Preliminary experience of fractionated stereotactic radiosurgery with extend system of Gamma Knife
<p<Purpose: The purpose of this study is to present multisession stereotactic radiosurgery with initial experience using custom made extend system (ES) of Gamma Knife.</p<<p<Methods: The ES is comprised of a carbon fiber frame also called extend frame, vacuum head rest cushion, pat...
Ausführliche Beschreibung
Autor*in: |
Raj Bisht [verfasserIn] Shashank Kale [verfasserIn] Gopishankar Nathanasabapathi [verfasserIn] Pratik Kumar [verfasserIn] Manmohan Singh [verfasserIn] Deepak Agarwal [verfasserIn] Sanjay Thulkar [verfasserIn] Ajay Garg [verfasserIn] Pramod Julka [verfasserIn] Gaura Rath [verfasserIn] Bhawani Sharma [verfasserIn] |
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E-Artikel |
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Sprache: |
Englisch |
Erschienen: |
2016 |
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Übergeordnetes Werk: |
In: International Journal of Cancer Therapy and Oncology - IJCTO, 2015, 4(2016), 1 |
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Übergeordnetes Werk: |
volume:4 ; year:2016 ; number:1 |
Links: |
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DOI / URN: |
10.14319/ijcto.41.14 |
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Katalog-ID: |
DOAJ025287753 |
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10.14319/ijcto.41.14 doi (DE-627)DOAJ025287753 (DE-599)DOAJ79c874a71175411a8ecff6a314ead165 DE-627 ger DE-627 rakwb eng Raj Bisht verfasserin aut Preliminary experience of fractionated stereotactic radiosurgery with extend system of Gamma Knife 2016 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier <p<Purpose: The purpose of this study is to present multisession stereotactic radiosurgery with initial experience using custom made extend system (ES) of Gamma Knife.</p<<p<Methods: The ES is comprised of a carbon fiber frame also called extend frame, vacuum head rest cushion, patient surveillance unit and a configurable front piece with dental impression tray. The extend frame is a rigid connection between patient's head and patient positioning system (PPS) of Gamma Knife. A dental impression of patient was created and attached to the frontal piece of extend system. The treatment setup involves positioning the patient within the extend frame using patient specific headrest cushion and front piece. The reference patient’s head position was recorded through measurements of repositioning check tool (RCT) apertures using a high precision digital probe before computed tomography (CT) scan. The RCT measurements taken before treatment were compared with recorded reference position to ensure appropriate patient treatment position. Volumetric magnetic resonance (MR) scan was co-registered with stereotactic CT scan on Leksell Gamma plan. Fused MR to CT images on Gamma Plan was utilized to delineate regions of interest and prepare a precise treatment plan. The presented study includes positional reproducibility check and dosimetric evaluation of ten patients treated with ES.</p<<p<Results: Forty-three fractions on ten patients with prescribed treatment format were delivered successfully. An average tumor volume of 11.26 cm<sup<3</sup< (range, 340 mm<sup<3</sup< to 59.12 cm<sup<3</sup<) was treated with ES. The mean tumor coverage of 91.91% (range, 90% to 95%) was able to achieve at 50% prescription isodose without compromising adjacent normal structure radiation dose tolerances. The mean inter-fraction positional variation of 0.69 mm influences an inherent strength of immobilization technique. Follow-up of seven patients at a median interval of 16 months (range, 9 months to 26 months) showed evidence of 100% radiographic control with improved clinical results.</p<<p<Conclusion: Conjugative clinical outcome shows the efficacy of fractionation in various clinical indications.</p< Gamma Knife, Stereotactic Radiosurgery, Positional Accuracy Medicine R Shashank Kale verfasserin aut Gopishankar Nathanasabapathi verfasserin aut Pratik Kumar verfasserin aut Manmohan Singh verfasserin aut Deepak Agarwal verfasserin aut Sanjay Thulkar verfasserin aut Ajay Garg verfasserin aut Pramod Julka verfasserin aut Gaura Rath verfasserin aut Bhawani Sharma verfasserin aut In International Journal of Cancer Therapy and Oncology IJCTO, 2015 4(2016), 1 (DE-627)1760600458 (DE-600)3068719-6 23304049 nnns volume:4 year:2016 number:1 https://doi.org/10.14319/ijcto.41.14 kostenfrei https://doaj.org/article/79c874a71175411a8ecff6a314ead165 kostenfrei http://ijcto.org/index.php/IJCTO/article/view/454 kostenfrei https://doaj.org/toc/2330-4049 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ AR 4 2016 1 |
