Efficiency and safety of video-assisted mediastinal lymphadenectomy in the treatment of non-small cell lung cancer

INTRODUCTION. A number of studies demonstrate the advantage of bilateral mediastinal lymphadenectomy in surgery of non-small cell lung cancer (nSCLC). For surgical approach to the opposite mediastinum for many years there were proposed sternotomy, video-thoracoscopy, and transcervical video-assisted interventions. In our practice, we use videoassisted mediastinal lymphadenectomy (VAMLA).The OBJECTIVE was to learn the efficiency and safety of VAMLA in surgery of NSCLC.METHODS AND MATERIALS. The study included the materials of examination and treatment of 102 patients with NSCLC. 102 patients were divided into 2 groups. In the 1st group (54 patients), VAMLA and lung resection were performed. In the 2nd group (48 patients): anatomical lung resection and systematic ipsilateral lymphadenectomy (SLD) were performed.RESULTS. The average number of remote lymph node stations in group 1 was (7.8±1.7); in group 2 – (4.5±1.2) (p<0.05). The average number of lymph nodes was 26±8.6 compared to (14.3±6) in both groups, respectively (p<0.05). «Occult» pN2-N3 metastasis was detected in 20 % (7/34) of patients of the group 1 and 6.5 % (2/31) of patients of the group 2 (p<0.05). The level of postoperative complications in both groups was 33.4 vs. 29.2 %, respectively (p>0.05). The duration of the postoperative day ((12.7±4.9) vs. (13.7±6.5)) and the duration of pleural drainage ((5.5±4.2) vs. (5.8±4.4)) did not differ in both groups (p>0.05).CONCLUSION. VAMLA is an effective and safe method for evaluating the pN stage of NSCLC. Performing VAMLA in left-sided NSCLC allows removing significantly more lymph nodes and stations in comparison with SLD available in VATS and thoracotomy, which increases the accuracy of postoperative N-staging. The use of the VAMLA in minimally invasive surgery of right-sided NSCLC may be promising in cases of high risk of «occult» pN3 lesion, but requires further study of the role of contralateral lymphatic dissection. Ausführliche Beschreibung

Gespeichert in:

Autor*in:	A. A. Skorokhod [verfasserIn] A. S. Petrov [verfasserIn] A. R. Kozak [verfasserIn] M. A. Atyukov [verfasserIn] A. O. Nefedov [verfasserIn] P. K. Yаblonskiy [verfasserIn]

Format:	E-Artikel
Sprache:	Russisch

Erschienen:	2021

Schlagwörter:	video-assisted mediastinal lymphadenectomy vamla bilateral lymphatic dissection non-small cell lung cancer lung resection surgical treatment

Übergeordnetes Werk:	In: Вестник хирургии имени И.И. Грекова - Pavlov First Saint Petersburg State Medical University, 2019, 179(2021), 6, Seite 24-33
Übergeordnetes Werk:	volume:179 ; year:2021 ; number:6 ; pages:24-33

Links:	Link aufrufen Link aufrufen Link aufrufen Journal toc

DOI / URN:	10.24884/0042-4625-2020-179-6-24-33

Katalog-ID:	DOAJ021811334

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allfields	10.24884/0042-4625-2020-179-6-24-33 doi (DE-627)DOAJ021811334 (DE-599)DOAJ13bea76a88434d24a50bbfc079ccbf61 DE-627 ger DE-627 rakwb rus RD1-811 A. A. Skorokhod verfasserin aut Efficiency and safety of video-assisted mediastinal lymphadenectomy in the treatment of non-small cell lung cancer 2021 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier INTRODUCTION. A number of studies demonstrate the advantage of bilateral mediastinal lymphadenectomy in surgery of non-small cell lung cancer (nSCLC). For surgical approach to the opposite mediastinum for many years there were proposed sternotomy, video-thoracoscopy, and transcervical video-assisted interventions. In our practice, we use videoassisted mediastinal lymphadenectomy (VAMLA).The OBJECTIVE was to learn the efficiency and safety of VAMLA in surgery of NSCLC.METHODS AND MATERIALS. The study included the materials of examination and treatment of 102 patients with NSCLC. 