Management of recurrent postoperative fungal endophthalmitis
Aim: To report the management of recurrent postoperative fungal endophthalmitis (POFE) after failed pars plana vitrectomy (PPV) and antifungal therapy. Settings and Design: Tertiary Care Referral Centre in North India. Retrospective, single institution, interventional case-series. Materials and Meth...
Ausführliche Beschreibung
Autor*in: |
Anand Vinekar [verfasserIn] Mangat R Dogra [verfasserIn] Kavitha Avadhani [verfasserIn] Vishali Gupta [verfasserIn] Amod Gupta [verfasserIn] Arunaloke Chakrabarti [verfasserIn] |
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Format: |
E-Artikel |
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Sprache: |
Englisch |
Erschienen: |
2014 |
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Schlagwörter: |
multiple disabilities and visual impairment human corneal endothelial precursor cells |
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Übergeordnetes Werk: |
In: Indian Journal of Ophthalmology - Wolters Kluwer Medknow Publications, 2005, 62(2014), 2, Seite 136-140 |
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Übergeordnetes Werk: |
volume:62 ; year:2014 ; number:2 ; pages:136-140 |
Links: |
Link aufrufen |
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DOI / URN: |
10.4103/0301-4738.128588 |
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Katalog-ID: |
DOAJ026269236 |
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520 | |a Aim: To report the management of recurrent postoperative fungal endophthalmitis (POFE) after failed pars plana vitrectomy (PPV) and antifungal therapy. Settings and Design: Tertiary Care Referral Centre in North India. Retrospective, single institution, interventional case-series. Materials and Methods: Six patients with microbiologically proven recurrent post-operative fungal endophthalmitis refractory to conventional management were included. The final recurrence was managed with intraocular lens (IOL) explantation and re-PPV. Main outcome measures included preserved globe anatomy, visual acuity and retinal status. ′Anatomical success′ was defined as preserved anatomy of the globe, and absence of signs of inflammation. ′Functional success′ was defined as an attached retina and a best corrected visual acuity of better than 20/400. Results: Of the six cases of POFE, five were culture positive [Aspergillus flavus (1), Aspergillus fumigatus (2), Candida albicans (1) and Candida glabrata (1)] and one was smear positive for yeast. All recurred (mean recurrences, 4) despite a mean of 2.17 PPVs and intravitreal amphotericin B. No recurrences were observed after IOL explantation with re - PPV (median follow-up, 37 months). Pre-study defined criteria for successful ′anatomical′ and ′functional′ outcomes were achieved in 83.3% and 50% respectively. Conclusion: This report highlights the effective role of combined IOL explantation with PPV in managing recurrent POFE. | ||
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10.4103/0301-4738.128588 doi (DE-627)DOAJ026269236 (DE-599)DOAJ70cf865971134889a6bf79a14cdf6fc2 DE-627 ger DE-627 rakwb eng RE1-994 Anand Vinekar verfasserin aut Management of recurrent postoperative fungal endophthalmitis 2014 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Aim: To report the management of recurrent postoperative fungal endophthalmitis (POFE) after failed pars plana vitrectomy (PPV) and antifungal therapy. Settings and Design: Tertiary Care Referral Centre in North India. Retrospective, single institution, interventional case-series. Materials and Methods: Six patients with microbiologically proven recurrent post-operative fungal endophthalmitis refractory to conventional management were included. The final recurrence was managed with intraocular lens (IOL) explantation and re-PPV. Main outcome measures included preserved globe anatomy, visual acuity and retinal status. ′Anatomical success′ was defined as preserved anatomy of the globe, and absence of signs of inflammation. ′Functional success′ was defined as an attached retina and a best corrected visual acuity of better than 20/400. Results: Of the six cases of POFE, five were culture positive [Aspergillus flavus (1), Aspergillus fumigatus (2), Candida albicans (1) and Candida glabrata (1)] and one was smear positive for yeast. All recurred (mean recurrences, 4) despite a mean of 2.17 PPVs and intravitreal amphotericin B. No recurrences were observed after IOL explantation with re - PPV (median follow-up, 37 months). Pre-study defined criteria for successful ′anatomical′ and ′functional′ outcomes were achieved in 83.3% and 50% respectively. Conclusion: This report highlights the effective role of combined IOL explantation with PPV in managing recurrent POFE. Blindness cataract eye lens risk factors treatment of cataract Low vision care multiple