Effects of transcranial direct current stimulation (tDCS) on consolidation of fear memory

It has been shown that applying transcranial direct current stimulation (tDCS) over the dorsolateral prefrontal cortex (DLPFC) influences declarative memory processes. This study investigates the efficacy of tDCS on emotional memory consolidation, especially experimental fear conditioning. We applie...
Ausführliche Beschreibung

Gespeichert in:

Autor*in:	Manish eAsthana [verfasserIn] Katharina eNueckel [verfasserIn] Andreas eMühlberger [verfasserIn] Dorothea eNeueder [verfasserIn] Thomas ePolak [verfasserIn] Katharina eDomschke [verfasserIn] Jürgen eDeckert [verfasserIn] Martin J. Herrmann [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2013

Schlagwörter:	Fear conditioning transcranial direct current stimulation (tDCS) dorsolateral prefrontal cortex (DLPFC) skin conductance response (SCR) fear memory consolidation

Übergeordnetes Werk:	In: Frontiers in Psychiatry - Frontiers Media S.A., 2010, 4(2013)
Übergeordnetes Werk:	volume:4 ; year:2013

Links:	Link aufrufen Link aufrufen Link aufrufen Journal toc

DOI / URN:	10.3389/fpsyt.2013.00107

Katalog-ID:	DOAJ02139427X

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spelling	10.3389/fpsyt.2013.00107 doi (DE-627)DOAJ02139427X (DE-599)DOAJ8e5abe2c577f4670b91e8cc1e39c5ae6 DE-627 ger DE-627 rakwb eng RC435-571 Manish eAsthana verfasserin aut Effects of transcranial direct current stimulation (tDCS) on consolidation of fear memory 2013 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier It has been shown that applying transcranial direct current stimulation (tDCS) over the dorsolateral prefrontal cortex (DLPFC) influences declarative memory processes. This study investigates the efficacy of tDCS on emotional memory consolidation, especially experimental fear conditioning. We applied an auditory fear-conditioning paradigm; in which two differently colored squares (blue and yellow) were presented as conditioned stimuli (CS) and an auditory stimulus as unconditioned stimulus (UCS). Sixty-nine participants were randomly assigned into three groups: anodal, cathodal and sham stimulation. The participants of the two active groups (i.e., anodal and cathodal) received tDCS over the left DLPFC for 12 minutes after fear conditioning. The effect of fear conditioning and consolidation (24 hours later) was measured by assessing the skin conductance response (SCR) to the CS. The results provide evidence that cathodal stimulation of the left DLPFC leads to an inhibitory effect on fear memory consolidation compared to anodal and sham stimulation, as indicated by decreased SCRs to CS+ presentation during extinction training at day 2. In conclusion, current work suggests that cathodal stimulation interferes with processes of fear memory consolidation. Fear conditioning transcranial direct current stimulation (tDCS) dorsolateral prefrontal cortex (DLPFC) skin conductance response (SCR) fear memory consolidation Psychiatry Katharina eNueckel verfasserin aut Andreas eMühlberger verfasserin aut Dorothea eNeueder verfasserin aut Thomas ePolak verfasserin aut Katharina eDomschke verfasserin aut Jürgen eDeckert verfasserin aut Martin J. Herrmann verfasserin aut In Frontiers in Psychiatry Frontiers Media S.A., 2010 4(2013) (DE-627)631498796 (DE-600)2564218-2 16640640 nnns volume:4 year:2013 https://doi.org/10.3389/fpsyt.2013.00107 kostenfrei https://doaj.org/article/8e5abe2c577f4670b91e8cc1e39c5ae6 kostenfrei http://journal.frontiersin.org/Journal/10.3389/fpsyt.2013.00107/full kostenfrei https://doaj.org/toc/1664-0640 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 4 2013
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topic_facet	Fear conditioning transcranial direct current stimulation (tDCS) dorsolateral prefrontal cortex (DLPFC) skin conductance response (SCR) fear memory consolidation Psychiatry
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callnumber-first	R - Medicine
author	Manish eAsthana
spellingShingle	Manish eAsthana misc RC435-571 misc Fear conditioning misc transcranial direct current stimulation (tDCS) misc dorsolateral prefrontal cortex (DLPFC) misc skin conductance response (SCR) misc fear memory consolidation misc Psychiatry Effects of transcranial direct current stimulation (tDCS) on consolidation of fear memory
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topic_title	RC435-571 Effects of transcranial direct current stimulation (tDCS) on consolidation of fear memory Fear conditioning transcranial direct current stimulation (tDCS) dorsolateral prefrontal cortex (DLPFC) skin conductance response (SCR) fear memory consolidation
topic	misc RC435-571 misc Fear conditioning misc transcranial direct current stimulation (tDCS) misc dorsolateral prefrontal cortex (DLPFC) misc skin conductance response (SCR) misc fear memory consolidation misc Psychiatry
topic_unstemmed	misc RC435-571 misc Fear conditioning misc transcranial direct current stimulation (tDCS) misc dorsolateral prefrontal cortex (DLPFC) misc skin conductance response (SCR) misc fear memory consolidation misc Psychiatry
topic_browse	misc RC435-571 misc Fear conditioning misc transcranial direct current stimulation (tDCS) misc dorsolateral prefrontal cortex (DLPFC) misc skin conductance response (SCR) misc fear memory consolidation misc Psychiatry
