The Effects of Sufentanil or Remifentanil Pretreatment on Propofol Injection Pain

Abstract Background and purpose: Propofol produces anesthesia with rapid recovery. However, it causes pain or discomfort during injection. The effect of remifentanil in prevention of propofol-induced injection pain was demonstrated in earlier studies. Sufentanil, an opioid analgesic, has not been st...
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Autor*in:	M.R. Safavi, M.D. [verfasserIn]  A. Honarmand, M.D [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch ; Persisch

Erschienen:	2007

Schlagwörter:	Propofol Remifentanil Sufentanil Injection pain

Übergeordnetes Werk:	In: Journal of Mazandaran University of Medical Sciences - Mazandaran University of Medical Sciences, 2018, 17(2007), 59, Seite 35-41
Übergeordnetes Werk:	volume:17 ; year:2007 ; number:59 ; pages:35-41

Links:	Link aufrufen Link aufrufen Journal toc

Katalog-ID:	DOAJ022753230

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245	1	4	\|a The Effects of Sufentanil or Remifentanil Pretreatment on Propofol Injection Pain
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520			\|a Abstract Background and purpose: Propofol produces anesthesia with rapid recovery. However, it causes pain or discomfort during injection. The effect of remifentanil in prevention of propofol-induced injection pain was demonstrated in earlier studies. Sufentanil, an opioid analgesic, has not been studied for managing pain on injection of propofol. We have compared the efficacy of remifentanil and sufentanil for the prevention of propofol induced pain.Materials and Methods: One hundred twenty American Society of Anesthesiologists (ASA) class I-II adults undergoing elective surgery were randomly assigned into four groups of 20 each. Patients received 2 mL (10 mg) sufentanil, 2 mL of remifentanil (10 mg), 2 mL of remifentanil (20 mg), or 2 mL of saline 60 seconds prior to administering 5 mL of propofol 1%. Patients were asked whether they had pain due to propofol injection.Their pain scores were evaluated with the use of the four-point scale of Ambesh.Results: The remifentanil and sufentanil groups significantly showed lower frequency of pain than that in the saline group (p < 0.05). Median pain intensity scores were significantly lower in the group receiving remifentanil 20 mg compared with the sufentanil groups (P < 0.05). The median intensity of propofol-induced pain was statistically similar between the groups receiving sufentanil or remifentanil 10 mg and the placebo groups.Conclusion: Remifentanil 20 mg over 1 min before propofol administration is more effective than sufentanil 10 mg 1 min prior to propofol in reducing the incidence and intensity of injection pain.
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allfields	(DE-627)DOAJ022753230 (DE-599)DOAJ297fc1826ea8461d9ac2e7f0e23c95e0 DE-627 ger DE-627 rakwb eng per R5-920 M.R. Safavi, M.D. verfasserin aut The Effects of Sufentanil or Remifentanil Pretreatment on Propofol Injection Pain 2007 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract Background and purpose: Propofol produces anesthesia with rapid recovery. However, it causes pain or discomfort during injection. The effect of remifentanil in prevention of propofol-induced injection pain was demonstrated in earlier studies. Sufentanil, an opioid analgesic, has not been studied for managing pain on injection of propofol. We have compared the efficacy of remifentanil and sufentanil for the prevention of propofol induced pain.Materials and Methods: One hundred twenty American Society of Anesthesiologists (ASA) class I-II adults undergoing elective surgery were randomly assigned into four groups of 20 each. Patients received 2 mL (10 mg) sufentanil, 2 mL of remifentanil (10 mg), 2 mL of remifentanil (20 mg), or 2 mL of saline 60 seconds prior to administering 5 mL of propofol 1%. Patients were asked whether they had pain due to propofol injection.Their pain scores were evaluated with the use of the four-point scale of Ambesh.Results: The remifentanil and sufentanil groups significantly showed lower frequency of pain than that in the saline group (p < 0.05). Median pain intensity scores were significantly lower in the group receiving remifentanil 20 mg compared with the sufentanil groups (P < 0.05). The median intensity of propofol-induced pain was statistically similar between the groups receiving sufentanil or remifentanil 10 mg and the placebo groups.Conclusion: Remifentanil 20 mg