disabilities and visual impairment reading performance Accommodation presbyopia supraciliary segment implants Amblyopia citicoline patching Corneal endothelium human corneal endothelial precursor cells in vitro expansion sphere forming assay thermo-reversible gelation polymer transportation Endophthalmitis explantation fungal intraocular lens postoperative recurrent Ophthalmology Mangat R Dogra verfasserin aut Kavitha Avadhani verfasserin aut Vishali Gupta verfasserin aut Amod Gupta verfasserin aut Arunaloke Chakrabarti verfasserin aut In Indian Journal of Ophthalmology Wolters Kluwer Medknow Publications, 2005 62(2014), 2, Seite 136-140 (DE-627)485243563 (DE-600)2185999-1 19983689 nnns volume:62 year:2014 number:2 pages:136-140 https://doi.org/10.4103/0301-4738.128588 kostenfrei https://doaj.org/article/70cf865971134889a6bf79a14cdf6fc2 kostenfrei http://www.ijo.in/article.asp?issn=0301-4738;year=2014;volume=62;issue=2;spage=136;epage=140;aulast=Vinekar kostenfrei https://doaj.org/toc/0301-4738 Journal toc kostenfrei https://doaj.org/toc/1998-3689 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2031 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2061 GBV_ILN_2111 GBV_ILN_2113 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 62 2014 2 136-140 |
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10.4103/0301-4738.128588 doi (DE-627)DOAJ026269236 (DE-599)DOAJ70cf865971134889a6bf79a14cdf6fc2 DE-627 ger DE-627 rakwb eng RE1-994 Anand Vinekar verfasserin aut Management of recurrent postoperative fungal endophthalmitis 2014 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Aim: To report the management of recurrent postoperative fungal endophthalmitis (POFE) after failed pars plana vitrectomy (PPV) and antifungal therapy. Settings and Design: Tertiary Care Referral Centre in North India. Retrospective, single institution, interventional case-series. Materials and Methods: Six patients with microbiologically proven recurrent post-operative fungal endophthalmitis refractory to conventional management were included. The final recurrence was managed with intraocular lens (IOL) explantation and re-PPV. Main outcome measures included preserved globe anatomy, visual acuity and retinal status. ′Anatomical success′ was defined as preserved anatomy of the globe, and absence of signs of inflammation. ′Functional success′ was defined as an attached retina and a best corrected visual acuity of better than 20/400. Results: Of the six cases of POFE, five were culture positive [Aspergillus flavus (1), Aspergillus fumigatus (2), Candida albicans (1) and Candida glabrata (1)] and one was smear positive for yeast. All recurred (mean recurrences, 4) despite a mean of 2.17 PPVs and intravitreal amphotericin B. No recurrences were observed after IOL explantation with re - PPV (median follow-up, 37 months). Pre-study defined criteria for successful ′anatomical′ and ′functional′ outcomes were achieved in 83.3% and 50% respectively. Conclusion: This report highlights the effective role of combined IOL explantation with PPV in managing recurrent POFE. Blindness cataract eye lens risk factors treatment of cataract Low vision care multiple disabilities and visual impairment reading performance Accommodation presbyopia supraciliary segment implants Amblyopia citicoline patching Corneal endothelium human corneal endothelial precursor cells in vitro expansion sphere forming assay thermo-reversible gelation polymer transportation Endophthalmitis explantation fungal intraocular lens postoperative recurrent Ophthalmology Mangat R Dogra verfasserin aut Kavitha Avadhani verfasserin aut Vishali Gupta verfasserin aut Amod Gupta verfasserin aut Arunaloke Chakrabarti verfasserin aut In Indian Journal of Ophthalmology Wolters Kluwer Medknow Publications, 2005 62(2014), 2, Seite 136-140 (DE-627)485243563 (DE-600)2185999-1 19983689 nnns volume:62 year:2014 number:2 pages:136-140 https://doi.org/10.4103/0301-4738.128588 kostenfrei https://doaj.org/article/70cf865971134889a6bf79a14cdf6fc2 kostenfrei http://www.ijo.in/article.asp?issn=0301-4738;year=2014;volume=62;issue=2;spage=136;epage=140;aulast=Vinekar kostenfrei https://doaj.org/toc/0301-4738 Journal toc kostenfrei https://doaj.org/toc/1998-3689 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2031 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2061 GBV_ILN_2111 GBV_ILN_2113 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 62 2014 2 136-140 |
allfields_unstemmed |
