Comparison of the effect of propofol and isoflurane on hemodynamic parameters and stress response hormones during Laparoscopic Cholecystectomy surgery

Background and Aims: General anesthesia induces endocrine, immunologic, and metabolic responses. Anesthetic drugs affect endocrine system by changing the level of stress hormones and hemodynamic of the patient. The purpose of this study was to compare the effects of propofol and isoflurane on hemody...
Ausführliche Beschreibung

Gespeichert in:

Autor*in:	Ali Ghomeishi [verfasserIn] Ahmad Reza Mohtadi [verfasserIn] Kaveh Behaeen [verfasserIn] Sholeh Nesioonpour [verfasserIn] Elham Sheida Golbad [verfasserIn] Nima Bakhtiari [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2022

Schlagwörter:	hemodynamic parameters isoflurane laparoscopic cholecystectomy propofol stress hormones

Übergeordnetes Werk:	In: Journal of Anaesthesiology Clinical Pharmacology - Wolters Kluwer Medknow Publications, 2006, 38(2022), 1, Seite 137-142
Übergeordnetes Werk:	volume:38 ; year:2022 ; number:1 ; pages:137-142

Links:	Link aufrufen Link aufrufen Link aufrufen Journal toc

DOI / URN:	10.4103/joacp.JOACP_146_19

Katalog-ID:	DOAJ021605947

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520			\|a Background and Aims: General anesthesia induces endocrine, immunologic, and metabolic responses. Anesthetic drugs affect endocrine system by changing the level of stress hormones and hemodynamic of the patient. The purpose of this study was to compare the effects of propofol and isoflurane on hemodynamic parameters and stress-induced hormones in laparoscopic cholecystectomy (LC) surgery. Material and Methods: Seventy patients of elective LC were included in this study. Patients were randomly divided into two equal groups of 35 patients; group P received propofol (70–120 μg/kg/min) and group I received isoflurane (mac: 1.28%) as anesthesia maintenance. The following parameters were monitored, checked, and recorded from preanesthesia period to 10 min after PACU entry according to a planned method: hemodynamic parameters (heart rate and mean atrial pressure), level of blood sugar, and serum epinephrine level. Results: Heart rate and mean atrial pressure changes did not show significant differences between the two groups in all stage (P < 0.05), but isoflurane group tolerated lower fluctuating changes. Blood glucose and serum epinephrine level rise in the isoflurane group were significantly higher than the propofol group (P < 0.05). Conclusion: Maintenance anesthesia by inhalation gas base on isoflurane has not shown a significant difference with total intravenous anesthesia base on propofol on hemodynamic parameter. However, propofol has a consistent effect on decreasing stress hormone and suggested for LC surgery.
650		4	\|a hemodynamic parameters
650		4	\|a isoflurane
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650		4	\|a stress hormones
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700	0		\|a Nima Bakhtiari \|e verfasserin \|4 aut
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allfields	10.4103/joacp.JOACP_146_19 doi (DE-627)DOAJ021605947 (DE-599)DOAJ961713570a894ef38e85bef88212b918 DE-627 ger DE-627 rakwb eng RD78.3-87.3 RS1-441 Ali Ghomeishi verfasserin aut Comparison of the effect of propofol and isoflurane on hemodynamic parameters and stress response hormones during Laparoscopic Cholecystectomy surgery 2022 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background and Aims: General anesthesia induces endocrine, immunologic, and metabolic responses. Anesthetic drugs affect endocrine system by changing the level of stress hormones and hemodynamic of the patient. The purpose of this study was to compare the effects of propofol and isoflurane on hemodynamic parameters and stress-induced hormones in laparoscopic cholecystectomy (LC) surgery. Material and Methods: Seventy patients of elective LC were included in this study. Patients were randomly divided into two equal groups of 35 patients; group P received propofol (70–120 μg/kg/min) and group I received isoflurane (mac: 1.28%) as anesthesia maintenance. The following parameters were monitored, checked, and recorded from preanesthesia period to 10 min after PACU entry according to a planned method: hemodynamic parameters (heart rate and mean atrial pressure), level of blood sugar, and serum epinephrine level. Results: Heart rate and mean atrial pressure changes did not show significant differences between the two groups in all stage (P < 0.05), but