Phytochemical and Pharmacological Research in <i<Agrimonia eupatoria</i< L. Herb Extract with Anti-Inflammatory and Hepatoprotective Properties

The most promising plant from the genus Agrimony (<i<Agrimonia</i< L.) of the <i<Rosaceae</i< family for use in medical practice is <i<Agrimonia eupatoria</i< L. Phytochemical and pharmacological research in <i<Agrimonia eupatoria</i< L. herb extract,...
Ausführliche Beschreibung

Gespeichert in:

Autor*in:	Natalia Huzio [verfasserIn] Andriy Grytsyk [verfasserIn] Ain Raal [verfasserIn] Lyubov Grytsyk [verfasserIn] Oleh Koshovyi [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2022

Schlagwörter:	herb extract biological active substances hepatoprotective activity

Übergeordnetes Werk:	In: Plants - MDPI AG, 2013, 11(2022), 18, p 2371
Übergeordnetes Werk:	volume:11 ; year:2022 ; number:18, p 2371

Links:	Link aufrufen Link aufrufen Link aufrufen Journal toc

DOI / URN:	10.3390/plants11182371

Katalog-ID:	DOAJ023304839

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520			\|a The most promising plant from the genus Agrimony (<i<Agrimonia</i< L.) of the <i<Rosaceae</i< family for use in medical practice is <i<Agrimonia eupatoria</i< L. Phytochemical and pharmacological research in <i<Agrimonia eupatoria</i< L. herb extract, obtained with using 40% ethanol solution as an extractant were carried out. A total of 11 free and 17 bound monosaccharides, 17 amino acids were found in the studied extract, 9 of which are essential. Gallic and ellagic acids, gallocatechin, epigallocatechin, catechin, epicatechin, and epicatechin gallate were identified in the extract of <i<A. eupatoria</i< by the HPLC method; as well as hydroxycinnamic acids: hydroxyphenylacetate, caffeic, syringic, p-coumaric, ferulic, sinapic, cinnamic and quinic acid; flavonoids: quercetin-3-D-glucoside (isoquercitrin), neohesperidin, naringenin, luteolin were found, and their quantitative content was determined, as well by spectrophotometric methods. The herb extract of <i<A. eupatoria</i< belongs to practically non-toxic substances and has pronounced anti-inflammatory (at a dose of 10.0 mg/kg anti-exudative activity reached a maximum in 5 h (88.17%)) and hepatoprotective activity (at a dose of 25 mg/kg it reduce AlAt level by 1.1 and 1.2 times, respectively; AsAt by 1.2 and 1.1 times, respectively), reduces the level of lipid peroxidation and stabilizes the membrane structures of liver cells. Thus, the herb extract of <i<A. eupatoria</i< is a promising substance for the creation of phytomedicines with anti-inflammatory and hepatoprotective activity.
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spelling	10.3390/plants11182371 doi (DE-627)DOAJ023304839 (DE-599)DOAJe9c24f7150e14ab49113621a1bd49998 DE-627 ger DE-627 rakwb eng QK1-989 Natalia Huzio verfasserin aut Phytochemical and Pharmacological Research in <i<Agrimonia eupatoria</i< L. Herb Extract with Anti-Inflammatory and Hepatoprotective Properties 2022 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier The most promising plant from the genus Agrimony (<i<Agrimonia</i< L.) of the <i<Rosaceae</i< family for use in medical practice is <i<Agrimonia eupatoria</i< L. Phytochemical and pharmacological research in <i<Agrimonia eupatoria</i< L. herb extract, obtained with using 40% ethanol solution as an extractant were carried out. A total of 11 free and 17 bound monosaccharides, 17 amino acids were found in the studied extract, 9 of which are essential. Gallic and ellagic acids, gallocatechin, epigallocatechin, catechin, epicatechin, and epicatechin gallate were identified in the extract of <i<A. eupatoria</i< by the HPLC method; as well as hydroxycinnamic acids: hydroxyphenylacetate, caffeic, syringic, p-coumaric, ferulic, sinapic, cinnamic and quinic acid; flavonoids: quercetin-3-D-glucoside (isoquercitrin), neohesperidin, naringenin, luteolin were found, and their quantitative content was determined, as well by spectrophotometric methods. The herb extract of <i<A. eupatoria</i< belongs to practically non-toxic substances and has pronounced anti-inflammatory (at a dose of 10.0 mg/kg anti-exudative activity reached a