102 patients were divided into 2 groups. In the 1st group (54 patients), VAMLA and lung resection were performed. In the 2nd group (48 patients): anatomical lung resection and systematic ipsilateral lymphadenectomy (SLD) were performed.RESULTS. The average number of remote lymph node stations in group 1 was (7.8±1.7); in group 2 – (4.5±1.2) (p<0.05). The average number of lymph nodes was 26±8.6 compared to (14.3±6) in both groups, respectively (p<0.05). «Occult» pN2-N3 metastasis was detected in 20 % (7/34) of patients of the group 1 and 6.5 % (2/31) of patients of the group 2 (p<0.05). The level of postoperative complications in both groups was 33.4 vs. 29.2 %, respectively (p>0.05). The duration of the postoperative day ((12.7±4.9) vs. (13.7±6.5)) and the duration of pleural drainage ((5.5±4.2) vs. (5.8±4.4)) did not differ in both groups (p>0.05).CONCLUSION. VAMLA is an effective and safe method for evaluating the pN stage of NSCLC. Performing VAMLA in left-sided NSCLC allows removing significantly more lymph nodes and stations in comparison with SLD available in VATS and thoracotomy, which increases the accuracy of postoperative N-staging. The use of the VAMLA in minimally invasive surgery of right-sided NSCLC may be promising in cases of high risk of «occult» pN3 lesion, but requires further study of the role of contralateral lymphatic dissection. video-assisted mediastinal lymphadenectomy vamla bilateral lymphatic dissection non-small cell lung cancer lung resection surgical treatment Surgery A. S. Petrov verfasserin aut A. R. Kozak verfasserin aut M. A. Atyukov verfasserin aut A. O. Nefedov verfasserin aut P. K. Yаblonskiy verfasserin aut In Вестник хирургии имени И.И. Грекова Pavlov First Saint Petersburg State Medical University, 2019 179(2021), 6, Seite 24-33 (DE-627)1697861369 00424625 nnns volume:179 year:2021 number:6 pages:24-33 https://doi.org/10.24884/0042-4625-2020-179-6-24-33 kostenfrei https://doaj.org/article/13bea76a88434d24a50bbfc079ccbf61 kostenfrei https://www.vestnik-grekova.ru/jour/article/view/1632 kostenfrei https://doaj.org/toc/0042-4625 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 179 2021 6 24-33
spelling	10.24884/0042-4625-2020-179-6-24-33 doi (DE-627)DOAJ021811334 (DE-599)DOAJ13bea76a88434d24a50bbfc079ccbf61 DE-627 ger DE-627 rakwb rus RD1-811 A. A. Skorokhod verfasserin aut Efficiency and safety of video-assisted mediastinal lymphadenectomy in the treatment of non-small cell lung cancer 2021 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier INTRODUCTION. A number of studies demonstrate the advantage of bilateral mediastinal lymphadenectomy in surgery of non-small cell lung cancer (nSCLC). For surgical approach to the opposite mediastinum for many years there were proposed sternotomy, video-thoracoscopy, and transcervical video-assisted interventions. In our practice, we use videoassisted mediastinal lymphadenectomy (VAMLA).The OBJECTIVE was to learn the efficiency and safety of VAMLA in surgery of NSCLC.METHODS AND MATERIALS. The study included the materials of examination and treatment of 102 patients with NSCLC. 