The effect of low-dose nitroglycerin on oxidative stress in patients with hypertension undergoing laparoscopic gynecological surgery
Objective To evaluate the effect of low-dose nitroglycerin on oxidative stress and apelin-12 levels in hypertension patients undergoing laparoscopic gynecological surgery. Methods Eighty patients with hypertension who underwent laparoscopic total hysterectomy were recruited and divided into the nitr...
Ausführliche Beschreibung
Gespeichert in:
| Autor*in: |
Wu Dan, Yang Shan, Ding Yi, Fan Junbai [verfasserIn] |
|---|
| Format: |
E-Artikel |
|---|---|
| Sprache: |
Chinesisch |
| Erschienen: |
2022 |
|---|
| Schlagwörter: |
|nitroglycerin|laparoscopy|hypertension|oxidative stress|apelin-apj |
|---|
| Übergeordnetes Werk: |
In: Xin yixue - Editorial Office of Journal of New Medicine, 2022, 53(2022), 2, Seite 118-122 |
|---|---|
| Übergeordnetes Werk: |
volume:53 ; year:2022 ; number:2 ; pages:118-122 |
| Links: |
|---|
| DOI / URN: |
10.3969/j.issn.0253-9802.2022.02.009 |
|---|
| Katalog-ID: |
DOAJ026203790 |
|---|
| LEADER | 01000caa a22002652 4500 | ||
|---|---|---|---|
| 001 | DOAJ026203790 | ||
| 003 | DE-627 | ||
| 005 | 20230307095853.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 230226s2022 xx |||||o 00| ||chi c | ||
| 024 | 7 | |a 10.3969/j.issn.0253-9802.2022.02.009 |2 doi | |
| 035 | |a (DE-627)DOAJ026203790 | ||
| 035 | |a (DE-599)DOAJ200b8c456086405d98715df2e1d8e177 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
| 041 | |a chi | ||
| 100 | 0 | |a Wu Dan, Yang Shan, Ding Yi, Fan Junbai |e verfasserin |4 aut | |
| 245 | 1 | 4 | |a The effect of low-dose nitroglycerin on oxidative stress in patients with hypertension undergoing laparoscopic gynecological surgery |
| 264 | 1 | |c 2022 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a Computermedien |b c |2 rdamedia | ||
| 338 | |a Online-Ressource |b cr |2 rdacarrier | ||
| 520 | |a Objective To evaluate the effect of low-dose nitroglycerin on oxidative stress and apelin-12 levels in hypertension patients undergoing laparoscopic gynecological surgery. Methods Eighty patients with hypertension who underwent laparoscopic total hysterectomy were recruited and divided into the nitroglycerin group and control group by random number table method. From the beginning of pneumoperitoneum to the end of operation, patients in the nitroglycerin group were pumped with nitroglycerin （0.10-0.25 μg/（kg·min））, and those in the control group were pumped with the same amount of normal saline. Peripheral elbow venous blood was drawn before operation （T0）, 30 min after pneumoperitoneum （T1）, and 1 h after operation （T2）. The changes of serum levels of Ang-Ⅱ, IL-6, apelin-12, and ST-T were compared between two groups. Results With the increase of pneumoperitoneum time, the serum levels of Ang-Ⅱ and IL-6 were gradually elevated, whereas the serum levels of apelin-12 were steadily decreased within each group. Compared with the control group, the increase of serum levels of Ang-Ⅱ and IL-6 at T1 and T2 were significantly decreased and the decrease of serum level of apelin-12 was also significantly decreased in the nitroglycerin group （all P < 0.05）. The incidence of ST-T abnormality had no statistical significance between two groups （P > 0.05）. Conclusions Low-dose nitroglycerin can alleviate the stress response of patients with hypertension undergoing laparoscopic hysterectomy. Apelin-12 may coordinate with NO to delay the incidence and development of oxidative stress. | ||
| 650 | 4 | |a |nitroglycerin|laparoscopy|hypertension|oxidative stress|apelin-apj | |
| 653 | 0 | |a Medicine | |
| 653 | 0 | |a R | |
| 773 | 0 | 8 | |i In |t Xin yixue |d Editorial Office of Journal of New Medicine, 2022 |g 53(2022), 2, Seite 118-122 |w (DE-627)DOAJ000152676 |x 02539802 |7 nnns |
| 773 | 1 | 8 | |g volume:53 |g year:2022 |g number:2 |g pages:118-122 |
| 856 | 4 | 0 | |u https://doi.org/10.3969/j.issn.0253-9802.2022.02.009 |z kostenfrei |
| 856 | 4 | 0 | |u https://doaj.org/article/200b8c456086405d98715df2e1d8e177 |z kostenfrei |
| 856 | 4 | 0 | |u https://www.xinyixue.cn/fileup/0253-9802/PDF/1646274124556-1653495805.pdf |z kostenfrei |
| 856 | 4 | 2 | |u https://doaj.org/toc/0253-9802 |y Journal toc |z kostenfrei |
| 912 | |a GBV_USEFLAG_A | ||
| 912 | |a SYSFLAG_A | ||
| 912 | |a GBV_DOAJ | ||
| 951 | |a AR | ||
| 952 | |d 53 |j 2022 |e 2 |h 118-122 | ||
| author_variant |
d y s d y f j w dysdyfj dysdyfjw |
|---|---|
| matchkey_str |
article:02539802:2022----::hefcolwoeirgyeiooiaietesnainsihyetninnegiga |
| hierarchy_sort_str |
