Toksisitas Ekstrak Etanol dan Ekstrak Air dari Daun Jotang Kuda (Synedrella nodiflora (L.) Gaertn.), Daun Gandarusa (Justicia Gendarussa Burm.F.), dan Daun Pulutan (Urena lobata L.) dengan Brine Shrimp Lethality Test
Jotang kuda (Synedrella nodiflora (L.) Gaertn.), gandarusa (Justicia gendarussa Burm.f.) and pulutan (Urena lobata L.) leaves are used by several tribes in Central Sulawesi for the treatment of cancer. This study aims to determine the value of LC50 (Lethal Concentration 50) of ethanol and water extr...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Agustinus Widodo [verfasserIn] Akhmad Khumaidi [verfasserIn] Putri Faradila A. Lasongke [verfasserIn] |
|---|
| Format: |
E-Artikel |
|---|---|
| Sprache: |
Englisch ; Indonesisch |
| Erschienen: |
2019 |
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| Schlagwörter: |
synedrella nodiflora (l.) gaertn., justicia gendarussa burm. f., urena lobata l., bslt, lc50 |
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| Übergeordnetes Werk: |
In: Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) - Universitas Tadulako, 2018, 5(2019), 2, Seite 198-205 |
|---|---|
| Übergeordnetes Werk: |
volume:5 ; year:2019 ; number:2 ; pages:198-205 |
| Links: |
Link aufrufen |
|---|
| DOI / URN: |
10.22487/j24428744.2019.v5.i2.13935 |
|---|
| Katalog-ID: |
DOAJ025045008 |
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| 520 | |a Jotang kuda (Synedrella nodiflora (L.) Gaertn.), gandarusa (Justicia gendarussa Burm.f.) and pulutan (Urena lobata L.) leaves are used by several tribes in Central Sulawesi for the treatment of cancer. This study aims to determine the value of LC50 (Lethal Concentration 50) of ethanol and water extracts from the S. nodiflora, J. gendarussa and U. lobata leaves and identify the class of chemical compounds contained in extracts with the highest toxicity. The ethanol extract was obtained by the maceration method using ethanol 96% and the water extract was obtained by the infusion method. The extract toxicity test was carried out byBrine Shrimp Lethality Test (BSLT) and dentification test was carried out by Thin Layer Chromatography (TLC). The toxicity test results (LC50) of 96% ethanol extract and water extract of S. nodiflora leaves were 395.60 μg/ml and 109.25 μg/ml; J. gendarussa leaves 713.34 μg/ml and 18.02 μg/ml; and U. lobata leaves 188.38 μg/ml and 85.37 μg/ml, respectively. The results of identification showed that the water extract of the J. gendarussa leaves containing alkaloids, flavonoids, phenolics, saponins, and steroids-terpenoids. The results of this study indicated that the extracts of S. nodiflora leaves, J. gendarussa leaves, and U. lobata leaves are potential to be developed as anticancer. | ||
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10.22487/j24428744.2019.v5.i2.13935 doi (DE-627)DOAJ025045008 (DE-599)DOAJ9697b2bdf0234d1da139a27e7fb58392 DE-627 ger DE-627 rakwb eng ind RM1-950 Agustinus Widodo verfasserin aut Toksisitas Ekstrak Etanol dan Ekstrak Air dari Daun Jotang Kuda (Synedrella nodiflora (L.) Gaertn.), Daun Gandarusa (Justicia Gendarussa Burm.F.), dan Daun Pulutan (Urena lobata L.) dengan Brine Shrimp Lethality Test 2019 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Jotang kuda (Synedrella nodiflora (L.) Gaertn.), gandarusa (Justicia gendarussa Burm.f.) and pulutan (Urena lobata L.) leaves are used by several tribes in Central Sulawesi for the treatment of cancer. This study aims to determine the value of LC50 (Lethal Concentration 50) of ethanol and water extracts from the S. nodiflora, J. gendarussa and U. lobata leaves and identify the class of chemical compounds contained in extracts with the highest toxicity. The ethanol extract was obtained by the maceration method using ethanol 96% and the water extract was obtained by the infusion method. The extract toxicity test was carried out byBrine Shrimp Lethality Test (BSLT) and dentification test was carried out by Thin Layer Chromatography (TLC). The toxicity test results (LC50) of 96% ethanol extract and water extract of S. nodiflora leaves were 395.60 μg/ml and 109.25 μg/ml; J. gendarussa leaves 713.34 μg/ml and 18.02 μg/ml; and U. lobata leaves 