102 patients were divided into 2 groups. In the 1st group (54 patients), VAMLA and lung resection were performed. In the 2nd group (48 patients): anatomical lung resection and systematic ipsilateral lymphadenectomy (SLD) were performed.RESULTS. The average number of remote lymph node stations in group 1 was (7.8±1.7); in group 2 – (4.5±1.2) (p<0.05). The average number of lymph nodes was 26±8.6 compared to (14.3±6) in both groups, respectively (p<0.05). «Occult» pN2-N3 metastasis was detected in 20 % (7/34) of patients of the group 1 and 6.5 % (2/31) of patients of the group 2 (p<0.05). The level of postoperative complications in both groups was 33.4 vs. 29.2 %, respectively (p>0.05). The duration of the postoperative day ((12.7±4.9) vs. (13.7±6.5)) and the duration of pleural drainage ((5.5±4.2) vs. (5.8±4.4)) did not differ in both groups (p>0.05).CONCLUSION. VAMLA is an effective and safe method for evaluating the pN stage of NSCLC. Performing VAMLA in left-sided NSCLC allows removing significantly more lymph nodes and stations in comparison with SLD available in VATS and thoracotomy, which increases the accuracy of postoperative N-staging. The use of the VAMLA in minimally invasive surgery of right-sided NSCLC may be promising in cases of high risk of «occult» pN3 lesion, but requires further study of the role of contralateral lymphatic dissection. video-assisted mediastinal lymphadenectomy vamla bilateral lymphatic dissection non-small cell lung cancer lung resection surgical treatment Surgery A. S. Petrov verfasserin aut A. R. Kozak verfasserin aut M. A. Atyukov verfasserin aut A. O. Nefedov verfasserin aut P. K. Yаblonskiy verfasserin aut In Вестник хирургии имени И.И. Грекова Pavlov First Saint Petersburg State Medical University, 2019 179(2021), 6, Seite 24-33 (DE-627)1697861369 00424625 nnns volume:179 year:2021 number:6 pages:24-33 https://doi.org/10.24884/0042-4625-2020-179-6-24-33 kostenfrei https://doaj.org/article/13bea76a88434d24a50bbfc079ccbf61 kostenfrei https://www.vestnik-grekova.ru/jour/article/view/1632 kostenfrei https://doaj.org/toc/0042-4625 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 179 2021 6 24-33
allfields_unstemmed	10.24884/0042-4625-2020-179-6-24-33 doi (DE-627)DOAJ021811334 (DE-599)DOAJ13bea76a88434d24a50bbfc079ccbf61 DE-627 ger DE-627 rakwb rus RD1-811 A. A. Skorokhod verfasserin aut Efficiency and safety of video-assisted mediastinal lymphadenectomy in the treatment of non-small cell lung cancer 2021 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier INTRODUCTION. A number of studies demonstrate the advantage of bilateral mediastinal lymphadenectomy in surgery of non-small cell lung cancer (nSCLC). For surgical approach to the opposite mediastinum for many years there were proposed sternotomy, video-thoracoscopy, and transcervical video-assisted interventions. In our practice, we use videoassisted mediastinal lymphadenectomy (VAMLA).The OBJECTIVE was to learn the efficiency and safety of VAMLA in surgery of NSCLC.METHODS AND MATERIALS. The study included the materials of examination and treatment of 102 patients with NSCLC. 102 patients were divided into 2 groups. In the 1st group (54 patients), VAMLA and lung resection were performed. In the 2nd group (48 patients): anatomical lung resection and systematic ipsilateral lymphadenectomy (SLD) were performed.RESULTS. The average number of remote lymph node stations in group 1 was (7.8±1.7); in group 2 – (4.5±1.2) (p<0.05). The average number of lymph nodes was 26±8.6 compared to (14.3±6) in both groups, respectively (p<0.05). «Occult» pN2-N3 metastasis was detected in 20 % (7/34) of patients of the group 1 and 6.5 % (2/31) of patients of the group 2 (p<0.05). The level of postoperative complications in both groups was 33.4 vs. 29.2 %, respectively (p>0.05). The duration of the postoperative day ((12.7±4.9) vs. (13.7±6.5)) and the duration of pleural drainage ((5.5±4.2) vs. (5.8±4.4)) did not differ in both groups (p>0.05).CONCLUSION. VAMLA is an effective and safe method for evaluating the pN stage of NSCLC. Performing VAMLA in left-sided NSCLC allows removing significantly