AD; n = 33) but not in the total dementia population (n = 95). Conclusions: Our results suggest that tau-mediated pathology including neurofibrillary tangles and the intensity of the disease process might be associated with agitation in AD. Dementia Agitation CMAI Cerebrospinal fluid (CSF) Dementia biomarkers Neurofibrillary tangles Behavioral and psychological symptoms in dementia (BPSD) Neurology. Diseases of the nervous system Geriatrics Dag Aarsland verfasserin aut Jeffrey Cummings verfasserin aut Kaj Blennow verfasserin aut Yvonne Freund-Levi verfasserin aut In Dementia and Geriatric Cognitive Disorders Extra Karger Publishers, 2013 4(2014), 2, Seite 335-343 (DE-627)665673434 (DE-600)2621464-7 16645464 nnns volume:4 year:2014 number:2 pages:335-343 https://doi.org/10.1159/000363500 kostenfrei https://doaj.org/article/74df7ac1284b44a4a0a269f7a96aa969 kostenfrei http://www.karger.com/Article/FullText/363500 kostenfrei https://doaj.org/toc/1664-5464 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_2018 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 4 2014 2 335-343
language	English
source	In Dementia and Geriatric Cognitive Disorders Extra 4(2014), 2, Seite 335-343 volume:4 year:2014 number:2 pages:335-343
sourceStr	In Dementia and Geriatric Cognitive Disorders Extra 4(2014), 2, Seite 335-343 volume:4 year:2014 number:2 pages:335-343
format_phy_str_mv	Article
institution	findex.gbv.de
topic_facet	Dementia Agitation CMAI Cerebrospinal fluid (CSF) Dementia biomarkers Neurofibrillary tangles Behavioral and psychological symptoms in dementia (BPSD) Neurology. Diseases of the nervous system Geriatrics
isfreeaccess_bool	true
container_title	Dementia and Geriatric Cognitive Disorders Extra
authorswithroles_txt_mv	Victor Bloniecki @@aut@@ Dag Aarsland @@aut@@ Jeffrey Cummings @@aut@@ Kaj Blennow @@aut@@ Yvonne Freund-Levi @@aut@@
publishDateDaySort_date	2014-01-01T00:00:00Z
hierarchy_top_id	665673434
id	DOAJ019644310
language_de	englisch
fullrecord	<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000caa a22002652 4500</leader><controlfield tag="001">DOAJ019644310</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20230310111905.0</controlfield><controlfield tag="007">cr uuu---uuuuu</controlfield><controlfield tag="008">230226s2014 xx \|\|\|\|\|o 00\| \|\|eng c</controlfield><datafield tag="024" ind1="7" ind2=" "><subfield code="a">10.1159/000363500</subfield><subfield code="2">doi</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)DOAJ019644310</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-599)DOAJ74df7ac1284b44a4a0a269f7a96aa969</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="041" ind1=" " ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="050" ind1=" " ind2="0"><subfield code="a">RC346-429</subfield></datafield><datafield tag="050" ind1=" " ind2="0"><subfield code="a">RC952-954.6</subfield></datafield><datafield tag="100" ind1="0" ind2=" "><subfield code="a">Victor Bloniecki</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Agitation in Dementia: Relation to Core Cerebrospinal Fluid Biomarker Levels</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="c">2014</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">Text</subfield><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">Computermedien</subfield><subfield code="b">c</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">Online-Ressource</subfield><subfield code="b">cr</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">Background: The objective of this study was to examine the associations of agitation with the cerebrospinal fluid dementia biomarkers total-tau (T-tau), phosphorylated-tau (P-tau) and Aβ1-42. Methods: One hundred patients (mean age ± SD, 78.6 ± 7.5 years) with dementia and neuropsychiatric symptoms, of whom 67% were female, were included. Agitation was measured using the Cohen-Mansfield Agitation Inventory (CMAI; 46.5 ± 11.8 points). Results: Total CMAI correlated with T-tau [rs (31) = 0.36, p = 0.04] and P-tau [rs (31) = 0.35, p = 0.05] in patients with Alzheimer's disease (AD; n = 33) but not in the total dementia population (n = 95). Conclusions: Our results suggest that tau-mediated pathology including neurofibrillary tangles and the intensity of the disease process might be associated with agitation in AD.