Topical therapy of molluscum contagiosum as a comparative therapeutic study using 15% phenol in lactic acid, 5% tincture iodine and pricking alone
Introduction: Molluscum contagiosum is a common viral infection of the skin, caused by poxvirus, commonly affects young children. Although there was no specific treatment for molluscum contagiosum virus, many therapeutic modalities were used with different response rates. Aims: To evaluate the effe...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Khalifa E. Sharquie [verfasserIn] Adil A. Noaimi [verfasserIn] Ghassan A. Ibrahim [verfasserIn] Ali S. Al-Husseiny [verfasserIn] |
|---|
| Format: |
E-Artikel |
|---|---|
| Sprache: |
Englisch ; Spanisch ; Französisch ; Polnisch |
| Erschienen: |
2016 |
|---|
| Schlagwörter: |
Molluscum contagiosum; Phenol in lactic acid; 5% tincture iodine |
|---|
| Übergeordnetes Werk: |
In: Nasza Dermatologia Online - Our Dermatology Online, 2011, 7(2016), 3, p 253-237 |
|---|---|
| Übergeordnetes Werk: |
volume:7 ; year:2016 ; number:3, p 253-237 |
| Links: |
|---|
| DOI / URN: |
10.7241/ourd.20163.70 |
|---|
| Katalog-ID: |
DOAJ021751455 |
|---|
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| 520 | |a Introduction: Molluscum contagiosum is a common viral infection of the skin, caused by poxvirus, commonly affects young children. Although there was no specific treatment for molluscum contagiosum virus, many therapeutic modalities were used with different response rates. Aims: To evaluate the effectiveness of topical 15% phenol in lactic acid, 5% tincture iodine and pricking alone through comparative treatments of molluscum contagiosum. Materials and Methods: This randomized, therapeutic, single, blinded, comparative study was conducted in the Department of Dermatology–Baghdad Teaching Hospital Baghdad, Iraq, during the period from October 2007 to October 2008. Seventy-five patients with molluscum contagiosum were included in this study. They were diagnosed on clinical bases. Patients with prior treatment in the last 2 weeks and patients who had inflamed lesions were excluded. Full history and physical examination were done for all Patients. The patients were divided into 3 equal groups according to the mode of therapy (25 patients for each group): Group 1 patients treated by pricking the lesions with orange stick dipped in 15% phenol in lactic acid. Group 2 patients treated by pricking the lesions with orange stick dipped in 5% tincture iodine. Group 3 patients treated by pricking with orange stick alone. The treatment sessions were done at the time of presentation and then every week until complete cure was achieved, but not more than three sessions. The patients were followed up after one month from the last session to record the clinical cure and any local or systemic side effects. Results: Seventy five patients with molluscum contagiosum, 43 (57%) males and 32 (43%) females with male to female ratio 1.3-1, their ages ranged from 2-35 years(median:6 years). The most common age groups affected were below 10 years; 57 (76%) patients. The most common affected body sites were the face and neck 58 (77.3%) patients. Atopic diseases like atopic dermatitis, allergic bronchitis were found in 17 (22.7%) patients. After 3 weeks of treatment, the response rates were as follows: Group 1: 23/25 (92%) patients cured completely, 2 (8%) patients failed to achieve complete clearing, p-value was highly significant <0.000001. Group 2: 22/25 (88%) patients completely cured, 3 (12%) patients not responded completely, p-value was highly significant < 0.000001. Group 3: 21/25 (84%) patients completely cured, 4 (16%) patients continue to develop new lesions, p-value was highly significant < 0.000001. When these groups compared with each other there was no statistically difference (p-value<0.05). Scars were not reported in any group. Conclusion: Pricking molluscum contagiosum lesions by orange stick alone is safe, cost effective, highly effective and stimulating mode of therapy. Still topical 15% phenol in lactic acid and 5% tincture iodine are new and effective modes of treatment. | ||