more lymph nodes and stations in comparison with SLD available in VATS and thoracotomy, which increases the accuracy of postoperative N-staging. The use of the VAMLA in minimally invasive surgery of right-sided NSCLC may be promising in cases of high risk of «occult» pN3 lesion, but requires further study of the role of contralateral lymphatic dissection. video-assisted mediastinal lymphadenectomy vamla bilateral lymphatic dissection non-small cell lung cancer lung resection surgical treatment Surgery A. S. Petrov verfasserin aut A. R. Kozak verfasserin aut M. A. Atyukov verfasserin aut A. O. Nefedov verfasserin aut P. K. Yаblonskiy verfasserin aut In Вестник хирургии имени И.И. Грекова Pavlov First Saint Petersburg State Medical University, 2019 179(2021), 6, Seite 24-33 (DE-627)1697861369 00424625 nnns volume:179 year:2021 number:6 pages:24-33 https://doi.org/10.24884/0042-4625-2020-179-6-24-33 kostenfrei https://doaj.org/article/13bea76a88434d24a50bbfc079ccbf61 kostenfrei https://www.vestnik-grekova.ru/jour/article/view/1632 kostenfrei https://doaj.org/toc/0042-4625 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 179 2021 6 24-33
allfieldsGer	10.24884/0042-4625-2020-179-6-24-33 doi (DE-627)DOAJ021811334 (DE-599)DOAJ13bea76a88434d24a50bbfc079ccbf61 DE-627 ger DE-627 rakwb rus RD1-811 A. A. Skorokhod verfasserin aut Efficiency and safety of video-assisted mediastinal lymphadenectomy in the treatment of non-small cell lung cancer 2021 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier INTRODUCTION. A number of studies demonstrate the advantage of bilateral mediastinal lymphadenectomy in surgery of non-small cell lung cancer (nSCLC). For surgical approach to the opposite mediastinum for many years there were proposed sternotomy, video-thoracoscopy, and transcervical video-assisted interventions. In our practice, we use videoassisted mediastinal lymphadenectomy (VAMLA).The OBJECTIVE was to learn the efficiency and safety of VAMLA in surgery of NSCLC.METHODS AND MATERIALS. The study included the materials of examination and treatment of 102 patients with NSCLC. 102 patients were divided into 2 groups. In the 1st group (54 patients), VAMLA and lung resection were performed. In the 2nd group (48 patients): anatomical lung resection and systematic ipsilateral lymphadenectomy (SLD) were performed.RESULTS. The average number of remote lymph node stations in group 1 was (7.8±1.7); in group 2 – (4.5±1.2) (p<0.05). The average number of lymph nodes was 26±8.6 compared to (14.3±6) in both groups, respectively (p<0.05). «Occult» pN2-N3 metastasis was detected in 20 % (7/34) of patients of the group 1 and 6.5 % (2/31) of patients of the group 2 (p<0.05). The level of postoperative complications in both groups was 33.4 vs. 29.2 %, respectively (p>0.05). The duration of the postoperative day ((12.7±4.9) vs. (13.7±6.5)) and the duration of pleural drainage ((5.5±4.2) vs. (5.8±4.4)) did not differ in both groups (p>0.05).CONCLUSION. VAMLA is an effective and safe method for evaluating the pN stage of NSCLC. Performing VAMLA in left-sided NSCLC allows removing significantly more lymph nodes and stations in comparison with SLD available in VATS and thoracotomy, which increases the accuracy of postoperative N-staging. The use of the VAMLA in minimally invasive surgery of right-sided NSCLC may be promising in cases of high risk of «occult» pN3 lesion, but requires further study of the role of contralateral lymphatic dissection. video-assisted mediastinal lymphadenectomy vamla bilateral lymphatic dissection non-small cell lung cancer lung resection surgical treatment Surgery A. S. Petrov verfasserin aut A. R. Kozak verfasserin aut M. A. Atyukov verfasserin aut A. O. Nefedov verfasserin aut P. K. Yаblonskiy verfasserin aut In Вестник хирургии имени И.