over 1 min before propofol administration is more effective than sufentanil 10 mg 1 min prior to propofol in reducing the incidence and intensity of injection pain. Propofol Remifentanil Sufentanil Injection pain Medicine R Medicine (General)  A. Honarmand, M.D verfasserin aut In Journal of Mazandaran University of Medical Sciences Mazandaran University of Medical Sciences, 2018 17(2007), 59, Seite 35-41 (DE-627)59095623X (DE-600)2476989-7 17359279 nnns volume:17 year:2007 number:59 pages:35-41 https://doaj.org/article/297fc1826ea8461d9ac2e7f0e23c95e0 kostenfrei http://www.mazums.ac.ir/index.php?digital_library&do=downloadPdf&sid=511 kostenfrei https://doaj.org/toc/1735-9260 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 17 2007 59 35-41
spelling	(DE-627)DOAJ022753230 (DE-599)DOAJ297fc1826ea8461d9ac2e7f0e23c95e0 DE-627 ger DE-627 rakwb eng per R5-920 M.R. Safavi, M.D. verfasserin aut The Effects of Sufentanil or Remifentanil Pretreatment on Propofol Injection Pain 2007 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract Background and purpose: Propofol produces anesthesia with rapid recovery. However, it causes pain or discomfort during injection. The effect of remifentanil in prevention of propofol-induced injection pain was demonstrated in earlier studies. Sufentanil, an opioid analgesic, has not been studied for managing pain on injection of propofol. We have compared the efficacy of remifentanil and sufentanil for the prevention of propofol induced pain.Materials and Methods: One hundred twenty American Society of Anesthesiologists (ASA) class I-II adults undergoing elective surgery were randomly assigned into four groups of 20 each. Patients received 2 mL (10 mg) sufentanil, 2 mL of remifentanil (10 mg), 2 mL of remifentanil (20 mg), or 2 mL of saline 60 seconds prior to administering 5 mL of propofol 1%. Patients were asked whether they had pain due to propofol injection.Their pain scores were evaluated with the use of the four-point scale of Ambesh.Results: The remifentanil and sufentanil groups significantly showed lower frequency of pain than that in the saline group (p < 0.05). Median pain intensity scores were significantly lower in the group receiving remifentanil 20 mg compared with the sufentanil groups (P < 0.05). The median intensity of propofol-induced pain was statistically similar between the groups receiving sufentanil or remifentanil 10 mg and the placebo groups.Conclusion: Remifentanil 20 mg over 1 min before propofol administration is more effective than sufentanil 10 mg 1 min prior to propofol in reducing the incidence and intensity of injection pain. Propofol Remifentanil Sufentanil Injection pain Medicine R Medicine (General)  A. Honarmand, M.D verfasserin aut In Journal of Mazandaran University of Medical Sciences Mazandaran University of Medical Sciences, 2018 17(2007), 59, Seite 35-41 (DE-627)59095623X (DE-600)2476989-7 17359279 nnns volume:17 year:2007 number:59 pages:35-41 https://doaj.org/article/297fc1826ea8461d9ac2e7f0e23c95e0 kostenfrei http://www.mazums.ac.ir/index.php?digital_library&do=downloadPdf&sid=511 kostenfrei https://doaj.org/toc/1735-9260 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 17 2007 59 35-41
allfields_unstemmed	(DE-627)DOAJ022753230 (DE-599)DOAJ297fc1826ea8461d9ac2e7f0e23c95e0 DE-627 ger DE-627 rakwb eng per R5-920 M.R. Safavi, M.D. verfasserin aut The Effects of Sufentanil or Remifentanil Pretreatment on Propofol Injection Pain 2007 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract Background and purpose: Propofol produces anesthesia with rapid recovery. However, it causes pain or discomfort during injection. The effect of remifentanil in prevention of propofol-induced injection pain was demonstrated in earlier studies. Sufentanil, an opioid analgesic, has not been studied for managing pain on injection of propofol. We have compared the efficacy of remifentanil and sufentanil for the prevention of propofol induced pain.Materials and Methods: One hundred twenty American Society of Anesthesiologists (ASA) class I-II adults undergoing elective surgery were randomly assigned into four groups of 20 each. Patients received 2 mL (10 mg) sufentanil, 2 mL of remifentanil (10 mg), 2 mL of remifentanil (20 mg), or 2 mL of saline 60 seconds prior to administering 5 mL of propofol 1%. Patients were asked whether they had pain due to propofol injection.Their pain scores were evaluated with the use of the four-point scale of Ambesh.Results: The remifentanil and sufentanil