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10.7241/ourd.20163.70 doi (DE-627)DOAJ021751455 (DE-599)DOAJeeaf3af1d8fa40a889efd629c2efb427 DE-627 ger DE-627 rakwb eng spa fre pol RL1-803 Khalifa E. Sharquie verfasserin aut Topical therapy of molluscum contagiosum as a comparative therapeutic study using 15% phenol in lactic acid, 5% tincture iodine and pricking alone 2016 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Introduction: Molluscum contagiosum is a common viral infection of the skin, caused by poxvirus, commonly affects young children. Although there was no specific treatment for molluscum contagiosum virus, many therapeutic modalities were used with different response rates. Aims: To evaluate the effectiveness of topical 15% phenol in lactic acid, 5% tincture iodine and pricking alone through comparative treatments of molluscum contagiosum. Materials and Methods: This randomized, therapeutic, single, blinded, comparative study was conducted in the Department of Dermatology–Baghdad Teaching Hospital Baghdad, Iraq, during the period from October 2007 to October 2008. Seventy-five patients with molluscum contagiosum were included in this study. They were diagnosed on clinical bases. Patients with prior treatment in the last 2 weeks and patients who had inflamed lesions were excluded. Full history and physical examination were done for all Patients. The patients were divided into 3 equal groups according to the mode of therapy (25 patients for each group): Group 1 patients treated by pricking the lesions with orange stick dipped in 15% phenol in lactic acid. Group 2 patients treated by pricking the lesions with orange stick dipped in 5% tincture iodine. Group 3 patients treated by pricking with orange stick alone. The treatment sessions were done at the time of presentation and then every week until complete cure was achieved, but not more than three sessions. The patients were followed up after one month from the last session to record the clinical cure and any local or systemic side effects. Results: Seventy five patients with molluscum contagiosum, 43 (57%) males and 32 (43%) females with male to female ratio 1.3-1, their ages ranged from 2-35 years(median:6 years). The most common age groups affected were below 10 years; 57 (76%) patients. The most common affected body sites were the face and neck 58 (77.3%) patients. Atopic diseases like atopic dermatitis, allergic bronchitis were found in 17 (22.7%) patients. After 3 weeks of treatment, the response rates were as follows: Group 1: 23/25 (92%) patients cured completely, 2 (8%) patients failed to achieve complete clearing, p-value was highly significant <0.000001. Group 2: 22/25 (88%) patients completely cured, 3 (12%) patients not responded completely, p-value was highly significant < 0.000001. Group 3: 21/25 (84%) patients completely cured, 4 (16%) patients continue to develop new lesions, p-value was highly significant < 0.000001. When these groups compared with each other there was no statistically difference (p-value<0.05). Scars were not reported in any group. Conclusion: Pricking molluscum contagiosum lesions by orange stick alone is safe, cost effective, highly effective and stimulating mode of therapy. Still topical 15% phenol in lactic acid and 5% tincture iodine are new and effective modes of treatment. Molluscum contagiosum; Phenol in lactic acid; 5% tincture iodine Dermatology Adil A. Noaimi verfasserin aut Ghassan A. Ibrahim verfasserin aut Ali S. Al-Husseiny verfasserin aut In Nasza Dermatologia Online Our Dermatology Online, 2011 7(2016), 3, p 253-237 (DE-627)1760606286 20819390 nnns volume:7 year:2016 number:3, p 253-237 https://doi.org/10.7241/ourd.20163.70 kostenfrei https://doaj.org/article/eeaf3af1d8fa40a889efd629c2efb427 kostenfrei http://www.odermatol.com/issue-in-html/2016-3-1/ kostenfrei https://doaj.org/toc/2081-9390 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_206 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4305 AR 7 2016 3, p 253-237 |
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10.7241/ourd.20163.70 doi (DE-627)DOAJ021751455 (DE-599)DOAJeeaf3af1d8fa40a889efd629c2efb427 DE-627 ger DE-627 rakwb eng spa fre pol RL1-803 Khalifa E. Sharquie verfasserin aut Topical therapy of molluscum contagiosum as a comparative therapeutic study using 15% phenol in lactic acid, 5% tincture iodine and pricking alone 2016 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Introduction: Molluscum contagiosum is a common viral infection of the skin, caused by poxvirus, commonly affects young children. Although there was no specific treatment for molluscum contagiosum virus, many therapeutic modalities were used with different response rates. Aims: To evaluate the effectiveness of topical 15% phenol in lactic acid, 5% tincture iodine and pricking alone through comparative treatments of molluscum contagiosum. Materials and Methods: This randomized, therapeutic, single, blinded, comparative study was conducted in the Department of Dermatology–Baghdad Teaching Hospital Baghdad, Iraq, during the period from October 2007 to October 2008. Seventy-five patients with molluscum contagiosum were included in this study. They were diagnosed on clinical bases. Patients with prior treatment in the last 2 weeks and patients who had inflamed lesions were excluded. Full history and physical examination were done for all Patients. The patients were divided into 3 equal groups according to the mode