isoflurane group tolerated lower fluctuating changes. Blood glucose and serum epinephrine level rise in the isoflurane group were significantly higher than the propofol group (P < 0.05). Conclusion: Maintenance anesthesia by inhalation gas base on isoflurane has not shown a significant difference with total intravenous anesthesia base on propofol on hemodynamic parameter. However, propofol has a consistent effect on decreasing stress hormone and suggested for LC surgery. hemodynamic parameters isoflurane laparoscopic cholecystectomy propofol stress hormones Anesthesiology Pharmacy and materia medica Ahmad Reza Mohtadi verfasserin aut Kaveh Behaeen verfasserin aut Sholeh Nesioonpour verfasserin aut Elham Sheida Golbad verfasserin aut Nima Bakhtiari verfasserin aut In Journal of Anaesthesiology Clinical Pharmacology Wolters Kluwer Medknow Publications, 2006 38(2022), 1, Seite 137-142 (DE-627)518957225 (DE-600)2253976-1 22312730 nnns volume:38 year:2022 number:1 pages:137-142 https://doi.org/10.4103/joacp.JOACP_146_19 kostenfrei https://doaj.org/article/961713570a894ef38e85bef88212b918 kostenfrei http://www.joacp.org/article.asp?issn=0970-9185;year=2022;volume=38;issue=1;spage=137;epage=142;aulast=Ghomeishi kostenfrei https://doaj.org/toc/0970-9185 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 38 2022 1 137-142
spelling	10.4103/joacp.JOACP_146_19 doi (DE-627)DOAJ021605947 (DE-599)DOAJ961713570a894ef38e85bef88212b918 DE-627 ger DE-627 rakwb eng RD78.3-87.3 RS1-441 Ali Ghomeishi verfasserin aut Comparison of the effect of propofol and isoflurane on hemodynamic parameters and stress response hormones during Laparoscopic Cholecystectomy surgery 2022 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background and Aims: General anesthesia induces endocrine, immunologic, and metabolic responses. Anesthetic drugs affect endocrine system by changing the level of stress hormones and hemodynamic of the patient. The purpose of this study was to compare the effects of propofol and isoflurane on hemodynamic parameters and stress-induced hormones in laparoscopic cholecystectomy (LC) surgery. Material and Methods: Seventy patients of elective LC were included in this study. Patients were randomly divided into two equal groups of 35 patients; group P received propofol (70–120 μg/kg/min) and group I received isoflurane (mac: 1.28%) as anesthesia maintenance. The following parameters were monitored, checked, and recorded from preanesthesia period to 10 min after PACU entry according to a planned method: hemodynamic parameters (heart rate and mean atrial pressure), level of blood sugar, and serum epinephrine level. Results: Heart rate and mean atrial pressure changes did not show significant differences between the two groups in all stage (P < 0.05), but isoflurane group tolerated lower fluctuating changes. Blood glucose and serum epinephrine level rise in the isoflurane group were significantly higher than the propofol group (P < 0.05). Conclusion: Maintenance anesthesia by inhalation gas base on isoflurane has not shown a significant difference with total intravenous anesthesia base on propofol on hemodynamic parameter. However, propofol has a consistent effect on decreasing stress hormone and suggested for LC surgery. hemodynamic parameters isoflurane laparoscopic cholecystectomy propofol stress hormones Anesthesiology Pharmacy and materia medica Ahmad Reza Mohtadi verfasserin aut Kaveh Behaeen verfasserin aut Sholeh Nesioonpour verfasserin aut Elham Sheida Golbad verfasserin aut Nima Bakhtiari verfasserin aut In Journal of Anaesthesiology Clinical Pharmacology Wolters Kluwer Medknow Publications, 2006 38(2022), 1, Seite 137-142 (DE-627)518957225 (DE-600)2253976-1 22312730 nnns volume:38 year:2022 number:1 pages:137-142 https://doi.org/10.4103/joacp.JOACP_146_19 kostenfrei https://doaj.org/article/961713570a894ef38e85bef88212b918 kostenfrei http://www.joacp.org/article.asp?issn=0970-9185;year=2022;volume=38;issue=1;spage=137;epage=142;aulast=Ghomeishi kostenfrei https://doaj.org/toc/0970-9185 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 38 2022 1 137-142
