Intestinal Permeability Assays: a Review

Aim. A literature review of intestinal permeability assessment techniques.Key points. The intestinal barrier is a functional entity separating the intestinal lumen and internal body, and intestinal permeability is a measure of the barrier functionality. The intestinal barrier integrity and permeabil...
Ausführliche Beschreibung

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Autor*in:	A. A. Iakupova [verfasserIn] S. R. Abdulkhakov [verfasserIn] R. K. Zalyalov [verfasserIn] A. G. Safin [verfasserIn] R. A. Abdulkhakov [verfasserIn]

Format:	E-Artikel
Sprache:	Russisch

Erschienen:	2021

Schlagwörter:	intestinal permeability intestinal barrier sugar test lipopolysaccharide tight junctions

Übergeordnetes Werk:	In: Российский журнал гастроэнтерологии, гепатологии, колопроктологии - Gastro LLC, 2020, 31(2021), 1, Seite 20-30
Übergeordnetes Werk:	volume:31 ; year:2021 ; number:1 ; pages:20-30

Links:	Link aufrufen Link aufrufen Link aufrufen Journal toc Journal toc

DOI / URN:	10.22416/1382-4376-2021-31-1-20-30

Katalog-ID:	DOAJ026246007

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allfieldsSound	10.22416/1382-4376-2021-31-1-20-30 doi (DE-627)DOAJ026246007 (DE-599)DOAJ71d8e5a1586a4d9488cba31c40191507 DE-627 ger DE-627 rakwb rus RC799-869 A. A. Iakupova verfasserin aut Intestinal Permeability Assays: a Review 2021 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Aim. A literature review of intestinal permeability assessment techniques.Key points. The intestinal barrier is a functional entity separating the intestinal lumen and internal body, and intestinal permeability is a measure of the barrier functionality. The intestinal barrier integrity and permeability assays differ by the application setting (in vivo or ex vivo), subject (human or animal), marker molecules used to assess permeability (ions, various size carbohydrates, macromolecules, antigens, bacterial products and bacteria), biomaterial for the marker concentration assays (peripheral blood, portal venous blood, urine, stool). Despite a great variety of methods for assessing intestinal permeability, their clinical application requires further studies due to a lack of standardisation, the complexity of selected techniques and occasional limited reliability of results.Conclusion. Further investigation and improvement of intestinal permeability assays is required. The assay and result standardisation will facilitate practice in functional and organic intestinal diseases, as well as allergies, diabetes mellitus, non-alcoholic fatty liver disease and some other illnesses. intestinal permeability intestinal barrier sugar test lipopolysaccharide tight junctions Diseases of the digestive system. Gastroenterology S. R. Abdulkhakov verfasserin aut R. K. Zalyalov verfasserin aut A. G. Safin verfasserin aut R. A. Abdulkhakov verfasserin aut In Российский журнал гастроэнтерологии, гепатологии, колопроктологии Gastro LLC, 2020 31(2021), 1, Seite 20-30 (DE-627)1698164203 26586673 nnns volume:31 year:2021 number:1 pages:20-30 https://doi.org/10.22416/1382-4376-2021-31-1-20-30 kostenfrei https://doaj.org/article/71d8e5a1586a4d9488cba31c40191507 kostenfrei https://www.gastro-j.ru/jour/article/view/525 kostenfrei https://doaj.org/toc/1382-4376 Journal toc kostenfrei https://doaj.org/toc/2658-6673 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 31 2021 1 20-30
language	Russian
source	In Российский журнал гастроэнтерологии, гепатологии, колопроктологии 31(2021), 1, Seite 20-30 volume:31 year:2021 number:1 pages:20-30
sourceStr	In Российский журнал гастроэнтерологии, гепатологии, колопроктологии 31(2021), 1, Seite 20-30 volume:31 year:2021 number:1 pages:20-30
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institution	findex.gbv.de
topic_facet	intestinal permeability intestinal barrier sugar test lipopolysaccharide tight junctions Diseases of the digestive system. Gastroenterology
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callnumber-first	R - Medicine
author	A. A. Iakupova
spellingShingle	A. A. Iakupova misc RC799-869 misc intestinal permeability misc intestinal barrier misc sugar test misc lipopolysaccharide misc tight junctions misc Diseases of the digestive system. Gastroenterology Intestinal Permeability Assays: a Review
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topic_title	RC799-869 Intestinal Permeability Assays: a Review intestinal permeability intestinal barrier sugar test lipopolysaccharide tight junctions
topic	misc RC799-869 misc intestinal permeability misc intestinal barrier misc sugar test misc lipopolysaccharide misc tight junctions misc Diseases of the digestive system. Gastroenterology