188.38 μg/ml and 85.37 μg/ml, respectively. The results of identification showed that the water extract of the J. gendarussa leaves containing alkaloids, flavonoids, phenolics, saponins, and steroids-terpenoids. The results of this study indicated that the extracts of S. nodiflora leaves, J. gendarussa leaves, and U. lobata leaves are potential to be developed as anticancer. synedrella nodiflora (l.) gaertn., justicia gendarussa burm. f., urena lobata l., bslt, lc50 Therapeutics. Pharmacology Akhmad Khumaidi verfasserin aut Putri Faradila A. Lasongke verfasserin aut In Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) Universitas Tadulako, 2018 5(2019), 2, Seite 198-205 (DE-627)1760615722 24428744 nnns volume:5 year:2019 number:2 pages:198-205 https://doi.org/10.22487/j24428744.2019.v5.i2.13935 kostenfrei https://doaj.org/article/9697b2bdf0234d1da139a27e7fb58392 kostenfrei http://jurnal.untad.ac.id/jurnal/index.php/Galenika/article/view/13935 kostenfrei https://doaj.org/toc/2442-7284 Journal toc kostenfrei https://doaj.org/toc/2442-8744 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ AR 5 2019 2 198-205 |
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10.22487/j24428744.2019.v5.i2.13935 doi (DE-627)DOAJ025045008 (DE-599)DOAJ9697b2bdf0234d1da139a27e7fb58392 DE-627 ger DE-627 rakwb eng ind RM1-950 Agustinus Widodo verfasserin aut Toksisitas Ekstrak Etanol dan Ekstrak Air dari Daun Jotang Kuda (Synedrella nodiflora (L.) Gaertn.), Daun Gandarusa (Justicia Gendarussa Burm.F.), dan Daun Pulutan (Urena lobata L.) dengan Brine Shrimp Lethality Test 2019 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Jotang kuda (Synedrella nodiflora (L.) Gaertn.), gandarusa (Justicia gendarussa Burm.f.) and pulutan (Urena lobata L.) leaves are used by several tribes in Central Sulawesi for the treatment of cancer. This study aims to determine the value of LC50 (Lethal Concentration 50) of ethanol and water extracts from the S. nodiflora, J. gendarussa and U. lobata leaves and identify the class of chemical compounds contained in extracts with the highest toxicity. The ethanol extract was obtained by the maceration method using ethanol 96% and the water extract was obtained by the infusion method. The extract toxicity test was carried out byBrine Shrimp Lethality Test (BSLT) and dentification test was carried out by Thin Layer Chromatography (TLC). The toxicity test results (LC50) of 96% ethanol extract and water extract of S. nodiflora leaves were 395.60 μg/ml and 109.25 μg/ml; J. gendarussa leaves 713.34 μg/ml and 18.02 μg/ml; and U. lobata leaves 188.38 μg/ml and 85.37 μg/ml, respectively. The results of identification showed that the water extract of the J. gendarussa leaves containing alkaloids, flavonoids, phenolics, saponins, and steroids-terpenoids. The results of this study indicated that the extracts of S. nodiflora leaves, J. gendarussa leaves, and U. lobata leaves are potential to be developed as anticancer. synedrella nodiflora (l.) gaertn., justicia gendarussa burm. f., urena lobata l., bslt, lc50 Therapeutics. Pharmacology Akhmad Khumaidi verfasserin aut Putri Faradila A. Lasongke verfasserin aut In Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) Universitas Tadulako, 2018 5(2019), 2, Seite 198-205 (DE-627)1760615722 24428744 nnns volume:5 year:2019 number:2 pages:198-205 https://doi.org/10.22487/j24428744.2019.v5.i2.13935 kostenfrei https://doaj.org/article/9697b2bdf0234d1da139a27e7fb58392 kostenfrei http://jurnal.untad.ac.id/jurnal/index.php/Galenika/article/view/13935 kostenfrei https://doaj.org/toc/2442-7284 Journal toc kostenfrei https://doaj.org/toc/2442-8744 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ AR 5 2019 2 198-205 |