</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Dementia</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Agitation</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">CMAI</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Cerebrospinal fluid (CSF)</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Dementia biomarkers</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Neurofibrillary tangles</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Behavioral and psychological symptoms in dementia (BPSD)</subfield></datafield><datafield tag="653" ind1=" " ind2="0"><subfield code="a">Neurology. Diseases of the nervous system</subfield></datafield><datafield tag="653" ind1=" " ind2="0"><subfield code="a">Geriatrics</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Dag Aarsland</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Jeffrey Cummings</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Kaj Blennow</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Yvonne Freund-Levi</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="773" ind1="0" ind2="8"><subfield code="i">In</subfield><subfield code="t">Dementia and Geriatric Cognitive Disorders Extra</subfield><subfield code="d">Karger Publishers, 2013</subfield><subfield code="g">4(2014), 2, Seite 335-343</subfield><subfield code="w">(DE-627)665673434</subfield><subfield code="w">(DE-600)2621464-7</subfield><subfield code="x">16645464</subfield><subfield code="7">nnns</subfield></datafield><datafield tag="773" ind1="1" ind2="8"><subfield code="g">volume:4</subfield><subfield code="g">year:2014</subfield><subfield code="g">number:2</subfield><subfield code="g">pages:335-343</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">https://doi.org/10.1159/000363500</subfield><subfield code="z">kostenfrei</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">https://doaj.org/article/74df7ac1284b44a4a0a269f7a96aa969</subfield><subfield code="z">kostenfrei</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">http://www.karger.com/Article/FullText/363500</subfield><subfield code="z">kostenfrei</subfield></datafield><datafield tag="856" ind1="4" ind2="2"><subfield code="u">https://doaj.org/toc/1664-5464</subfield><subfield code="y">Journal toc</subfield><subfield code="z">kostenfrei</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_USEFLAG_A</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">SYSFLAG_A</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_DOAJ</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_20</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_22</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_23</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_24</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_31</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_39</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_40</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_60</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_62</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_63</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_65</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_69</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_73</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_74</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_95</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_105</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_110</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_151</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_161</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_170</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_206</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_213</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_230</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_285</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_293</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_602</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2014</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2018</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4012</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4037</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4112</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4125</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4126</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4249</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4305</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4306</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4307</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4313</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4322</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4323</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4324</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4325</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4338</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4367</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4700</subfield></datafield><datafield tag="951" ind1=" " ind2=" "><subfield code="a">AR</subfield></datafield><datafield tag="952" ind1=" " ind2=" "><subfield code="d">4</subfield><subfield code="j">2014</subfield><subfield code="e">2</subfield><subfield code="h">335-343</subfield></datafield></record></collection>