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title	Effects of transcranial direct current stimulation (tDCS) on consolidation of fear memory
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title_full	Effects of transcranial direct current stimulation (tDCS) on consolidation of fear memory
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author_browse	Manish eAsthana Katharina eNueckel Andreas eMühlberger Dorothea eNeueder Thomas ePolak Katharina eDomschke Jürgen eDeckert Martin J. Herrmann
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title_sort	effects of transcranial direct current stimulation (tdcs) on consolidation of fear memory
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title_auth	Effects of transcranial direct current stimulation (tDCS) on consolidation of fear memory
abstract	It has been shown that applying transcranial direct current stimulation (tDCS) over the dorsolateral prefrontal cortex (DLPFC) influences declarative memory processes. This study investigates the efficacy of tDCS on emotional memory consolidation, especially experimental fear conditioning. We applied an auditory fear-conditioning paradigm; in which two differently colored squares (blue and yellow) were presented as conditioned stimuli (CS) and an auditory stimulus as unconditioned stimulus (UCS). Sixty-nine participants were randomly assigned into three groups: anodal, cathodal and sham stimulation. The participants of the two active groups (i.e., anodal and cathodal) received tDCS over the left DLPFC for 12 minutes after fear conditioning. The effect of fear conditioning and consolidation (24 hours later) was measured by assessing the skin conductance response (SCR) to the CS. The results provide evidence that cathodal stimulation of the left DLPFC leads to an inhibitory effect on fear memory consolidation compared to anodal and sham stimulation, as indicated by decreased SCRs to CS+ presentation during extinction training at day 2. In conclusion, current work suggests that cathodal stimulation interferes with processes of fear memory consolidation.
abstractGer	It has been shown that applying transcranial direct current stimulation (tDCS) over the dorsolateral prefrontal cortex (DLPFC) influences declarative memory processes. This study investigates the efficacy of tDCS on emotional memory consolidation, especially experimental fear conditioning. We applied an auditory fear-conditioning paradigm; in which two differently colored squares (blue and yellow) were presented as conditioned stimuli (CS) and an auditory stimulus as unconditioned stimulus (UCS). Sixty-nine participants were randomly assigned into three groups: anodal, cathodal and sham stimulation. The participants of the two active groups (i.e., anodal and cathodal) received tDCS over the left DLPFC for 12 minutes after fear conditioning. The effect of fear conditioning and consolidation (24 hours later) was measured by assessing the skin conductance response (SCR) to the CS. The results provide evidence that cathodal stimulation of the left DLPFC leads to an inhibitory effect on fear memory consolidation compared to anodal and sham stimulation, as indicated by decreased SCRs to CS+ presentation during extinction training at day 2. In conclusion, current work suggests that cathodal stimulation interferes with processes of fear memory consolidation.
abstract_unstemmed	It has been shown that applying transcranial direct current stimulation (tDCS) over the dorsolateral prefrontal cortex (DLPFC) influences declarative memory processes. This study investigates the efficacy of tDCS on emotional memory consolidation, especially experimental fear conditioning. We applied an auditory fear-conditioning paradigm; in which two differently colored squares (blue and yellow) were presented as conditioned stimuli (CS) and an auditory stimulus as unconditioned stimulus (UCS). Sixty-nine participants were randomly assigned into three groups: anodal, cathodal and sham stimulation. The participants of the two active groups (i.e., anodal and cathodal) received tDCS over the left DLPFC for 12 minutes after fear conditioning. The effect of fear conditioning and consolidation (24 hours later) was measured by assessing the skin conductance response (SCR) to the CS. The results provide evidence that cathodal stimulation of the left DLPFC leads to an inhibitory effect on fear memory consolidation compared to anodal and sham stimulation, as indicated by decreased SCRs to CS+ presentation during extinction training at day 2. In conclusion, current work suggests that cathodal stimulation interferes with processes of fear memory consolidation.
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title_short	Effects of transcranial direct current stimulation (tDCS) on consolidation of fear memory
url	https://doi.org/10.3389/fpsyt.2013.00107 https://doaj.org/article/8e5abe2c577f4670b91e8cc1e39c5ae6 http://journal.frontiersin.org/Journal/10.3389/fpsyt.2013.00107/full https://doaj.org/toc/1664-0640
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author2	Katharina eNueckel Andreas eMühlberger Dorothea eNeueder Thomas ePolak Katharina eDomschke Jürgen eDeckert Martin J. Herrmann
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up_date	2024-07-03T20:37:24.468Z
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Effects of transcranial direct current stimulation (tDCS) on consolidation of fear memory

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