И. Грекова Pavlov First Saint Petersburg State Medical University, 2019 179(2021), 6, Seite 24-33 (DE-627)1697861369 00424625 nnns volume:179 year:2021 number:6 pages:24-33 https://doi.org/10.24884/0042-4625-2020-179-6-24-33 kostenfrei https://doaj.org/article/13bea76a88434d24a50bbfc079ccbf61 kostenfrei https://www.vestnik-grekova.ru/jour/article/view/1632 kostenfrei https://doaj.org/toc/0042-4625 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 179 2021 6 24-33
allfieldsSound	10.24884/0042-4625-2020-179-6-24-33 doi (DE-627)DOAJ021811334 (DE-599)DOAJ13bea76a88434d24a50bbfc079ccbf61 DE-627 ger DE-627 rakwb rus RD1-811 A. A. Skorokhod verfasserin aut Efficiency and safety of video-assisted mediastinal lymphadenectomy in the treatment of non-small cell lung cancer 2021 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier INTRODUCTION. A number of studies demonstrate the advantage of bilateral mediastinal lymphadenectomy in surgery of non-small cell lung cancer (nSCLC). For surgical approach to the opposite mediastinum for many years there were proposed sternotomy, video-thoracoscopy, and transcervical video-assisted interventions. In our practice, we use videoassisted mediastinal lymphadenectomy (VAMLA).The OBJECTIVE was to learn the efficiency and safety of VAMLA in surgery of NSCLC.METHODS AND MATERIALS. The study included the materials of examination and treatment of 102 patients with NSCLC. 102 patients were divided into 2 groups. In the 1st group (54 patients), VAMLA and lung resection were performed. In the 2nd group (48 patients): anatomical lung resection and systematic ipsilateral lymphadenectomy (SLD) were performed.RESULTS. The average number of remote lymph node stations in group 1 was (7.8±1.7); in group 2 – (4.5±1.2) (p<0.05). The average number of lymph nodes was 26±8.6 compared to (14.3±6) in both groups, respectively (p<0.05). «Occult» pN2-N3 metastasis was detected in 20 % (7/34) of patients of the group 1 and 6.5 % (2/31) of patients of the group 2 (p<0.05). The level of postoperative complications in both groups was 33.4 vs. 29.2 %, respectively (p>0.05). The duration of the postoperative day ((12.7±4.9) vs. (13.7±6.5)) and the duration of pleural drainage ((5.5±4.2) vs. (5.8±4.4)) did not differ in both groups (p>0.05).CONCLUSION. VAMLA is an effective and safe method for evaluating the pN stage of NSCLC. Performing VAMLA in left-sided NSCLC allows removing significantly more lymph nodes and stations in comparison with SLD available in VATS and thoracotomy, which increases the accuracy of postoperative N-staging. The use of the VAMLA in minimally invasive surgery of right-sided NSCLC may be promising in cases of high risk of «occult» pN3 lesion, but requires further study of the role of contralateral lymphatic dissection. video-assisted mediastinal lymphadenectomy vamla bilateral lymphatic dissection non-small cell lung cancer lung resection surgical treatment Surgery A. S. Petrov verfasserin aut A. R. Kozak verfasserin aut M. A. Atyukov verfasserin aut A. O. Nefedov verfasserin aut P. K. Yаblonskiy verfasserin aut In Вестник хирургии имени И.И. Грекова Pavlov First Saint Petersburg State Medical University, 2019 179(2021), 6, Seite 24-33 (DE-627)1697861369 00424625 nnns volume:179 year:2021 number:6 pages:24-33 https://doi.org/10.24884/0042-4625-2020-179-6-24-33 kostenfrei https://doaj.org/article/13bea76a88434d24a50bbfc079ccbf61 kostenfrei https://www.vestnik-grekova.ru/jour/article/view/1632 kostenfrei https://doaj.org/toc/0042-4625 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 179 2021 6 24-33
language	Russian