2022 |
| publishDate |
2022 |
| allfields |
10.3969/j.issn.0253-9802.2022.02.009 doi (DE-627)DOAJ026203790 (DE-599)DOAJ200b8c456086405d98715df2e1d8e177 DE-627 ger DE-627 rakwb chi Wu Dan, Yang Shan, Ding Yi, Fan Junbai verfasserin aut The effect of low-dose nitroglycerin on oxidative stress in patients with hypertension undergoing laparoscopic gynecological surgery 2022 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Objective To evaluate the effect of low-dose nitroglycerin on oxidative stress and apelin-12 levels in hypertension patients undergoing laparoscopic gynecological surgery. Methods Eighty patients with hypertension who underwent laparoscopic total hysterectomy were recruited and divided into the nitroglycerin group and control group by random number table method. From the beginning of pneumoperitoneum to the end of operation, patients in the nitroglycerin group were pumped with nitroglycerin （0.10-0.25 μg/（kg·min））, and those in the control group were pumped with the same amount of normal saline. Peripheral elbow venous blood was drawn before operation （T0）, 30 min after pneumoperitoneum （T1）, and 1 h after operation （T2）. The changes of serum levels of Ang-Ⅱ, IL-6, apelin-12, and ST-T were compared between two groups. Results With the increase of pneumoperitoneum time, the serum levels of Ang-Ⅱ and IL-6 were gradually elevated, whereas the serum levels of apelin-12 were steadily decreased within each group. Compared with the control group, the increase of serum levels of Ang-Ⅱ and IL-6 at T1 and T2 were significantly decreased and the decrease of serum level of apelin-12 was also significantly decreased in the nitroglycerin group （all P < 0.05）. The incidence of ST-T abnormality had no statistical significance between two groups （P > 0.05）. Conclusions Low-dose nitroglycerin can alleviate the stress response of patients with hypertension undergoing laparoscopic hysterectomy. Apelin-12 may coordinate with NO to delay the incidence and development of oxidative stress. |nitroglycerin|laparoscopy|hypertension|oxidative stress|apelin-apj Medicine R In Xin yixue Editorial Office of Journal of New Medicine, 2022 53(2022), 2, Seite 118-122 (DE-627)DOAJ000152676 02539802 nnns volume:53 year:2022 number:2 pages:118-122 https://doi.org/10.3969/j.issn.0253-9802.2022.02.009 kostenfrei https://doaj.org/article/200b8c456086405d98715df2e1d8e177 kostenfrei https://www.xinyixue.cn/fileup/0253-9802/PDF/1646274124556-1653495805.pdf kostenfrei https://doaj.org/toc/0253-9802 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ AR 53 2022 2 118-122 |
| spelling |
10.3969/j.issn.0253-9802.2022.02.009 doi (DE-627)DOAJ026203790 (DE-599)DOAJ200b8c456086405d98715df2e1d8e177 DE-627 ger DE-627 rakwb chi Wu Dan, Yang Shan, Ding Yi, Fan Junbai verfasserin aut The effect of low-dose nitroglycerin on oxidative stress in patients with hypertension undergoing laparoscopic gynecological surgery 2022 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Objective To evaluate the effect of low-dose nitroglycerin on oxidative stress and apelin-12 levels in hypertension patients undergoing laparoscopic gynecological surgery. Methods Eighty patients with hypertension who underwent laparoscopic total hysterectomy were recruited and divided into the nitroglycerin group and control group by random number table method. From the beginning of pneumoperitoneum to the end of operation, patients in the nitroglycerin group were pumped with nitroglycerin （0.10-0.25 μg/（kg·min））, and those in the control group were pumped with the same amount of normal saline. Peripheral elbow venous blood was drawn before operation （T0）, 30 min after pneumoperitoneum （T1）, and 1 h after operation （T2）. The changes of serum levels of Ang-Ⅱ, IL-6, apelin-12, and ST-T were compared between two groups. Results With the increase of pneumoperitoneum time, the serum levels of Ang-Ⅱ and IL-6 were gradually elevated, whereas the serum levels of apelin-12 were steadily decreased within each group. Compared with the control group, the increase of serum levels of Ang-Ⅱ and IL-6 at T1 and T2 were significantly decreased and the decrease of serum level of apelin-12 was also significantly decreased in the nitroglycerin group （all P < 0.05）. The incidence of ST-T abnormality had no statistical significance between two groups （P > 0.05）. Conclusions Low-dose nitroglycerin can alleviate the stress response of patients with hypertension undergoing laparoscopic hysterectomy. Apelin-12 may coordinate with NO to delay the incidence and development of oxidative stress. |nitroglycerin|laparoscopy|hypertension|oxidative stress|apelin-apj Medicine R In Xin yixue Editorial Office of Journal of New Medicine, 2022 53(2022), 2, Seite 118-122 (DE-627)DOAJ000152676 02539802 nnns volume:53 year:2022 number:2 pages:118-122 https://doi.org/10.3969/j.issn.0253-9802.2022.02.009 kostenfrei https://doaj.org/article/200b8c456086405d98715df2e1d8e177 kostenfrei https://www.xinyixue.cn/fileup/0253-9802/PDF/1646274124556-1653495805.pdf kostenfrei https://doaj.org/toc/0253-9802 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ AR 53 2022 2 118-122 |
