FEATURES OF INTOXICATION SYNDROME IN PATIENTS WITH NONSPECIFIC SPINAL OSTEOMYELITIS
Background. Nonspecific spinal osteomyelitis (NSO) is a serious purulent-inflammatory disease, accompanied by high mortality and disability of patients. Aim. To study the characteristics of intoxication syndrome (IS) in patients with NSO and to assess the degree of influence of the activity of the i...
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Gespeichert in:
| Autor*in: |
Petukhov V. I. [verfasserIn] Kubrakov K. M. [verfasserIn] Kornilov A. V. [verfasserIn] Kuncevich M.V. [verfasserIn] |
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| Format: |
E-Artikel |
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| Sprache: |
bel ; Englisch ; Russisch |
| Erschienen: |
2019 |
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| Schlagwörter: |
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| Übergeordnetes Werk: |
In: Žurnal Grodnenskogo Gosudarstvennogo Medicinskogo Universiteta - Grodno State Medical University, 2018, 17(2019), 5, Seite 552-559 |
|---|---|
| Übergeordnetes Werk: |
volume:17 ; year:2019 ; number:5 ; pages:552-559 |
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Link aufrufen |
|---|
| DOI / URN: |
10.25298/2221-8785-2019-17-5-552-559 |
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| Katalog-ID: |
DOAJ021006709 |
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| 520 | |a Background. Nonspecific spinal osteomyelitis (NSO) is a serious purulent-inflammatory disease, accompanied by high mortality and disability of patients. Aim. To study the characteristics of intoxication syndrome (IS) in patients with NSO and to assess the degree of influence of the activity of the inflammatory process in the bone structures of the spinal column on the degree of intoxication. Material and methods. The neutrophil-lymphocyte ratio, leukocyte and hematological indices of intoxication, nuclear index of the degree of endotoxicosis, immunoreactivity index were studied in 46 patients with NSO. The relationship between the activity of the inflammatory process in the structures of the spinal column and the degree of IS has been studied. Results. The severity of IS in patients with complicated forms of NSO was significantly (p <0,05) higher than in patients with uncomplicated forms. The correlation between the degree of accumulation of radiopharmaceuticals in the structures of the spine and the severity of IS was not established (p< 0,05). A mathematical model was developed (Рχ2 = 0,0003), which makes it possible to suspect purulent complications in a patient with NSO by the severity of IS (sensitivity 65,38%, specificity 80%). Conclusion. The presence of IS makes it possible to suspect purulent complications in patients with NSO, which requires an extended diagnostic preoperative search. | ||
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10.25298/2221-8785-2019-17-5-552-559 doi (DE-627)DOAJ021006709 (DE-599)DOAJ5931764e0eb8456fb2abd9dab070de71 DE-627 ger DE-627 rakwb bel eng rus Petukhov V. I. verfasserin aut FEATURES OF INTOXICATION SYNDROME IN PATIENTS WITH NONSPECIFIC SPINAL OSTEOMYELITIS 2019 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background. Nonspecific spinal osteomyelitis (NSO) is a serious purulent-inflammatory disease, accompanied by high mortality and disability of patients. Aim. To study the characteristics of intoxication syndrome (IS) in patients with NSO and to assess the degree of influence of the activity of the inflammatory process in the bone structures of the spinal column on the degree of intoxication. Material and methods. The neutrophil-lymphocyte ratio, leukocyte and hematological indices of intoxication, nuclear index of the degree of endotoxicosis, immunoreactivity index were studied in 46 patients with NSO. The relationship between the activity of the inflammatory process in the structures of the spinal column and the degree of IS has been studied. Results. The severity of IS in patients with complicated forms of NSO was significantly (p <0,05) higher than in patients with uncomplicated forms. The correlation between the degree of accumulation of radiopharmaceuticals in the structures of the spine and the severity of IS was not established (p< 0,05). A mathematical model was developed (Рχ2 = 0,0003), which makes it possible to suspect purulent complications in a patient with NSO by the severity of IS (sensitivity 65,38%, specificity 80%). Conclusion. The presence of IS makes it possible to suspect purulent complications in patients with NSO, which requires an extended diagnostic preoperative search. spinal osteomyelitis intoxication osteoscintigraphy diagnostics Medicine R Kubrakov K. M. verfasserin aut Kornilov A. V. verfasserin aut Kuncevich M.V. verfasserin aut In Žurnal Grodnenskogo Gosudarstvennogo Medicinskogo Universiteta Grodno State Medical University, 2018 17(2019), 5, Seite 552-559 (DE-627)1760617040 24130109 nnns volume:17 year:2019 number:5 pages:552-559 https://doi.org/10.25298/2221-8785-2019-17-5-552-559 kostenfrei https://doaj.org/article/5931764e0eb8456fb2abd9dab070de71 kostenfrei http://journal-grsmu.by/index.php/ojs/article/view/2458 kostenfrei https://doaj.org/toc/2221-8785 Journal toc kostenfrei https://doaj.org/toc/2413-0109 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ AR 17 2019 5 552-559 |