of therapy (25 patients for each group): Group 1 patients treated by pricking the lesions with orange stick dipped in 15% phenol in lactic acid. Group 2 patients treated by pricking the lesions with orange stick dipped in 5% tincture iodine. Group 3 patients treated by pricking with orange stick alone. The treatment sessions were done at the time of presentation and then every week until complete cure was achieved, but not more than three sessions. The patients were followed up after one month from the last session to record the clinical cure and any local or systemic side effects. Results: Seventy five patients with molluscum contagiosum, 43 (57%) males and 32 (43%) females with male to female ratio 1.3-1, their ages ranged from 2-35 years(median:6 years). The most common age groups affected were below 10 years; 57 (76%) patients. The most common affected body sites were the face and neck 58 (77.3%) patients. Atopic diseases like atopic dermatitis, allergic bronchitis were found in 17 (22.7%) patients. After 3 weeks of treatment, the response rates were as follows: Group 1: 23/25 (92%) patients cured completely, 2 (8%) patients failed to achieve complete clearing, p-value was highly significant <0.000001. Group 2: 22/25 (88%) patients completely cured, 3 (12%) patients not responded completely, p-value was highly significant < 0.000001. Group 3: 21/25 (84%) patients completely cured, 4 (16%) patients continue to develop new lesions, p-value was highly significant < 0.000001. When these groups compared with each other there was no statistically difference (p-value<0.05). Scars were not reported in any group. Conclusion: Pricking molluscum contagiosum lesions by orange stick alone is safe, cost effective, highly effective and stimulating mode of therapy. Still topical 15% phenol in lactic acid and 5% tincture iodine are new and effective modes of treatment. Molluscum contagiosum; Phenol in lactic acid; 5% tincture iodine Dermatology Adil A. Noaimi verfasserin aut Ghassan A. Ibrahim verfasserin aut Ali S. Al-Husseiny verfasserin aut In Nasza Dermatologia Online Our Dermatology Online, 2011 7(2016), 3, p 253-237 (DE-627)1760606286 20819390 nnns volume:7 year:2016 number:3, p 253-237 https://doi.org/10.7241/ourd.20163.70 kostenfrei https://doaj.org/article/eeaf3af1d8fa40a889efd629c2efb427 kostenfrei http://www.odermatol.com/issue-in-html/2016-3-1/ kostenfrei https://doaj.org/toc/2081-9390 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_206 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4305 AR 7 2016 3, p 253-237 |
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10.7241/ourd.20163.70 doi (DE-627)DOAJ021751455 (DE-599)DOAJeeaf3af1d8fa40a889efd629c2efb427 DE-627 ger DE-627 rakwb eng spa fre pol RL1-803 Khalifa E. Sharquie verfasserin aut Topical therapy of molluscum contagiosum as a comparative therapeutic study using 15% phenol in lactic acid, 5% tincture iodine and pricking alone 2016 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Introduction: Molluscum contagiosum is a common viral infection of the skin, caused by poxvirus, commonly affects young children. Although there was no specific treatment for molluscum contagiosum virus, many therapeutic modalities were used with different response rates. Aims: To evaluate the effectiveness of topical 15% phenol in lactic acid, 5% tincture iodine and pricking alone through comparative treatments of molluscum contagiosum. Materials and Methods: This randomized, therapeutic, single, blinded, comparative study was conducted in the Department of Dermatology–Baghdad Teaching Hospital Baghdad, Iraq, during the period from October 2007 to October 2008. Seventy-five patients with molluscum contagiosum were included in this study. They were diagnosed on clinical bases. Patients with prior treatment in the last 2 weeks and patients who had inflamed lesions were excluded. Full history and physical examination were done for all Patients. The patients were divided into 3 equal groups according to the mode of therapy (25 patients for each group): Group 1 patients treated by pricking the lesions with orange stick dipped in 15% phenol in lactic acid. Group 2 patients treated by pricking the lesions with orange stick dipped in 5% tincture iodine. Group 3 patients treated by pricking with orange stick alone. The treatment sessions were done at the time of presentation and then every week until complete cure was achieved, but not more than three sessions. The patients were followed up after one month from the last session to record the clinical cure and any local or systemic side effects. Results: Seventy five patients with molluscum contagiosum, 43 (57%) males and 32 (43%) females with male to female ratio 1.3-1, their ages ranged from 2-35 years(median:6 years). The most