maximum in 5 h (88.17%)) and hepatoprotective activity (at a dose of 25 mg/kg it reduce AlAt level by 1.1 and 1.2 times, respectively; AsAt by 1.2 and 1.1 times, respectively), reduces the level of lipid peroxidation and stabilizes the membrane structures of liver cells. Thus, the herb extract of <i<A. eupatoria</i< is a promising substance for the creation of phytomedicines with anti-inflammatory and hepatoprotective activity. <i<Agrimonia eupatoria</i< L. herb extract biological active substances hepatoprotective activity Botany Andriy Grytsyk verfasserin aut Ain Raal verfasserin aut Lyubov Grytsyk verfasserin aut Oleh Koshovyi verfasserin aut In Plants MDPI AG, 2013 11(2022), 18, p 2371 (DE-627)737288345 (DE-600)2704341-1 22237747 nnns volume:11 year:2022 number:18, p 2371 https://doi.org/10.3390/plants11182371 kostenfrei https://doaj.org/article/e9c24f7150e14ab49113621a1bd49998 kostenfrei https://www.mdpi.com/2223-7747/11/18/2371 kostenfrei https://doaj.org/toc/2223-7747 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 11 2022 18, p 2371
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callnumber-first	Q - Science
author	Natalia Huzio
spellingShingle	Natalia Huzio misc QK1-989 misc <i<Agrimonia eupatoria</i< L. misc herb misc extract misc biological active substances misc hepatoprotective activity misc Botany Phytochemical and Pharmacological Research in <i<Agrimonia eupatoria</i< L. Herb Extract with Anti-Inflammatory and Hepatoprotective Properties
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topic_title	QK1-989 Phytochemical and Pharmacological Research in <i<Agrimonia eupatoria</i< L. Herb Extract with Anti-Inflammatory and Hepatoprotective Properties <i<Agrimonia eupatoria</i< L. herb extract biological active substances hepatoprotective activity
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title	Phytochemical and Pharmacological Research in <i<Agrimonia eupatoria</i< L. Herb Extract with Anti-Inflammatory and Hepatoprotective Properties
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title_full	Phytochemical and Pharmacological Research in <i<Agrimonia eupatoria</i< L. Herb Extract with Anti-Inflammatory and Hepatoprotective Properties
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title_sort	phytochemical and pharmacological research in <i<agrimonia eupatoria</i< l. herb extract with anti-inflammatory and hepatoprotective properties
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title_auth	Phytochemical and Pharmacological Research in <i<Agrimonia eupatoria</i< L. Herb Extract with Anti-Inflammatory and Hepatoprotective Properties
abstract	The most promising plant from the genus Agrimony (<i<Agrimonia</i< L.) of the <i<Rosaceae</i< family for use in medical practice is <i<Agrimonia eupatoria</i< L. Phytochemical and pharmacological research in <i<Agrimonia eupatoria</i< L. herb extract, obtained with using 40% ethanol solution as an extractant were carried out. A total of 11 free and 17 bound monosaccharides, 17 amino acids were found in the studied extract, 9 of which are essential. Gallic and ellagic acids, gallocatechin, epigallocatechin, catechin, epicatechin, and epicatechin gallate were identified in the extract of <i<A. eupatoria</i< by the HPLC method; as well as hydroxycinnamic acids: hydroxyphenylacetate, caffeic, syringic, p-coumaric, ferulic, sinapic, cinnamic and quinic acid; flavonoids: quercetin-3-D-glucoside (isoquercitrin), neohesperidin, naringenin, luteolin were found, and their quantitative content was determined, as well by spectrophotometric methods. The herb extract of <i<A. eupatoria</i< belongs to practically non-toxic substances and has pronounced anti-inflammatory (at a dose of 10.0 mg/kg anti-exudative activity reached a maximum in 5 h (88.17%)) and hepatoprotective activity (at a dose of 25 mg/kg it reduce AlAt level by 1.1 and 1.2 times, respectively; AsAt by 1.2 and 1.1 times, respectively), reduces the level of lipid peroxidation and stabilizes the membrane structures of liver cells. Thus, the herb extract of <i<A. eupatoria</i< is a promising substance for the creation of phytomedicines with anti-inflammatory and hepatoprotective activity.