groups significantly showed lower frequency of pain than that in the saline group (p < 0.05). Median pain intensity scores were significantly lower in the group receiving remifentanil 20 mg compared with the sufentanil groups (P < 0.05). The median intensity of propofol-induced pain was statistically similar between the groups receiving sufentanil or remifentanil 10 mg and the placebo groups.Conclusion: Remifentanil 20 mg over 1 min before propofol administration is more effective than sufentanil 10 mg 1 min prior to propofol in reducing the incidence and intensity of injection pain. Propofol Remifentanil Sufentanil Injection pain Medicine R Medicine (General)  A. Honarmand, M.D verfasserin aut In Journal of Mazandaran University of Medical Sciences Mazandaran University of Medical Sciences, 2018 17(2007), 59, Seite 35-41 (DE-627)59095623X (DE-600)2476989-7 17359279 nnns volume:17 year:2007 number:59 pages:35-41 https://doaj.org/article/297fc1826ea8461d9ac2e7f0e23c95e0 kostenfrei http://www.mazums.ac.ir/index.php?digital_library&do=downloadPdf&sid=511 kostenfrei https://doaj.org/toc/1735-9260 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 17 2007 59 35-41
allfieldsGer	(DE-627)DOAJ022753230 (DE-599)DOAJ297fc1826ea8461d9ac2e7f0e23c95e0 DE-627 ger DE-627 rakwb eng per R5-920 M.R. Safavi, M.D. verfasserin aut The Effects of Sufentanil or Remifentanil Pretreatment on Propofol Injection Pain 2007 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract Background and purpose: Propofol produces anesthesia with rapid recovery. However, it causes pain or discomfort during injection. The effect of remifentanil in prevention of propofol-induced injection pain was demonstrated in earlier studies. Sufentanil, an opioid analgesic, has not been studied for managing pain on injection of propofol. We have compared the efficacy of remifentanil and sufentanil for the prevention of propofol induced pain.Materials and Methods: One hundred twenty American Society of Anesthesiologists (ASA) class I-II adults undergoing elective surgery were randomly assigned into four groups of 20 each. Patients received 2 mL (10 mg) sufentanil, 2 mL of remifentanil (10 mg), 2 mL of remifentanil (20 mg), or 2 mL of saline 60 seconds prior to administering 5 mL of propofol 1%. Patients were asked whether they had pain due to propofol injection.Their pain scores were evaluated with the use of the four-point scale of Ambesh.Results: The remifentanil and sufentanil groups significantly showed lower frequency of pain than that in the saline group (p < 0.05). Median pain intensity scores were significantly lower in the group receiving remifentanil 20 mg compared with the sufentanil groups (P < 0.05). The median intensity of propofol-induced pain was statistically similar between the groups receiving sufentanil or remifentanil 10 mg and the placebo groups.Conclusion: Remifentanil 20 mg over 1 min before propofol administration is more effective than sufentanil 10 mg 1 min prior to propofol in reducing the incidence and intensity of injection pain. Propofol Remifentanil Sufentanil Injection pain Medicine R Medicine (General)  A. Honarmand, M.D verfasserin aut In Journal of Mazandaran University of Medical Sciences Mazandaran University of Medical Sciences, 2018 17(2007), 59, Seite 35-41 (DE-627)59095623X (DE-600)2476989-7 17359279 nnns volume:17 year:2007 number:59 pages:35-41 https://doaj.org/article/297fc1826ea8461d9ac2e7f0e23c95e0 kostenfrei http://www.mazums.ac.ir/index.php?digital_library&do=downloadPdf&sid=511 kostenfrei https://doaj.org/toc/1735-9260 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 17 2007 59 35-41
allfieldsSound	(DE-627)DOAJ022753230 (DE-599)DOAJ297fc1826ea8461d9ac2e7f0e23c95e0 DE-627 ger DE-627 rakwb eng per R5-920 M.R. Safavi, M.D. verfasserin aut The Effects of Sufentanil or Remifentanil Pretreatment on Propofol Injection Pain 2007 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Abstract Background and purpose: Propofol produces anesthesia with rapid recovery. However, it causes pain or discomfort during injection. The effect of remifentanil in prevention of propofol-induced injection pain was demonstrated in earlier studies. Sufentanil, an opioid analgesic, has not been studied for managing pain on injection of propofol. We have compared the efficacy of remifentanil and sufentanil for the prevention of propofol induced pain.Materials and Methods: One hundred twenty American Society of Anesthesiologists (ASA) class I-II adults undergoing elective