Plasmodium falciparum 7G8 challenge provides conservative prediction of efficacy of PfNF54-based PfSPZ Vaccine in Africa

Here the authors show that controlled human malaria infection with a Brazilian parasite highly divergent from vaccine and West African field strains can provide estimates of vaccine efficacy in Mali, and could replace field testing, streamlining vaccine development.

Gespeichert in:

Autor*in:	Joana C. Silva [verfasserIn] Ankit Dwivedi [verfasserIn] Kara A. Moser [verfasserIn] Mahamadou S. Sissoko [verfasserIn] Judith E. Epstein [verfasserIn] Sara A. Healy [verfasserIn] Kirsten E. Lyke [verfasserIn] Benjamin Mordmüller [verfasserIn] Peter G. Kremsner [verfasserIn] Patrick E. Duffy [verfasserIn] Tooba Murshedkar [verfasserIn] B. Kim Lee Sim [verfasserIn] Thomas L. Richie [verfasserIn] Stephen L. Hoffman [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2022

Übergeordnetes Werk:	In: Nature Communications - Nature Portfolio, 2016, 13(2022), 1, Seite 9
Übergeordnetes Werk:	volume:13 ; year:2022 ; number:1 ; pages:9

Links:	Link aufrufen Link aufrufen Link aufrufen Journal toc

DOI / URN:	10.1038/s41467-022-30882-8

Katalog-ID:	DOAJ021444099

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spelling	10.1038/s41467-022-30882-8 doi (DE-627)DOAJ021444099 (DE-599)DOAJ8adef3faef374367ad0d7275f5f65245 DE-627 ger DE-627 rakwb eng Joana C. Silva verfasserin aut Plasmodium falciparum 7G8 challenge provides conservative prediction of efficacy of PfNF54-based PfSPZ Vaccine in Africa 2022 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Here the authors show that controlled human malaria infection with a Brazilian parasite highly divergent from vaccine and West African field strains can provide estimates of vaccine efficacy in Mali, and could replace field testing, streamlining vaccine development. Science Q Ankit Dwivedi verfasserin aut Kara A. Moser verfasserin aut Mahamadou S. Sissoko verfasserin aut Judith E. Epstein verfasserin aut Sara A. Healy verfasserin aut Kirsten E. Lyke verfasserin aut Benjamin Mordmüller verfasserin aut Peter G. Kremsner verfasserin aut Patrick E. Duffy verfasserin aut Tooba Murshedkar verfasserin aut B. Kim Lee Sim verfasserin aut Thomas L. Richie verfasserin aut Stephen L. Hoffman verfasserin aut In Nature Communications Nature Portfolio, 2016 13(2022), 1, Seite 9 (DE-627)626457688 (DE-600)2553671-0 20411723 nnns volume:13 year:2022 number:1 pages:9 https://doi.org/10.1038/s41467-022-30882-8 kostenfrei https://doaj.org/article/8adef3faef374367ad0d7275f5f65245 kostenfrei https://doi.org/10.1038/s41467-022-30882-8 kostenfrei https://doaj.org/toc/2041-1723 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_171 GBV_ILN_211 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_2110 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 13 2022 1 9
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author	Joana C. Silva
spellingShingle	Joana C. Silva misc Science misc Q Plasmodium falciparum 7G8 challenge provides conservative prediction of efficacy of PfNF54-based PfSPZ Vaccine in Africa
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topic_title	Plasmodium falciparum 7G8 challenge provides conservative prediction of efficacy of PfNF54-based PfSPZ Vaccine in Africa
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title	Plasmodium falciparum 7G8 challenge provides conservative prediction of efficacy of PfNF54-based PfSPZ Vaccine in Africa
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title_full	Plasmodium falciparum 7G8 challenge provides conservative prediction of efficacy of PfNF54-based PfSPZ Vaccine in Africa
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author_browse	Joana C. Silva Ankit Dwivedi Kara A. Moser Mahamadou S. Sissoko Judith E. Epstein Sara A. Healy Kirsten E. Lyke Benjamin Mordmüller Peter G. Kremsner Patrick E. Duffy Tooba Murshedkar B. Kim Lee Sim Thomas L. Richie Stephen L. Hoffman
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title_sort	plasmodium falciparum 7g8 challenge provides conservative prediction of efficacy of pfnf54-based pfspz vaccine in africa
title_auth	Plasmodium falciparum 7G8 challenge provides conservative prediction of efficacy of PfNF54-based PfSPZ Vaccine in Africa
abstract	Here the authors show that controlled human malaria infection with a Brazilian parasite highly divergent from vaccine and West African field strains can provide estimates of vaccine efficacy in Mali, and could replace field testing, streamlining vaccine development.
abstractGer	Here the authors show that controlled human malaria infection with a Brazilian parasite highly divergent from vaccine and West African field strains can provide estimates of vaccine efficacy in Mali, and could replace field testing, streamlining vaccine development.
abstract_unstemmed	Here the authors show that controlled human malaria infection with a Brazilian parasite highly divergent from vaccine and West African field strains can provide estimates of vaccine efficacy in Mali, and could replace field testing, streamlining vaccine development.
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title_short	Plasmodium falciparum 7G8 challenge provides conservative prediction of efficacy of PfNF54-based PfSPZ Vaccine in Africa
url	https://doi.org/10.1038/s41467-022-30882-8 https://doaj.org/article/8adef3faef374367ad0d7275f5f65245 https://doaj.org/toc/2041-1723
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