10.4103/0301-4738.128588 doi (DE-627)DOAJ026269236 (DE-599)DOAJ70cf865971134889a6bf79a14cdf6fc2 DE-627 ger DE-627 rakwb eng RE1-994 Anand Vinekar verfasserin aut Management of recurrent postoperative fungal endophthalmitis 2014 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Aim: To report the management of recurrent postoperative fungal endophthalmitis (POFE) after failed pars plana vitrectomy (PPV) and antifungal therapy. Settings and Design: Tertiary Care Referral Centre in North India. Retrospective, single institution, interventional case-series. Materials and Methods: Six patients with microbiologically proven recurrent post-operative fungal endophthalmitis refractory to conventional management were included. The final recurrence was managed with intraocular lens (IOL) explantation and re-PPV. Main outcome measures included preserved globe anatomy, visual acuity and retinal status. ′Anatomical success′ was defined as preserved anatomy of the globe, and absence of signs of inflammation. ′Functional success′ was defined as an attached retina and a best corrected visual acuity of better than 20/400. Results: Of the six cases of POFE, five were culture positive [Aspergillus flavus (1), Aspergillus fumigatus (2), Candida albicans (1) and Candida glabrata (1)] and one was smear positive for yeast. All recurred (mean recurrences, 4) despite a mean of 2.17 PPVs and intravitreal amphotericin B. No recurrences were observed after IOL explantation with re - PPV (median follow-up, 37 months). Pre-study defined criteria for successful ′anatomical′ and ′functional′ outcomes were achieved in 83.3% and 50% respectively. Conclusion: This report highlights the effective role of combined IOL explantation with PPV in managing recurrent POFE. Blindness cataract eye lens risk factors treatment of cataract Low vision care multiple disabilities and visual impairment reading performance Accommodation presbyopia supraciliary segment implants Amblyopia citicoline patching Corneal endothelium human corneal endothelial precursor cells in vitro expansion sphere forming assay thermo-reversible gelation polymer transportation Endophthalmitis explantation fungal intraocular lens postoperative recurrent Ophthalmology Mangat R Dogra verfasserin aut Kavitha Avadhani verfasserin aut Vishali Gupta verfasserin aut Amod Gupta verfasserin aut Arunaloke Chakrabarti verfasserin aut In Indian Journal of Ophthalmology Wolters Kluwer Medknow Publications, 2005 62(2014), 2, Seite 136-140 (DE-627)485243563 (DE-600)2185999-1 19983689 nnns volume:62 year:2014 number:2 pages:136-140 https://doi.org/10.4103/0301-4738.128588 kostenfrei https://doaj.org/article/70cf865971134889a6bf79a14cdf6fc2 kostenfrei http://www.ijo.in/article.asp?issn=0301-4738;year=2014;volume=62;issue=2;spage=136;epage=140;aulast=Vinekar kostenfrei https://doaj.org/toc/0301-4738 Journal toc kostenfrei https://doaj.org/toc/1998-3689 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2031 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2061 GBV_ILN_2111 GBV_ILN_2113 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 62 2014 2 136-140 |
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10.4103/0301-4738.128588 doi (DE-627)DOAJ026269236 (DE-599)DOAJ70cf865971134889a6bf79a14cdf6fc2 DE-627 ger DE-627 rakwb eng RE1-994 Anand Vinekar verfasserin aut Management of recurrent postoperative fungal endophthalmitis 2014 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Aim: To report the management of recurrent postoperative fungal endophthalmitis (POFE) after failed pars plana vitrectomy (PPV) and antifungal therapy. Settings and Design: Tertiary Care Referral Centre in North India. Retrospective, single institution, interventional case-series. Materials and Methods: Six patients with microbiologically proven recurrent post-operative fungal endophthalmitis refractory to conventional management were included. The final recurrence was managed with intraocular lens (IOL) explantation and re-PPV. Main outcome measures included preserved globe anatomy, visual acuity and retinal status. ′Anatomical success′ was defined as preserved anatomy of the globe, and absence of signs of inflammation. ′Functional success′ was defined as an attached retina and a best corrected visual acuity of better than 20/400. Results: Of the six cases of POFE, five were culture positive [Aspergillus flavus (1), Aspergillus fumigatus (2), Candida albicans (1) and Candida glabrata (1)] and one was smear positive for yeast. All recurred (mean recurrences, 4) despite a mean of 2.17 PPVs and intravitreal amphotericin B. No recurrences were observed after IOL explantation with re - PPV (median follow-up, 37 months). Pre-study defined criteria for successful ′anatomical′ and ′functional′ outcomes were achieved in 83.3% and 50% respectively. Conclusion: This report highlights the effective role of combined IOL explantation with PPV in managing recurrent POFE. Blindness cataract eye lens risk factors treatment of cataract Low vision care multiple disabilities and visual impairment reading performance Accommodation presbyopia supraciliary segment implants Amblyopia citicoline patching Corneal endothelium human corneal endothelial precursor cells in vitro expansion sphere forming assay thermo-reversible