source	In Вестник хирургии имени И.И. Грекова 179(2021), 6, Seite 24-33 volume:179 year:2021 number:6 pages:24-33
sourceStr	In Вестник хирургии имени И.И. Грекова 179(2021), 6, Seite 24-33 volume:179 year:2021 number:6 pages:24-33
format_phy_str_mv	Article
institution	findex.gbv.de
topic_facet	video-assisted mediastinal lymphadenectomy vamla bilateral lymphatic dissection non-small cell lung cancer lung resection surgical treatment Surgery
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container_title	Вестник хирургии имени И.И. Грекова
authorswithroles_txt_mv	A. A. Skorokhod @@aut@@ A. S. Petrov @@aut@@ A. R. Kozak @@aut@@ M. A. Atyukov @@aut@@ A. O. Nefedov @@aut@@ P. K. Yаblonskiy @@aut@@
publishDateDaySort_date	2021-01-01T00:00:00Z
hierarchy_top_id	1697861369
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A. Skorokhod</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Efficiency and safety of video-assisted mediastinal lymphadenectomy in the treatment of non-small cell lung cancer</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="c">2021</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">Text</subfield><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">Computermedien</subfield><subfield code="b">c</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">Online-Ressource</subfield><subfield code="b">cr</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">INTRODUCTION. A number of studies demonstrate the advantage of bilateral mediastinal lymphadenectomy in surgery of non-small cell lung cancer (nSCLC). For surgical approach to the opposite mediastinum for many years there were proposed sternotomy, video-thoracoscopy, and transcervical video-assisted interventions. In our practice, we use videoassisted mediastinal lymphadenectomy (VAMLA).The OBJECTIVE was to learn the efficiency and safety of VAMLA in surgery of NSCLC.METHODS AND MATERIALS. The study included the materials of examination and treatment of 102 patients with NSCLC. 102 patients were divided into 2 groups. In the 1st group (54 patients), VAMLA and lung resection were performed. In the 2nd group (48 patients): anatomical lung resection and systematic ipsilateral lymphadenectomy (SLD) were performed.RESULTS. The average number of remote lymph node stations in group 1 was (7.8±1.7); in group 2 – (4.5±1.2) (p&lt;0.05). The average number of lymph nodes was 26±8.6 compared to (14.3±6) in both groups, respectively (p&lt;0.05). «Occult» pN2-N3 metastasis was detected in 20 % (7/34) of patients of the group 1 and 6.5 % (2/31) of patients of the group 2 (p&lt;0.05). The level of postoperative complications in both groups was 33.4 vs. 29.2 %, respectively (p&gt;0.05). The duration of the postoperative day ((12.7±4.9) vs. (13.7±6.5)) and the duration of pleural drainage ((5.5±4.2) vs. (5.8±4.4)) did not differ in both groups (p&gt;0.05).CONCLUSION. VAMLA is an effective and safe method for evaluating the pN stage of NSCLC. Performing VAMLA in left-sided NSCLC allows removing significantly more lymph nodes and stations in comparison with SLD available in VATS and thoracotomy, which increases the accuracy of postoperative N-staging. 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callnumber-first	R - Medicine
author	A. A. Skorokhod
spellingShingle	A. A. Skorokhod misc RD1-811 misc video-assisted mediastinal lymphadenectomy misc vamla misc bilateral lymphatic dissection misc non-small cell lung cancer misc lung resection misc surgical treatment misc Surgery Efficiency and safety of video-assisted mediastinal lymphadenectomy in the treatment of non-small cell lung cancer