surgery were randomly assigned into four groups of 20 each. Patients received 2 mL (10 mg) sufentanil, 2 mL of remifentanil (10 mg), 2 mL of remifentanil (20 mg), or 2 mL of saline 60 seconds prior to administering 5 mL of propofol 1%. Patients were asked whether they had pain due to propofol injection.Their pain scores were evaluated with the use of the four-point scale of Ambesh.Results: The remifentanil and sufentanil groups significantly showed lower frequency of pain than that in the saline group (p < 0.05). Median pain intensity scores were significantly lower in the group receiving remifentanil 20 mg compared with the sufentanil groups (P < 0.05). The median intensity of propofol-induced pain was statistically similar between the groups receiving sufentanil or remifentanil 10 mg and the placebo groups.Conclusion: Remifentanil 20 mg over 1 min before propofol administration is more effective than sufentanil 10 mg 1 min prior to propofol in reducing the incidence and intensity of injection pain. Propofol Remifentanil Sufentanil Injection pain Medicine R Medicine (General)  A. Honarmand, M.D verfasserin aut In Journal of Mazandaran University of Medical Sciences Mazandaran University of Medical Sciences, 2018 17(2007), 59, Seite 35-41 (DE-627)59095623X (DE-600)2476989-7 17359279 nnns volume:17 year:2007 number:59 pages:35-41 https://doaj.org/article/297fc1826ea8461d9ac2e7f0e23c95e0 kostenfrei http://www.mazums.ac.ir/index.php?digital_library&do=downloadPdf&sid=511 kostenfrei https://doaj.org/toc/1735-9260 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 17 2007 59 35-41
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Safavi, M.D.</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="4"><subfield code="a">The Effects of Sufentanil or Remifentanil Pretreatment on Propofol Injection Pain</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="c">2007</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">Text</subfield><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">Computermedien</subfield><subfield code="b">c</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">Online-Ressource</subfield><subfield code="b">cr</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">Abstract Background and purpose: Propofol produces anesthesia with rapid recovery. However, it causes pain or discomfort during injection. The effect of remifentanil in prevention of propofol-induced injection pain was demonstrated in earlier studies. Sufentanil, an opioid analgesic, has not been studied for managing pain on injection of propofol. We have compared the efficacy of remifentanil and sufentanil for the prevention of propofol induced pain.Materials and Methods: One hundred twenty American Society of Anesthesiologists (ASA) class I-II adults undergoing elective surgery were randomly assigned into four groups of 20 each. Patients received 2 mL (10 mg) sufentanil, 2 mL of remifentanil (10 mg), 2 mL of remifentanil (20 mg), or 2 mL of saline 60 seconds prior to administering 5 mL of propofol 1%. Patients were asked whether they had pain due to propofol injection.Their pain scores were evaluated with the use of the four-point scale of Ambesh.Results: The remifentanil and sufentanil groups significantly showed lower frequency of pain than that in the saline group (p < 0.05). Median pain intensity scores were significantly lower in the group receiving remifentanil 20 mg compared with the sufentanil groups (P < 0.05). The median intensity of propofol-induced pain was statistically similar between the groups receiving sufentanil or remifentanil 10 mg and the placebo groups.Conclusion: Remifentanil 20 mg over 1 min before propofol administration is more effective than sufentanil 10 mg 1 min prior to propofol in reducing the incidence and intensity of injection pain.</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Propofol</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Remifentanil</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Sufentanil</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Injection pain</subfield></datafield><datafield tag="653" ind1=" " ind2="0"><subfield code="a">Medicine</subfield></datafield><datafield tag="653" ind1=" " ind2="0"><subfield code="a">R</subfield></datafield><datafield tag="653" ind1=" " ind2="0"><subfield code="a">Medicine (General)</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a"> A. 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callnumber-first	R - Medicine
author	M.R. Safavi, M.D.