common age groups affected were below 10 years; 57 (76%) patients. The most common affected body sites were the face and neck 58 (77.3%) patients. Atopic diseases like atopic dermatitis, allergic bronchitis were found in 17 (22.7%) patients. After 3 weeks of treatment, the response rates were as follows: Group 1: 23/25 (92%) patients cured completely, 2 (8%) patients failed to achieve complete clearing, p-value was highly significant <0.000001. Group 2: 22/25 (88%) patients completely cured, 3 (12%) patients not responded completely, p-value was highly significant < 0.000001. Group 3: 21/25 (84%) patients completely cured, 4 (16%) patients continue to develop new lesions, p-value was highly significant < 0.000001. When these groups compared with each other there was no statistically difference (p-value<0.05). Scars were not reported in any group. Conclusion: Pricking molluscum contagiosum lesions by orange stick alone is safe, cost effective, highly effective and stimulating mode of therapy. Still topical 15% phenol in lactic acid and 5% tincture iodine are new and effective modes of treatment. Molluscum contagiosum; Phenol in lactic acid; 5% tincture iodine Dermatology Adil A. Noaimi verfasserin aut Ghassan A. Ibrahim verfasserin aut Ali S. Al-Husseiny verfasserin aut In Nasza Dermatologia Online Our Dermatology Online, 2011 7(2016), 3, p 253-237 (DE-627)1760606286 20819390 nnns volume:7 year:2016 number:3, p 253-237 https://doi.org/10.7241/ourd.20163.70 kostenfrei https://doaj.org/article/eeaf3af1d8fa40a889efd629c2efb427 kostenfrei http://www.odermatol.com/issue-in-html/2016-3-1/ kostenfrei https://doaj.org/toc/2081-9390 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_206 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4305 AR 7 2016 3, p 253-237 |
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10.7241/ourd.20163.70 doi (DE-627)DOAJ021751455 (DE-599)DOAJeeaf3af1d8fa40a889efd629c2efb427 DE-627 ger DE-627 rakwb eng spa fre pol RL1-803 Khalifa E. Sharquie verfasserin aut Topical therapy of molluscum contagiosum as a comparative therapeutic study using 15% phenol in lactic acid, 5% tincture iodine and pricking alone 2016 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Introduction: Molluscum contagiosum is a common viral infection of the skin, caused by poxvirus, commonly affects young children. Although there was no specific treatment for molluscum contagiosum virus, many therapeutic modalities were used with different response rates. Aims: To evaluate the effectiveness of topical 15% phenol in lactic acid, 5% tincture iodine and pricking alone through comparative treatments of molluscum contagiosum. Materials and Methods: This randomized, therapeutic, single, blinded, comparative study was conducted in the Department of Dermatology–Baghdad Teaching Hospital Baghdad, Iraq, during the period from October 2007 to October 2008. Seventy-five patients with molluscum contagiosum were included in this study. They were diagnosed on clinical bases. Patients with prior treatment in the last 2 weeks and patients who had inflamed lesions were excluded. Full history and physical examination were done for all Patients. The patients were divided into 3 equal groups according to the mode of therapy (25 patients for each group): Group 1 patients treated by pricking the lesions with orange stick dipped in 15% phenol in lactic acid. Group 2 patients treated by pricking the lesions with orange stick dipped in 5% tincture iodine. Group 3 patients treated by pricking with orange stick alone. The treatment sessions were done at the time of presentation and then every week until complete cure was achieved, but not more than three sessions. The patients were followed up after one month from the last session to record the clinical cure and any local or systemic side effects. Results: Seventy five patients with molluscum contagiosum, 43 (57%) males and 32 (43%) females with male to female ratio 1.3-1, their ages ranged from 2-35 years(median:6 years). The most common age groups affected were below 10 years; 57 (76%) patients. The most common affected body sites were the face and neck 58 (77.3%) patients. Atopic diseases like atopic dermatitis, allergic bronchitis were found in 17 (22.7%) patients. After 3 weeks of treatment, the response rates were as follows: Group 1: 23/25 (92%) patients cured completely, 2 (8%) patients failed to achieve complete clearing, p-value was highly significant <0.000001. Group 2: 22/25 (88%) patients completely cured, 3 (12%) patients not responded completely, p-value was highly significant < 0.000001. Group 3: 21/25 (84%) patients completely cured, 4 (16%) patients continue to develop new lesions, p-value was highly significant < 0.000001. When these groups compared with each other there was no