gelation polymer transportation Endophthalmitis explantation fungal intraocular lens postoperative recurrent Ophthalmology Mangat R Dogra verfasserin aut Kavitha Avadhani verfasserin aut Vishali Gupta verfasserin aut Amod Gupta verfasserin aut Arunaloke Chakrabarti verfasserin aut In Indian Journal of Ophthalmology Wolters Kluwer Medknow Publications, 2005 62(2014), 2, Seite 136-140 (DE-627)485243563 (DE-600)2185999-1 19983689 nnns volume:62 year:2014 number:2 pages:136-140 https://doi.org/10.4103/0301-4738.128588 kostenfrei https://doaj.org/article/70cf865971134889a6bf79a14cdf6fc2 kostenfrei http://www.ijo.in/article.asp?issn=0301-4738;year=2014;volume=62;issue=2;spage=136;epage=140;aulast=Vinekar kostenfrei https://doaj.org/toc/0301-4738 Journal toc kostenfrei https://doaj.org/toc/1998-3689 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2031 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2061 GBV_ILN_2111 GBV_ILN_2113 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 62 2014 2 136-140 |
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10.4103/0301-4738.128588 doi (DE-627)DOAJ026269236 (DE-599)DOAJ70cf865971134889a6bf79a14cdf6fc2 DE-627 ger DE-627 rakwb eng RE1-994 Anand Vinekar verfasserin aut Management of recurrent postoperative fungal endophthalmitis 2014 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Aim: To report the management of recurrent postoperative fungal endophthalmitis (POFE) after failed pars plana vitrectomy (PPV) and antifungal therapy. Settings and Design: Tertiary Care Referral Centre in North India. Retrospective, single institution, interventional case-series. Materials and Methods: Six patients with microbiologically proven recurrent post-operative fungal endophthalmitis refractory to conventional management were included. The final recurrence was managed with intraocular lens (IOL) explantation and re-PPV. Main outcome measures included preserved globe anatomy, visual acuity and retinal status. ′Anatomical success′ was defined as preserved anatomy of the globe, and absence of signs of inflammation. ′Functional success′ was defined as an attached retina and a best corrected visual acuity of better than 20/400. Results: Of the six cases of POFE, five were culture positive [Aspergillus flavus (1), Aspergillus fumigatus (2), Candida albicans (1) and Candida glabrata (1)] and one was smear positive for yeast. All recurred (mean recurrences, 4) despite a mean of 2.17 PPVs and intravitreal amphotericin B. No recurrences were observed after IOL explantation with re - PPV (median follow-up, 37 months). Pre-study defined criteria for successful ′anatomical′ and ′functional′ outcomes were achieved in 83.3% and 50% respectively. Conclusion: This report highlights the effective role of combined IOL explantation with PPV in managing recurrent POFE. Blindness cataract eye lens risk factors treatment of cataract Low vision care multiple disabilities and visual impairment reading performance Accommodation presbyopia supraciliary segment implants Amblyopia citicoline patching Corneal endothelium human corneal endothelial precursor cells in vitro expansion sphere forming assay thermo-reversible gelation polymer transportation Endophthalmitis explantation fungal intraocular lens postoperative recurrent Ophthalmology Mangat R Dogra verfasserin aut Kavitha Avadhani verfasserin aut Vishali Gupta verfasserin aut Amod Gupta verfasserin aut Arunaloke Chakrabarti verfasserin aut In Indian Journal of Ophthalmology Wolters Kluwer Medknow Publications, 2005 62(2014), 2, Seite 136-140 (DE-627)485243563 (DE-600)2185999-1 19983689 nnns volume:62 year:2014 number:2 pages:136-140 https://doi.org/10.4103/0301-4738.128588 kostenfrei https://doaj.org/article/70cf865971134889a6bf79a14cdf6fc2 kostenfrei http://www.ijo.in/article.asp?issn=0301-4738;year=2014;volume=62;issue=2;spage=136;epage=140;aulast=Vinekar kostenfrei https://doaj.org/toc/0301-4738 Journal toc kostenfrei https://doaj.org/toc/1998-3689 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2031 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2061 GBV_ILN_2111 GBV_ILN_2113 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 62 2014 2 136-140 |
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RE1-994 Management of recurrent postoperative fungal endophthalmitis Blindness cataract eye lens risk factors treatment of cataract Low vision care multiple disabilities and visual impairment reading performance Accommodation presbyopia supraciliary segment implants Amblyopia citicoline patching Corneal endothelium human corneal endothelial precursor cells in vitro expansion sphere forming assay thermo-reversible gelation polymer transportation Endophthalmitis explantation fungal intraocular lens postoperative recurrent |
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Management of recurrent postoperative fungal endophthalmitis |
