Polyhydroyalkanoates: from Basic Research and Molecular Biology to Application

This review describes the Polyhydroxyalkanoate (PHA), an intracellular biodegradable microbial polymer. PHAs is formed from different types of three hydroxyalkanoic acids monomers, each unit forms an ester bond with the hydroxyl group of the other one and the hydroxyl substituted carbon has R co...
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Autor*in:	Amro Abd alFattah Amara [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2010

Übergeordnetes Werk:	In: International Islamic University Malaysia Engineering Journal - IIUM Press, International Islamic University Malaysia, 2015, 9(2010), 1
Übergeordnetes Werk:	volume:9 ; year:2010 ; number:1

Links:	Link aufrufen Link aufrufen Link aufrufen Journal toc Journal toc

DOI / URN:	10.31436/iiumej.v9i1.95

Katalog-ID:	DOAJ024419710

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spelling	10.31436/iiumej.v9i1.95 doi (DE-627)DOAJ024419710 (DE-599)DOAJb178c9980668447eb325636ef1af11ef DE-627 ger DE-627 rakwb eng TA1-2040 Amro Abd alFattah Amara verfasserin aut Polyhydroyalkanoates: from Basic Research and Molecular Biology to Application 2010 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier This review describes the Polyhydroxyalkanoate (PHA), an intracellular biodegradable microbial polymer. PHAs is formed from different types of three hydroxyalkanoic acids monomers, each unit forms an ester bond with the hydroxyl group of the other one and the hydroxyl substituted carbon has R configuration. The C-3 atom in β position is branched with at least one carbon atom in the form of methyl group (C1) to thirteen carbons in the form of tridecyl (C13). This alkyl side chain is not necessarily saturated. PHAs are biosynthesized through regulated pathways by specific enzymes. PHAs are accumulated in bacterial cells from soluble to insoluble form as storage materials inside the inclusion bodies during unbalanced nutrition or to save organisms from reducing equivalents. PHAs are converted again to soluble components by PHAs depolymerases and the degraded materials enter various metabolic pathways. Until now, four classes of enzymes responsible for PHAs polymerization are known. PHAs were well studied regarding their promising applications, physical, chemical and biological properties. PHAs are biodegradable, biocompatible, have good material properties, renewable and can be used in many applications. The most limiting factor in PHAs commercialization is their high cost compared to the petroleum plastics. This review highlights the new knowledge and that established by the pioneers in this field as well as the factors, which affect PHAs commercialization. Engineering (General). Civil engineering (General) In International Islamic University Malaysia Engineering Journal IIUM Press, International Islamic University Malaysia, 2015 9(2010), 1 (DE-627)1010842064 22897860 nnns volume:9 year:2010 number:1 https://doi.org/10.31436/iiumej.v9i1.95 kostenfrei https://doaj.org/article/b178c9980668447eb325636ef1af11ef kostenfrei http://journals.iium.edu.my/ejournal/index.php/iiumej/article/view/95 kostenfrei https://doaj.org/toc/1511-788X Journal toc kostenfrei https://doaj.org/toc/2289-7860 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 9 2010 1
allfields_unstemmed	10.31436/iiumej.v9i1.95 doi (DE-627)DOAJ024419710 (DE-599)DOAJb178c9980668447eb325636ef1af11ef DE-627 ger DE-627 rakwb eng TA1-2040 Amro Abd alFattah Amara verfasserin aut Polyhydroyalkanoates: from Basic Research and Molecular Biology to Application 2010 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier This review describes the Polyhydroxyalkanoate (PHA), an intracellular biodegradable microbial polymer. PHAs is formed from different types of three hydroxyalkanoic acids monomers, each unit forms an ester bond with the hydroxyl group of the other one and the hydroxyl substituted carbon has R configuration. The C-3 atom in β position is branched with at least one carbon atom in the form of methyl group (C1) to thirteen carbons in the form of tridecyl (C13). This alkyl side chain is not necessarily saturated. PHAs are biosynthesized through regulated pathways by specific enzymes. PHAs are accumulated in bacterial cells from soluble to insoluble form as storage materials inside the inclusion bodies during unbalanced nutrition or to save organisms from reducing equivalents. PHAs are converted again to soluble components by PHAs depolymerases and the degraded materials enter various metabolic pathways. Until now, four classes of enzymes responsible for PHAs polymerization are known. PHAs were well studied regarding their promising applications, physical, chemical and biological properties. PHAs are biodegradable, biocompatible, have good material properties, renewable and can be used in many applications. The most limiting factor in PHAs commercialization is their high cost compared to the petroleum plastics. This review highlights the new knowledge and that established by the pioneers in this field as well as the factors, which affect PHAs commercialization. Engineering (General). Civil engineering (General) In International Islamic University Malaysia Engineering Journal IIUM Press, International Islamic University Malaysia, 2015 9(2010), 1 (DE-627)1010842064 22897860 nnns volume:9 year:2010 number:1 https://doi.org/10.31436/iiumej.v9i1.95 kostenfrei https://doaj.org/article/b178c9980668447eb325636ef1af11ef kostenfrei http://journals.iium.edu.my/ejournal/index.php/iiumej/article/view/95 kostenfrei https://doaj.org/toc/1511-788X Journal toc kostenfrei https://doaj.org/toc/2289-7860 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 9 2010 1