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10.22487/j24428744.2019.v5.i2.13935 doi (DE-627)DOAJ025045008 (DE-599)DOAJ9697b2bdf0234d1da139a27e7fb58392 DE-627 ger DE-627 rakwb eng ind RM1-950 Agustinus Widodo verfasserin aut Toksisitas Ekstrak Etanol dan Ekstrak Air dari Daun Jotang Kuda (Synedrella nodiflora (L.) Gaertn.), Daun Gandarusa (Justicia Gendarussa Burm.F.), dan Daun Pulutan (Urena lobata L.) dengan Brine Shrimp Lethality Test 2019 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Jotang kuda (Synedrella nodiflora (L.) Gaertn.), gandarusa (Justicia gendarussa Burm.f.) and pulutan (Urena lobata L.) leaves are used by several tribes in Central Sulawesi for the treatment of cancer. This study aims to determine the value of LC50 (Lethal Concentration 50) of ethanol and water extracts from the S. nodiflora, J. gendarussa and U. lobata leaves and identify the class of chemical compounds contained in extracts with the highest toxicity. The ethanol extract was obtained by the maceration method using ethanol 96% and the water extract was obtained by the infusion method. The extract toxicity test was carried out byBrine Shrimp Lethality Test (BSLT) and dentification test was carried out by Thin Layer Chromatography (TLC). The toxicity test results (LC50) of 96% ethanol extract and water extract of S. nodiflora leaves were 395.60 μg/ml and 109.25 μg/ml; J. gendarussa leaves 713.34 μg/ml and 18.02 μg/ml; and U. lobata leaves 188.38 μg/ml and 85.37 μg/ml, respectively. The results of identification showed that the water extract of the J. gendarussa leaves containing alkaloids, flavonoids, phenolics, saponins, and steroids-terpenoids. The results of this study indicated that the extracts of S. nodiflora leaves, J. gendarussa leaves, and U. lobata leaves are potential to be developed as anticancer. synedrella nodiflora (l.) gaertn., justicia gendarussa burm. f., urena lobata l., bslt, lc50 Therapeutics. Pharmacology Akhmad Khumaidi verfasserin aut Putri Faradila A. Lasongke verfasserin aut In Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) Universitas Tadulako, 2018 5(2019), 2, Seite 198-205 (DE-627)1760615722 24428744 nnns volume:5 year:2019 number:2 pages:198-205 https://doi.org/10.22487/j24428744.2019.v5.i2.13935 kostenfrei https://doaj.org/article/9697b2bdf0234d1da139a27e7fb58392 kostenfrei http://jurnal.untad.ac.id/jurnal/index.php/Galenika/article/view/13935 kostenfrei https://doaj.org/toc/2442-7284 Journal toc kostenfrei https://doaj.org/toc/2442-8744 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ AR 5 2019 2 198-205 |
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10.22487/j24428744.2019.v5.i2.13935 doi (DE-627)DOAJ025045008 (DE-599)DOAJ9697b2bdf0234d1da139a27e7fb58392 DE-627 ger DE-627 rakwb eng ind RM1-950 Agustinus Widodo verfasserin aut Toksisitas Ekstrak Etanol dan Ekstrak Air dari Daun Jotang Kuda (Synedrella nodiflora (L.) Gaertn.), Daun Gandarusa (Justicia Gendarussa Burm.F.), dan Daun Pulutan (Urena lobata L.) dengan Brine Shrimp Lethality Test 2019 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Jotang kuda (Synedrella nodiflora (L.) Gaertn.), gandarusa (Justicia gendarussa Burm.f.) and pulutan (Urena lobata L.) leaves are used by several tribes in Central Sulawesi for the treatment of cancer. This study aims to determine the value of LC50 (Lethal Concentration 50) of ethanol and water extracts from the S. nodiflora, J. gendarussa and U. lobata leaves and identify the class of chemical compounds contained in extracts with the highest toxicity. The ethanol extract was obtained by the maceration method using ethanol 96% and the water extract was obtained by the infusion method. The extract toxicity test was carried out byBrine Shrimp Lethality Test (BSLT) and dentification test was carried out by Thin Layer Chromatography (TLC). The toxicity test results (LC50) of 96% ethanol extract and water extract of S. nodiflora leaves were 395.60 μg/ml and 109.25 μg/ml; J. gendarussa leaves 713.34 μg/ml and 18.02 μg/ml; and U. lobata leaves 188.38 μg/ml and 85.37 μg/ml, respectively. The results of identification showed that the water extract of the J. gendarussa leaves containing alkaloids, flavonoids, phenolics, saponins, and steroids-terpenoids. The results of this study indicated that the extracts of S. nodiflora leaves, J. gendarussa leaves, and U. lobata leaves are potential to be developed as anticancer. synedrella nodiflora (l.) gaertn., justicia gendarussa burm. f., urena lobata l., bslt, lc50 Therapeutics. Pharmacology Akhmad Khumaidi verfasserin aut Putri Faradila A. Lasongke verfasserin aut In Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) Universitas Tadulako, 2018 5(2019), 2, Seite 198-205 (DE-627)1760615722 24428744 nnns volume:5 year:2019 number:2 pages:198-205 https://doi.org/10.22487/j24428744.2019.v5.i2.13935 kostenfrei https://doaj.org/article/9697b2bdf0234d1da139a27e7fb58392 kostenfrei http://jurnal.untad.ac.id/jurnal/index.php/Galenika/article/view/13935 kostenfrei https://doaj.org/toc/2442-7284 Journal toc kostenfrei https://doaj.org/toc/2442-8744 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ AR 5 2019 2 198-205 |