| allfields_unstemmed |
10.3969/j.issn.0253-9802.2022.02.009 doi (DE-627)DOAJ026203790 (DE-599)DOAJ200b8c456086405d98715df2e1d8e177 DE-627 ger DE-627 rakwb chi Wu Dan, Yang Shan, Ding Yi, Fan Junbai verfasserin aut The effect of low-dose nitroglycerin on oxidative stress in patients with hypertension undergoing laparoscopic gynecological surgery 2022 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Objective To evaluate the effect of low-dose nitroglycerin on oxidative stress and apelin-12 levels in hypertension patients undergoing laparoscopic gynecological surgery. Methods Eighty patients with hypertension who underwent laparoscopic total hysterectomy were recruited and divided into the nitroglycerin group and control group by random number table method. From the beginning of pneumoperitoneum to the end of operation, patients in the nitroglycerin group were pumped with nitroglycerin （0.10-0.25 μg/（kg·min））, and those in the control group were pumped with the same amount of normal saline. Peripheral elbow venous blood was drawn before operation （T0）, 30 min after pneumoperitoneum （T1）, and 1 h after operation （T2）. The changes of serum levels of Ang-Ⅱ, IL-6, apelin-12, and ST-T were compared between two groups. Results With the increase of pneumoperitoneum time, the serum levels of Ang-Ⅱ and IL-6 were gradually elevated, whereas the serum levels of apelin-12 were steadily decreased within each group. Compared with the control group, the increase of serum levels of Ang-Ⅱ and IL-6 at T1 and T2 were significantly decreased and the decrease of serum level of apelin-12 was also significantly decreased in the nitroglycerin group （all P < 0.05）. The incidence of ST-T abnormality had no statistical significance between two groups （P > 0.05）. Conclusions Low-dose nitroglycerin can alleviate the stress response of patients with hypertension undergoing laparoscopic hysterectomy. Apelin-12 may coordinate with NO to delay the incidence and development of oxidative stress. |nitroglycerin|laparoscopy|hypertension|oxidative stress|apelin-apj Medicine R In Xin yixue Editorial Office of Journal of New Medicine, 2022 53(2022), 2, Seite 118-122 (DE-627)DOAJ000152676 02539802 nnns volume:53 year:2022 number:2 pages:118-122 https://doi.org/10.3969/j.issn.0253-9802.2022.02.009 kostenfrei https://doaj.org/article/200b8c456086405d98715df2e1d8e177 kostenfrei https://www.xinyixue.cn/fileup/0253-9802/PDF/1646274124556-1653495805.pdf kostenfrei https://doaj.org/toc/0253-9802 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ AR 53 2022 2 118-122 |
| allfieldsGer |
10.3969/j.issn.0253-9802.2022.02.009 doi (DE-627)DOAJ026203790 (DE-599)DOAJ200b8c456086405d98715df2e1d8e177 DE-627 ger DE-627 rakwb chi Wu Dan, Yang Shan, Ding Yi, Fan Junbai verfasserin aut The effect of low-dose nitroglycerin on oxidative stress in patients with hypertension undergoing laparoscopic gynecological surgery 2022 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Objective To evaluate the effect of low-dose nitroglycerin on oxidative stress and apelin-12 levels in hypertension patients undergoing laparoscopic gynecological surgery. Methods Eighty patients with hypertension who underwent laparoscopic total hysterectomy were recruited and divided into the nitroglycerin group and control group by random number table method. From the beginning of pneumoperitoneum to the end of operation, patients in the nitroglycerin group were pumped with nitroglycerin （0.10-0.25 μg/（kg·min））, and those in the control group were pumped with the same amount of normal saline. Peripheral elbow venous blood was drawn before operation （T0）, 30 min after pneumoperitoneum （T1）, and 1 h after operation （T2）. The changes of serum levels of Ang-Ⅱ, IL-6, apelin-12, and ST-T were compared between two groups. Results With the increase of pneumoperitoneum time, the serum levels of Ang-Ⅱ and IL-6 were gradually elevated, whereas the serum levels of apelin-12 were steadily decreased within each group. Compared