spellingShingle	M.R. Safavi, M.D. misc R5-920 misc Propofol misc Remifentanil misc Sufentanil misc Injection pain misc Medicine misc R misc Medicine (General) The Effects of Sufentanil or Remifentanil Pretreatment on Propofol Injection Pain
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topic_title	R5-920 The Effects of Sufentanil or Remifentanil Pretreatment on Propofol Injection Pain Propofol Remifentanil Sufentanil Injection pain
topic	misc R5-920 misc Propofol misc Remifentanil misc Sufentanil misc Injection pain misc Medicine misc R misc Medicine (General)
topic_unstemmed	misc R5-920 misc Propofol misc Remifentanil misc Sufentanil misc Injection pain misc Medicine misc R misc Medicine (General)
topic_browse	misc R5-920 misc Propofol misc Remifentanil misc Sufentanil misc Injection pain misc Medicine misc R misc Medicine (General)
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title	The Effects of Sufentanil or Remifentanil Pretreatment on Propofol Injection Pain
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title_full	The Effects of Sufentanil or Remifentanil Pretreatment on Propofol Injection Pain
author_sort	M.R. Safavi, M.D.
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author_browse	M.R. Safavi, M.D.  A. Honarmand, M.D
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author-letter	M.R. Safavi, M.D.
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title_sort	effects of sufentanil or remifentanil pretreatment on propofol injection pain
callnumber	R5-920
title_auth	The Effects of Sufentanil or Remifentanil Pretreatment on Propofol Injection Pain
abstract	Abstract Background and purpose: Propofol produces anesthesia with rapid recovery. However, it causes pain or discomfort during injection. The effect of remifentanil in prevention of propofol-induced injection pain was demonstrated in earlier studies. Sufentanil, an opioid analgesic, has not been studied for managing pain on injection of propofol. We have compared the efficacy of remifentanil and sufentanil for the prevention of propofol induced pain.Materials and Methods: One hundred twenty American Society of Anesthesiologists (ASA) class I-II adults undergoing elective surgery were randomly assigned into four groups of 20 each. Patients received 2 mL (10 mg) sufentanil, 2 mL of remifentanil (10 mg), 2 mL of remifentanil (20 mg), or 2 mL of saline 60 seconds prior to administering 5 mL of propofol 1%. Patients were asked whether they had pain due to propofol injection.Their pain scores were evaluated with the use of the four-point scale of Ambesh.Results: The remifentanil and sufentanil groups significantly showed lower frequency of pain than that in the saline group (p < 0.05). Median pain intensity scores were significantly lower in the group receiving remifentanil 20 mg compared with the sufentanil groups (P < 0.05). The median intensity of propofol-induced pain was statistically similar between the groups receiving sufentanil or remifentanil 10 mg and the placebo groups.Conclusion: Remifentanil 20 mg over 1 min before propofol administration is more effective than sufentanil 10 mg 1 min prior to propofol in reducing the incidence and intensity of injection pain.