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10.22487/j24428744.2019.v5.i2.13935 doi (DE-627)DOAJ025045008 (DE-599)DOAJ9697b2bdf0234d1da139a27e7fb58392 DE-627 ger DE-627 rakwb eng ind RM1-950 Agustinus Widodo verfasserin aut Toksisitas Ekstrak Etanol dan Ekstrak Air dari Daun Jotang Kuda (Synedrella nodiflora (L.) Gaertn.), Daun Gandarusa (Justicia Gendarussa Burm.F.), dan Daun Pulutan (Urena lobata L.) dengan Brine Shrimp Lethality Test 2019 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Jotang kuda (Synedrella nodiflora (L.) Gaertn.), gandarusa (Justicia gendarussa Burm.f.) and pulutan (Urena lobata L.) leaves are used by several tribes in Central Sulawesi for the treatment of cancer. This study aims to determine the value of LC50 (Lethal Concentration 50) of ethanol and water extracts from the S. nodiflora, J. gendarussa and U. lobata leaves and identify the class of chemical compounds contained in extracts with the highest toxicity. The ethanol extract was obtained by the maceration method using ethanol 96% and the water extract was obtained by the infusion method. The extract toxicity test was carried out byBrine Shrimp Lethality Test (BSLT) and dentification test was carried out by Thin Layer Chromatography (TLC). The toxicity test results (LC50) of 96% ethanol extract and water extract of S. nodiflora leaves were 395.60 μg/ml and 109.25 μg/ml; J. gendarussa leaves 713.34 μg/ml and 18.02 μg/ml; and U. lobata leaves 188.38 μg/ml and 85.37 μg/ml, respectively. The results of identification showed that the water extract of the J. gendarussa leaves containing alkaloids, flavonoids, phenolics, saponins, and steroids-terpenoids. The results of this study indicated that the extracts of S. nodiflora leaves, J. gendarussa leaves, and U. lobata leaves are potential to be developed as anticancer. synedrella nodiflora (l.) gaertn., justicia gendarussa burm. f., urena lobata l., bslt, lc50 Therapeutics. Pharmacology Akhmad Khumaidi verfasserin aut Putri Faradila A. Lasongke verfasserin aut In Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) Universitas Tadulako, 2018 5(2019), 2, Seite 198-205 (DE-627)1760615722 24428744 nnns volume:5 year:2019 number:2 pages:198-205 https://doi.org/10.22487/j24428744.2019.v5.i2.13935 kostenfrei https://doaj.org/article/9697b2bdf0234d1da139a27e7fb58392 kostenfrei http://jurnal.untad.ac.id/jurnal/index.php/Galenika/article/view/13935 kostenfrei https://doaj.org/toc/2442-7284 Journal toc kostenfrei https://doaj.org/toc/2442-8744 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ AR 5 2019 2 198-205 |
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RM1-950 Toksisitas Ekstrak Etanol dan Ekstrak Air dari Daun Jotang Kuda (Synedrella nodiflora (L.) Gaertn.), Daun Gandarusa (Justicia Gendarussa Burm.F.), dan Daun Pulutan (Urena lobata L.) dengan Brine Shrimp Lethality Test synedrella nodiflora (l.) gaertn., justicia gendarussa burm. f., urena lobata l., bslt, lc50 |
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Toksisitas Ekstrak Etanol dan Ekstrak Air dari Daun Jotang Kuda (Synedrella nodiflora (L.) Gaertn.), Daun Gandarusa (Justicia Gendarussa Burm.F.), dan Daun Pulutan (Urena lobata L.) dengan Brine Shrimp Lethality Test |
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toksisitas ekstrak etanol dan ekstrak air dari daun jotang kuda (synedrella nodiflora (l.) gaertn.), daun gandarusa (justicia gendarussa burm.f.), dan daun pulutan (urena lobata l.) dengan brine shrimp lethality test |
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Toksisitas Ekstrak Etanol dan Ekstrak Air dari Daun Jotang Kuda (Synedrella nodiflora (L.) Gaertn.), Daun Gandarusa (Justicia Gendarussa Burm.F.), dan Daun Pulutan (Urena lobata L.) dengan Brine Shrimp Lethality Test |