callnumber-first	R - Medicine
author	Victor Bloniecki
spellingShingle	Victor Bloniecki misc RC346-429 misc RC952-954.6 misc Dementia misc Agitation misc CMAI misc Cerebrospinal fluid (CSF) misc Dementia biomarkers misc Neurofibrillary tangles misc Behavioral and psychological symptoms in dementia (BPSD) misc Neurology. Diseases of the nervous system misc Geriatrics Agitation in Dementia: Relation to Core Cerebrospinal Fluid Biomarker Levels
authorStr	Victor Bloniecki
ppnlink_with_tag_str_mv	@@773@@(DE-627)665673434
format	electronic Article
delete_txt_mv	keep
author_role	aut aut aut aut aut
collection	DOAJ
remote_str	true
callnumber-label	RC346-429
illustrated	Not Illustrated
issn	16645464
topic_title	RC346-429 RC952-954.6 Agitation in Dementia: Relation to Core Cerebrospinal Fluid Biomarker Levels Dementia Agitation CMAI Cerebrospinal fluid (CSF) Dementia biomarkers Neurofibrillary tangles Behavioral and psychological symptoms in dementia (BPSD)
topic	misc RC346-429 misc RC952-954.6 misc Dementia misc Agitation misc CMAI misc Cerebrospinal fluid (CSF) misc Dementia biomarkers misc Neurofibrillary tangles misc Behavioral and psychological symptoms in dementia (BPSD) misc Neurology. Diseases of the nervous system misc Geriatrics
topic_unstemmed	misc RC346-429 misc RC952-954.6 misc Dementia misc Agitation misc CMAI misc Cerebrospinal fluid (CSF) misc Dementia biomarkers misc Neurofibrillary tangles misc Behavioral and psychological symptoms in dementia (BPSD) misc Neurology. Diseases of the nervous system misc Geriatrics
topic_browse	misc RC346-429 misc RC952-954.6 misc Dementia misc Agitation misc CMAI misc Cerebrospinal fluid (CSF) misc Dementia biomarkers misc Neurofibrillary tangles misc Behavioral and psychological symptoms in dementia (BPSD) misc Neurology. Diseases of the nervous system misc Geriatrics
format_facet	Elektronische Aufsätze Aufsätze Elektronische Ressource
format_main_str_mv	Text Zeitschrift/Artikel
carriertype_str_mv	cr
hierarchy_parent_title	Dementia and Geriatric Cognitive Disorders Extra
hierarchy_parent_id	665673434
hierarchy_top_title	Dementia and Geriatric Cognitive Disorders Extra
isfreeaccess_txt	true
familylinks_str_mv	(DE-627)665673434 (DE-600)2621464-7
title	Agitation in Dementia: Relation to Core Cerebrospinal Fluid Biomarker Levels
ctrlnum	(DE-627)DOAJ019644310 (DE-599)DOAJ74df7ac1284b44a4a0a269f7a96aa969
title_full	Agitation in Dementia: Relation to Core Cerebrospinal Fluid Biomarker Levels
author_sort	Victor Bloniecki
journal	Dementia and Geriatric Cognitive Disorders Extra
journalStr	Dementia and Geriatric Cognitive Disorders Extra
callnumber-first-code	R
lang_code	eng
isOA_bool	true
recordtype	marc
publishDateSort	2014
contenttype_str_mv	txt
container_start_page	335
author_browse	Victor Bloniecki Dag Aarsland Jeffrey Cummings Kaj Blennow Yvonne Freund-Levi
container_volume	4
class	RC346-429 RC952-954.6
format_se	Elektronische Aufsätze
author-letter	Victor Bloniecki
doi_str_mv	10.1159/000363500
author2-role	verfasserin
title_sort	agitation in dementia: relation to core cerebrospinal fluid biomarker levels
callnumber	RC346-429
title_auth	Agitation in Dementia: Relation to Core Cerebrospinal Fluid Biomarker Levels
abstract	Background: The objective of this study was to examine the associations of agitation with the cerebrospinal fluid dementia biomarkers total-tau (T-tau), phosphorylated-tau (P-tau) and Aβ1-42. Methods: One hundred patients (mean age ± SD, 78.6 ± 7.5 years) with dementia and neuropsychiatric symptoms, of whom 67% were female, were included. Agitation was measured using the Cohen-Mansfield Agitation Inventory (CMAI; 46.5 ± 11.8 points). Results: Total CMAI correlated with T-tau [rs (31) = 0.36, p = 0.04] and P-tau [rs (31) = 0.35, p = 0.05] in patients with Alzheimer's disease (AD; n = 33) but not in the total dementia population (n = 95). Conclusions: Our results suggest that tau-mediated pathology including neurofibrillary tangles and the intensity of the disease process might be associated with agitation in AD.
