Nipah virus: Biology, disease, treatment, control, and prevention

Nipah virus (NiV), an RNA virus, belongs to genus Henipahvirus of family Paramyxoviridiae. First isolated and identified in Malaysia in 1999, NiV affects humans as well as animals such as pigs, cattle, cats, dogs, ponies etc. Fruit bats of genus Pteropus serve as reservoir host for NiV. Bangladesh h...
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Autor*in:	Rahul Narang [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2018

Schlagwörter:	Biology disease Nipah virus prevention and control treatment

Übergeordnetes Werk:	In: Journal of Mahatma Gandhi Institute of Medical Sciences - Wolters Kluwer Medknow Publications, 2018, 23(2018), 2, Seite 65-68
Übergeordnetes Werk:	volume:23 ; year:2018 ; number:2 ; pages:65-68

Links:	Link aufrufen Link aufrufen Link aufrufen Journal toc

DOI / URN:	10.4103/jmgims.jmgims_39_18

Katalog-ID:	DOAJ023925604

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520			\|a Nipah virus (NiV), an RNA virus, belongs to genus Henipahvirus of family Paramyxoviridiae. First isolated and identified in Malaysia in 1999, NiV affects humans as well as animals such as pigs, cattle, cats, dogs, ponies etc. Fruit bats of genus Pteropus serve as reservoir host for NiV. Bangladesh has experienced almost annual outbreaks while there have been few outbreaks in India, the latest was in Kerala state in 2018. NiV has become an important human pathogen causing acute encephalitis syndrome associated with high mortality. Central nervous and respiratory systems are involved mainly along with multi-organ vasculitis and infection of endothelial cells. In early stages of disease, laboratory diagnosis can be made by isolation as well as real time polymerase chain reaction (RT-PCR) from throat swabs, nasal swabs, cerebrospinal fluid, urine and blood. In later stages, serological tests for antibody detection using ELISA are useful. Immuno-histochemistry on tissues collected after autopsy can also be performed. There is no specific treatment available for this infection and supportive therapy along with barrier nursing is mode of treatment. Monoclonal antibodies and vaccines against NiV have been found effective in animals but are yet to be tested in humans. The infection can be prevented in endemic areas by reducing exposure to fruit bats, pigs and date palm sap.
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spelling	10.4103/jmgims.jmgims_39_18 doi (DE-627)DOAJ023925604 (DE-599)DOAJ47896a9734ff4fcbac3989c028e4088e DE-627 ger DE-627 rakwb eng RZ201-999 Rahul Narang verfasserin aut Nipah virus: Biology, disease, treatment, control, and prevention 2018 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Nipah virus (NiV), an RNA virus, belongs to genus Henipahvirus of family Paramyxoviridiae. First isolated and identified in Malaysia in 1999, NiV affects humans as well as animals such as pigs, cattle, cats, dogs, ponies etc. Fruit bats of genus Pteropus serve as reservoir host for NiV. Bangladesh has experienced almost annual outbreaks while there have been few outbreaks in India, the latest was in Kerala state in 2018. NiV has become an important human pathogen causing acute encephalitis syndrome associated with high mortality. Central nervous and respiratory systems are involved mainly along with multi-organ vasculitis and infection of endothelial cells. In early stages of disease, laboratory diagnosis can be made by isolation as well as real time polymerase chain reaction (RT-PCR) from throat swabs, nasal swabs, cerebrospinal fluid, urine and blood. In later stages, serological tests for antibody detection using ELISA are useful. Immuno-histochemistry on tissues collected after autopsy can also be performed. There is no specific treatment available for this infection and supportive therapy along with barrier nursing is mode of treatment. Monoclonal antibodies and vaccines against NiV have been found effective in animals but are yet to be tested in humans. The infection can be prevented in endemic areas by reducing exposure to fruit bats, pigs and date palm sap. Biology disease Nipah