with the control group, the increase of serum levels of Ang-Ⅱ and IL-6 at T1 and T2 were significantly decreased and the decrease of serum level of apelin-12 was also significantly decreased in the nitroglycerin group （all P < 0.05）. The incidence of ST-T abnormality had no statistical significance between two groups （P > 0.05）. Conclusions Low-dose nitroglycerin can alleviate the stress response of patients with hypertension undergoing laparoscopic hysterectomy. Apelin-12 may coordinate with NO to delay the incidence and development of oxidative stress. |nitroglycerin|laparoscopy|hypertension|oxidative stress|apelin-apj Medicine R In Xin yixue Editorial Office of Journal of New Medicine, 2022 53(2022), 2, Seite 118-122 (DE-627)DOAJ000152676 02539802 nnns volume:53 year:2022 number:2 pages:118-122 https://doi.org/10.3969/j.issn.0253-9802.2022.02.009 kostenfrei https://doaj.org/article/200b8c456086405d98715df2e1d8e177 kostenfrei https://www.xinyixue.cn/fileup/0253-9802/PDF/1646274124556-1653495805.pdf kostenfrei https://doaj.org/toc/0253-9802 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ AR 53 2022 2 118-122 |
| allfieldsSound |
10.3969/j.issn.0253-9802.2022.02.009 doi (DE-627)DOAJ026203790 (DE-599)DOAJ200b8c456086405d98715df2e1d8e177 DE-627 ger DE-627 rakwb chi Wu Dan, Yang Shan, Ding Yi, Fan Junbai verfasserin aut The effect of low-dose nitroglycerin on oxidative stress in patients with hypertension undergoing laparoscopic gynecological surgery 2022 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Objective To evaluate the effect of low-dose nitroglycerin on oxidative stress and apelin-12 levels in hypertension patients undergoing laparoscopic gynecological surgery. Methods Eighty patients with hypertension who underwent laparoscopic total hysterectomy were recruited and divided into the nitroglycerin group and control group by random number table method. From the beginning of pneumoperitoneum to the end of operation, patients in the nitroglycerin group were pumped with nitroglycerin （0.10-0.25 μg/（kg·min））, and those in the control group were pumped with the same amount of normal saline. Peripheral elbow venous blood was drawn before operation （T0）, 30 min after pneumoperitoneum （T1）, and 1 h after operation （T2）. The changes of serum levels of Ang-Ⅱ, IL-6, apelin-12, and ST-T were compared between two groups. Results With the increase of pneumoperitoneum time, the serum levels of Ang-Ⅱ and IL-6 were gradually elevated, whereas the serum levels of apelin-12 were steadily decreased within each group. Compared with the control group, the increase of serum levels of Ang-Ⅱ and IL-6 at T1 and T2 were significantly decreased and the decrease of serum level of apelin-12 was also significantly decreased in the nitroglycerin group （all P < 0.05）. The incidence of ST-T abnormality had no statistical significance between two groups （P > 0.05）. Conclusions Low-dose nitroglycerin can alleviate the stress response of patients with hypertension undergoing laparoscopic hysterectomy. Apelin-12 may coordinate with NO to delay the incidence and development of oxidative stress. |nitroglycerin|laparoscopy|hypertension|oxidative stress|apelin-apj Medicine R In Xin yixue Editorial Office of Journal of New Medicine, 2022 53(2022), 2, Seite 118-122 (DE-627)DOAJ000152676 02539802 nnns volume:53 year:2022 number:2 pages:118-122 https://doi.org/10.3969/j.issn.0253-9802.2022.02.009 kostenfrei https://doaj.org/article/200b8c456086405d98715df2e1d8e177 kostenfrei https://www.xinyixue.cn/fileup/0253-9802/PDF/1646274124556-1653495805.pdf kostenfrei https://doaj.org/toc/0253-9802 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ AR 53 2022 2 118-122 |
| language |
Chinese |
| source |
In Xin yixue 53(2022), 2, Seite 118-122 volume:53 year:2022 number:2 pages:118-122 |
| sourceStr |
In Xin yixue 53(2022), 2, Seite 118-122 volume:53 year:2022 number:2 pages:118-122 |
| format_phy_str_mv |
Article |
| institution |
findex.gbv.de |
| topic_facet |
|nitroglycerin|laparoscopy|hypertension|oxidative stress|apelin-apj Medicine R |
| isfreeaccess_bool |
true |
| container_title |
Xin yixue |
| authorswithroles_txt_mv |
Wu Dan, Yang Shan, Ding Yi, Fan Junbai @@aut@@ |
| publishDateDaySort_date |
2022-01-01T00:00:00Z |
| hierarchy_top_id |
DOAJ000152676 |
| id |
DOAJ026203790 |
| language_de |
chinesisch |
| fullrecord |