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Anand Vinekar Mangat R Dogra Kavitha Avadhani Vishali Gupta Amod Gupta Arunaloke Chakrabarti |
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Management of recurrent postoperative fungal endophthalmitis |
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Aim: To report the management of recurrent postoperative fungal endophthalmitis (POFE) after failed pars plana vitrectomy (PPV) and antifungal therapy. Settings and Design: Tertiary Care Referral Centre in North India. Retrospective, single institution, interventional case-series. Materials and Methods: Six patients with microbiologically proven recurrent post-operative fungal endophthalmitis refractory to conventional management were included. The final recurrence was managed with intraocular lens (IOL) explantation and re-PPV. Main outcome measures included preserved globe anatomy, visual acuity and retinal status. ′Anatomical success′ was defined as preserved anatomy of the globe, and absence of signs of inflammation. ′Functional success′ was defined as an attached retina and a best corrected visual acuity of better than 20/400. Results: Of the six cases of POFE, five were culture positive [Aspergillus flavus (1), Aspergillus fumigatus (2), Candida albicans (1) and Candida glabrata (1)] and one was smear positive for yeast. All recurred (mean recurrences, 4) despite a mean of 2.17 PPVs and intravitreal amphotericin B. No recurrences were observed after IOL explantation with re - PPV (median follow-up, 37 months). Pre-study defined criteria for successful ′anatomical′ and ′functional′ outcomes were achieved in 83.3% and 50% respectively. Conclusion: This report highlights the effective role of combined IOL explantation with PPV in managing recurrent POFE. |
abstractGer |
Aim: To report the management of recurrent postoperative fungal endophthalmitis (POFE) after failed pars plana vitrectomy (PPV) and antifungal therapy. Settings and Design: Tertiary Care Referral Centre in North India. Retrospective, single institution, interventional case-series. Materials and Methods: Six patients with microbiologically proven recurrent post-operative fungal endophthalmitis refractory to conventional management were included. The final recurrence was managed with intraocular lens (IOL) explantation and re-PPV. Main outcome measures included preserved globe anatomy, visual acuity and retinal status. ′Anatomical success′ was defined as preserved anatomy of the globe, and absence of signs of inflammation. ′Functional success′ was defined as an attached retina and a best corrected visual acuity of better than 20/400. Results: Of the six cases of POFE, five were culture positive [Aspergillus flavus (1), Aspergillus fumigatus (2), Candida albicans (1) and Candida glabrata (1)] and one was smear positive for yeast. All recurred (mean recurrences, 4) despite a mean of 2.17 PPVs and intravitreal amphotericin B. No recurrences were observed after IOL explantation with re - PPV (median follow-up, 37 months). Pre-study defined criteria for successful ′anatomical′ and ′functional′ outcomes were achieved in 83.3% and 50% respectively. Conclusion: This report highlights the effective role of combined IOL explantation with PPV in managing recurrent POFE. |
abstract_unstemmed |
Aim: To report the management of recurrent postoperative fungal endophthalmitis (POFE) after failed pars plana vitrectomy (PPV) and antifungal therapy. Settings and Design: Tertiary Care Referral Centre in North India. Retrospective, single institution, interventional case-series. Materials and Methods: Six patients with microbiologically proven recurrent post-operative fungal endophthalmitis refractory to conventional management were included. The final recurrence was managed with intraocular lens (IOL) explantation and re-PPV. Main outcome measures included preserved globe anatomy, visual acuity and retinal status. ′Anatomical success′ was defined as preserved anatomy of the globe, and absence of signs of inflammation. ′Functional success′ was defined as an attached retina and a best corrected visual acuity of better than 20/400. Results: Of the six cases of POFE, five were culture positive [Aspergillus flavus (1), Aspergillus fumigatus (2), Candida albicans (1) and Candida glabrata (1)] and one was smear positive for yeast. All recurred (mean recurrences, 4) despite a mean of 2.17 PPVs and intravitreal amphotericin B. No recurrences were observed after IOL explantation with re - PPV (median follow-up, 37 months). Pre-study defined criteria for successful ′anatomical′ and ′functional′ outcomes were achieved in 83.3% and 50% respectively. Conclusion: This report highlights the effective role of combined IOL explantation with PPV in managing recurrent POFE. |
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