virus prevention and control treatment Medicine R Other systems of medicine In Journal of Mahatma Gandhi Institute of Medical Sciences Wolters Kluwer Medknow Publications, 2018 23(2018), 2, Seite 65-68 (DE-627)77127498X (DE-600)2738506-1 23471948 nnns volume:23 year:2018 number:2 pages:65-68 https://doi.org/10.4103/jmgims.jmgims_39_18 kostenfrei https://doaj.org/article/47896a9734ff4fcbac3989c028e4088e kostenfrei http://www.jmgims.co.in/article.asp?issn=0971-9903;year=2018;volume=23;issue=2;spage=65;epage=68;aulast=Narang kostenfrei https://doaj.org/toc/0971-9903 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 23 2018 2 65-68
allfields_unstemmed	10.4103/jmgims.jmgims_39_18 doi (DE-627)DOAJ023925604 (DE-599)DOAJ47896a9734ff4fcbac3989c028e4088e DE-627 ger DE-627 rakwb eng RZ201-999 Rahul Narang verfasserin aut Nipah virus: Biology, disease, treatment, control, and prevention 2018 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Nipah virus (NiV), an RNA virus, belongs to genus Henipahvirus of family Paramyxoviridiae. First isolated and identified in Malaysia in 1999, NiV affects humans as well as animals such as pigs, cattle, cats, dogs, ponies etc. Fruit bats of genus Pteropus serve as reservoir host for NiV. Bangladesh has experienced almost annual outbreaks while there have been few outbreaks in India, the latest was in Kerala state in 2018. NiV has become an important human pathogen causing acute encephalitis syndrome associated with high mortality. Central nervous and respiratory systems are involved mainly along with multi-organ vasculitis and infection of endothelial cells. In early stages of disease, laboratory diagnosis can be made by isolation as well as real time polymerase chain reaction (RT-PCR) from throat swabs, nasal swabs, cerebrospinal fluid, urine and blood. In later stages, serological tests for antibody detection using ELISA are useful. Immuno-histochemistry on tissues collected after autopsy can also be performed. There is no specific treatment available for this infection and supportive therapy along with barrier nursing is mode of treatment. Monoclonal antibodies and vaccines against NiV have been found effective in animals but are yet to be tested in humans. The infection can be prevented in endemic areas by reducing exposure to fruit bats, pigs and date palm sap. Biology disease Nipah virus prevention and control treatment Medicine R Other systems of medicine In Journal of Mahatma Gandhi Institute of Medical Sciences Wolters Kluwer Medknow Publications, 2018 23(2018), 2, Seite 65-68 (DE-627)77127498X (DE-600)2738506-1 23471948 nnns volume:23 year:2018 number:2 pages:65-68 https://doi.org/10.4103/jmgims.jmgims_39_18 kostenfrei https://doaj.org/article/47896a9734ff4fcbac3989c028e4088e kostenfrei http://www.jmgims.co.in/article.asp?issn=0971-9903;year=2018;volume=23;issue=2;spage=65;epage=68;aulast=Narang kostenfrei https://doaj.org/toc/0971-9903 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 23 2018 2 65-68
allfieldsGer	10.4103/jmgims.jmgims_39_18 doi (DE-627)DOAJ023925604 (DE-599)DOAJ47896a9734ff4fcbac3989c028e4088e DE-627 ger DE-627 rakwb eng RZ201-999 Rahul Narang verfasserin aut Nipah virus: Biology, disease, treatment, control, and prevention 2018 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Nipah virus (NiV), an RNA virus, belongs to genus Henipahvirus of family Paramyxoviridiae. First isolated and identified in Malaysia in 1999, NiV affects humans as well as animals such as pigs, cattle, cats, dogs, ponies etc. Fruit bats of genus Pteropus serve as reservoir host for NiV. Bangladesh has experienced almost annual outbreaks while there have been few outbreaks in India, the latest was in Kerala state in 2018. NiV has become an important human pathogen causing acute encephalitis syndrome associated with high mortality. Central nervous and respiratory systems are involved mainly along with multi-organ vasculitis and infection of endothelial cells. In early stages of disease, laboratory diagnosis can be made by isolation as well as real time polymerase chain reaction (RT-PCR) from throat swabs, nasal swabs, cerebrospinal