allfieldsGer	10.31436/iiumej.v9i1.95 doi (DE-627)DOAJ024419710 (DE-599)DOAJb178c9980668447eb325636ef1af11ef DE-627 ger DE-627 rakwb eng TA1-2040 Amro Abd alFattah Amara verfasserin aut Polyhydroyalkanoates: from Basic Research and Molecular Biology to Application 2010 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier This review describes the Polyhydroxyalkanoate (PHA), an intracellular biodegradable microbial polymer. PHAs is formed from different types of three hydroxyalkanoic acids monomers, each unit forms an ester bond with the hydroxyl group of the other one and the hydroxyl substituted carbon has R configuration. The C-3 atom in β position is branched with at least one carbon atom in the form of methyl group (C1) to thirteen carbons in the form of tridecyl (C13). This alkyl side chain is not necessarily saturated. PHAs are biosynthesized through regulated pathways by specific enzymes. PHAs are accumulated in bacterial cells from soluble to insoluble form as storage materials inside the inclusion bodies during unbalanced nutrition or to save organisms from reducing equivalents. PHAs are converted again to soluble components by PHAs depolymerases and the degraded materials enter various metabolic pathways. Until now, four classes of enzymes responsible for PHAs polymerization are known. PHAs were well studied regarding their promising applications, physical, chemical and biological properties. PHAs are biodegradable, biocompatible, have good material properties, renewable and can be used in many applications. The most limiting factor in PHAs commercialization is their high cost compared to the petroleum plastics. This review highlights the new knowledge and that established by the pioneers in this field as well as the factors, which affect PHAs commercialization. Engineering (General). Civil engineering (General) In International Islamic University Malaysia Engineering Journal IIUM Press, International Islamic University Malaysia, 2015 9(2010), 1 (DE-627)1010842064 22897860 nnns volume:9 year:2010 number:1 https://doi.org/10.31436/iiumej.v9i1.95 kostenfrei https://doaj.org/article/b178c9980668447eb325636ef1af11ef kostenfrei http://journals.iium.edu.my/ejournal/index.php/iiumej/article/view/95 kostenfrei https://doaj.org/toc/1511-788X Journal toc kostenfrei https://doaj.org/toc/2289-7860 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 9 2010 1
allfieldsSound	10.31436/iiumej.v9i1.95 doi (DE-627)DOAJ024419710 (DE-599)DOAJb178c9980668447eb325636ef1af11ef DE-627 ger DE-627 rakwb eng TA1-2040 Amro Abd alFattah Amara verfasserin aut Polyhydroyalkanoates: from Basic Research and Molecular Biology to Application 2010 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier This review describes the Polyhydroxyalkanoate (PHA), an intracellular biodegradable microbial polymer. PHAs is formed from different types of three hydroxyalkanoic acids monomers, each unit forms an ester bond with the hydroxyl group of the other one and the hydroxyl substituted carbon has R configuration. The C-3 atom in β position is branched with at least one carbon atom in the form of methyl group (C1) to thirteen carbons in the form of tridecyl (C13). This alkyl side chain is not necessarily saturated. PHAs are biosynthesized through regulated pathways by specific enzymes. PHAs are accumulated in bacterial cells from soluble to insoluble form as storage materials inside the inclusion bodies during unbalanced nutrition or to save organisms from reducing equivalents. PHAs are converted again to soluble components by PHAs depolymerases and the degraded materials enter various metabolic pathways. Until now, four classes of enzymes responsible for PHAs polymerization are known. PHAs were well studied regarding their promising applications, physical, chemical and biological properties. PHAs are biodegradable, biocompatible, have good material properties, renewable and can be used in many applications. The most limiting factor in PHAs commercialization is their high cost compared to the petroleum plastics. This review highlights the new knowledge and that established by the pioneers in this field as well as the factors, which affect PHAs commercialization. Engineering (General). Civil engineering (General) In International Islamic University Malaysia Engineering Journal IIUM Press, International Islamic University Malaysia, 2015 9(2010), 1 (DE-627)1010842064 22897860 nnns volume:9 year:2010 number:1 https://doi.org/10.31436/iiumej.v9i1.95 kostenfrei https://doaj.org/article/b178c9980668447eb325636ef1af11ef kostenfrei http://journals.iium.edu.my/ejournal/index.php/iiumej/article/view/95 kostenfrei https://doaj.org/toc/1511-788X Journal toc kostenfrei https://doaj.org/toc/2289-7860 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_370 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4335 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 9 2010 1