statistically difference (p-value<0.05). Scars were not reported in any group. Conclusion: Pricking molluscum contagiosum lesions by orange stick alone is safe, cost effective, highly effective and stimulating mode of therapy. Still topical 15% phenol in lactic acid and 5% tincture iodine are new and effective modes of treatment. Molluscum contagiosum; Phenol in lactic acid; 5% tincture iodine Dermatology Adil A. Noaimi verfasserin aut Ghassan A. Ibrahim verfasserin aut Ali S. Al-Husseiny verfasserin aut In Nasza Dermatologia Online Our Dermatology Online, 2011 7(2016), 3, p 253-237 (DE-627)1760606286 20819390 nnns volume:7 year:2016 number:3, p 253-237 https://doi.org/10.7241/ourd.20163.70 kostenfrei https://doaj.org/article/eeaf3af1d8fa40a889efd629c2efb427 kostenfrei http://www.odermatol.com/issue-in-html/2016-3-1/ kostenfrei https://doaj.org/toc/2081-9390 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_206 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4305 AR 7 2016 3, p 253-237 |
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10.7241/ourd.20163.70 doi (DE-627)DOAJ021751455 (DE-599)DOAJeeaf3af1d8fa40a889efd629c2efb427 DE-627 ger DE-627 rakwb eng spa fre pol RL1-803 Khalifa E. Sharquie verfasserin aut Topical therapy of molluscum contagiosum as a comparative therapeutic study using 15% phenol in lactic acid, 5% tincture iodine and pricking alone 2016 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Introduction: Molluscum contagiosum is a common viral infection of the skin, caused by poxvirus, commonly affects young children. Although there was no specific treatment for molluscum contagiosum virus, many therapeutic modalities were used with different response rates. Aims: To evaluate the effectiveness of topical 15% phenol in lactic acid, 5% tincture iodine and pricking alone through comparative treatments of molluscum contagiosum. Materials and Methods: This randomized, therapeutic, single, blinded, comparative study was conducted in the Department of Dermatology–Baghdad Teaching Hospital Baghdad, Iraq, during the period from October 2007 to October 2008. Seventy-five patients with molluscum contagiosum were included in this study. They were diagnosed on clinical bases. Patients with prior treatment in the last 2 weeks and patients who had inflamed lesions were excluded. Full history and physical examination were done for all Patients. The patients were divided into 3 equal groups according to the mode of therapy (25 patients for each group): Group 1 patients treated by pricking the lesions with orange stick dipped in 15% phenol in lactic acid. Group 2 patients treated by pricking the lesions with orange stick dipped in 5% tincture iodine. Group 3 patients treated by pricking with orange stick alone. The treatment sessions were done at the time of presentation and then every week until complete cure was achieved, but not more than three sessions. The patients were followed up after one month from the last session to record the clinical cure and any local or systemic side effects. Results: Seventy five patients with molluscum contagiosum, 43 (57%) males and 32 (43%) females with male to female ratio 1.3-1, their ages ranged from 2-35 years(median:6 years). The most common age groups affected were below 10 years; 57 (76%) patients. The most common affected body sites were the face and neck 58 (77.3%) patients. Atopic diseases like atopic dermatitis, allergic bronchitis were found in 17 (22.7%) patients. After 3 weeks of treatment, the response rates were as follows: Group 1: 23/25 (92%) patients cured completely, 2 (8%) patients failed to achieve complete clearing, p-value was highly significant <0.000001. Group 2: 22/25 (88%) patients completely cured, 3 (12%) patients not responded completely, p-value was highly significant < 0.000001. Group 3: 21/25 (84%) patients completely cured, 4 (16%) patients continue to develop new lesions, p-value was highly significant < 0.000001. When these groups compared with each other there was no statistically difference (p-value<0.05). Scars were not reported in any group. Conclusion: Pricking molluscum contagiosum lesions by orange stick alone is safe, cost effective, highly effective and stimulating mode of therapy. Still topical 15% phenol in lactic acid and 5% tincture iodine are new and effective modes of treatment. Molluscum contagiosum; Phenol in lactic acid; 5% tincture iodine Dermatology Adil A. Noaimi verfasserin aut Ghassan A. Ibrahim verfasserin aut Ali S. Al-Husseiny verfasserin aut In Nasza Dermatologia Online Our Dermatology Online, 2011 7(2016), 3, p 253-237 (DE-627)1760606286 20819390 nnns volume:7 year:2016 number:3, p 253-237 https://doi.org/10.7241/ourd.20163.70 kostenfrei https://doaj.org/article/eeaf3af1d8fa40a889efd629c2efb427 kostenfrei http://www.odermatol.com/issue-in-html/2016-3-1/ kostenfrei https://doaj.org/toc/2081-9390 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_206 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4305 AR 7 2016 3, p 253-237 |