fluid, urine and blood. In later stages, serological tests for antibody detection using ELISA are useful. Immuno-histochemistry on tissues collected after autopsy can also be performed. There is no specific treatment available for this infection and supportive therapy along with barrier nursing is mode of treatment. Monoclonal antibodies and vaccines against NiV have been found effective in animals but are yet to be tested in humans. The infection can be prevented in endemic areas by reducing exposure to fruit bats, pigs and date palm sap. Biology disease Nipah virus prevention and control treatment Medicine R Other systems of medicine In Journal of Mahatma Gandhi Institute of Medical Sciences Wolters Kluwer Medknow Publications, 2018 23(2018), 2, Seite 65-68 (DE-627)77127498X (DE-600)2738506-1 23471948 nnns volume:23 year:2018 number:2 pages:65-68 https://doi.org/10.4103/jmgims.jmgims_39_18 kostenfrei https://doaj.org/article/47896a9734ff4fcbac3989c028e4088e kostenfrei http://www.jmgims.co.in/article.asp?issn=0971-9903;year=2018;volume=23;issue=2;spage=65;epage=68;aulast=Narang kostenfrei https://doaj.org/toc/0971-9903 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 23 2018 2 65-68
allfieldsSound	10.4103/jmgims.jmgims_39_18 doi (DE-627)DOAJ023925604 (DE-599)DOAJ47896a9734ff4fcbac3989c028e4088e DE-627 ger DE-627 rakwb eng RZ201-999 Rahul Narang verfasserin aut Nipah virus: Biology, disease, treatment, control, and prevention 2018 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Nipah virus (NiV), an RNA virus, belongs to genus Henipahvirus of family Paramyxoviridiae. First isolated and identified in Malaysia in 1999, NiV affects humans as well as animals such as pigs, cattle, cats, dogs, ponies etc. Fruit bats of genus Pteropus serve as reservoir host for NiV. Bangladesh has experienced almost annual outbreaks while there have been few outbreaks in India, the latest was in Kerala state in 2018. NiV has become an important human pathogen causing acute encephalitis syndrome associated with high mortality. Central nervous and respiratory systems are involved mainly along with multi-organ vasculitis and infection of endothelial cells. In early stages of disease, laboratory diagnosis can be made by isolation as well as real time polymerase chain reaction (RT-PCR) from throat swabs, nasal swabs, cerebrospinal fluid, urine and blood. In later stages, serological tests for antibody detection using ELISA are useful. Immuno-histochemistry on tissues collected after autopsy can also be performed. There is no specific treatment available for this infection and supportive therapy along with barrier nursing is mode of treatment. Monoclonal antibodies and vaccines against NiV have been found effective in animals but are yet to be tested in humans. The infection can be prevented in endemic areas by reducing exposure to fruit bats, pigs and date palm sap. Biology disease Nipah virus prevention and control treatment Medicine R Other systems of medicine In Journal of Mahatma Gandhi Institute of Medical Sciences Wolters Kluwer Medknow Publications, 2018 23(2018), 2, Seite 65-68 (DE-627)77127498X (DE-600)2738506-1 23471948 nnns volume:23 year:2018 number:2 pages:65-68 https://doi.org/10.4103/jmgims.jmgims_39_18 kostenfrei https://doaj.org/article/47896a9734ff4fcbac3989c028e4088e kostenfrei http://www.jmgims.co.in/article.asp?issn=0971-9903;year=2018;volume=23;issue=2;spage=65;epage=68;aulast=Narang kostenfrei https://doaj.org/toc/0971-9903 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 23 2018 2 65-68
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author	Rahul Narang
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title_sort	nipah virus: biology, disease, treatment, control, and prevention
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title_auth	Nipah virus: Biology, disease, treatment, control, and prevention