abstractGer	Background: The objective of this study was to examine the associations of agitation with the cerebrospinal fluid dementia biomarkers total-tau (T-tau), phosphorylated-tau (P-tau) and Aβ1-42. Methods: One hundred patients (mean age ± SD, 78.6 ± 7.5 years) with dementia and neuropsychiatric symptoms, of whom 67% were female, were included. Agitation was measured using the Cohen-Mansfield Agitation Inventory (CMAI; 46.5 ± 11.8 points). Results: Total CMAI correlated with T-tau [rs (31) = 0.36, p = 0.04] and P-tau [rs (31) = 0.35, p = 0.05] in patients with Alzheimer's disease (AD; n = 33) but not in the total dementia population (n = 95). Conclusions: Our results suggest that tau-mediated pathology including neurofibrillary tangles and the intensity of the disease process might be associated with agitation in AD.
abstract_unstemmed	Background: The objective of this study was to examine the associations of agitation with the cerebrospinal fluid dementia biomarkers total-tau (T-tau), phosphorylated-tau (P-tau) and Aβ1-42. Methods: One hundred patients (mean age ± SD, 78.6 ± 7.5 years) with dementia and neuropsychiatric symptoms, of whom 67% were female, were included. Agitation was measured using the Cohen-Mansfield Agitation Inventory (CMAI; 46.5 ± 11.8 points). Results: Total CMAI correlated with T-tau [rs (31) = 0.36, p = 0.04] and P-tau [rs (31) = 0.35, p = 0.05] in patients with Alzheimer's disease (AD; n = 33) but not in the total dementia population (n = 95). Conclusions: Our results suggest that tau-mediated pathology including neurofibrillary tangles and the intensity of the disease process might be associated with agitation in AD.
collection_details	GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_2018 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700
container_issue	2
title_short	Agitation in Dementia: Relation to Core Cerebrospinal Fluid Biomarker Levels
url	https://doi.org/10.1159/000363500 https://doaj.org/article/74df7ac1284b44a4a0a269f7a96aa969 http://www.karger.com/Article/FullText/363500 https://doaj.org/toc/1664-5464
remote_bool	true
author2	Dag Aarsland Jeffrey Cummings Kaj Blennow Yvonne Freund-Levi
author2Str	Dag Aarsland Jeffrey Cummings Kaj Blennow Yvonne Freund-Levi
ppnlink	665673434
callnumber-subject	RC - Internal Medicine
mediatype_str_mv	c
isOA_txt	true
hochschulschrift_bool	false
doi_str	10.1159/000363500
callnumber-a	RC346-429
up_date	2024-07-04T00:23:52.015Z
_version_	1803605908671954944
fullrecord_marcxml	<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000caa a22002652 4500</leader><controlfield tag="001">DOAJ019644310</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20230310111905.0</controlfield><controlfield tag="007">cr uuu---uuuuu</controlfield><controlfield tag="008">230226s2014 xx \|\|\|\|\|o 00\| \|\|eng c</controlfield><datafield tag="024" ind1="7" ind2=" "><subfield code="a">10.1159/000363500</subfield><subfield code="2">doi</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)DOAJ019644310</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-599)DOAJ74df7ac1284b44a4a0a269f7a96aa969</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="041" ind1=" " ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="050" ind1=" " ind2="0"><subfield code="a">RC346-429</subfield></datafield><datafield tag="050" ind1=" " ind2="0"><subfield code="a">RC952-954.6</subfield></datafield><datafield tag="100" ind1="0" ind2=" "><subfield code="a">Victor Bloniecki</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Agitation in Dementia: Relation to Core Cerebrospinal Fluid Biomarker Levels</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="c">2014</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">Text</subfield><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">Computermedien</subfield><subfield code="b">c</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">Online-Ressource</subfield><subfield code="b">cr</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">Background: The objective of this study was to examine the associations of agitation with the cerebrospinal fluid dementia biomarkers total-tau (T-tau), phosphorylated-tau (P-tau) and Aβ1-42. Methods: One hundred patients (mean age ± SD, 78.6 ± 7.5 years) with dementia and neuropsychiatric symptoms, of whom 67% were female, were included. Agitation was measured using the Cohen-Mansfield Agitation Inventory (CMAI; 46.5 ± 11.8 points). Results: Total CMAI correlated with T-tau [rs (31) = 0.36, p = 0.04] and P-tau [rs (31) = 0.35, p = 0.05] in patients with Alzheimer's disease (AD; n = 33) but not in the total dementia population (n = 95). Conclusions: Our results suggest that tau-mediated pathology including neurofibrillary tangles and the intensity of the disease process might be associated with agitation in AD.