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10.25298/2221-8785-2019-17-5-552-559 doi (DE-627)DOAJ021006709 (DE-599)DOAJ5931764e0eb8456fb2abd9dab070de71 DE-627 ger DE-627 rakwb bel eng rus Petukhov V. I. verfasserin aut FEATURES OF INTOXICATION SYNDROME IN PATIENTS WITH NONSPECIFIC SPINAL OSTEOMYELITIS 2019 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background. Nonspecific spinal osteomyelitis (NSO) is a serious purulent-inflammatory disease, accompanied by high mortality and disability of patients. Aim. To study the characteristics of intoxication syndrome (IS) in patients with NSO and to assess the degree of influence of the activity of the inflammatory process in the bone structures of the spinal column on the degree of intoxication. Material and methods. The neutrophil-lymphocyte ratio, leukocyte and hematological indices of intoxication, nuclear index of the degree of endotoxicosis, immunoreactivity index were studied in 46 patients with NSO. The relationship between the activity of the inflammatory process in the structures of the spinal column and the degree of IS has been studied. Results. The severity of IS in patients with complicated forms of NSO was significantly (p <0,05) higher than in patients with uncomplicated forms. The correlation between the degree of accumulation of radiopharmaceuticals in the structures of the spine and the severity of IS was not established (p< 0,05). A mathematical model was developed (Рχ2 = 0,0003), which makes it possible to suspect purulent complications in a patient with NSO by the severity of IS (sensitivity 65,38%, specificity 80%). Conclusion. The presence of IS makes it possible to suspect purulent complications in patients with NSO, which requires an extended diagnostic preoperative search. spinal osteomyelitis intoxication osteoscintigraphy diagnostics Medicine R Kubrakov K. M. verfasserin aut Kornilov A. V. verfasserin aut Kuncevich M.V. verfasserin aut In Žurnal Grodnenskogo Gosudarstvennogo Medicinskogo Universiteta Grodno State Medical University, 2018 17(2019), 5, Seite 552-559 (DE-627)1760617040 24130109 nnns volume:17 year:2019 number:5 pages:552-559 https://doi.org/10.25298/2221-8785-2019-17-5-552-559 kostenfrei https://doaj.org/article/5931764e0eb8456fb2abd9dab070de71 kostenfrei http://journal-grsmu.by/index.php/ojs/article/view/2458 kostenfrei https://doaj.org/toc/2221-8785 Journal toc kostenfrei https://doaj.org/toc/2413-0109 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ AR 17 2019 5 552-559 |
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10.25298/2221-8785-2019-17-5-552-559 doi (DE-627)DOAJ021006709 (DE-599)DOAJ5931764e0eb8456fb2abd9dab070de71 DE-627 ger DE-627 rakwb bel eng rus Petukhov V. I. verfasserin aut FEATURES OF INTOXICATION SYNDROME IN PATIENTS WITH NONSPECIFIC SPINAL OSTEOMYELITIS 2019 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background. Nonspecific spinal osteomyelitis (NSO) is a serious purulent-inflammatory disease, accompanied by high mortality and disability of patients. Aim. To study the characteristics of intoxication syndrome (IS) in patients with NSO and to assess the degree of influence of the activity of the inflammatory process in the bone structures of the spinal column on the degree of intoxication. Material and methods. The neutrophil-lymphocyte ratio, leukocyte and hematological indices of intoxication, nuclear index of the degree of endotoxicosis, immunoreactivity index were studied in 46 patients with NSO. The relationship between the activity of the inflammatory process in the structures of the spinal column and the degree of IS has been studied. Results. The severity of IS in patients with complicated forms of NSO was significantly (p <0,05) higher than in patients with uncomplicated forms. The correlation between the degree of accumulation of radiopharmaceuticals in the structures of the spine and the severity of IS was not established (p< 0,05). A mathematical model was developed (Рχ2 = 0,0003), which