Vitamin K-dependent proteins: osteocalcin, matrix Gla-protein and extra osseous effects
Vitamin K - is a fat-soluble vitamin which plays an important role in the metabolism of bone and connective tissue, maintenance blood clotting properties. Vitamin K is involved in carboxylation of glutamic acid residues in the polypeptide chains of 14 human proteins, providing them with the necessar...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Yu В Pankratova [verfasserIn] E A Pigarova [verfasserIn] L K Dzeranova [verfasserIn] |
|---|
| Format: |
E-Artikel |
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| Sprache: |
Englisch ; Russisch |
| Erschienen: |
2013 |
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| Schlagwörter: |
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| Übergeordnetes Werk: |
In: Ожирение и метаболизм ; 10(2013), 2, Seite 11-18 volume:10 ; year:2013 ; number:2 ; pages:11-18 |
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| Links: |
Link aufrufen |
|---|
| DOI / URN: |
10.14341/2071-8713-4818 |
|---|
| Katalog-ID: |
DOAJ022675698 |
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| 520 | |a Vitamin K - is a fat-soluble vitamin which plays an important role in the metabolism of bone and connective tissue, maintenance blood clotting properties. Vitamin K is involved in carboxylation of glutamic acid residues in the polypeptide chains of 14 human proteins, providing them with the necessary functional properties. Lack of vitamin K-dependent carboxylation of these proteins leads to changes in their biological activity. In this literature review we cover the mechanisms of vitamin K-dependent carboxylation and none bone actions of osteocalcin and matrix Gla-protein with different degrees of carboxylation. | ||
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Vitamin K - is a fat-soluble vitamin which plays an important role in the metabolism of bone and connective tissue, maintenance blood clotting properties. Vitamin K is involved in carboxylation of glutamic acid residues in the polypeptide chains of 14 human proteins, providing them with the necessary functional properties. Lack of vitamin K-dependent carboxylation of these proteins leads to changes in their biological activity. In this literature review we cover the mechanisms of vitamin K-dependent carboxylation and none bone actions of osteocalcin and matrix Gla-protein with different degrees of carboxylation. |
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Vitamin K - is a fat-soluble vitamin which plays an important role in the metabolism of bone and connective tissue, maintenance blood clotting properties. Vitamin K is involved in carboxylation of glutamic acid residues in the polypeptide chains of 14 human proteins, providing them with the necessary functional properties. Lack of vitamin K-dependent carboxylation of these proteins leads to changes in their biological activity. In this literature review we cover the mechanisms of vitamin K-dependent carboxylation and none bone actions of osteocalcin and matrix Gla-protein with different degrees of carboxylation. |
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Vitamin K - is a fat-soluble vitamin which plays an important role in the metabolism of bone and connective tissue, maintenance blood clotting properties. Vitamin K is involved in carboxylation of glutamic acid residues in the polypeptide chains of 14 human proteins, providing them with the necessary functional properties. Lack of vitamin K-dependent carboxylation of these proteins leads to changes in their biological activity. In this literature review we cover the mechanisms of vitamin K-dependent carboxylation and none bone actions of osteocalcin and matrix Gla-protein with different degrees of carboxylation. |
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