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10.14319/ijcto.41.14 doi (DE-627)DOAJ025287753 (DE-599)DOAJ79c874a71175411a8ecff6a314ead165 DE-627 ger DE-627 rakwb eng Raj Bisht verfasserin aut Preliminary experience of fractionated stereotactic radiosurgery with extend system of Gamma Knife 2016 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier <p<Purpose: The purpose of this study is to present multisession stereotactic radiosurgery with initial experience using custom made extend system (ES) of Gamma Knife.</p<<p<Methods: The ES is comprised of a carbon fiber frame also called extend frame, vacuum head rest cushion, patient surveillance unit and a configurable front piece with dental impression tray. The extend frame is a rigid connection between patient's head and patient positioning system (PPS) of Gamma Knife. A dental impression of patient was created and attached to the frontal piece of extend system. The treatment setup involves positioning the patient within the extend frame using patient specific headrest cushion and front piece. The reference patient’s head position was recorded through measurements of repositioning check tool (RCT) apertures using a high precision digital probe before computed tomography (CT) scan. The RCT measurements taken before treatment were compared with recorded reference position to ensure appropriate patient treatment position. Volumetric magnetic resonance (MR) scan was co-registered with stereotactic CT scan on Leksell Gamma plan. Fused MR to CT images on Gamma Plan was utilized to delineate regions of interest and prepare a precise treatment plan. The presented study includes positional reproducibility check and dosimetric evaluation of ten patients treated with ES.</p<<p<Results: Forty-three fractions on ten patients with prescribed treatment format were delivered successfully. An average tumor volume of 11.26 cm<sup<3</sup< (range, 340 mm<sup<3</sup< to 59.12 cm<sup<3</sup<) was treated with ES. The mean tumor coverage of 91.91% (range, 90% to 95%) was able to achieve at 50% prescription isodose without compromising adjacent normal structure radiation dose tolerances. The mean inter-fraction positional variation of 0.69 mm influences an inherent strength of immobilization technique. Follow-up of seven patients at a median interval of 16 months (range, 9 months to 26 months) showed evidence of 100% radiographic control with improved clinical results.</p<<p<Conclusion: Conjugative clinical outcome shows the efficacy of fractionation in various clinical indications.</p< Gamma Knife, Stereotactic Radiosurgery, Positional Accuracy Medicine R Shashank Kale verfasserin aut Gopishankar Nathanasabapathi verfasserin aut Pratik Kumar verfasserin aut Manmohan Singh verfasserin aut Deepak Agarwal verfasserin aut Sanjay Thulkar verfasserin aut Ajay Garg verfasserin aut Pramod Julka verfasserin aut Gaura Rath verfasserin aut Bhawani Sharma verfasserin aut In International Journal of Cancer Therapy and Oncology IJCTO, 2015 4(2016), 1 (DE-627)1760600458 (DE-600)3068719-6 23304049 nnns volume:4 year:2016 number:1 https://doi.org/10.14319/ijcto.41.14 kostenfrei https://doaj.org/article/79c874a71175411a8ecff6a314ead165 kostenfrei http://ijcto.org/index.php/IJCTO/article/view/454 kostenfrei https://doaj.org/toc/2330-4049 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ AR 4 2016 1 |