topic_unstemmed	misc RC799-869 misc intestinal permeability misc intestinal barrier misc sugar test misc lipopolysaccharide misc tight junctions misc Diseases of the digestive system. Gastroenterology
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title	Intestinal Permeability Assays: a Review
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title_sort	intestinal permeability assays: a review
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title_auth	Intestinal Permeability Assays: a Review
abstract	Aim. A literature review of intestinal permeability assessment techniques.Key points. The intestinal barrier is a functional entity separating the intestinal lumen and internal body, and intestinal permeability is a measure of the barrier functionality. The intestinal barrier integrity and permeability assays differ by the application setting (in vivo or ex vivo), subject (human or animal), marker molecules used to assess permeability (ions, various size carbohydrates, macromolecules, antigens, bacterial products and bacteria), biomaterial for the marker concentration assays (peripheral blood, portal venous blood, urine, stool). Despite a great variety of methods for assessing intestinal permeability, their clinical application requires further studies due to a lack of standardisation, the complexity of selected techniques and occasional limited reliability of results.Conclusion. Further investigation and improvement of intestinal permeability assays is required. The assay and result standardisation will facilitate practice in functional and organic intestinal diseases, as well as allergies, diabetes mellitus, non-alcoholic fatty liver disease and some other illnesses.
abstractGer	Aim. A literature review of intestinal permeability assessment techniques.Key points. The intestinal barrier is a functional entity separating the intestinal lumen and internal body, and intestinal permeability is a measure of the barrier functionality. The intestinal barrier integrity and permeability assays differ by the application setting (in vivo or ex vivo), subject (human or animal), marker molecules used to assess permeability (ions, various size carbohydrates, macromolecules, antigens, bacterial products and bacteria), biomaterial for the marker concentration assays (peripheral blood, portal venous blood, urine, stool). Despite a great variety of methods for assessing intestinal permeability, their clinical application requires further studies due to a lack of standardisation, the complexity of selected techniques and occasional limited reliability of results.Conclusion. Further investigation and improvement of intestinal permeability assays is required. The assay and result standardisation will facilitate practice in functional and organic intestinal diseases, as well as allergies, diabetes mellitus, non-alcoholic fatty liver disease and some other illnesses.
abstract_unstemmed	Aim. A literature review of intestinal permeability assessment techniques.Key points. The intestinal barrier is a functional entity separating the intestinal lumen and internal body, and intestinal permeability is a measure of the barrier functionality. The intestinal barrier integrity and permeability assays differ by the application setting (in vivo or ex vivo), subject (human or animal), marker molecules used to assess permeability (ions, various size carbohydrates, macromolecules, antigens, bacterial products and bacteria), biomaterial for the marker concentration assays (peripheral blood, portal venous blood, urine, stool). Despite a great variety of methods for assessing intestinal permeability, their clinical application requires further studies due to a lack of standardisation, the complexity of selected techniques and occasional limited reliability of results.Conclusion. Further investigation and improvement of intestinal permeability assays is required. The assay and result standardisation will facilitate practice in functional and organic intestinal diseases, as well as allergies, diabetes mellitus, non-alcoholic fatty liver disease and some other illnesses.
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title_short	Intestinal Permeability Assays: a Review
url	https://doi.org/10.22416/1382-4376-2021-31-1-20-30 https://doaj.org/article/71d8e5a1586a4d9488cba31c40191507 https://www.gastro-j.ru/jour/article/view/525 https://doaj.org/toc/1382-4376 https://doaj.org/toc/2658-6673
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author2	S. R. Abdulkhakov R. K. Zalyalov A. G. Safin R. A. Abdulkhakov
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