Molecular Approaches for Diagnosis, Therapy and Prevention of Cow’s Milk Allergy

Cow’s milk is one of the most important and basic nutrients introduced early in life in our diet but can induce IgE-associated allergy. IgE-associated allergy to cow’s milk can cause severe allergic manifestations in the gut, skin and even in the respiratory tract and may lead to life-threatening an...
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Autor*in:	Birgit Linhart [verfasserIn] Raphaela Freidl [verfasserIn] Olga Elisyutina [verfasserIn] Musa Khaitov [verfasserIn] Alexander Karaulov [verfasserIn] Rudolf Valenta [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2019

Schlagwörter:	cow’s milk allergy cow’s milk allergens diagnosis of cow’s milk allergy molecular diagnosis treatment of cow’s milk allergy prevention of cow’s milk allergy

Übergeordnetes Werk:	In: Nutrients - MDPI AG, 2009, 11(2019), 7, p 1492
Übergeordnetes Werk:	volume:11 ; year:2019 ; number:7, p 1492

Links:	Link aufrufen Link aufrufen Link aufrufen Journal toc

DOI / URN:	10.3390/nu11071492

Katalog-ID:	DOAJ023322217

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520			\|a Cow’s milk is one of the most important and basic nutrients introduced early in life in our diet but can induce IgE-associated allergy. IgE-associated allergy to cow’s milk can cause severe allergic manifestations in the gut, skin and even in the respiratory tract and may lead to life-threatening anaphylactic shock due to the stability of certain cow’s milk allergens. Here, we provide an overview about the allergen molecules in cow’s milk and the advantages of the molecular diagnosis of IgE sensitization to cow’s milk by serology. In addition, we review current strategies for prevention and treatment of cow’s milk allergy and discuss how they could be improved in the future by innovative molecular approaches that are based on defined recombinant allergens, recombinant hypoallergenic allergen derivatives and synthetic peptides.
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allfieldsSound	10.3390/nu11071492 doi (DE-627)DOAJ023322217 (DE-599)DOAJ4ce17e089e414c55bff63fabae4b3865 DE-627 ger DE-627 rakwb eng TX341-641 Birgit Linhart verfasserin aut Molecular Approaches for Diagnosis, Therapy and Prevention of Cow’s Milk Allergy 2019 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Cow’s milk is one of the most important and basic nutrients introduced early in life in our diet but can induce IgE-associated allergy. IgE-associated allergy to cow’s milk can cause severe allergic manifestations in the gut, skin and even in the respiratory tract and may lead to life-threatening anaphylactic shock due to the stability of certain cow’s milk allergens. Here, we provide an overview about the allergen molecules in cow’s milk and the advantages of the molecular diagnosis of IgE sensitization to cow’s milk by serology. In addition, we review current strategies for prevention and treatment of cow’s milk allergy and discuss how they could be improved in the future by innovative molecular approaches that are based on defined recombinant allergens, recombinant hypoallergenic allergen derivatives and synthetic peptides. cow’s milk allergy cow’s milk allergens diagnosis of cow’s milk allergy molecular diagnosis treatment of cow’s milk allergy prevention of cow’s milk allergy Nutrition. Foods and food supply Raphaela Freidl verfasserin aut Olga Elisyutina verfasserin aut Musa Khaitov verfasserin aut Alexander Karaulov verfasserin aut Rudolf Valenta verfasserin aut In Nutrients MDPI AG, 2009 11(2019), 7, p 1492 (DE-627)610604155 (DE-600)2518386-2 20726643 nnns volume:11 year:2019 number:7, p 1492 https://doi.org/10.3390/nu11071492 kostenfrei https://doaj.org/article/4ce17e089e414c55bff63fabae4b3865 kostenfrei https://www.mdpi.com/2072-6643/11/7/1492 kostenfrei https://doaj.org/toc/2072-6643 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 11 2019 7, p 1492
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author	Birgit Linhart
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topic_title	TX341-641 Molecular Approaches for Diagnosis, Therapy and Prevention of Cow’s Milk Allergy cow’s milk allergy cow’s milk allergens diagnosis of cow’s milk allergy molecular diagnosis treatment of cow’s milk allergy prevention of cow’s milk allergy
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title	Molecular Approaches for Diagnosis, Therapy and Prevention of Cow’s Milk Allergy
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title_sort	molecular approaches for diagnosis, therapy and prevention of cow’s milk allergy
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title_auth	Molecular Approaches for Diagnosis, Therapy and Prevention of Cow’s Milk Allergy
abstract	Cow’s milk is one of the most important and basic nutrients introduced early in life in our diet but can induce IgE-associated allergy. IgE-associated allergy to cow’s milk can cause severe allergic manifestations in the gut, skin and even in the respiratory tract and may lead to life-threatening anaphylactic shock due to the stability of certain cow’s milk allergens. Here, we provide an overview about the allergen molecules in cow’s milk and the advantages of the molecular diagnosis of IgE sensitization to cow’s milk by serology. In addition, we review current strategies for prevention and treatment of cow’s milk allergy and discuss how they could be improved in the future by innovative molecular approaches that are based on defined recombinant allergens, recombinant hypoallergenic allergen derivatives and synthetic peptides.
abstractGer	Cow’s milk is one of the most important and basic nutrients introduced early in life in our diet but can induce IgE-associated allergy. IgE-associated allergy to cow’s milk can cause severe allergic manifestations in the gut, skin and even in the respiratory tract and may lead to life-threatening anaphylactic shock due to the stability of certain cow’s milk allergens. Here, we provide an overview about the allergen molecules in cow’s milk and the advantages of the molecular diagnosis of IgE sensitization to cow’s milk by serology. In addition, we review current strategies for prevention and treatment of cow’s milk allergy and discuss how they could be improved in the future by innovative molecular approaches that are based on defined recombinant allergens, recombinant hypoallergenic allergen derivatives and synthetic peptides.
abstract_unstemmed	Cow’s milk is one of the most important and basic nutrients introduced early in life in our diet but can induce IgE-associated allergy. IgE-associated allergy to cow’s milk can cause severe allergic manifestations in the gut, skin and even in the respiratory tract and may lead to life-threatening anaphylactic shock due to the stability of certain cow’s milk allergens. Here, we provide an overview about the allergen molecules in cow’s milk and the advantages of the molecular diagnosis of IgE sensitization to cow’s milk by serology. In addition, we review current strategies for prevention and treatment of cow’s milk allergy and discuss how they could be improved in the future by innovative molecular approaches that are based on defined recombinant allergens, recombinant hypoallergenic allergen derivatives and synthetic peptides.
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title_short	Molecular Approaches for Diagnosis, Therapy and Prevention of Cow’s Milk Allergy
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