<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000caa a22002652 4500</leader><controlfield tag="001">DOAJ026203790</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20230307095853.0</controlfield><controlfield tag="007">cr uuu---uuuuu</controlfield><controlfield tag="008">230226s2022 xx |||||o 00| ||chi c</controlfield><datafield tag="024" ind1="7" ind2=" "><subfield code="a">10.3969/j.issn.0253-9802.2022.02.009</subfield><subfield code="2">doi</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)DOAJ026203790</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-599)DOAJ200b8c456086405d98715df2e1d8e177</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="041" ind1=" " ind2=" "><subfield code="a">chi</subfield></datafield><datafield tag="100" ind1="0" ind2=" "><subfield code="a">Wu Dan, Yang Shan, Ding Yi, Fan Junbai</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="4"><subfield code="a">The effect of low-dose nitroglycerin on oxidative stress in patients with hypertension undergoing laparoscopic gynecological surgery</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="c">2022</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">Text</subfield><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">Computermedien</subfield><subfield code="b">c</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">Online-Ressource</subfield><subfield code="b">cr</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">Objective To evaluate the effect of low-dose nitroglycerin on oxidative stress and apelin-12 levels in hypertension patients undergoing laparoscopic gynecological surgery. Methods Eighty patients with hypertension who underwent laparoscopic total hysterectomy were recruited and divided into the nitroglycerin group and control group by random number table method. From the beginning of pneumoperitoneum to the end of operation, patients in the nitroglycerin group were pumped with nitroglycerin （0.10-0.25 μg/（kg·min））, and those in the control group were pumped with the same amount of normal saline. Peripheral elbow venous blood was drawn before operation （T0）, 30 min after pneumoperitoneum （T1）, and 1 h after operation （T2）. The changes of serum levels of Ang-Ⅱ, IL-6, apelin-12, and ST-T were compared between two groups. Results With the increase of pneumoperitoneum time, the serum levels of Ang-Ⅱ and IL-6 were gradually elevated, whereas the serum levels of apelin-12 were steadily decreased within each group. Compared with the control group, the increase of serum levels of Ang-Ⅱ and IL-6 at T1 and T2 were significantly decreased and the decrease of serum level of apelin-12 was also significantly decreased in the nitroglycerin group （all P &lt; 0.05）. The incidence of ST-T abnormality had no statistical significance between two groups （P &gt; 0.05）. Conclusions Low-dose nitroglycerin can alleviate the stress response of patients with hypertension undergoing laparoscopic hysterectomy. Apelin-12 may coordinate with NO to delay the incidence and development of oxidative stress.</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">|nitroglycerin|laparoscopy|hypertension|oxidative stress|apelin-apj</subfield></datafield><datafield tag="653" ind1=" " ind2="0"><subfield code="a">Medicine</subfield></datafield><datafield tag="653" ind1=" " ind2="0"><subfield code="a">R</subfield></datafield><datafield tag="773" ind1="0" ind2="8"><subfield code="i">In</subfield><subfield code="t">Xin yixue</subfield><subfield code="d">Editorial Office of Journal of New Medicine, 2022</subfield><subfield code="g">53(2022), 2, Seite 118-122</subfield><subfield code="w">(DE-627)DOAJ000152676</subfield><subfield code="x">02539802</subfield><subfield code="7">nnns</subfield></datafield><datafield tag="773" ind1="1" ind2="8"><subfield code="g">volume:53</subfield><subfield code="g">year:2022</subfield><subfield code="g">number:2</subfield><subfield code="g">pages:118-122</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">https://doi.org/10.3969/j.issn.0253-9802.2022.02.009</subfield><subfield code="z">kostenfrei</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">https://doaj.org/article/200b8c456086405d98715df2e1d8e177</subfield><subfield code="z">kostenfrei</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">https://www.xinyixue.cn/fileup/0253-9802/PDF/1646274124556-1653495805.pdf</subfield><subfield code="z">kostenfrei</subfield></datafield><datafield tag="856" ind1="4" ind2="2"><subfield code="u">https://doaj.org/toc/0253-9802</subfield><subfield code="y">Journal toc</subfield><subfield code="z">kostenfrei</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_USEFLAG_A</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">SYSFLAG_A</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_DOAJ</subfield></datafield><datafield tag="951" ind1=" " ind2=" "><subfield code="a">AR</subfield></datafield><datafield tag="952" ind1=" " ind2=" "><subfield code="d">53</subfield><subfield code="j">2022</subfield><subfield code="e">2</subfield><subfield code="h">118-122</subfield></datafield></record></collection>