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10.14319/ijcto.41.14 doi (DE-627)DOAJ025287753 (DE-599)DOAJ79c874a71175411a8ecff6a314ead165 DE-627 ger DE-627 rakwb eng Raj Bisht verfasserin aut Preliminary experience of fractionated stereotactic radiosurgery with extend system of Gamma Knife 2016 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier <p<Purpose: The purpose of this study is to present multisession stereotactic radiosurgery with initial experience using custom made extend system (ES) of Gamma Knife.</p<<p<Methods: The ES is comprised of a carbon fiber frame also called extend frame, vacuum head rest cushion, patient surveillance unit and a configurable front piece with dental impression tray. The extend frame is a rigid connection between patient's head and patient positioning system (PPS) of Gamma Knife. A dental impression of patient was created and attached to the frontal piece of extend system. The treatment setup involves positioning the patient within the extend frame using patient specific headrest cushion and front piece. The reference patient’s head position was recorded through measurements of repositioning check tool (RCT) apertures using a high precision digital probe before computed tomography (CT) scan. The RCT measurements taken before treatment were compared with recorded reference position to ensure appropriate patient treatment position. Volumetric magnetic resonance (MR) scan was co-registered with stereotactic CT scan on Leksell Gamma plan. Fused MR to CT images on Gamma Plan was utilized to delineate regions of interest and prepare a precise treatment plan. The presented study includes positional reproducibility check and dosimetric evaluation of ten patients treated with ES.</p<<p<Results: Forty-three fractions on ten patients with prescribed treatment format were delivered successfully. An average tumor volume of 11.26 cm<sup<3</sup< (range, 340 mm<sup<3</sup< to 59.12 cm<sup<3</sup<) was treated with ES. The mean tumor coverage of 91.91% (range, 90% to 95%) was able to achieve at 50% prescription isodose without compromising adjacent normal structure radiation dose tolerances. The mean inter-fraction positional variation of 0.69 mm influences an inherent strength of immobilization technique. Follow-up of seven patients at a median interval of 16 months (range, 9 months to 26 months) showed evidence of 100% radiographic control with improved clinical results.</p<<p<Conclusion: Conjugative clinical outcome shows the efficacy of fractionation in various clinical indications.</p< Gamma Knife, Stereotactic Radiosurgery, Positional Accuracy Medicine R Shashank Kale verfasserin aut Gopishankar Nathanasabapathi verfasserin aut Pratik Kumar verfasserin aut Manmohan Singh verfasserin aut Deepak Agarwal verfasserin aut Sanjay Thulkar verfasserin aut Ajay Garg verfasserin aut Pramod Julka verfasserin aut Gaura Rath verfasserin aut Bhawani Sharma verfasserin aut In International Journal of Cancer Therapy and Oncology IJCTO, 2015 4(2016), 1 (DE-627)1760600458 (DE-600)3068719-6 23304049 nnns volume:4 year:2016 number:1 https://doi.org/10.14319/ijcto.41.14 kostenfrei https://doaj.org/article/79c874a71175411a8ecff6a314ead165 kostenfrei http://ijcto.org/index.php/IJCTO/article/view/454 kostenfrei https://doaj.org/toc/2330-4049 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ AR 4 2016 1 |
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10.14319/ijcto.41.14 doi (DE-627)DOAJ025287753 (DE-599)DOAJ79c874a71175411a8ecff6a314ead165 DE-627 ger DE-627 rakwb eng Raj Bisht verfasserin aut Preliminary experience of fractionated stereotactic radiosurgery with extend system of Gamma Knife 2016 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier <p<Purpose: The purpose of this study is to present multisession stereotactic radiosurgery with initial experience using custom made extend system (ES) of Gamma Knife.