abstract	Nipah virus (NiV), an RNA virus, belongs to genus Henipahvirus of family Paramyxoviridiae. First isolated and identified in Malaysia in 1999, NiV affects humans as well as animals such as pigs, cattle, cats, dogs, ponies etc. Fruit bats of genus Pteropus serve as reservoir host for NiV. Bangladesh has experienced almost annual outbreaks while there have been few outbreaks in India, the latest was in Kerala state in 2018. NiV has become an important human pathogen causing acute encephalitis syndrome associated with high mortality. Central nervous and respiratory systems are involved mainly along with multi-organ vasculitis and infection of endothelial cells. In early stages of disease, laboratory diagnosis can be made by isolation as well as real time polymerase chain reaction (RT-PCR) from throat swabs, nasal swabs, cerebrospinal fluid, urine and blood. In later stages, serological tests for antibody detection using ELISA are useful. Immuno-histochemistry on tissues collected after autopsy can also be performed. There is no specific treatment available for this infection and supportive therapy along with barrier nursing is mode of treatment. Monoclonal antibodies and vaccines against NiV have been found effective in animals but are yet to be tested in humans. The infection can be prevented in endemic areas by reducing exposure to fruit bats, pigs and date palm sap.
abstractGer	Nipah virus (NiV), an RNA virus, belongs to genus Henipahvirus of family Paramyxoviridiae. First isolated and identified in Malaysia in 1999, NiV affects humans as well as animals such as pigs, cattle, cats, dogs, ponies etc. Fruit bats of genus Pteropus serve as reservoir host for NiV. Bangladesh has experienced almost annual outbreaks while there have been few outbreaks in India, the latest was in Kerala state in 2018. NiV has become an important human pathogen causing acute encephalitis syndrome associated with high mortality. Central nervous and respiratory systems are involved mainly along with multi-organ vasculitis and infection of endothelial cells. In early stages of disease, laboratory diagnosis can be made by isolation as well as real time polymerase chain reaction (RT-PCR) from throat swabs, nasal swabs, cerebrospinal fluid, urine and blood. In later stages, serological tests for antibody detection using ELISA are useful. Immuno-histochemistry on tissues collected after autopsy can also be performed. There is no specific treatment available for this infection and supportive therapy along with barrier nursing is mode of treatment. Monoclonal antibodies and vaccines against NiV have been found effective in animals but are yet to be tested in humans. The infection can be prevented in endemic areas by reducing exposure to fruit bats, pigs and date palm sap.
abstract_unstemmed	Nipah virus (NiV), an RNA virus, belongs to genus Henipahvirus of family Paramyxoviridiae. First isolated and identified in Malaysia in 1999, NiV affects humans as well as animals such as pigs, cattle, cats, dogs, ponies etc. Fruit bats of genus Pteropus serve as reservoir host for NiV. Bangladesh has experienced almost annual outbreaks while there have been few outbreaks in India, the latest was in Kerala state in 2018. NiV has become an important human pathogen causing acute encephalitis syndrome associated with high mortality. Central nervous and respiratory systems are involved mainly along with multi-organ vasculitis and infection of endothelial cells. In early stages of disease, laboratory diagnosis can be made by isolation as well as real time polymerase chain reaction (RT-PCR) from throat swabs, nasal swabs, cerebrospinal fluid, urine and blood. In later stages, serological tests for antibody detection using ELISA are useful. Immuno-histochemistry on tissues collected after autopsy can also be performed. There is no specific treatment available for this infection and supportive therapy along with barrier nursing is mode of treatment. Monoclonal antibodies and vaccines against NiV have been found effective in animals but are yet to be tested in humans. The infection can be prevented in endemic areas by reducing exposure to fruit bats, pigs and date palm sap.
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title_short	Nipah virus: Biology, disease, treatment, control, and prevention
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