Eunicellin-Based Diterpenoids, Hirsutalins N–R, from the Formosan Soft Coral Cladiella hirsuta

New eunicellin-type hirsutalins N–R (1–5), along with two known eunicellins, (6 and 7) were isolated from the soft coral Cladiella hirsuta. The structures of the metabolites were determined by extensive spectroscopic analysis. Cytotoxic activity of compounds 1–7 against the proliferation of a limite...
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Autor*in:	Tzu-Zin Huang [verfasserIn] Bo-Wei Chen [verfasserIn] Chiung-Yao Huang [verfasserIn] Tsong-Long Hwang [verfasserIn] Chang-Feng Dai [verfasserIn] Jyh-Horng Sheu [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2014

Schlagwörter:	soft coral Cladiella hirsuta eunicellins: cytotoxic activity anti-inflammatory activity

Übergeordnetes Werk:	In: Marine Drugs - MDPI AG, 2005, 12(2014), 5, Seite 2446-2457
Übergeordnetes Werk:	volume:12 ; year:2014 ; number:5 ; pages:2446-2457

Links:	Link aufrufen Link aufrufen Link aufrufen Journal toc

DOI / URN:	10.3390/md12052446

Katalog-ID:	DOAJ025925393

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source	In Marine Drugs 12(2014), 5, Seite 2446-2457 volume:12 year:2014 number:5 pages:2446-2457
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topic_facet	soft coral Cladiella hirsuta eunicellins: cytotoxic activity anti-inflammatory activity Biology (General)
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authorswithroles_txt_mv	Tzu-Zin Huang @@aut@@ Bo-Wei Chen @@aut@@ Chiung-Yao Huang @@aut@@ Tsong-Long Hwang @@aut@@ Chang-Feng Dai @@aut@@ Jyh-Horng Sheu @@aut@@
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callnumber-first	Q - Science
author	Tzu-Zin Huang
spellingShingle	Tzu-Zin Huang misc QH301-705.5 misc soft coral misc Cladiella hirsuta misc eunicellins: cytotoxic activity misc anti-inflammatory activity misc Biology (General) Eunicellin-Based Diterpenoids, Hirsutalins N–R, from the Formosan Soft Coral Cladiella hirsuta
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topic_title	QH301-705.5 Eunicellin-Based Diterpenoids, Hirsutalins N–R, from the Formosan Soft Coral Cladiella hirsuta soft coral Cladiella hirsuta eunicellins: cytotoxic activity anti-inflammatory activity
topic	misc QH301-705.5 misc soft coral misc Cladiella hirsuta misc eunicellins: cytotoxic activity misc anti-inflammatory activity misc Biology (General)
topic_unstemmed	misc QH301-705.5 misc soft coral misc Cladiella hirsuta misc eunicellins: cytotoxic activity misc anti-inflammatory activity misc Biology (General)
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title	Eunicellin-Based Diterpenoids, Hirsutalins N–R, from the Formosan Soft Coral Cladiella hirsuta
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title_full	Eunicellin-Based Diterpenoids, Hirsutalins N–R, from the Formosan Soft Coral Cladiella hirsuta
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title_sort	eunicellin-based diterpenoids, hirsutalins n–r, from the formosan soft coral cladiella hirsuta
callnumber	QH301-705.5
title_auth	Eunicellin-Based Diterpenoids, Hirsutalins N–R, from the Formosan Soft Coral Cladiella hirsuta
abstract	New eunicellin-type hirsutalins N–R (1–5), along with two known eunicellins, (6 and 7) were isolated from the soft coral Cladiella hirsuta. The structures of the metabolites were determined by extensive spectroscopic analysis. Cytotoxic activity of compounds 1–7 against the proliferation of a limited panel of cancer cell lines was measured. The in vitro anti-inflammatory activity of compounds 1–7 was evaluated by measuring their ability in suppressing superoxide anion generation and elastase release in fMLP/CB-induced human neutrophils.
abstractGer	New eunicellin-type hirsutalins N–R (1–5), along with two known eunicellins, (6 and 7) were isolated from the soft coral Cladiella hirsuta. The structures of the metabolites were determined by extensive spectroscopic analysis. Cytotoxic activity of compounds 1–7 against the proliferation of a limited panel of cancer cell lines was measured. The in vitro anti-inflammatory activity of compounds 1–7 was evaluated by measuring their ability in suppressing superoxide anion generation and elastase release in fMLP/CB-induced human neutrophils.
abstract_unstemmed	New eunicellin-type hirsutalins N–R (1–5), along with two known eunicellins, (6 and 7) were isolated from the soft coral Cladiella hirsuta. The structures of the metabolites were determined by extensive spectroscopic analysis. Cytotoxic activity of compounds 1–7 against the proliferation of a limited panel of cancer cell lines was measured. The in vitro anti-inflammatory activity of compounds 1–7 was evaluated by measuring their ability in suppressing superoxide anion generation and elastase release in fMLP/CB-induced human neutrophils.
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title_short	Eunicellin-Based Diterpenoids, Hirsutalins N–R, from the Formosan Soft Coral Cladiella hirsuta
url	https://doi.org/10.3390/md12052446 https://doaj.org/article/a6dbdd2a6b7a4b738e4268474de84dcd http://www.mdpi.com/1660-3397/12/5/2446 https://doaj.org/toc/1660-3397
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