</p<<p<Methods: The ES is comprised of a carbon fiber frame also called extend frame, vacuum head rest cushion, patient surveillance unit and a configurable front piece with dental impression tray. The extend frame is a rigid connection between patient's head and patient positioning system (PPS) of Gamma Knife. A dental impression of patient was created and attached to the frontal piece of extend system. The treatment setup involves positioning the patient within the extend frame using patient specific headrest cushion and front piece. The reference patient’s head position was recorded through measurements of repositioning check tool (RCT) apertures using a high precision digital probe before computed tomography (CT) scan. The RCT measurements taken before treatment were compared with recorded reference position to ensure appropriate patient treatment position. Volumetric magnetic resonance (MR) scan was co-registered with stereotactic CT scan on Leksell Gamma plan. Fused MR to CT images on Gamma Plan was utilized to delineate regions of interest and prepare a precise treatment plan. The presented study includes positional reproducibility check and dosimetric evaluation of ten patients treated with ES.</p<<p<Results: Forty-three fractions on ten patients with prescribed treatment format were delivered successfully. An average tumor volume of 11.26 cm<sup<3</sup< (range, 340 mm<sup<3</sup< to 59.12 cm<sup<3</sup<) was treated with ES. The mean tumor coverage of 91.91% (range, 90% to 95%) was able to achieve at 50% prescription isodose without compromising adjacent normal structure radiation dose tolerances. The mean inter-fraction positional variation of 0.69 mm influences an inherent strength of immobilization technique. Follow-up of seven patients at a median interval of 16 months (range, 9 months to 26 months) showed evidence of 100% radiographic control with improved clinical results.</p<<p<Conclusion: Conjugative clinical outcome shows the efficacy of fractionation in various clinical indications.</p< Gamma Knife, Stereotactic Radiosurgery, Positional Accuracy Medicine R Shashank Kale verfasserin aut Gopishankar Nathanasabapathi verfasserin aut Pratik Kumar verfasserin aut Manmohan Singh verfasserin aut Deepak Agarwal verfasserin aut Sanjay Thulkar verfasserin aut Ajay Garg verfasserin aut Pramod Julka verfasserin aut Gaura Rath verfasserin aut Bhawani Sharma verfasserin aut In International Journal of Cancer Therapy and Oncology IJCTO, 2015 4(2016), 1 (DE-627)1760600458 (DE-600)3068719-6 23304049 nnns volume:4 year:2016 number:1 https://doi.org/10.14319/ijcto.41.14 kostenfrei https://doaj.org/article/79c874a71175411a8ecff6a314ead165 kostenfrei http://ijcto.org/index.php/IJCTO/article/view/454 kostenfrei https://doaj.org/toc/2330-4049 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ AR 4 2016 1 |
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10.14319/ijcto.41.14 doi (DE-627)DOAJ025287753 (DE-599)DOAJ79c874a71175411a8ecff6a314ead165 DE-627 ger DE-627 rakwb eng Raj Bisht verfasserin aut Preliminary experience of fractionated stereotactic radiosurgery with extend system of Gamma Knife 2016 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier <p<Purpose: The purpose of this study is to present multisession stereotactic radiosurgery with initial experience using custom made extend system (ES) of Gamma Knife.</p<<p<Methods: The ES is comprised of a carbon fiber frame also called extend frame, vacuum head rest cushion, patient surveillance unit and a configurable front piece with dental impression tray. The extend frame is a rigid connection between patient's head and patient positioning system (PPS) of Gamma Knife. A dental impression of patient was created and attached to the frontal piece of extend system. The treatment setup involves positioning the patient within the extend frame using patient specific headrest cushion and front piece. The reference patient’s head position was recorded through measurements of repositioning check tool (RCT) apertures using a high precision digital probe before computed tomography (CT) scan. The RCT measurements taken before treatment were compared with recorded reference position to ensure appropriate patient treatment position. Volumetric magnetic resonance (MR) scan was co-registered with stereotactic CT scan on Leksell Gamma plan. Fused MR to CT images on Gamma Plan was utilized to delineate regions of interest and prepare a precise treatment plan. The presented study includes positional reproducibility check and dosimetric evaluation of ten patients treated with ES.