Comparison of Sublingual Misoprostol and Manual Vacuum Aspiration for the Treatment of Incomplete Abortion in First Trimester in Terms of Frequency of Decreased Haemoglobin Levels

Background: To compare efficacy of manual vacuum aspiration with sublingual misoprostol for the treatment of incomplete abortion in terms of frequency of blood loss and decreased haemoglobin. Methods: In this randomized controlled trial, patients with incomplete abortion, open cervical os, vaginal b...
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Autor*in:	Saima Khurshid Ahmed [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2017

Schlagwörter:	Manual vacuum aspiration Manual vacuum aspirationHaemoglobin level Gestational age

Übergeordnetes Werk:	In: Journal of Rawalpindi Medical College - Rawalpindi Medical University, 2020, 21(2017), 3
Übergeordnetes Werk:	volume:21 ; year:2017 ; number:3

Links:	Link aufrufen Link aufrufen Journal toc Journal toc

Katalog-ID:	DOAJ022869891

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520			\|a Background: To compare efficacy of manual vacuum aspiration with sublingual misoprostol for the treatment of incomplete abortion in terms of frequency of blood loss and decreased haemoglobin. Methods: In this randomized controlled trial, patients with incomplete abortion, open cervical os, vaginal bleeding, history of vaginal bleeding during this pregnancy and uterine size of less than or equal to 12wks menstrual period were included. Consenting women were randomized to either Group A who received a single dose of 600 microgram of sublingual misoprostol or Group B who underwent manual vacuum aspiration for evacuation of retained products of conception. Both groups comprised of 150 patients each. Pre and post (after 48 hours) treatment haemoglobin levels were measured. Results: Mean fall in haemoglobin level <1g/dl from baseline level was seen in misoprostol group while a mean fall of <0.5g/dl from baseline level was observed in MVA group (p<0.001, 95% CI, t=1.64, eta squared=0.006). A significant association was found with haemoglobin level, parity and age, with p=0.001, p= 0.05, p=0.02 respectively Conclusion: The efficacy of manual vacuum aspiration (MVA) is indicated by lower level of blood loss (Hb<0.5g/dl from baseline) as compared to 600μg sublingual misoprostol. MVA is associated with less complications than misoprostol.
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allfields	(DE-627)DOAJ022869891 (DE-599)DOAJ1c4c8e11741c4ffe8fbc4dfbde7113b4 DE-627 ger DE-627 rakwb eng Saima Khurshid Ahmed verfasserin aut Comparison of Sublingual Misoprostol and Manual Vacuum Aspiration for the Treatment of Incomplete Abortion in First Trimester in Terms of Frequency of Decreased Haemoglobin Levels 2017 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background: To compare efficacy of manual vacuum aspiration with sublingual misoprostol for the treatment of incomplete abortion in terms of frequency of blood loss and decreased haemoglobin. Methods: In this randomized controlled trial, patients with incomplete abortion, open cervical os, vaginal bleeding, history of vaginal bleeding during this pregnancy and uterine size of less than or equal to 12wks menstrual period were included. Consenting women were randomized to either Group A who received a single dose of 600 microgram of sublingual misoprostol or Group B who underwent manual vacuum aspiration for evacuation of retained products of conception. Both groups comprised of 150 patients each. Pre and post (after 48 hours) treatment haemoglobin levels were measured. Results: Mean fall in haemoglobin level <1g/dl from baseline level was seen in misoprostol group while a mean fall of <0.5g/dl from baseline level was observed in MVA group (p<0.001, 95% CI, t=1.64, eta squared=0.006). A significant association was found with haemoglobin level, parity and age, with p=0.001, p= 0.05, p=0.02 respectively Conclusion: The efficacy of manual vacuum aspiration (MVA) is indicated by lower level of blood loss (Hb<0.5g/dl from baseline) as compared to 600μg sublingual misoprostol. MVA is associated with less complications than misoprostol. Manual vacuum aspiration Manual vacuum aspirationHaemoglobin level Gestational age Medicine R In Journal of Rawalpindi Medical College Rawalpindi Medical University, 2020 21(2017), 3 (DE-627)1735713449 16833570 nnns volume:21 year:2017 number:3 https://doaj.org/article/1c4c8e11741c4ffe8fbc4dfbde7113b4 kostenfrei https://www.journalrmc.com/index.php/JRMC/article/view/18 kostenfrei https://doaj.org/toc/1683-3562 Journal toc kostenfrei https://doaj.org/toc/1683-3570 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 21 2017 3