makes it possible to suspect purulent complications in a patient with NSO by the severity of IS (sensitivity 65,38%, specificity 80%). Conclusion. The presence of IS makes it possible to suspect purulent complications in patients with NSO, which requires an extended diagnostic preoperative search. spinal osteomyelitis intoxication osteoscintigraphy diagnostics Medicine R Kubrakov K. M. verfasserin aut Kornilov A. V. verfasserin aut Kuncevich M.V. verfasserin aut In Žurnal Grodnenskogo Gosudarstvennogo Medicinskogo Universiteta Grodno State Medical University, 2018 17(2019), 5, Seite 552-559 (DE-627)1760617040 24130109 nnns volume:17 year:2019 number:5 pages:552-559 https://doi.org/10.25298/2221-8785-2019-17-5-552-559 kostenfrei https://doaj.org/article/5931764e0eb8456fb2abd9dab070de71 kostenfrei http://journal-grsmu.by/index.php/ojs/article/view/2458 kostenfrei https://doaj.org/toc/2221-8785 Journal toc kostenfrei https://doaj.org/toc/2413-0109 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ AR 17 2019 5 552-559 |
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10.25298/2221-8785-2019-17-5-552-559 doi (DE-627)DOAJ021006709 (DE-599)DOAJ5931764e0eb8456fb2abd9dab070de71 DE-627 ger DE-627 rakwb bel eng rus Petukhov V. I. verfasserin aut FEATURES OF INTOXICATION SYNDROME IN PATIENTS WITH NONSPECIFIC SPINAL OSTEOMYELITIS 2019 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background. Nonspecific spinal osteomyelitis (NSO) is a serious purulent-inflammatory disease, accompanied by high mortality and disability of patients. Aim. To study the characteristics of intoxication syndrome (IS) in patients with NSO and to assess the degree of influence of the activity of the inflammatory process in the bone structures of the spinal column on the degree of intoxication. Material and methods. The neutrophil-lymphocyte ratio, leukocyte and hematological indices of intoxication, nuclear index of the degree of endotoxicosis, immunoreactivity index were studied in 46 patients with NSO. The relationship between the activity of the inflammatory process in the structures of the spinal column and the degree of IS has been studied. Results. The severity of IS in patients with complicated forms of NSO was significantly (p <0,05) higher than in patients with uncomplicated forms. The correlation between the degree of accumulation of radiopharmaceuticals in the structures of the spine and the severity of IS was not established (p< 0,05). A mathematical model was developed (Рχ2 = 0,0003), which makes it possible to suspect purulent complications in a patient with NSO by the severity of IS (sensitivity 65,38%, specificity 80%). Conclusion. The presence of IS makes it possible to suspect purulent complications in patients with NSO, which requires an extended diagnostic preoperative search. spinal osteomyelitis intoxication osteoscintigraphy diagnostics Medicine R Kubrakov K. M. verfasserin aut Kornilov A. V. verfasserin aut Kuncevich M.V. verfasserin aut In Žurnal Grodnenskogo Gosudarstvennogo Medicinskogo Universiteta Grodno State Medical University, 2018 17(2019), 5, Seite 552-559 (DE-627)1760617040 24130109 nnns volume:17 year:2019 number:5 pages:552-559 https://doi.org/10.25298/2221-8785-2019-17-5-552-559 kostenfrei https://doaj.org/article/5931764e0eb8456fb2abd9dab070de71 kostenfrei http://journal-grsmu.by/index.php/ojs/article/view/2458 kostenfrei https://doaj.org/toc/2221-8785 Journal toc kostenfrei https://doaj.org/toc/2413-0109 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ AR 17 2019 5 552-559 |
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FEATURES OF INTOXICATION SYNDROME IN PATIENTS WITH NONSPECIFIC SPINAL OSTEOMYELITIS |
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(DE-627)DOAJ021006709 (DE-599)DOAJ5931764e0eb8456fb2abd9dab070de71 |
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FEATURES OF INTOXICATION SYNDROME IN PATIENTS WITH NONSPECIFIC SPINAL OSTEOMYELITIS |
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Petukhov V. I. |
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Žurnal Grodnenskogo Gosudarstvennogo Medicinskogo Universiteta |
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Petukhov V. I. Kubrakov K. M. Kornilov A. V. Kuncevich M.V. |
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Petukhov V. I. |
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features of intoxication syndrome in patients with nonspecific spinal osteomyelitis |
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FEATURES OF INTOXICATION SYNDROME IN PATIENTS WITH NONSPECIFIC SPINAL OSTEOMYELITIS |
| abstract |