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Sharquie</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Topical therapy of molluscum contagiosum as a comparative therapeutic study using 15% phenol in lactic acid, 5% tincture iodine and pricking alone</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="c">2016</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">Text</subfield><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">Computermedien</subfield><subfield code="b">c</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">Online-Ressource</subfield><subfield code="b">cr</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">Introduction: Molluscum contagiosum is a common viral infection of the skin, caused by poxvirus, commonly affects young children. Although there was no specific treatment for molluscum contagiosum virus, many therapeutic modalities were used with different response rates. Aims: To evaluate the effectiveness of topical 15% phenol in lactic acid, 5% tincture iodine and pricking alone through comparative treatments of molluscum contagiosum. Materials and Methods: This randomized, therapeutic, single, blinded, comparative study was conducted in the Department of Dermatology–Baghdad Teaching Hospital Baghdad, Iraq, during the period from October 2007 to October 2008. Seventy-five patients with molluscum contagiosum were included in this study. They were diagnosed on clinical bases. Patients with prior treatment in the last 2 weeks and patients who had inflamed lesions were excluded. Full history and physical examination were done for all Patients. The patients were divided into 3 equal groups according to the mode of therapy (25 patients for each group): Group 1 patients treated by pricking the lesions with orange stick dipped in 15% phenol in lactic acid. Group 2 patients treated by pricking the lesions with orange stick dipped in 5% tincture iodine. Group 3 patients treated by pricking with orange stick alone. The treatment sessions were done at the time of presentation and then every week until complete cure was achieved, but not more than three sessions. The patients were followed up after one month from the last session to record the clinical cure and any local or systemic side effects. Results: Seventy five patients with molluscum contagiosum, 43 (57%) males and 32 (43%) females with male to female ratio 1.3-1, their ages ranged from 2-35 years(median:6 years). The most common age groups affected were below 10 years; 57 (76%) patients. The most common affected body sites were the face and neck 58 (77.3%) patients. Atopic diseases like atopic dermatitis, allergic bronchitis were found in 17 (22.7%) patients. After 3 weeks of treatment, the response rates were as follows: Group 1: 23/25 (92%) patients cured completely, 2 (8%) patients failed to achieve complete clearing, p-value was highly significant <0.000001. Group 2: 22/25 (88%) patients completely cured, 3 (12%) patients not responded completely, p-value was highly significant < 0.000001. Group 3: 21/25 (84%) patients completely cured, 4 (16%) patients continue to develop new lesions, p-value was highly significant < 0.000001. When these groups compared with each other there was no statistically difference (p-value<0.05). Scars were not reported in any group. Conclusion: Pricking molluscum contagiosum lesions by orange stick alone is safe, cost effective, highly effective and stimulating mode of therapy. 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Khalifa E. Sharquie |
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RL1-803 Topical therapy of molluscum contagiosum as a comparative therapeutic study using 15% phenol in lactic acid, 5% tincture iodine and pricking alone Molluscum contagiosum; Phenol in lactic acid; 5% tincture iodine |
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Topical therapy of molluscum contagiosum as a comparative therapeutic study using 15% phenol in lactic acid, 5% tincture iodine and pricking alone |
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topical therapy of molluscum contagiosum as a comparative therapeutic study using 15% phenol in lactic acid, 5% tincture iodine and pricking alone |
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Topical therapy of molluscum contagiosum as a comparative therapeutic study using 15% phenol in lactic acid, 5% tincture iodine and pricking alone |
| abstract |