</p<<p<Results: Forty-three fractions on ten patients with prescribed treatment format were delivered successfully. An average tumor volume of 11.26 cm<sup<3</sup< (range, 340 mm<sup<3</sup< to 59.12 cm<sup<3</sup<) was treated with ES. The mean tumor coverage of 91.91% (range, 90% to 95%) was able to achieve at 50% prescription isodose without compromising adjacent normal structure radiation dose tolerances. The mean inter-fraction positional variation of 0.69 mm influences an inherent strength of immobilization technique. Follow-up of seven patients at a median interval of 16 months (range, 9 months to 26 months) showed evidence of 100% radiographic control with improved clinical results.</p<<p<Conclusion: Conjugative clinical outcome shows the efficacy of fractionation in various clinical indications.</p< Gamma Knife, Stereotactic Radiosurgery, Positional Accuracy Medicine R Shashank Kale verfasserin aut Gopishankar Nathanasabapathi verfasserin aut Pratik Kumar verfasserin aut Manmohan Singh verfasserin aut Deepak Agarwal verfasserin aut Sanjay Thulkar verfasserin aut Ajay Garg verfasserin aut Pramod Julka verfasserin aut Gaura Rath verfasserin aut Bhawani Sharma verfasserin aut In International Journal of Cancer Therapy and Oncology IJCTO, 2015 4(2016), 1 (DE-627)1760600458 (DE-600)3068719-6 23304049 nnns volume:4 year:2016 number:1 https://doi.org/10.14319/ijcto.41.14 kostenfrei https://doaj.org/article/79c874a71175411a8ecff6a314ead165 kostenfrei http://ijcto.org/index.php/IJCTO/article/view/454 kostenfrei https://doaj.org/toc/2330-4049 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ AR 4 2016 1 |
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Preliminary experience of fractionated stereotactic radiosurgery with extend system of Gamma Knife |
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<p<Purpose: The purpose of this study is to present multisession stereotactic radiosurgery with initial experience using custom made extend system (ES) of Gamma Knife.</p<<p<Methods: The ES is comprised of a carbon fiber frame also called extend frame, vacuum head rest cushion, patient surveillance unit and a configurable front piece with dental impression tray. The extend frame is a rigid connection between patient's head and patient positioning system (PPS) of Gamma Knife. A dental impression of patient was created and attached to the frontal piece of extend system. The treatment setup involves positioning the patient within the extend frame using patient specific headrest cushion and front piece. The reference patient’s head position was recorded through measurements of repositioning check tool (RCT) apertures using a high precision digital probe before computed tomography (CT) scan. The RCT measurements taken before treatment were compared with recorded reference position to ensure appropriate patient treatment position. Volumetric magnetic resonance (MR) scan was co-registered with stereotactic CT scan on Leksell Gamma plan. Fused MR to CT images on Gamma Plan was utilized to delineate regions of interest and prepare a precise treatment plan. The presented study includes positional reproducibility check and dosimetric evaluation of ten patients treated with ES.</p<<p<Results: Forty-three fractions on ten patients with prescribed treatment format were delivered successfully. An average tumor volume of 11.26 cm<sup<3</sup< (range, 340 mm<sup<3</sup< to 59.12 cm<sup<3</sup<) was treated with ES. The mean tumor coverage of 91.91% (range, 90% to 95%) was able to achieve at 50% prescription isodose without compromising adjacent normal structure radiation dose tolerances. The mean inter-fraction positional variation of 0.69 mm influences an inherent strength of immobilization technique. Follow-up of seven patients at a median interval of 16 months (range, 9 months to 26 months) showed evidence of 100% radiographic control with improved clinical results.</p<<p<Conclusion: Conjugative clinical outcome shows the efficacy of fractionation in various clinical indications.</p< |
abstractGer |