spelling	(DE-627)DOAJ022869891 (DE-599)DOAJ1c4c8e11741c4ffe8fbc4dfbde7113b4 DE-627 ger DE-627 rakwb eng Saima Khurshid Ahmed verfasserin aut Comparison of Sublingual Misoprostol and Manual Vacuum Aspiration for the Treatment of Incomplete Abortion in First Trimester in Terms of Frequency of Decreased Haemoglobin Levels 2017 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background: To compare efficacy of manual vacuum aspiration with sublingual misoprostol for the treatment of incomplete abortion in terms of frequency of blood loss and decreased haemoglobin. Methods: In this randomized controlled trial, patients with incomplete abortion, open cervical os, vaginal bleeding, history of vaginal bleeding during this pregnancy and uterine size of less than or equal to 12wks menstrual period were included. Consenting women were randomized to either Group A who received a single dose of 600 microgram of sublingual misoprostol or Group B who underwent manual vacuum aspiration for evacuation of retained products of conception. Both groups comprised of 150 patients each. Pre and post (after 48 hours) treatment haemoglobin levels were measured. Results: Mean fall in haemoglobin level <1g/dl from baseline level was seen in misoprostol group while a mean fall of <0.5g/dl from baseline level was observed in MVA group (p<0.001, 95% CI, t=1.64, eta squared=0.006). A significant association was found with haemoglobin level, parity and age, with p=0.001, p= 0.05, p=0.02 respectively Conclusion: The efficacy of manual vacuum aspiration (MVA) is indicated by lower level of blood loss (Hb<0.5g/dl from baseline) as compared to 600μg sublingual misoprostol. MVA is associated with less complications than misoprostol. Manual vacuum aspiration Manual vacuum aspirationHaemoglobin level Gestational age Medicine R In Journal of Rawalpindi Medical College Rawalpindi Medical University, 2020 21(2017), 3 (DE-627)1735713449 16833570 nnns volume:21 year:2017 number:3 https://doaj.org/article/1c4c8e11741c4ffe8fbc4dfbde7113b4 kostenfrei https://www.journalrmc.com/index.php/JRMC/article/view/18 kostenfrei https://doaj.org/toc/1683-3562 Journal toc kostenfrei https://doaj.org/toc/1683-3570 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 21 2017 3
allfields_unstemmed	(DE-627)DOAJ022869891 (DE-599)DOAJ1c4c8e11741c4ffe8fbc4dfbde7113b4 DE-627 ger DE-627 rakwb eng Saima Khurshid Ahmed verfasserin aut Comparison of Sublingual Misoprostol and Manual Vacuum Aspiration for the Treatment of Incomplete Abortion in First Trimester in Terms of Frequency of Decreased Haemoglobin Levels 2017 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background: To compare efficacy of manual vacuum aspiration with sublingual misoprostol for the treatment of incomplete abortion in terms of frequency of blood loss and decreased haemoglobin. Methods: In this randomized controlled trial, patients with incomplete abortion, open cervical os, vaginal bleeding, history of vaginal bleeding during this pregnancy and uterine size of less than or equal to 12wks menstrual period were included. Consenting women were randomized to either Group A who received a single dose of 600 microgram of sublingual misoprostol or Group B who underwent manual vacuum aspiration for evacuation of retained products of conception. Both groups comprised of 150 patients each. Pre and post (after 48 hours) treatment haemoglobin levels were measured. Results: Mean fall in haemoglobin level <1g/dl from baseline level was seen in misoprostol group while a mean fall of <0.5g/dl from baseline level was observed in MVA group (p<0.001, 95% CI, t=1.64, eta squared=0.006). A significant association was found with haemoglobin level, parity and age, with p=0.001, p= 0.05, p=0.02 respectively Conclusion: The efficacy of manual vacuum aspiration (MVA) is indicated by lower level of blood loss (Hb<0.5g/dl from baseline) as compared to 600μg sublingual misoprostol. MVA is associated with less complications than misoprostol. Manual vacuum aspiration Manual vacuum aspirationHaemoglobin level Gestational age Medicine R In Journal of Rawalpindi Medical College Rawalpindi Medical University, 2020 21(2017), 3 (DE-627)1735713449 16833570 nnns volume:21 year:2017 number:3 https://doaj.org/article/1c4c8e11741c4ffe8fbc4dfbde7113b4 kostenfrei https://www.journalrmc.com/index.php/JRMC/article/view/18 kostenfrei https://doaj.org/toc/1683-3562 Journal toc kostenfrei https://doaj.org/toc/1683-3570 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 21 2017 3