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Jotang kuda (Synedrella nodiflora (L.) Gaertn.), gandarusa (Justicia gendarussa Burm.f.) and pulutan (Urena lobata L.) leaves are used by several tribes in Central Sulawesi for the treatment of cancer. This study aims to determine the value of LC50 (Lethal Concentration 50) of ethanol and water extracts from the S. nodiflora, J. gendarussa and U. lobata leaves and identify the class of chemical compounds contained in extracts with the highest toxicity. The ethanol extract was obtained by the maceration method using ethanol 96% and the water extract was obtained by the infusion method. The extract toxicity test was carried out byBrine Shrimp Lethality Test (BSLT) and dentification test was carried out by Thin Layer Chromatography (TLC). The toxicity test results (LC50) of 96% ethanol extract and water extract of S. nodiflora leaves were 395.60 μg/ml and 109.25 μg/ml; J. gendarussa leaves 713.34 μg/ml and 18.02 μg/ml; and U. lobata leaves 188.38 μg/ml and 85.37 μg/ml, respectively. The results of identification showed that the water extract of the J. gendarussa leaves containing alkaloids, flavonoids, phenolics, saponins, and steroids-terpenoids. The results of this study indicated that the extracts of S. nodiflora leaves, J. gendarussa leaves, and U. lobata leaves are potential to be developed as anticancer. |
| abstractGer |
Jotang kuda (Synedrella nodiflora (L.) Gaertn.), gandarusa (Justicia gendarussa Burm.f.) and pulutan (Urena lobata L.) leaves are used by several tribes in Central Sulawesi for the treatment of cancer. This study aims to determine the value of LC50 (Lethal Concentration 50) of ethanol and water extracts from the S. nodiflora, J. gendarussa and U. lobata leaves and identify the class of chemical compounds contained in extracts with the highest toxicity. The ethanol extract was obtained by the maceration method using ethanol 96% and the water extract was obtained by the infusion method. The extract toxicity test was carried out byBrine Shrimp Lethality Test (BSLT) and dentification test was carried out by Thin Layer Chromatography (TLC). The toxicity test results (LC50) of 96% ethanol extract and water extract of S. nodiflora leaves were 395.60 μg/ml and 109.25 μg/ml; J. gendarussa leaves 713.34 μg/ml and 18.02 μg/ml; and U. lobata leaves 188.38 μg/ml and 85.37 μg/ml, respectively. The results of identification showed that the water extract of the J. gendarussa leaves containing alkaloids, flavonoids, phenolics, saponins, and steroids-terpenoids. The results of this study indicated that the extracts of S. nodiflora leaves, J. gendarussa leaves, and U. lobata leaves are potential to be developed as anticancer. |
| abstract_unstemmed |
Jotang kuda (Synedrella nodiflora (L.) Gaertn.), gandarusa (Justicia gendarussa Burm.f.) and pulutan (Urena lobata L.) leaves are used by several tribes in Central Sulawesi for the treatment of cancer. This study aims to determine the value of LC50 (Lethal Concentration 50) of ethanol and water extracts from the S. nodiflora, J. gendarussa and U. lobata leaves and identify the class of chemical compounds contained in extracts with the highest toxicity. The ethanol extract was obtained by the maceration method using ethanol 96% and the water extract was obtained by the infusion method. The extract toxicity test was carried out byBrine Shrimp Lethality Test (BSLT) and dentification test was carried out by Thin Layer Chromatography (TLC). The toxicity test results (LC50) of 96% ethanol extract and water extract of S. nodiflora leaves were 395.60 μg/ml and 109.25 μg/ml; J. gendarussa leaves 713.34 μg/ml and 18.02 μg/ml; and U. lobata leaves 188.38 μg/ml and 85.37 μg/ml, respectively. The results of identification showed that the water extract of the J. gendarussa leaves containing alkaloids, flavonoids, phenolics, saponins, and steroids-terpenoids. The results of this study indicated that the extracts of S. nodiflora leaves, J. gendarussa leaves, and U. lobata leaves are potential to be developed as anticancer. |
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