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title	Polyhydroyalkanoates: from Basic Research and Molecular Biology to Application
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title_auth	Polyhydroyalkanoates: from Basic Research and Molecular Biology to Application
abstract	This review describes the Polyhydroxyalkanoate (PHA), an intracellular biodegradable microbial polymer. PHAs is formed from different types of three hydroxyalkanoic acids monomers, each unit forms an ester bond with the hydroxyl group of the other one and the hydroxyl substituted carbon has R configuration. The C-3 atom in β position is branched with at least one carbon atom in the form of methyl group (C1) to thirteen carbons in the form of tridecyl (C13). This alkyl side chain is not necessarily saturated. PHAs are biosynthesized through regulated pathways by specific enzymes. PHAs are accumulated in bacterial cells from soluble to insoluble form as storage materials inside the inclusion bodies during unbalanced nutrition or to save organisms from reducing equivalents. PHAs are converted again to soluble components by PHAs depolymerases and the degraded materials enter various metabolic pathways. Until now, four classes of enzymes responsible for PHAs polymerization are known. PHAs were well studied regarding their promising applications, physical, chemical and biological properties. PHAs are biodegradable, biocompatible, have good material properties, renewable and can be used in many applications. The most limiting factor in PHAs commercialization is their high cost compared to the petroleum plastics. This review highlights the new knowledge and that established by the pioneers in this field as well as the factors, which affect PHAs commercialization.
abstractGer	This review describes the Polyhydroxyalkanoate (PHA), an intracellular biodegradable microbial polymer. PHAs is formed from different types of three hydroxyalkanoic acids monomers, each unit forms an ester bond with the hydroxyl group of the other one and the hydroxyl substituted carbon has R configuration. The C-3 atom in β position is branched with at least one carbon atom in the form of methyl group (C1) to thirteen carbons in the form of tridecyl (C13). This alkyl side chain is not necessarily saturated. PHAs are biosynthesized through regulated pathways by specific enzymes. PHAs are accumulated in bacterial cells from soluble to insoluble form as storage materials inside the inclusion bodies during unbalanced nutrition or to save organisms from reducing equivalents. PHAs are converted again to soluble components by PHAs depolymerases and the degraded materials enter various metabolic pathways. Until now, four classes of enzymes responsible for PHAs polymerization are known. PHAs were well studied regarding their promising applications, physical, chemical and biological properties. PHAs are biodegradable, biocompatible, have good material properties, renewable and can be used in many applications. The most limiting factor in PHAs commercialization is their high cost compared to the petroleum plastics. This review highlights the new knowledge and that established by the pioneers in this field as well as the factors, which affect PHAs commercialization.
abstract_unstemmed	This review describes the Polyhydroxyalkanoate (PHA), an intracellular biodegradable microbial polymer. PHAs is formed from different types of three hydroxyalkanoic acids monomers, each unit forms an ester bond with the hydroxyl group of the other one and the hydroxyl substituted carbon has R configuration. The C-3 atom in β position is branched with at least one carbon atom in the form of methyl group (C1) to thirteen carbons in the form of tridecyl (C13). This alkyl side chain is not necessarily saturated. PHAs are biosynthesized through regulated pathways by specific enzymes. PHAs are accumulated in bacterial cells from soluble to insoluble form as storage materials inside the inclusion bodies during unbalanced nutrition or to save organisms from reducing equivalents. PHAs are converted again to soluble components by PHAs depolymerases and the degraded materials enter various metabolic pathways. Until now, four classes of enzymes responsible for PHAs polymerization are known. PHAs were well studied regarding their promising applications, physical, chemical and biological properties. PHAs are biodegradable, biocompatible, have good material properties, renewable and can be used in many applications. The most limiting factor in PHAs commercialization is their high cost compared to the petroleum plastics. This review highlights the new knowledge and that established by the pioneers in this field as well as the factors, which affect PHAs commercialization.
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title_short	Polyhydroyalkanoates: from Basic Research and Molecular Biology to Application
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score	7.3998165

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Polyhydroyalkanoates: from Basic Research and Molecular Biology to Application

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