Management of recurrent postoperative fungal endophthalmitis

Aim: To report the management of recurrent postoperative fungal endophthalmitis (POFE) after failed pars plana vitrectomy (PPV) and antifungal therapy. Settings and Design: Tertiary Care Referral Centre in North India. Retrospective, single institution, interventional case-series. Materials and Meth...
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Autor*in:	Anand Vinekar [verfasserIn] Mangat R Dogra [verfasserIn] Kavitha Avadhani [verfasserIn] Vishali Gupta [verfasserIn] Amod Gupta [verfasserIn] Arunaloke Chakrabarti [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2014

Schlagwörter:	Blindness cataract eye lens risk factors treatment of cataract Low vision care multiple disabilities and visual impairment reading performance Accommodation presbyopia supraciliary segment implants Amblyopia citicoline patching Corneal endothelium human corneal endothelial precursor cells in vitro expansion sphere forming assay thermo-reversible gelation polymer transportation Endophthalmitis explantation fungal intraocular lens postoperative recurrent

Übergeordnetes Werk:	In: Indian Journal of Ophthalmology - Wolters Kluwer Medknow Publications, 2005, 62(2014), 2, Seite 136-140
Übergeordnetes Werk:	volume:62 ; year:2014 ; number:2 ; pages:136-140

Links:	Link aufrufen Link aufrufen Link aufrufen Journal toc Journal toc

DOI / URN:	10.4103/0301-4738.128588

Katalog-ID:	DOAJ026269236

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520			\|a Aim: To report the management of recurrent postoperative fungal endophthalmitis (POFE) after failed pars plana vitrectomy (PPV) and antifungal therapy. Settings and Design: Tertiary Care Referral Centre in North India. Retrospective, single institution, interventional case-series. Materials and Methods: Six patients with microbiologically proven recurrent post-operative fungal endophthalmitis refractory to conventional management were included. The final recurrence was managed with intraocular lens (IOL) explantation and re-PPV. Main outcome measures included preserved globe anatomy, visual acuity and retinal status. ′Anatomical success′ was defined as preserved anatomy of the globe, and absence of signs of inflammation. ′Functional success′ was defined as an attached retina and a best corrected visual acuity of better than 20/400. Results: Of the six cases of POFE, five were culture positive [Aspergillus flavus (1), Aspergillus fumigatus (2), Candida albicans (1) and Candida glabrata (1)] and one was smear positive for yeast. All recurred (mean recurrences, 4) despite a mean of 2.17 PPVs and intravitreal amphotericin B. No recurrences were observed after IOL explantation with re - PPV (median follow-up, 37 months). Pre-study defined criteria for successful ′anatomical′ and ′functional′ outcomes were achieved in 83.3% and 50% respectively. Conclusion: This report highlights the effective role of combined IOL explantation with PPV in managing recurrent POFE.
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650		4	\|a Endophthalmitis
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700	0		\|a Amod Gupta \|e verfasserin \|4 aut
700	0		\|a Arunaloke Chakrabarti \|e verfasserin \|4 aut
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allfields	10.4103/0301-4738.128588 doi (DE-627)DOAJ026269236 (DE-599)DOAJ70cf865971134889a6bf79a14cdf6fc2 DE-627 ger DE-627 rakwb eng RE1-994 Anand Vinekar verfasserin aut Management of recurrent postoperative fungal endophthalmitis 2014 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Aim: To report the management of recurrent postoperative fungal endophthalmitis (POFE) after failed pars plana vitrectomy (PPV) and antifungal therapy. Settings and Design: Tertiary Care Referral Centre in North India. Retrospective, single institution, interventional case-series. Materials and Methods: Six patients with microbiologically proven recurrent post-operative fungal endophthalmitis refractory to conventional management were included. The final recurrence was managed with intraocular lens (IOL) explantation and re-PPV. Main outcome measures included preserved globe anatomy, visual acuity and retinal status. ′Anatomical success′ was defined as preserved anatomy of the globe, and absence of signs of inflammation. ′Functional success′ was defined as an