Introduction: Molluscum contagiosum is a common viral infection of the skin, caused by poxvirus, commonly affects young children. Although there was no specific treatment for molluscum contagiosum virus, many therapeutic modalities were used with different response rates. Aims: To evaluate the effectiveness of topical 15% phenol in lactic acid, 5% tincture iodine and pricking alone through comparative treatments of molluscum contagiosum. Materials and Methods: This randomized, therapeutic, single, blinded, comparative study was conducted in the Department of Dermatology–Baghdad Teaching Hospital Baghdad, Iraq, during the period from October 2007 to October 2008. Seventy-five patients with molluscum contagiosum were included in this study. They were diagnosed on clinical bases. Patients with prior treatment in the last 2 weeks and patients who had inflamed lesions were excluded. Full history and physical examination were done for all Patients. The patients were divided into 3 equal groups according to the mode of therapy (25 patients for each group): Group 1 patients treated by pricking the lesions with orange stick dipped in 15% phenol in lactic acid. Group 2 patients treated by pricking the lesions with orange stick dipped in 5% tincture iodine. Group 3 patients treated by pricking with orange stick alone. The treatment sessions were done at the time of presentation and then every week until complete cure was achieved, but not more than three sessions. The patients were followed up after one month from the last session to record the clinical cure and any local or systemic side effects. Results: Seventy five patients with molluscum contagiosum, 43 (57%) males and 32 (43%) females with male to female ratio 1.3-1, their ages ranged from 2-35 years(median:6 years). The most common age groups affected were below 10 years; 57 (76%) patients. The most common affected body sites were the face and neck 58 (77.3%) patients. Atopic diseases like atopic dermatitis, allergic bronchitis were found in 17 (22.7%) patients. After 3 weeks of treatment, the response rates were as follows: Group 1: 23/25 (92%) patients cured completely, 2 (8%) patients failed to achieve complete clearing, p-value was highly significant <0.000001. Group 2: 22/25 (88%) patients completely cured, 3 (12%) patients not responded completely, p-value was highly significant < 0.000001. Group 3: 21/25 (84%) patients completely cured, 4 (16%) patients continue to develop new lesions, p-value was highly significant < 0.000001. When these groups compared with each other there was no statistically difference (p-value<0.05). Scars were not reported in any group. Conclusion: Pricking molluscum contagiosum lesions by orange stick alone is safe, cost effective, highly effective and stimulating mode of therapy. Still topical 15% phenol in lactic acid and 5% tincture iodine are new and effective modes of treatment. |
| abstractGer |
Introduction: Molluscum contagiosum is a common viral infection of the skin, caused by poxvirus, commonly affects young children. Although there was no specific treatment for molluscum contagiosum virus, many therapeutic modalities were used with different response rates. Aims: To evaluate the effectiveness of topical 15% phenol in lactic acid, 5% tincture iodine and pricking alone through comparative treatments of molluscum contagiosum. Materials and Methods: This randomized, therapeutic, single, blinded, comparative study was conducted in the Department of Dermatology–Baghdad Teaching Hospital Baghdad, Iraq, during the period from October 2007 to October 2008. Seventy-five patients with molluscum contagiosum were included in this study. They were diagnosed on clinical bases. Patients with prior treatment in the last 2 weeks and patients who had inflamed lesions were excluded. Full history and physical examination were done for all Patients. The patients were divided into 3 equal groups according to the mode of therapy (25 patients for each group): Group 1 patients treated by pricking the lesions with orange stick dipped in 15% phenol in lactic acid. Group 2 patients treated by pricking the lesions with orange stick dipped in 5% tincture iodine. Group 3 patients treated by pricking with orange stick alone. The treatment sessions were done at the time of presentation and then every week until complete cure was achieved, but not more than three sessions. The patients were followed up after one month from the last session to record the clinical cure and any local or systemic side effects. Results: Seventy five patients with molluscum contagiosum, 43 (57%) males and 32 (43%) females with male to female ratio 1.3-1, their ages ranged from 2-35 years(median:6 years). The most common age groups affected were below 10 years; 57 (76%) patients. The most common affected body sites were the face and neck 58 (77.3%) patients. Atopic diseases like atopic dermatitis, allergic bronchitis were