Background. Nonspecific spinal osteomyelitis (NSO) is a serious purulent-inflammatory disease, accompanied by high mortality and disability of patients. Aim. To study the characteristics of intoxication syndrome (IS) in patients with NSO and to assess the degree of influence of the activity of the inflammatory process in the bone structures of the spinal column on the degree of intoxication. Material and methods. The neutrophil-lymphocyte ratio, leukocyte and hematological indices of intoxication, nuclear index of the degree of endotoxicosis, immunoreactivity index were studied in 46 patients with NSO. The relationship between the activity of the inflammatory process in the structures of the spinal column and the degree of IS has been studied. Results. The severity of IS in patients with complicated forms of NSO was significantly (p <0,05) higher than in patients with uncomplicated forms. The correlation between the degree of accumulation of radiopharmaceuticals in the structures of the spine and the severity of IS was not established (p< 0,05). A mathematical model was developed (Рχ2 = 0,0003), which makes it possible to suspect purulent complications in a patient with NSO by the severity of IS (sensitivity 65,38%, specificity 80%). Conclusion. The presence of IS makes it possible to suspect purulent complications in patients with NSO, which requires an extended diagnostic preoperative search. |
| abstractGer |
Background. Nonspecific spinal osteomyelitis (NSO) is a serious purulent-inflammatory disease, accompanied by high mortality and disability of patients. Aim. To study the characteristics of intoxication syndrome (IS) in patients with NSO and to assess the degree of influence of the activity of the inflammatory process in the bone structures of the spinal column on the degree of intoxication. Material and methods. The neutrophil-lymphocyte ratio, leukocyte and hematological indices of intoxication, nuclear index of the degree of endotoxicosis, immunoreactivity index were studied in 46 patients with NSO. The relationship between the activity of the inflammatory process in the structures of the spinal column and the degree of IS has been studied. Results. The severity of IS in patients with complicated forms of NSO was significantly (p <0,05) higher than in patients with uncomplicated forms. The correlation between the degree of accumulation of radiopharmaceuticals in the structures of the spine and the severity of IS was not established (p< 0,05). A mathematical model was developed (Рχ2 = 0,0003), which makes it possible to suspect purulent complications in a patient with NSO by the severity of IS (sensitivity 65,38%, specificity 80%). Conclusion. The presence of IS makes it possible to suspect purulent complications in patients with NSO, which requires an extended diagnostic preoperative search. |
| abstract_unstemmed |
Background. Nonspecific spinal osteomyelitis (NSO) is a serious purulent-inflammatory disease, accompanied by high mortality and disability of patients. Aim. To study the characteristics of intoxication syndrome (IS) in patients with NSO and to assess the degree of influence of the activity of the inflammatory process in the bone structures of the spinal column on the degree of intoxication. Material and methods. The neutrophil-lymphocyte ratio, leukocyte and hematological indices of intoxication, nuclear index of the degree of endotoxicosis, immunoreactivity index were studied in 46 patients with NSO. The relationship between the activity of the inflammatory process in the structures of the spinal column and the degree of IS has been studied. Results. The severity of IS in patients with complicated forms of NSO was significantly (p <0,05) higher than in patients with uncomplicated forms. The correlation between the degree of accumulation of radiopharmaceuticals in the structures of the spine and the severity of IS was not established (p< 0,05). A mathematical model was developed (Рχ2 = 0,0003), which makes it possible to suspect purulent complications in a patient with NSO by the severity of IS (sensitivity 65,38%, specificity 80%). Conclusion. The presence of IS makes it possible to suspect purulent complications in patients with NSO, which requires an extended diagnostic preoperative search. |
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FEATURES OF INTOXICATION SYNDROME IN PATIENTS WITH NONSPECIFIC SPINAL OSTEOMYELITIS |
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https://doi.org/10.25298/2221-8785-2019-17-5-552-559 https://doaj.org/article/5931764e0eb8456fb2abd9dab070de71 http://journal-grsmu.by/index.php/ojs/article/view/2458 https://doaj.org/toc/2221-8785 https://doaj.org/toc/2413-0109 |
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