allfields_unstemmed	10.4103/joacp.JOACP_146_19 doi (DE-627)DOAJ021605947 (DE-599)DOAJ961713570a894ef38e85bef88212b918 DE-627 ger DE-627 rakwb eng RD78.3-87.3 RS1-441 Ali Ghomeishi verfasserin aut Comparison of the effect of propofol and isoflurane on hemodynamic parameters and stress response hormones during Laparoscopic Cholecystectomy surgery 2022 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background and Aims: General anesthesia induces endocrine, immunologic, and metabolic responses. Anesthetic drugs affect endocrine system by changing the level of stress hormones and hemodynamic of the patient. The purpose of this study was to compare the effects of propofol and isoflurane on hemodynamic parameters and stress-induced hormones in laparoscopic cholecystectomy (LC) surgery. Material and Methods: Seventy patients of elective LC were included in this study. Patients were randomly divided into two equal groups of 35 patients; group P received propofol (70–120 μg/kg/min) and group I received isoflurane (mac: 1.28%) as anesthesia maintenance. The following parameters were monitored, checked, and recorded from preanesthesia period to 10 min after PACU entry according to a planned method: hemodynamic parameters (heart rate and mean atrial pressure), level of blood sugar, and serum epinephrine level. Results: Heart rate and mean atrial pressure changes did not show significant differences between the two groups in all stage (P < 0.05), but isoflurane group tolerated lower fluctuating changes. Blood glucose and serum epinephrine level rise in the isoflurane group were significantly higher than the propofol group (P < 0.05). Conclusion: Maintenance anesthesia by inhalation gas base on isoflurane has not shown a significant difference with total intravenous anesthesia base on propofol on hemodynamic parameter. However, propofol has a consistent effect on decreasing stress hormone and suggested for LC surgery. hemodynamic parameters isoflurane laparoscopic cholecystectomy propofol stress hormones Anesthesiology Pharmacy and materia medica Ahmad Reza Mohtadi verfasserin aut Kaveh Behaeen verfasserin aut Sholeh Nesioonpour verfasserin aut Elham Sheida Golbad verfasserin aut Nima Bakhtiari verfasserin aut In Journal of Anaesthesiology Clinical Pharmacology Wolters Kluwer Medknow Publications, 2006 38(2022), 1, Seite 137-142 (DE-627)518957225 (DE-600)2253976-1 22312730 nnns volume:38 year:2022 number:1 pages:137-142 https://doi.org/10.4103/joacp.JOACP_146_19 kostenfrei https://doaj.org/article/961713570a894ef38e85bef88212b918 kostenfrei http://www.joacp.org/article.asp?issn=0970-9185;year=2022;volume=38;issue=1;spage=137;epage=142;aulast=Ghomeishi kostenfrei https://doaj.org/toc/0970-9185 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 38 2022 1 137-142
allfieldsGer	10.4103/joacp.JOACP_146_19 doi (DE-627)DOAJ021605947 (DE-599)DOAJ961713570a894ef38e85bef88212b918 DE-627 ger DE-627 rakwb eng RD78.3-87.3 RS1-441 Ali Ghomeishi verfasserin aut Comparison of the effect of propofol and isoflurane on hemodynamic parameters and stress response hormones during Laparoscopic Cholecystectomy surgery 2022 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background and Aims: General anesthesia induces endocrine, immunologic, and metabolic responses. Anesthetic drugs affect endocrine system by changing the level of stress hormones and hemodynamic of the patient. The purpose of this study was to compare the effects of propofol and isoflurane on hemodynamic parameters and stress-induced hormones in laparoscopic cholecystectomy (LC) surgery. Material and Methods: Seventy patients of elective LC were included in this study. Patients were randomly divided into two equal groups of 35 patients; group P received propofol (70–120 μg/kg/min) and group I received isoflurane (mac: 1.28%) as anesthesia maintenance. The following parameters were monitored, checked, and recorded from preanesthesia period to 10 min after PACU entry according to a planned method: hemodynamic parameters (heart rate and mean atrial pressure), level of blood sugar, and serum epinephrine level. Results: Heart rate and mean atrial pressure changes did not show significant differences between the two groups in all stage (P < 0.05), but isoflurane group tolerated lower fluctuating changes. Blood glucose and serum epinephrine level rise in the isoflurane group were significantly higher than the propofol group (P < 0.05). Conclusion: Maintenance anesthesia by inhalation gas base on isoflurane has not shown a significant difference with total intravenous anesthesia base on propofol on hemodynamic parameter. However, propofol has a consistent effect on decreasing stress hormone and suggested for LC surgery. hemodynamic parameters isoflurane laparoscopic cholecystectomy propofol stress hormones Anesthesiology Pharmacy and materia medica Ahmad Reza Mohtadi verfasserin aut Kaveh Behaeen verfasserin aut Sholeh Nesioonpour verfasserin aut Elham Sheida Golbad verfasserin aut Nima Bakhtiari verfasserin aut In Journal of Anaesthesiology Clinical Pharmacology Wolters Kluwer Medknow Publications, 2006 38(2022), 1, Seite 137-142 (DE-627)518957225 (DE-600)2253976-1 22312730 nnns volume:38 year:2022 number:1 pages:137-142 https://doi.org/10.4103/joacp.JOACP_146_19 kostenfrei https://doaj.org/article/961713570a894ef38e85bef88212b918 kostenfrei http://www.joacp.org/article.asp?issn=0970-9185;year=2022;volume=38;issue=1;spage=137;epage=142;aulast=Ghomeishi kostenfrei https://doaj.org/toc/0970-9185 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 38 2022 1 137-142