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topic_title	RD1-811 Efficiency and safety of video-assisted mediastinal lymphadenectomy in the treatment of non-small cell lung cancer video-assisted mediastinal lymphadenectomy vamla bilateral lymphatic dissection non-small cell lung cancer lung resection surgical treatment
topic	misc RD1-811 misc video-assisted mediastinal lymphadenectomy misc vamla misc bilateral lymphatic dissection misc non-small cell lung cancer misc lung resection misc surgical treatment misc Surgery
topic_unstemmed	misc RD1-811 misc video-assisted mediastinal lymphadenectomy misc vamla misc bilateral lymphatic dissection misc non-small cell lung cancer misc lung resection misc surgical treatment misc Surgery
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hierarchy_parent_title	Вестник хирургии имени И.И. Грекова
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title	Efficiency and safety of video-assisted mediastinal lymphadenectomy in the treatment of non-small cell lung cancer
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title_full	Efficiency and safety of video-assisted mediastinal lymphadenectomy in the treatment of non-small cell lung cancer
author_sort	A. A. Skorokhod
journal	Вестник хирургии имени И.И. Грекова
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author_browse	A. A. Skorokhod A. S. Petrov A. R. Kozak M. A. Atyukov A. O. Nefedov P. K. Yаblonskiy
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doi_str_mv	10.24884/0042-4625-2020-179-6-24-33
author2-role	verfasserin
title_sort	efficiency and safety of video-assisted mediastinal lymphadenectomy in the treatment of non-small cell lung cancer
callnumber	RD1-811
title_auth	Efficiency and safety of video-assisted mediastinal lymphadenectomy in the treatment of non-small cell lung cancer
abstract	INTRODUCTION. A number of studies demonstrate the advantage of bilateral mediastinal lymphadenectomy in surgery of non-small cell lung cancer (nSCLC). For surgical approach to the opposite mediastinum for many years there were proposed sternotomy, video-thoracoscopy, and transcervical video-assisted interventions. In our practice, we use videoassisted mediastinal lymphadenectomy (VAMLA).The OBJECTIVE was to learn the efficiency and safety of VAMLA in surgery of NSCLC.METHODS AND MATERIALS. The study included the materials of examination and treatment of 102 patients with NSCLC. 102 patients were divided into 2 groups. In the 1st group (54 patients), VAMLA and lung resection were performed. In the 2nd group (48 patients): anatomical lung resection and systematic ipsilateral lymphadenectomy (SLD) were performed.RESULTS. The average number of remote lymph node stations in group 1 was (7.8±1.7); in group 2 – (4.5±1.2) (p<0.05). The average number of lymph nodes was 26±8.6 compared to (14.3±6) in both groups, respectively (p<0.05). «Occult» pN2-N3 metastasis was detected in 20 % (7/34) of patients of the group 1 and 6.5 % (2/31) of patients of the group 2 (p<0.05). The level of postoperative complications in both groups was 33.4 vs. 29.2 %, respectively (p>0.05). The duration of the postoperative day ((12.7±4.9) vs. (13.7±6.5)) and the duration of pleural drainage ((5.5±4.2) vs. (5.8±4.4)) did not differ in both groups (p>0.05).CONCLUSION. VAMLA is an effective and safe method for evaluating the pN stage of NSCLC. Performing VAMLA in left-sided NSCLC allows removing significantly more lymph nodes and stations in comparison with SLD available in VATS and thoracotomy, which increases the accuracy of postoperative N-staging. The use of the VAMLA in minimally invasive surgery of right-sided NSCLC may be promising in cases of high risk of «occult» pN3 lesion, but requires further study of the role of contralateral lymphatic dissection.