allfieldsGer	(DE-627)DOAJ022869891 (DE-599)DOAJ1c4c8e11741c4ffe8fbc4dfbde7113b4 DE-627 ger DE-627 rakwb eng Saima Khurshid Ahmed verfasserin aut Comparison of Sublingual Misoprostol and Manual Vacuum Aspiration for the Treatment of Incomplete Abortion in First Trimester in Terms of Frequency of Decreased Haemoglobin Levels 2017 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background: To compare efficacy of manual vacuum aspiration with sublingual misoprostol for the treatment of incomplete abortion in terms of frequency of blood loss and decreased haemoglobin. Methods: In this randomized controlled trial, patients with incomplete abortion, open cervical os, vaginal bleeding, history of vaginal bleeding during this pregnancy and uterine size of less than or equal to 12wks menstrual period were included. Consenting women were randomized to either Group A who received a single dose of 600 microgram of sublingual misoprostol or Group B who underwent manual vacuum aspiration for evacuation of retained products of conception. Both groups comprised of 150 patients each. Pre and post (after 48 hours) treatment haemoglobin levels were measured. Results: Mean fall in haemoglobin level <1g/dl from baseline level was seen in misoprostol group while a mean fall of <0.5g/dl from baseline level was observed in MVA group (p<0.001, 95% CI, t=1.64, eta squared=0.006). A significant association was found with haemoglobin level, parity and age, with p=0.001, p= 0.05, p=0.02 respectively Conclusion: The efficacy of manual vacuum aspiration (MVA) is indicated by lower level of blood loss (Hb<0.5g/dl from baseline) as compared to 600μg sublingual misoprostol. MVA is associated with less complications than misoprostol. Manual vacuum aspiration Manual vacuum aspirationHaemoglobin level Gestational age Medicine R In Journal of Rawalpindi Medical College Rawalpindi Medical University, 2020 21(2017), 3 (DE-627)1735713449 16833570 nnns volume:21 year:2017 number:3 https://doaj.org/article/1c4c8e11741c4ffe8fbc4dfbde7113b4 kostenfrei https://www.journalrmc.com/index.php/JRMC/article/view/18 kostenfrei https://doaj.org/toc/1683-3562 Journal toc kostenfrei https://doaj.org/toc/1683-3570 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 21 2017 3
allfieldsSound	(DE-627)DOAJ022869891 (DE-599)DOAJ1c4c8e11741c4ffe8fbc4dfbde7113b4 DE-627 ger DE-627 rakwb eng Saima Khurshid Ahmed verfasserin aut Comparison of Sublingual Misoprostol and Manual Vacuum Aspiration for the Treatment of Incomplete Abortion in First Trimester in Terms of Frequency of Decreased Haemoglobin Levels 2017 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background: To compare efficacy of manual vacuum aspiration with sublingual misoprostol for the treatment of incomplete abortion in terms of frequency of blood loss and decreased haemoglobin. Methods: In this randomized controlled trial, patients with incomplete abortion, open cervical os, vaginal bleeding, history of vaginal bleeding during this pregnancy and uterine size of less than or equal to 12wks menstrual period were included. Consenting women were randomized to either Group A who received a single dose of 600 microgram of sublingual misoprostol or Group B who underwent manual vacuum aspiration for evacuation of retained products of conception. Both groups comprised of 150 patients each. Pre and post (after 48 hours) treatment haemoglobin levels were measured. Results: Mean fall in haemoglobin level <1g/dl from baseline level was seen in misoprostol group while a mean fall of <0.5g/dl from baseline level was observed in MVA group (p<0.001, 95% CI, t=1.64, eta squared=0.006). A significant association was found with haemoglobin level, parity and age, with p=0.001, p= 0.05, p=0.02 respectively Conclusion: The efficacy of manual vacuum aspiration (MVA) is indicated by lower level of blood loss (Hb<0.5g/dl from baseline) as compared to 600μg sublingual misoprostol. MVA is associated with less complications than misoprostol. Manual vacuum aspiration Manual vacuum aspirationHaemoglobin level Gestational age Medicine R In Journal of Rawalpindi Medical College Rawalpindi Medical University, 2020 21(2017), 3 (DE-627)1735713449 16833570 nnns volume:21 year:2017 number:3 https://doaj.org/article/1c4c8e11741c4ffe8fbc4dfbde7113b4 kostenfrei https://www.journalrmc.com/index.php/JRMC/article/view/18 kostenfrei https://doaj.org/toc/1683-3562 Journal toc kostenfrei https://doaj.org/toc/1683-3570 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 21 2017 3