found in 17 (22.7%) patients. After 3 weeks of treatment, the response rates were as follows: Group 1: 23/25 (92%) patients cured completely, 2 (8%) patients failed to achieve complete clearing, p-value was highly significant <0.000001. Group 2: 22/25 (88%) patients completely cured, 3 (12%) patients not responded completely, p-value was highly significant < 0.000001. Group 3: 21/25 (84%) patients completely cured, 4 (16%) patients continue to develop new lesions, p-value was highly significant < 0.000001. When these groups compared with each other there was no statistically difference (p-value<0.05). Scars were not reported in any group. Conclusion: Pricking molluscum contagiosum lesions by orange stick alone is safe, cost effective, highly effective and stimulating mode of therapy. Still topical 15% phenol in lactic acid and 5% tincture iodine are new and effective modes of treatment. |
| abstract_unstemmed |
Introduction: Molluscum contagiosum is a common viral infection of the skin, caused by poxvirus, commonly affects young children. Although there was no specific treatment for molluscum contagiosum virus, many therapeutic modalities were used with different response rates. Aims: To evaluate the effectiveness of topical 15% phenol in lactic acid, 5% tincture iodine and pricking alone through comparative treatments of molluscum contagiosum. Materials and Methods: This randomized, therapeutic, single, blinded, comparative study was conducted in the Department of Dermatology–Baghdad Teaching Hospital Baghdad, Iraq, during the period from October 2007 to October 2008. Seventy-five patients with molluscum contagiosum were included in this study. They were diagnosed on clinical bases. Patients with prior treatment in the last 2 weeks and patients who had inflamed lesions were excluded. Full history and physical examination were done for all Patients. The patients were divided into 3 equal groups according to the mode of therapy (25 patients for each group): Group 1 patients treated by pricking the lesions with orange stick dipped in 15% phenol in lactic acid. Group 2 patients treated by pricking the lesions with orange stick dipped in 5% tincture iodine. Group 3 patients treated by pricking with orange stick alone. The treatment sessions were done at the time of presentation and then every week until complete cure was achieved, but not more than three sessions. The patients were followed up after one month from the last session to record the clinical cure and any local or systemic side effects. Results: Seventy five patients with molluscum contagiosum, 43 (57%) males and 32 (43%) females with male to female ratio 1.3-1, their ages ranged from 2-35 years(median:6 years). The most common age groups affected were below 10 years; 57 (76%) patients. The most common affected body sites were the face and neck 58 (77.3%) patients. Atopic diseases like atopic dermatitis, allergic bronchitis were found in 17 (22.7%) patients. After 3 weeks of treatment, the response rates were as follows: Group 1: 23/25 (92%) patients cured completely, 2 (8%) patients failed to achieve complete clearing, p-value was highly significant <0.000001. Group 2: 22/25 (88%) patients completely cured, 3 (12%) patients not responded completely, p-value was highly significant < 0.000001. Group 3: 21/25 (84%) patients completely cured, 4 (16%) patients continue to develop new lesions, p-value was highly significant < 0.000001. When these groups compared with each other there was no statistically difference (p-value<0.05). Scars were not reported in any group. Conclusion: Pricking molluscum contagiosum lesions by orange stick alone is safe, cost effective, highly effective and stimulating mode of therapy. Still topical 15% phenol in lactic acid and 5% tincture iodine are new and effective modes of treatment. |
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Atopic diseases like atopic dermatitis, allergic bronchitis were found in 17 (22.7%) patients. After 3 weeks of treatment, the response rates were as follows: Group 1: 23/25 (92%) patients cured completely, 2 (8%) patients failed to achieve complete clearing, p-value was highly significant <0.000001. Group 2: 22/25 (88%) patients completely cured, 3 (12%) patients not responded completely, p-value was highly significant < 0.000001. Group 3: 21/25 (84%) patients completely cured, 4 (16%) patients continue to develop new lesions, p-value was highly significant < 0.000001. When these groups compared with each other there was no statistically difference (p-value<0.05). Scars were not reported in any group. Conclusion: Pricking molluscum contagiosum lesions by orange stick alone is safe, cost effective, highly effective and stimulating mode of therapy. 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