abstractGer	INTRODUCTION. A number of studies demonstrate the advantage of bilateral mediastinal lymphadenectomy in surgery of non-small cell lung cancer (nSCLC). For surgical approach to the opposite mediastinum for many years there were proposed sternotomy, video-thoracoscopy, and transcervical video-assisted interventions. In our practice, we use videoassisted mediastinal lymphadenectomy (VAMLA).The OBJECTIVE was to learn the efficiency and safety of VAMLA in surgery of NSCLC.METHODS AND MATERIALS. The study included the materials of examination and treatment of 102 patients with NSCLC. 102 patients were divided into 2 groups. In the 1st group (54 patients), VAMLA and lung resection were performed. In the 2nd group (48 patients): anatomical lung resection and systematic ipsilateral lymphadenectomy (SLD) were performed.RESULTS. The average number of remote lymph node stations in group 1 was (7.8±1.7); in group 2 – (4.5±1.2) (p<0.05). The average number of lymph nodes was 26±8.6 compared to (14.3±6) in both groups, respectively (p<0.05). «Occult» pN2-N3 metastasis was detected in 20 % (7/34) of patients of the group 1 and 6.5 % (2/31) of patients of the group 2 (p<0.05). The level of postoperative complications in both groups was 33.4 vs. 29.2 %, respectively (p>0.05). The duration of the postoperative day ((12.7±4.9) vs. (13.7±6.5)) and the duration of pleural drainage ((5.5±4.2) vs. (5.8±4.4)) did not differ in both groups (p>0.05).CONCLUSION. VAMLA is an effective and safe method for evaluating the pN stage of NSCLC. Performing VAMLA in left-sided NSCLC allows removing significantly more lymph nodes and stations in comparison with SLD available in VATS and thoracotomy, which increases the accuracy of postoperative N-staging. The use of the VAMLA in minimally invasive surgery of right-sided NSCLC may be promising in cases of high risk of «occult» pN3 lesion, but requires further study of the role of contralateral lymphatic dissection.
abstract_unstemmed	INTRODUCTION. A number of studies demonstrate the advantage of bilateral mediastinal lymphadenectomy in surgery of non-small cell lung cancer (nSCLC). For surgical approach to the opposite mediastinum for many years there were proposed sternotomy, video-thoracoscopy, and transcervical video-assisted interventions. In our practice, we use videoassisted mediastinal lymphadenectomy (VAMLA).The OBJECTIVE was to learn the efficiency and safety of VAMLA in surgery of NSCLC.METHODS AND MATERIALS. The study included the materials of examination and treatment of 102 patients with NSCLC. 102 patients were divided into 2 groups. In the 1st group (54 patients), VAMLA and lung resection were performed. In the 2nd group (48 patients): anatomical lung resection and systematic ipsilateral lymphadenectomy (SLD) were performed.RESULTS. The average number of remote lymph node stations in group 1 was (7.8±1.7); in group 2 – (4.5±1.2) (p<0.05). The average number of lymph nodes was 26±8.6 compared to (14.3±6) in both groups, respectively (p<0.05). «Occult» pN2-N3 metastasis was detected in 20 % (7/34) of patients of the group 1 and 6.5 % (2/31) of patients of the group 2 (p<0.05). The level of postoperative complications in both groups was 33.4 vs. 29.2 %, respectively (p>0.05). The duration of the postoperative day ((12.7±4.9) vs. (13.7±6.5)) and the duration of pleural drainage ((5.5±4.2) vs. (5.8±4.4)) did not differ in both groups (p>0.05).CONCLUSION. VAMLA is an effective and safe method for evaluating the pN stage of NSCLC. Performing VAMLA in left-sided NSCLC allows removing significantly more lymph nodes and stations in comparison with SLD available in VATS and thoracotomy, which increases the accuracy of postoperative N-staging. The use of the VAMLA in minimally invasive surgery of right-sided NSCLC may be promising in cases of high risk of «occult» pN3 lesion, but requires further study of the role of contralateral lymphatic dissection.
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title_short	Efficiency and safety of video-assisted mediastinal lymphadenectomy in the treatment of non-small cell lung cancer
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Efficiency and safety of video-assisted mediastinal lymphadenectomy in the treatment of non-small cell lung cancer

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