<p<Purpose: The purpose of this study is to present multisession stereotactic radiosurgery with initial experience using custom made extend system (ES) of Gamma Knife.</p<<p<Methods: The ES is comprised of a carbon fiber frame also called extend frame, vacuum head rest cushion, patient surveillance unit and a configurable front piece with dental impression tray. The extend frame is a rigid connection between patient's head and patient positioning system (PPS) of Gamma Knife. A dental impression of patient was created and attached to the frontal piece of extend system. The treatment setup involves positioning the patient within the extend frame using patient specific headrest cushion and front piece. The reference patient’s head position was recorded through measurements of repositioning check tool (RCT) apertures using a high precision digital probe before computed tomography (CT) scan. The RCT measurements taken before treatment were compared with recorded reference position to ensure appropriate patient treatment position. Volumetric magnetic resonance (MR) scan was co-registered with stereotactic CT scan on Leksell Gamma plan. Fused MR to CT images on Gamma Plan was utilized to delineate regions of interest and prepare a precise treatment plan. The presented study includes positional reproducibility check and dosimetric evaluation of ten patients treated with ES.</p<<p<Results: Forty-three fractions on ten patients with prescribed treatment format were delivered successfully. An average tumor volume of 11.26 cm<sup<3</sup< (range, 340 mm<sup<3</sup< to 59.12 cm<sup<3</sup<) was treated with ES. The mean tumor coverage of 91.91% (range, 90% to 95%) was able to achieve at 50% prescription isodose without compromising adjacent normal structure radiation dose tolerances. The mean inter-fraction positional variation of 0.69 mm influences an inherent strength of immobilization technique. Follow-up of seven patients at a median interval of 16 months (range, 9 months to 26 months) showed evidence of 100% radiographic control with improved clinical results.</p<<p<Conclusion: Conjugative clinical outcome shows the efficacy of fractionation in various clinical indications.</p< |
abstract_unstemmed |
<p<Purpose: The purpose of this study is to present multisession stereotactic radiosurgery with initial experience using custom made extend system (ES) of Gamma Knife.</p<<p<Methods: The ES is comprised of a carbon fiber frame also called extend frame, vacuum head rest cushion, patient surveillance unit and a configurable front piece with dental impression tray. The extend frame is a rigid connection between patient's head and patient positioning system (PPS) of Gamma Knife. A dental impression of patient was created and attached to the frontal piece of extend system. The treatment setup involves positioning the patient within the extend frame using patient specific headrest cushion and front piece. The reference patient’s head position was recorded through measurements of repositioning check tool (RCT) apertures using a high precision digital probe before computed tomography (CT) scan. The RCT measurements taken before treatment were compared with recorded reference position to ensure appropriate patient treatment position. Volumetric magnetic resonance (MR) scan was co-registered with stereotactic CT scan on Leksell Gamma plan. Fused MR to CT images on Gamma Plan was utilized to delineate regions of interest and prepare a precise treatment plan. The presented study includes positional reproducibility check and dosimetric evaluation of ten patients treated with ES.</p<<p<Results: Forty-three fractions on ten patients with prescribed treatment format were delivered successfully. An average tumor volume of 11.26 cm<sup<3</sup< (range, 340 mm<sup<3</sup< to 59.12 cm<sup<3</sup<) was treated with ES. The mean tumor coverage of 91.91% (range, 90% to 95%) was able to achieve at 50% prescription isodose without compromising adjacent normal structure radiation dose tolerances. The mean inter-fraction positional variation of 0.69 mm influences an inherent strength of immobilization technique. Follow-up of seven patients at a median interval of 16 months (range, 9 months to 26 months) showed evidence of 100% radiographic control with improved clinical results.</p<<p<Conclusion: Conjugative clinical outcome shows the efficacy of fractionation in various clinical indications.</p< |
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