allfieldsSound	10.4103/joacp.JOACP_146_19 doi (DE-627)DOAJ021605947 (DE-599)DOAJ961713570a894ef38e85bef88212b918 DE-627 ger DE-627 rakwb eng RD78.3-87.3 RS1-441 Ali Ghomeishi verfasserin aut Comparison of the effect of propofol and isoflurane on hemodynamic parameters and stress response hormones during Laparoscopic Cholecystectomy surgery 2022 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background and Aims: General anesthesia induces endocrine, immunologic, and metabolic responses. Anesthetic drugs affect endocrine system by changing the level of stress hormones and hemodynamic of the patient. The purpose of this study was to compare the effects of propofol and isoflurane on hemodynamic parameters and stress-induced hormones in laparoscopic cholecystectomy (LC) surgery. Material and Methods: Seventy patients of elective LC were included in this study. Patients were randomly divided into two equal groups of 35 patients; group P received propofol (70–120 μg/kg/min) and group I received isoflurane (mac: 1.28%) as anesthesia maintenance. The following parameters were monitored, checked, and recorded from preanesthesia period to 10 min after PACU entry according to a planned method: hemodynamic parameters (heart rate and mean atrial pressure), level of blood sugar, and serum epinephrine level. Results: Heart rate and mean atrial pressure changes did not show significant differences between the two groups in all stage (P < 0.05), but isoflurane group tolerated lower fluctuating changes. Blood glucose and serum epinephrine level rise in the isoflurane group were significantly higher than the propofol group (P < 0.05). Conclusion: Maintenance anesthesia by inhalation gas base on isoflurane has not shown a significant difference with total intravenous anesthesia base on propofol on hemodynamic parameter. However, propofol has a consistent effect on decreasing stress hormone and suggested for LC surgery. hemodynamic parameters isoflurane laparoscopic cholecystectomy propofol stress hormones Anesthesiology Pharmacy and materia medica Ahmad Reza Mohtadi verfasserin aut Kaveh Behaeen verfasserin aut Sholeh Nesioonpour verfasserin aut Elham Sheida Golbad verfasserin aut Nima Bakhtiari verfasserin aut In Journal of Anaesthesiology Clinical Pharmacology Wolters Kluwer Medknow Publications, 2006 38(2022), 1, Seite 137-142 (DE-627)518957225 (DE-600)2253976-1 22312730 nnns volume:38 year:2022 number:1 pages:137-142 https://doi.org/10.4103/joacp.JOACP_146_19 kostenfrei https://doaj.org/article/961713570a894ef38e85bef88212b918 kostenfrei http://www.joacp.org/article.asp?issn=0970-9185;year=2022;volume=38;issue=1;spage=137;epage=142;aulast=Ghomeishi kostenfrei https://doaj.org/toc/0970-9185 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 38 2022 1 137-142
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authorswithroles_txt_mv	Ali Ghomeishi @@aut@@ Ahmad Reza Mohtadi @@aut@@ Kaveh Behaeen @@aut@@ Sholeh Nesioonpour @@aut@@ Elham Sheida Golbad @@aut@@ Nima Bakhtiari @@aut@@
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callnumber-first	R - Medicine
author	Ali Ghomeishi
spellingShingle	Ali Ghomeishi misc RD78.3-87.3 misc RS1-441 misc hemodynamic parameters misc isoflurane misc laparoscopic cholecystectomy misc propofol misc stress hormones misc Anesthesiology misc Pharmacy and materia medica Comparison of the effect of propofol and isoflurane on hemodynamic parameters and stress response hormones during Laparoscopic Cholecystectomy surgery
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topic_title	RD78.3-87.3 RS1-441 Comparison of the effect of propofol and isoflurane on hemodynamic parameters and stress response hormones during Laparoscopic Cholecystectomy surgery hemodynamic parameters isoflurane laparoscopic cholecystectomy propofol stress hormones