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Methods: In this randomized controlled trial, patients with incomplete abortion, open cervical os, vaginal bleeding, history of vaginal bleeding during this pregnancy and uterine size of less than or equal to 12wks menstrual period were included. Consenting women were randomized to either Group A who received a single dose of 600 microgram of sublingual misoprostol or Group B who underwent manual vacuum aspiration for evacuation of retained products of conception. Both groups comprised of 150 patients each. Pre and post (after 48 hours) treatment haemoglobin levels were measured. Results: Mean fall in haemoglobin level <1g/dl from baseline level was seen in misoprostol group while a mean fall of <0.5g/dl from baseline level was observed in MVA group (p<0.001, 95% CI, t=1.64, eta squared=0.006). A significant association was found with haemoglobin level, parity and age, with p=0.001, p= 0.05, p=0.02 respectively Conclusion: The efficacy of manual vacuum aspiration (MVA) is indicated by lower level of blood loss (Hb<0.5g/dl from baseline) as compared to 600μg sublingual misoprostol. 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author	Saima Khurshid Ahmed
spellingShingle	Saima Khurshid Ahmed misc Manual vacuum aspiration misc Manual vacuum aspirationHaemoglobin level misc Gestational age misc Medicine misc R Comparison of Sublingual Misoprostol and Manual Vacuum Aspiration for the Treatment of Incomplete Abortion in First Trimester in Terms of Frequency of Decreased Haemoglobin Levels
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topic_title	Comparison of Sublingual Misoprostol and Manual Vacuum Aspiration for the Treatment of Incomplete Abortion in First Trimester in Terms of Frequency of Decreased Haemoglobin Levels Manual vacuum aspiration Manual vacuum aspirationHaemoglobin level Gestational age
topic	misc Manual vacuum aspiration misc Manual vacuum aspirationHaemoglobin level misc Gestational age misc Medicine misc R
topic_unstemmed	misc Manual vacuum aspiration misc Manual vacuum aspirationHaemoglobin level misc Gestational age misc Medicine misc R
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title	Comparison of Sublingual Misoprostol and Manual Vacuum Aspiration for the Treatment of Incomplete Abortion in First Trimester in Terms of Frequency of Decreased Haemoglobin Levels
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title_full	Comparison of Sublingual Misoprostol and Manual Vacuum Aspiration for the Treatment of Incomplete Abortion in First Trimester in Terms of Frequency of Decreased Haemoglobin Levels
author_sort	Saima Khurshid Ahmed
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title_sort	comparison of sublingual misoprostol and manual vacuum aspiration for the treatment of incomplete abortion in first trimester in terms of frequency of decreased haemoglobin levels
title_auth	Comparison of Sublingual Misoprostol and Manual Vacuum Aspiration for the Treatment of Incomplete Abortion in First Trimester in Terms of Frequency of Decreased Haemoglobin Levels
abstract	Background: To compare efficacy of manual vacuum aspiration with sublingual misoprostol for the treatment of incomplete abortion in terms of frequency of blood loss and decreased haemoglobin. Methods: In this randomized controlled trial, patients with incomplete abortion, open cervical os, vaginal bleeding, history of vaginal bleeding during this pregnancy and uterine size of less than or equal to 12wks menstrual period were included. Consenting women were randomized to either Group A who received a single dose of 600 microgram of sublingual misoprostol or Group B who underwent manual vacuum aspiration for evacuation of retained products of conception. Both groups comprised of 150 patients each. Pre and post (after 48 hours) treatment haemoglobin levels were measured. Results: Mean fall in haemoglobin level <1g/dl from baseline level was seen in misoprostol group while a mean fall of <0.5g/dl from baseline level was observed in MVA group (p<0.001, 95% CI, t=1.64, eta squared=0.006). A significant association was found with haemoglobin level, parity and age, with p=0.001, p= 0.05, p=0.02 respectively Conclusion: The efficacy of manual vacuum aspiration (MVA) is indicated by lower level of blood loss (Hb<0.5g/dl from baseline) as compared to 600μg sublingual misoprostol. MVA is associated with less complications than misoprostol.