</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Dementia</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Agitation</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">CMAI</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Cerebrospinal fluid (CSF)</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Dementia biomarkers</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Neurofibrillary tangles</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Behavioral and psychological symptoms in dementia (BPSD)</subfield></datafield><datafield tag="653" ind1=" " ind2="0"><subfield code="a">Neurology. Diseases of the nervous system</subfield></datafield><datafield tag="653" ind1=" " ind2="0"><subfield code="a">Geriatrics</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Dag Aarsland</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Jeffrey Cummings</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Kaj Blennow</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Yvonne Freund-Levi</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="773" ind1="0" ind2="8"><subfield code="i">In</subfield><subfield code="t">Dementia and Geriatric Cognitive Disorders Extra</subfield><subfield code="d">Karger Publishers, 2013</subfield><subfield code="g">4(2014), 2, Seite 335-343</subfield><subfield code="w">(DE-627)665673434</subfield><subfield code="w">(DE-600)2621464-7</subfield><subfield code="x">16645464</subfield><subfield code="7">nnns</subfield></datafield><datafield tag="773" ind1="1" ind2="8"><subfield code="g">volume:4</subfield><subfield code="g">year:2014</subfield><subfield code="g">number:2</subfield><subfield code="g">pages:335-343</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">https://doi.org/10.1159/000363500</subfield><subfield code="z">kostenfrei</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">https://doaj.org/article/74df7ac1284b44a4a0a269f7a96aa969</subfield><subfield code="z">kostenfrei</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">http://www.karger.com/Article/FullText/363500</subfield><subfield code="z">kostenfrei</subfield></datafield><datafield tag="856" ind1="4" ind2="2"><subfield code="u">https://doaj.org/toc/1664-5464</subfield><subfield code="y">Journal toc</subfield><subfield code="z">kostenfrei</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_USEFLAG_A</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">SYSFLAG_A</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_DOAJ</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_20</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_22</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_23</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_24</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_31</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_39</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_40</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_60</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_62</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_63</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_65</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_69</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_73</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_74</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_95</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_105</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_110</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_151</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_161</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_170</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_206</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_213</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_230</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_285</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_293</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_602</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2014</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2018</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4012</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4037</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4112</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4125</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4126</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4249</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4305</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4306</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4307</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4313</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4322</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4323</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4324</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4325</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4338</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4367</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4700</subfield></datafield><datafield tag="951" ind1=" " ind2=" "><subfield code="a">AR</subfield></datafield><datafield tag="952" ind1=" " ind2=" "><subfield code="d">4</subfield><subfield code="j">2014</subfield><subfield code="e">2</subfield><subfield code="h">335-343</subfield></datafield></record></collection>
score	7.400198

Nicht das Richtige dabei?

Schreiben Sie uns!

Agitation in Dementia: Relation to Core Cerebrospinal Fluid Biomarker Levels

Nicht das Richtige dabei?

Zugang & Verfügbarkeit

Vorhandene Bände

Nicht das Richtige dabei?