topic	misc RD78.3-87.3 misc RS1-441 misc hemodynamic parameters misc isoflurane misc laparoscopic cholecystectomy misc propofol misc stress hormones misc Anesthesiology misc Pharmacy and materia medica
topic_unstemmed	misc RD78.3-87.3 misc RS1-441 misc hemodynamic parameters misc isoflurane misc laparoscopic cholecystectomy misc propofol misc stress hormones misc Anesthesiology misc Pharmacy and materia medica
topic_browse	misc RD78.3-87.3 misc RS1-441 misc hemodynamic parameters misc isoflurane misc laparoscopic cholecystectomy misc propofol misc stress hormones misc Anesthesiology misc Pharmacy and materia medica
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title	Comparison of the effect of propofol and isoflurane on hemodynamic parameters and stress response hormones during Laparoscopic Cholecystectomy surgery
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title_full	Comparison of the effect of propofol and isoflurane on hemodynamic parameters and stress response hormones during Laparoscopic Cholecystectomy surgery
author_sort	Ali Ghomeishi
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title_sort	comparison of the effect of propofol and isoflurane on hemodynamic parameters and stress response hormones during laparoscopic cholecystectomy surgery
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title_auth	Comparison of the effect of propofol and isoflurane on hemodynamic parameters and stress response hormones during Laparoscopic Cholecystectomy surgery
abstract	Background and Aims: General anesthesia induces endocrine, immunologic, and metabolic responses. Anesthetic drugs affect endocrine system by changing the level of stress hormones and hemodynamic of the patient. The purpose of this study was to compare the effects of propofol and isoflurane on hemodynamic parameters and stress-induced hormones in laparoscopic cholecystectomy (LC) surgery. Material and Methods: Seventy patients of elective LC were included in this study. Patients were randomly divided into two equal groups of 35 patients; group P received propofol (70–120 μg/kg/min) and group I received isoflurane (mac: 1.28%) as anesthesia maintenance. The following parameters were monitored, checked, and recorded from preanesthesia period to 10 min after PACU entry according to a planned method: hemodynamic parameters (heart rate and mean atrial pressure), level of blood sugar, and serum epinephrine level. Results: Heart rate and mean atrial pressure changes did not show significant differences between the two groups in all stage (P < 0.05), but isoflurane group tolerated lower fluctuating changes. Blood glucose and serum epinephrine level rise in the isoflurane group were significantly higher than the propofol group (P < 0.05). Conclusion: Maintenance anesthesia by inhalation gas base on isoflurane has not shown a significant difference with total intravenous anesthesia base on propofol on hemodynamic parameter. However, propofol has a consistent effect on decreasing stress hormone and suggested for LC surgery.
abstractGer	Background and Aims: General anesthesia induces endocrine, immunologic, and metabolic responses. Anesthetic drugs affect endocrine system by changing the level of stress hormones and hemodynamic of the patient. The purpose of this study was to compare the effects of propofol and isoflurane on hemodynamic parameters and stress-induced hormones in laparoscopic cholecystectomy (LC) surgery. Material and Methods: Seventy patients of elective LC were included in this study. Patients were randomly divided into two equal groups of 35 patients; group P received propofol (70–120 μg/kg/min) and group I received isoflurane (mac: 1.28%) as anesthesia maintenance. The following parameters were monitored, checked, and recorded from preanesthesia period to 10 min after PACU entry according to a planned method: hemodynamic parameters (heart rate and mean atrial pressure), level of blood sugar, and serum epinephrine level. Results: Heart rate and mean atrial pressure changes did not show significant differences between the two groups in all stage (P < 0.05), but isoflurane group tolerated lower fluctuating changes. Blood glucose and serum epinephrine level rise in the isoflurane group were significantly higher than the propofol group (P < 0.05). Conclusion: Maintenance anesthesia by inhalation gas base on isoflurane has not shown a significant difference with total intravenous anesthesia base on propofol on hemodynamic parameter. However, propofol has a consistent effect on decreasing stress hormone and suggested for LC surgery.