|
| author |
Wu Dan, Yang Shan, Ding Yi, Fan Junbai |
| spellingShingle |
Wu Dan, Yang Shan, Ding Yi, Fan Junbai misc |nitroglycerin|laparoscopy|hypertension|oxidative stress|apelin-apj misc Medicine misc R The effect of low-dose nitroglycerin on oxidative stress in patients with hypertension undergoing laparoscopic gynecological surgery |
| authorStr |
Wu Dan, Yang Shan, Ding Yi, Fan Junbai |
| ppnlink_with_tag_str_mv |
@@773@@(DE-627)DOAJ000152676 |
| format |
electronic Article |
| delete_txt_mv |
keep |
| author_role |
aut |
| collection |
DOAJ |
| remote_str |
true |
| illustrated |
Not Illustrated |
| issn |
02539802 |
| topic_title |
The effect of low-dose nitroglycerin on oxidative stress in patients with hypertension undergoing laparoscopic gynecological surgery |nitroglycerin|laparoscopy|hypertension|oxidative stress|apelin-apj |
| topic |
misc |nitroglycerin|laparoscopy|hypertension|oxidative stress|apelin-apj misc Medicine misc R |
| topic_unstemmed |
misc |nitroglycerin|laparoscopy|hypertension|oxidative stress|apelin-apj misc Medicine misc R |
| topic_browse |
misc |nitroglycerin|laparoscopy|hypertension|oxidative stress|apelin-apj misc Medicine misc R |
| format_facet |
Elektronische Aufsätze Aufsätze Elektronische Ressource |
| format_main_str_mv |
Text Zeitschrift/Artikel |
| carriertype_str_mv |
cr |
| hierarchy_parent_title |
Xin yixue |
| hierarchy_parent_id |
DOAJ000152676 |
| hierarchy_top_title |
Xin yixue |
| isfreeaccess_txt |
true |
| familylinks_str_mv |
(DE-627)DOAJ000152676 |
| title |
The effect of low-dose nitroglycerin on oxidative stress in patients with hypertension undergoing laparoscopic gynecological surgery |
| ctrlnum |
(DE-627)DOAJ026203790 (DE-599)DOAJ200b8c456086405d98715df2e1d8e177 |
| title_full |
The effect of low-dose nitroglycerin on oxidative stress in patients with hypertension undergoing laparoscopic gynecological surgery |
| author_sort |
Wu Dan, Yang Shan, Ding Yi, Fan Junbai |
| journal |
Xin yixue |
| journalStr |
Xin yixue |
| lang_code |
chi |
| isOA_bool |
true |
| recordtype |
marc |
| publishDateSort |
2022 |
| contenttype_str_mv |
txt |
| container_start_page |
118 |
| author_browse |
Wu Dan, Yang Shan, Ding Yi, Fan Junbai |
| container_volume |
53 |
| format_se |
Elektronische Aufsätze |
| author-letter |
Wu Dan, Yang Shan, Ding Yi, Fan Junbai |
| doi_str_mv |
10.3969/j.issn.0253-9802.2022.02.009 |
| title_sort |
effect of low-dose nitroglycerin on oxidative stress in patients with hypertension undergoing laparoscopic gynecological surgery |
| title_auth |
The effect of low-dose nitroglycerin on oxidative stress in patients with hypertension undergoing laparoscopic gynecological surgery |
| abstract |
Objective To evaluate the effect of low-dose nitroglycerin on oxidative stress and apelin-12 levels in hypertension patients undergoing laparoscopic gynecological surgery. Methods Eighty patients with hypertension who underwent laparoscopic total hysterectomy were recruited and divided into the nitroglycerin group and control group by random number table method. From the beginning of pneumoperitoneum to the end of operation, patients in the nitroglycerin group were pumped with nitroglycerin （0.10-0.25 μg/（kg·min））, and those in the control group were pumped with the same amount of normal saline. Peripheral elbow venous blood was drawn before operation （T0）, 30 min after pneumoperitoneum （T1）, and 1 h after operation （T2）. The changes of serum levels of Ang-Ⅱ, IL-6, apelin-12, and ST-T were compared between two groups. Results With the increase of pneumoperitoneum time, the serum levels of Ang-Ⅱ and IL-6 were gradually elevated, whereas the serum levels of apelin-12 were steadily decreased within each group. Compared with the control group, the increase of serum levels of Ang-Ⅱ and IL-6 at T1 and T2 were significantly decreased and the decrease of serum level of apelin-12 was also significantly decreased in the nitroglycerin group （all P < 0.05）. The incidence of ST-T abnormality had no statistical significance between two groups （P > 0.05）. Conclusions Low-dose nitroglycerin can alleviate the stress response of patients with hypertension undergoing laparoscopic hysterectomy. Apelin-12 may coordinate with NO to delay the incidence and development of oxidative stress. |