abstractGer	Abstract Background and purpose: Propofol produces anesthesia with rapid recovery. However, it causes pain or discomfort during injection. The effect of remifentanil in prevention of propofol-induced injection pain was demonstrated in earlier studies. Sufentanil, an opioid analgesic, has not been studied for managing pain on injection of propofol. We have compared the efficacy of remifentanil and sufentanil for the prevention of propofol induced pain.Materials and Methods: One hundred twenty American Society of Anesthesiologists (ASA) class I-II adults undergoing elective surgery were randomly assigned into four groups of 20 each. Patients received 2 mL (10 mg) sufentanil, 2 mL of remifentanil (10 mg), 2 mL of remifentanil (20 mg), or 2 mL of saline 60 seconds prior to administering 5 mL of propofol 1%. Patients were asked whether they had pain due to propofol injection.Their pain scores were evaluated with the use of the four-point scale of Ambesh.Results: The remifentanil and sufentanil groups significantly showed lower frequency of pain than that in the saline group (p < 0.05). Median pain intensity scores were significantly lower in the group receiving remifentanil 20 mg compared with the sufentanil groups (P < 0.05). The median intensity of propofol-induced pain was statistically similar between the groups receiving sufentanil or remifentanil 10 mg and the placebo groups.Conclusion: Remifentanil 20 mg over 1 min before propofol administration is more effective than sufentanil 10 mg 1 min prior to propofol in reducing the incidence and intensity of injection pain.
abstract_unstemmed	Abstract Background and purpose: Propofol produces anesthesia with rapid recovery. However, it causes pain or discomfort during injection. The effect of remifentanil in prevention of propofol-induced injection pain was demonstrated in earlier studies. Sufentanil, an opioid analgesic, has not been studied for managing pain on injection of propofol. We have compared the efficacy of remifentanil and sufentanil for the prevention of propofol induced pain.Materials and Methods: One hundred twenty American Society of Anesthesiologists (ASA) class I-II adults undergoing elective surgery were randomly assigned into four groups of 20 each. Patients received 2 mL (10 mg) sufentanil, 2 mL of remifentanil (10 mg), 2 mL of remifentanil (20 mg), or 2 mL of saline 60 seconds prior to administering 5 mL of propofol 1%. Patients were asked whether they had pain due to propofol injection.Their pain scores were evaluated with the use of the four-point scale of Ambesh.Results: The remifentanil and sufentanil groups significantly showed lower frequency of pain than that in the saline group (p < 0.05). Median pain intensity scores were significantly lower in the group receiving remifentanil 20 mg compared with the sufentanil groups (P < 0.05). The median intensity of propofol-induced pain was statistically similar between the groups receiving sufentanil or remifentanil 10 mg and the placebo groups.Conclusion: Remifentanil 20 mg over 1 min before propofol administration is more effective than sufentanil 10 mg 1 min prior to propofol in reducing the incidence and intensity of injection pain.
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title_short	The Effects of Sufentanil or Remifentanil Pretreatment on Propofol Injection Pain
url	https://doaj.org/article/297fc1826ea8461d9ac2e7f0e23c95e0 http://www.mazums.ac.ir/index.php?digital_library&do=downloadPdf&sid=511 https://doaj.org/toc/1735-9260
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Safavi, M.D.</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="4"><subfield code="a">The Effects of Sufentanil or Remifentanil Pretreatment on Propofol Injection Pain</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="c">2007</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">Text</subfield><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">Computermedien</subfield><subfield code="b">c</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">Online-Ressource</subfield><subfield code="b">cr</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">Abstract Background and purpose: Propofol produces anesthesia with rapid recovery. 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The median intensity of propofol-induced pain was statistically similar between the groups receiving sufentanil or remifentanil 10 mg and the placebo groups.Conclusion: Remifentanil 20 mg over 1 min before propofol administration is more effective than sufentanil 10 mg 1 min prior to propofol in reducing the incidence and intensity of injection pain.</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Propofol</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Remifentanil</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Sufentanil</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Injection pain</subfield></datafield><datafield tag="653" ind1=" " ind2="0"><subfield code="a">Medicine</subfield></datafield><datafield tag="653" ind1=" " ind2="0"><subfield code="a">R</subfield></datafield><datafield tag="653" ind1=" " ind2="0"><subfield code="a">Medicine (General)</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a"> A. 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The Effects of Sufentanil or Remifentanil Pretreatment on Propofol Injection Pain

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