abstract_unstemmed	Background and Aims: General anesthesia induces endocrine, immunologic, and metabolic responses. Anesthetic drugs affect endocrine system by changing the level of stress hormones and hemodynamic of the patient. The purpose of this study was to compare the effects of propofol and isoflurane on hemodynamic parameters and stress-induced hormones in laparoscopic cholecystectomy (LC) surgery. Material and Methods: Seventy patients of elective LC were included in this study. Patients were randomly divided into two equal groups of 35 patients; group P received propofol (70–120 μg/kg/min) and group I received isoflurane (mac: 1.28%) as anesthesia maintenance. The following parameters were monitored, checked, and recorded from preanesthesia period to 10 min after PACU entry according to a planned method: hemodynamic parameters (heart rate and mean atrial pressure), level of blood sugar, and serum epinephrine level. Results: Heart rate and mean atrial pressure changes did not show significant differences between the two groups in all stage (P < 0.05), but isoflurane group tolerated lower fluctuating changes. Blood glucose and serum epinephrine level rise in the isoflurane group were significantly higher than the propofol group (P < 0.05). Conclusion: Maintenance anesthesia by inhalation gas base on isoflurane has not shown a significant difference with total intravenous anesthesia base on propofol on hemodynamic parameter. However, propofol has a consistent effect on decreasing stress hormone and suggested for LC surgery.
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title_short	Comparison of the effect of propofol and isoflurane on hemodynamic parameters and stress response hormones during Laparoscopic Cholecystectomy surgery
url	https://doi.org/10.4103/joacp.JOACP_146_19 https://doaj.org/article/961713570a894ef38e85bef88212b918 http://www.joacp.org/article.asp?issn=0970-9185;year=2022;volume=38;issue=1;spage=137;epage=142;aulast=Ghomeishi https://doaj.org/toc/0970-9185
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Anesthetic drugs affect endocrine system by changing the level of stress hormones and hemodynamic of the patient. The purpose of this study was to compare the effects of propofol and isoflurane on hemodynamic parameters and stress-induced hormones in laparoscopic cholecystectomy (LC) surgery. Material and Methods: Seventy patients of elective LC were included in this study. Patients were randomly divided into two equal groups of 35 patients; group P received propofol (70–120 μg/kg/min) and group I received isoflurane (mac: 1.28%) as anesthesia maintenance. The following parameters were monitored, checked, and recorded from preanesthesia period to 10 min after PACU entry according to a planned method: hemodynamic parameters (heart rate and mean atrial pressure), level of blood sugar, and serum epinephrine level. Results: Heart rate and mean atrial pressure changes did not show significant differences between the two groups in all stage (P < 0.05), but isoflurane group tolerated lower fluctuating changes. Blood glucose and serum epinephrine level rise in the isoflurane group were significantly higher than the propofol group (P < 0.05). Conclusion: Maintenance anesthesia by inhalation gas base on isoflurane has not shown a significant difference with total intravenous anesthesia base on propofol on hemodynamic parameter. However, propofol has a consistent effect on decreasing stress hormone and suggested for LC surgery.</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">hemodynamic parameters</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">isoflurane</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">laparoscopic cholecystectomy</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">propofol</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">stress hormones</subfield></datafield><datafield tag="653" ind1=" " ind2="0"><subfield code="a">Anesthesiology</subfield></datafield><datafield tag="653" ind1=" " ind2="0"><subfield code="a">Pharmacy and materia medica</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Ahmad Reza Mohtadi</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield 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Comparison of the effect of propofol and isoflurane on hemodynamic parameters and stress response hormones during Laparoscopic Cholecystectomy surgery

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