| abstractGer |
Objective To evaluate the effect of low-dose nitroglycerin on oxidative stress and apelin-12 levels in hypertension patients undergoing laparoscopic gynecological surgery. Methods Eighty patients with hypertension who underwent laparoscopic total hysterectomy were recruited and divided into the nitroglycerin group and control group by random number table method. From the beginning of pneumoperitoneum to the end of operation, patients in the nitroglycerin group were pumped with nitroglycerin （0.10-0.25 μg/（kg·min））, and those in the control group were pumped with the same amount of normal saline. Peripheral elbow venous blood was drawn before operation （T0）, 30 min after pneumoperitoneum （T1）, and 1 h after operation （T2）. The changes of serum levels of Ang-Ⅱ, IL-6, apelin-12, and ST-T were compared between two groups. Results With the increase of pneumoperitoneum time, the serum levels of Ang-Ⅱ and IL-6 were gradually elevated, whereas the serum levels of apelin-12 were steadily decreased within each group. Compared with the control group, the increase of serum levels of Ang-Ⅱ and IL-6 at T1 and T2 were significantly decreased and the decrease of serum level of apelin-12 was also significantly decreased in the nitroglycerin group （all P < 0.05）. The incidence of ST-T abnormality had no statistical significance between two groups （P > 0.05）. Conclusions Low-dose nitroglycerin can alleviate the stress response of patients with hypertension undergoing laparoscopic hysterectomy. Apelin-12 may coordinate with NO to delay the incidence and development of oxidative stress. |
| abstract_unstemmed |
Objective To evaluate the effect of low-dose nitroglycerin on oxidative stress and apelin-12 levels in hypertension patients undergoing laparoscopic gynecological surgery. Methods Eighty patients with hypertension who underwent laparoscopic total hysterectomy were recruited and divided into the nitroglycerin group and control group by random number table method. From the beginning of pneumoperitoneum to the end of operation, patients in the nitroglycerin group were pumped with nitroglycerin （0.10-0.25 μg/（kg·min））, and those in the control group were pumped with the same amount of normal saline. Peripheral elbow venous blood was drawn before operation （T0）, 30 min after pneumoperitoneum （T1）, and 1 h after operation （T2）. The changes of serum levels of Ang-Ⅱ, IL-6, apelin-12, and ST-T were compared between two groups. Results With the increase of pneumoperitoneum time, the serum levels of Ang-Ⅱ and IL-6 were gradually elevated, whereas the serum levels of apelin-12 were steadily decreased within each group. Compared with the control group, the increase of serum levels of Ang-Ⅱ and IL-6 at T1 and T2 were significantly decreased and the decrease of serum level of apelin-12 was also significantly decreased in the nitroglycerin group （all P < 0.05）. The incidence of ST-T abnormality had no statistical significance between two groups （P > 0.05）. Conclusions Low-dose nitroglycerin can alleviate the stress response of patients with hypertension undergoing laparoscopic hysterectomy. Apelin-12 may coordinate with NO to delay the incidence and development of oxidative stress. |
| collection_details |
GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ |
| container_issue |
2 |
| title_short |
The effect of low-dose nitroglycerin on oxidative stress in patients with hypertension undergoing laparoscopic gynecological surgery |
| url |
https://doi.org/10.3969/j.issn.0253-9802.2022.02.009 https://doaj.org/article/200b8c456086405d98715df2e1d8e177 https://www.xinyixue.cn/fileup/0253-9802/PDF/1646274124556-1653495805.pdf https://doaj.org/toc/0253-9802 |
| remote_bool |
true |
| ppnlink |
DOAJ000152676 |
| mediatype_str_mv |
c |
| isOA_txt |
true |
| hochschulschrift_bool |
false |
| doi_str |
10.3969/j.issn.0253-9802.2022.02.009 |
| up_date |
2024-07-03T19:38:12.860Z |
| _version_ |
1803587936966410240 |
| fullrecord_marcxml |