abstractGer	The most promising plant from the genus Agrimony (<i<Agrimonia</i< L.) of the <i<Rosaceae</i< family for use in medical practice is <i<Agrimonia eupatoria</i< L. Phytochemical and pharmacological research in <i<Agrimonia eupatoria</i< L. herb extract, obtained with using 40% ethanol solution as an extractant were carried out. A total of 11 free and 17 bound monosaccharides, 17 amino acids were found in the studied extract, 9 of which are essential. Gallic and ellagic acids, gallocatechin, epigallocatechin, catechin, epicatechin, and epicatechin gallate were identified in the extract of <i<A. eupatoria</i< by the HPLC method; as well as hydroxycinnamic acids: hydroxyphenylacetate, caffeic, syringic, p-coumaric, ferulic, sinapic, cinnamic and quinic acid; flavonoids: quercetin-3-D-glucoside (isoquercitrin), neohesperidin, naringenin, luteolin were found, and their quantitative content was determined, as well by spectrophotometric methods. The herb extract of <i<A. eupatoria</i< belongs to practically non-toxic substances and has pronounced anti-inflammatory (at a dose of 10.0 mg/kg anti-exudative activity reached a maximum in 5 h (88.17%)) and hepatoprotective activity (at a dose of 25 mg/kg it reduce AlAt level by 1.1 and 1.2 times, respectively; AsAt by 1.2 and 1.1 times, respectively), reduces the level of lipid peroxidation and stabilizes the membrane structures of liver cells. Thus, the herb extract of <i<A. eupatoria</i< is a promising substance for the creation of phytomedicines with anti-inflammatory and hepatoprotective activity.
abstract_unstemmed	The most promising plant from the genus Agrimony (<i<Agrimonia</i< L.) of the <i<Rosaceae</i< family for use in medical practice is <i<Agrimonia eupatoria</i< L. Phytochemical and pharmacological research in <i<Agrimonia eupatoria</i< L. herb extract, obtained with using 40% ethanol solution as an extractant were carried out. A total of 11 free and 17 bound monosaccharides, 17 amino acids were found in the studied extract, 9 of which are essential. Gallic and ellagic acids, gallocatechin, epigallocatechin, catechin, epicatechin, and epicatechin gallate were identified in the extract of <i<A. eupatoria</i< by the HPLC method; as well as hydroxycinnamic acids: hydroxyphenylacetate, caffeic, syringic, p-coumaric, ferulic, sinapic, cinnamic and quinic acid; flavonoids: quercetin-3-D-glucoside (isoquercitrin), neohesperidin, naringenin, luteolin were found, and their quantitative content was determined, as well by spectrophotometric methods. The herb extract of <i<A. eupatoria</i< belongs to practically non-toxic substances and has pronounced anti-inflammatory (at a dose of 10.0 mg/kg anti-exudative activity reached a maximum in 5 h (88.17%)) and hepatoprotective activity (at a dose of 25 mg/kg it reduce AlAt level by 1.1 and 1.2 times, respectively; AsAt by 1.2 and 1.1 times, respectively), reduces the level of lipid peroxidation and stabilizes the membrane structures of liver cells. Thus, the herb extract of <i<A. eupatoria</i< is a promising substance for the creation of phytomedicines with anti-inflammatory and hepatoprotective activity.
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title_short	Phytochemical and Pharmacological Research in <i<Agrimonia eupatoria</i< L. Herb Extract with Anti-Inflammatory and Hepatoprotective Properties
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The herb extract of <i<A. eupatoria</i< belongs to practically non-toxic substances and has pronounced anti-inflammatory (at a dose of 10.0 mg/kg anti-exudative activity reached a maximum in 5 h (88.17%)) and hepatoprotective activity (at a dose of 25 mg/kg it reduce AlAt level by 1.1 and 1.2 times, respectively; AsAt by 1.2 and 1.1 times, respectively), reduces the level of lipid peroxidation and stabilizes the membrane structures of liver cells. 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Phytochemical and Pharmacological Research in <i<Agrimonia eupatoria</i< L. Herb Extract with Anti-Inflammatory and Hepatoprotective Properties

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