abstractGer	Background: To compare efficacy of manual vacuum aspiration with sublingual misoprostol for the treatment of incomplete abortion in terms of frequency of blood loss and decreased haemoglobin. Methods: In this randomized controlled trial, patients with incomplete abortion, open cervical os, vaginal bleeding, history of vaginal bleeding during this pregnancy and uterine size of less than or equal to 12wks menstrual period were included. Consenting women were randomized to either Group A who received a single dose of 600 microgram of sublingual misoprostol or Group B who underwent manual vacuum aspiration for evacuation of retained products of conception. Both groups comprised of 150 patients each. Pre and post (after 48 hours) treatment haemoglobin levels were measured. Results: Mean fall in haemoglobin level <1g/dl from baseline level was seen in misoprostol group while a mean fall of <0.5g/dl from baseline level was observed in MVA group (p<0.001, 95% CI, t=1.64, eta squared=0.006). A significant association was found with haemoglobin level, parity and age, with p=0.001, p= 0.05, p=0.02 respectively Conclusion: The efficacy of manual vacuum aspiration (MVA) is indicated by lower level of blood loss (Hb<0.5g/dl from baseline) as compared to 600μg sublingual misoprostol. MVA is associated with less complications than misoprostol.
abstract_unstemmed	Background: To compare efficacy of manual vacuum aspiration with sublingual misoprostol for the treatment of incomplete abortion in terms of frequency of blood loss and decreased haemoglobin. Methods: In this randomized controlled trial, patients with incomplete abortion, open cervical os, vaginal bleeding, history of vaginal bleeding during this pregnancy and uterine size of less than or equal to 12wks menstrual period were included. Consenting women were randomized to either Group A who received a single dose of 600 microgram of sublingual misoprostol or Group B who underwent manual vacuum aspiration for evacuation of retained products of conception. Both groups comprised of 150 patients each. Pre and post (after 48 hours) treatment haemoglobin levels were measured. Results: Mean fall in haemoglobin level <1g/dl from baseline level was seen in misoprostol group while a mean fall of <0.5g/dl from baseline level was observed in MVA group (p<0.001, 95% CI, t=1.64, eta squared=0.006). A significant association was found with haemoglobin level, parity and age, with p=0.001, p= 0.05, p=0.02 respectively Conclusion: The efficacy of manual vacuum aspiration (MVA) is indicated by lower level of blood loss (Hb<0.5g/dl from baseline) as compared to 600μg sublingual misoprostol. MVA is associated with less complications than misoprostol.
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title_short	Comparison of Sublingual Misoprostol and Manual Vacuum Aspiration for the Treatment of Incomplete Abortion in First Trimester in Terms of Frequency of Decreased Haemoglobin Levels
url	https://doaj.org/article/1c4c8e11741c4ffe8fbc4dfbde7113b4 https://www.journalrmc.com/index.php/JRMC/article/view/18 https://doaj.org/toc/1683-3562 https://doaj.org/toc/1683-3570
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Comparison of Sublingual Misoprostol and Manual Vacuum Aspiration for the Treatment of Incomplete Abortion in First Trimester in Terms of Frequency of Decreased Haemoglobin Levels

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