<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000caa a22002652 4500</leader><controlfield tag="001">DOAJ026203790</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20230307095853.0</controlfield><controlfield tag="007">cr uuu---uuuuu</controlfield><controlfield tag="008">230226s2022 xx |||||o 00| ||chi c</controlfield><datafield tag="024" ind1="7" ind2=" "><subfield code="a">10.3969/j.issn.0253-9802.2022.02.009</subfield><subfield code="2">doi</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)DOAJ026203790</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-599)DOAJ200b8c456086405d98715df2e1d8e177</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="041" ind1=" " ind2=" "><subfield code="a">chi</subfield></datafield><datafield tag="100" ind1="0" ind2=" "><subfield code="a">Wu Dan, Yang Shan, Ding Yi, Fan Junbai</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="4"><subfield code="a">The effect of low-dose nitroglycerin on oxidative stress in patients with hypertension undergoing laparoscopic gynecological surgery</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="c">2022</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">Text</subfield><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">Computermedien</subfield><subfield code="b">c</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">Online-Ressource</subfield><subfield code="b">cr</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">Objective To evaluate the effect of low-dose nitroglycerin on oxidative stress and apelin-12 levels in hypertension patients undergoing laparoscopic gynecological surgery. Methods Eighty patients with hypertension who underwent laparoscopic total hysterectomy were recruited and divided into the nitroglycerin group and control group by random number table method. From the beginning of pneumoperitoneum to the end of operation, patients in the nitroglycerin group were pumped with nitroglycerin （0.10-0.25 μg/（kg·min））, and those in the control group were pumped with the same amount of normal saline. Peripheral elbow venous blood was drawn before operation （T0）, 30 min after pneumoperitoneum （T1）, and 1 h after operation （T2）. The changes of serum levels of Ang-Ⅱ, IL-6, apelin-12, and ST-T were compared between two groups. Results With the increase of pneumoperitoneum time, the serum levels of Ang-Ⅱ and IL-6 were gradually elevated, whereas the serum levels of apelin-12 were steadily decreased within each group. Compared with the control group, the increase of serum levels of Ang-Ⅱ and IL-6 at T1 and T2 were significantly decreased and the decrease of serum level of apelin-12 was also significantly decreased in the nitroglycerin group （all P &lt; 0.05）. The incidence of ST-T abnormality had no statistical significance between two groups （P &gt; 0.05）. Conclusions Low-dose nitroglycerin can alleviate the stress response of patients with hypertension undergoing laparoscopic hysterectomy. Apelin-12 may coordinate with NO to delay the incidence and development of oxidative stress.</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">|nitroglycerin|laparoscopy|hypertension|oxidative stress|apelin-apj</subfield></datafield><datafield tag="653" ind1=" " ind2="0"><subfield code="a">Medicine</subfield></datafield><datafield tag="653" ind1=" " ind2="0"><subfield code="a">R</subfield></datafield><datafield tag="773" ind1="0" ind2="8"><subfield code="i">In</subfield><subfield code="t">Xin yixue</subfield><subfield code="d">Editorial Office of Journal of New Medicine, 2022</subfield><subfield code="g">53(2022), 2, Seite 118-122</subfield><subfield code="w">(DE-627)DOAJ000152676</subfield><subfield code="x">02539802</subfield><subfield code="7">nnns</subfield></datafield><datafield tag="773" ind1="1" ind2="8"><subfield code="g">volume:53</subfield><subfield code="g">year:2022</subfield><subfield code="g">number:2</subfield><subfield code="g">pages:118-122</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">https://doi.org/10.3969/j.issn.0253-9802.2022.02.009</subfield><subfield code="z">kostenfrei</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">https://doaj.org/article/200b8c456086405d98715df2e1d8e177</subfield><subfield code="z">kostenfrei</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">https://www.xinyixue.cn/fileup/0253-9802/PDF/1646274124556-1653495805.pdf</subfield><subfield code="z">kostenfrei</subfield></datafield><datafield tag="856" ind1="4" ind2="2"><subfield code="u">https://doaj.org/toc/0253-9802</subfield><subfield code="y">Journal toc</subfield><subfield code="z">kostenfrei</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_USEFLAG_A</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">SYSFLAG_A</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_DOAJ</subfield></datafield><datafield tag="951" ind1=" " ind2=" "><subfield code="a">AR</subfield></datafield><datafield tag="952" ind1=" " ind2=" "><subfield code="d">53</subfield><subfield code="j">2022</subfield><subfield code="e">2</subfield><subfield code="h">118-122</subfield></datafield></record></collection>
|
| score |
7.4004107 |