Krempfielins N–P, New Anti-Inflammatory Eunicellins from a Taiwanese Soft Coral Cladiella krempfi

Three new eunicellin-type diterpenoids, krempfielins N–P (1–3), were isolated from a Taiwanese soft coral Cladiella krempfi. The structures of the new metabolites were elucidated by extensive spectroscopic analysis and by comparison with spectroscopic data of related known compounds. Compound 3 exh...
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Autor*in:	Yan-Ning Lee [verfasserIn] Chi-Jen Tai [verfasserIn] Tsong-Long Hwang [verfasserIn] Jyh-Horng Sheu [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2014

Schlagwörter:	Cladiella krempfi eunicellin-type diterpenoid anti-inflammatory agent elastase

Übergeordnetes Werk:	In: Marine Drugs - MDPI AG, 2005, 12(2014), 2, Seite 1148-1156
Übergeordnetes Werk:	volume:12 ; year:2014 ; number:2 ; pages:1148-1156

Links:	Link aufrufen Link aufrufen Link aufrufen Journal toc

DOI / URN:	10.3390/md12021148

Katalog-ID:	DOAJ025928635

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language	English
source	In Marine Drugs 12(2014), 2, Seite 1148-1156 volume:12 year:2014 number:2 pages:1148-1156
sourceStr	In Marine Drugs 12(2014), 2, Seite 1148-1156 volume:12 year:2014 number:2 pages:1148-1156
format_phy_str_mv	Article
institution	findex.gbv.de
topic_facet	Cladiella krempfi eunicellin-type diterpenoid anti-inflammatory agent elastase Biology (General)
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container_title	Marine Drugs
authorswithroles_txt_mv	Yan-Ning Lee @@aut@@ Chi-Jen Tai @@aut@@ Tsong-Long Hwang @@aut@@ Jyh-Horng Sheu @@aut@@
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callnumber-first	Q - Science
author	Yan-Ning Lee
spellingShingle	Yan-Ning Lee misc QH301-705.5 misc Cladiella krempfi misc eunicellin-type diterpenoid misc anti-inflammatory agent misc elastase misc Biology (General) Krempfielins N–P, New Anti-Inflammatory Eunicellins from a Taiwanese Soft Coral Cladiella krempfi
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topic_title	QH301-705.5 Krempfielins N–P, New Anti-Inflammatory Eunicellins from a Taiwanese Soft Coral Cladiella krempfi Cladiella krempfi eunicellin-type diterpenoid anti-inflammatory agent elastase
topic	misc QH301-705.5 misc Cladiella krempfi misc eunicellin-type diterpenoid misc anti-inflammatory agent misc elastase misc Biology (General)
topic_unstemmed	misc QH301-705.5 misc Cladiella krempfi misc eunicellin-type diterpenoid misc anti-inflammatory agent misc elastase misc Biology (General)
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title	Krempfielins N–P, New Anti-Inflammatory Eunicellins from a Taiwanese Soft Coral Cladiella krempfi
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title_full	Krempfielins N–P, New Anti-Inflammatory Eunicellins from a Taiwanese Soft Coral Cladiella krempfi
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title_sort	krempfielins n–p, new anti-inflammatory eunicellins from a taiwanese soft coral cladiella krempfi
callnumber	QH301-705.5
title_auth	Krempfielins N–P, New Anti-Inflammatory Eunicellins from a Taiwanese Soft Coral Cladiella krempfi
abstract	Three new eunicellin-type diterpenoids, krempfielins N–P (1–3), were isolated from a Taiwanese soft coral Cladiella krempfi. The structures of the new metabolites were elucidated by extensive spectroscopic analysis and by comparison with spectroscopic data of related known compounds. Compound 3 exhibited activity to inhibit superoxide anion generation. Both 1 and 3, in particular 1, were shown to display significant anti-inflammatory activity by inhibiting the elastase release in FMLP/CB-induced human neutrophils.
abstractGer	Three new eunicellin-type diterpenoids, krempfielins N–P (1–3), were isolated from a Taiwanese soft coral Cladiella krempfi. The structures of the new metabolites were elucidated by extensive spectroscopic analysis and by comparison with spectroscopic data of related known compounds. Compound 3 exhibited activity to inhibit superoxide anion generation. Both 1 and 3, in particular 1, were shown to display significant anti-inflammatory activity by inhibiting the elastase release in FMLP/CB-induced human neutrophils.
abstract_unstemmed	Three new eunicellin-type diterpenoids, krempfielins N–P (1–3), were isolated from a Taiwanese soft coral Cladiella krempfi. The structures of the new metabolites were elucidated by extensive spectroscopic analysis and by comparison with spectroscopic data of related known compounds. Compound 3 exhibited activity to inhibit superoxide anion generation. Both 1 and 3, in particular 1, were shown to display significant anti-inflammatory activity by inhibiting the elastase release in FMLP/CB-induced human neutrophils.
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title_short	Krempfielins N–P, New Anti-Inflammatory Eunicellins from a Taiwanese Soft Coral Cladiella krempfi
url	https://doi.org/10.3390/md12021148 https://doaj.org/article/3a990705a7d8452b80bc5687c819fdf5 http://www.mdpi.com/1660-3397/12/2/1148 https://doaj.org/toc/1660-3397
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up_date	2024-07-03T18:00:01.210Z
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