attached retina and a best corrected visual acuity of better than 20/400. Results: Of the six cases of POFE, five were culture positive [Aspergillus flavus (1), Aspergillus fumigatus (2), Candida albicans (1) and Candida glabrata (1)] and one was smear positive for yeast. All recurred (mean recurrences, 4) despite a mean of 2.17 PPVs and intravitreal amphotericin B. No recurrences were observed after IOL explantation with re - PPV (median follow-up, 37 months). Pre-study defined criteria for successful ′anatomical′ and ′functional′ outcomes were achieved in 83.3% and 50% respectively. Conclusion: This report highlights the effective role of combined IOL explantation with PPV in managing recurrent POFE. Blindness cataract eye lens risk factors treatment of cataract Low vision care multiple disabilities and visual impairment reading performance Accommodation presbyopia supraciliary segment implants Amblyopia citicoline patching Corneal endothelium human corneal endothelial precursor cells in vitro expansion sphere forming assay thermo-reversible gelation polymer transportation Endophthalmitis explantation fungal intraocular lens postoperative recurrent Ophthalmology Mangat R Dogra verfasserin aut Kavitha Avadhani verfasserin aut Vishali Gupta verfasserin aut Amod Gupta verfasserin aut Arunaloke Chakrabarti verfasserin aut In Indian Journal of Ophthalmology Wolters Kluwer Medknow Publications, 2005 62(2014), 2, Seite 136-140 (DE-627)485243563 (DE-600)2185999-1 19983689 nnns volume:62 year:2014 number:2 pages:136-140 https://doi.org/10.4103/0301-4738.128588 kostenfrei https://doaj.org/article/70cf865971134889a6bf79a14cdf6fc2 kostenfrei http://www.ijo.in/article.asp?issn=0301-4738;year=2014;volume=62;issue=2;spage=136;epage=140;aulast=Vinekar kostenfrei https://doaj.org/toc/0301-4738 Journal toc kostenfrei https://doaj.org/toc/1998-3689 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2031 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2061 GBV_ILN_2111 GBV_ILN_2113 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 62 2014 2 136-140
spelling	10.4103/0301-4738.128588 doi (DE-627)DOAJ026269236 (DE-599)DOAJ70cf865971134889a6bf79a14cdf6fc2 DE-627 ger DE-627 rakwb eng RE1-994 Anand Vinekar verfasserin aut Management of recurrent postoperative fungal endophthalmitis 2014 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Aim: To report the management of recurrent postoperative fungal endophthalmitis (POFE) after failed pars plana vitrectomy (PPV) and antifungal therapy. Settings and Design: Tertiary Care Referral Centre in North India. Retrospective, single institution, interventional case-series. Materials and Methods: Six patients with microbiologically proven recurrent post-operative fungal endophthalmitis refractory to conventional management were included. The final recurrence was managed with intraocular lens (IOL) explantation and re-PPV. Main outcome measures included preserved globe anatomy, visual acuity and retinal status. ′Anatomical success′ was defined as preserved anatomy of the globe, and absence of signs of inflammation. ′Functional success′ was defined as an attached retina and a best corrected visual acuity of better than 20/400. Results: Of the six cases of POFE, five were culture positive [Aspergillus flavus (1), Aspergillus fumigatus (2), Candida albicans (1) and Candida glabrata (1)] and one was smear positive for yeast. All recurred (mean recurrences, 4) despite a mean of 2.17 PPVs and intravitreal amphotericin B. No recurrences were observed after IOL explantation with re - PPV (median follow-up, 37 months). Pre-study defined criteria for successful ′anatomical′ and ′functional′ outcomes were achieved in 83.3% and 50% respectively. Conclusion: This report highlights the effective role of combined IOL explantation with PPV in managing recurrent POFE. Blindness cataract eye lens risk factors treatment of cataract Low vision care multiple disabilities and visual impairment reading performance Accommodation presbyopia supraciliary segment implants Amblyopia citicoline patching Corneal endothelium human corneal endothelial precursor cells in vitro expansion sphere forming assay thermo-reversible gelation polymer transportation Endophthalmitis explantation fungal intraocular lens postoperative recurrent Ophthalmology Mangat R Dogra verfasserin aut Kavitha Avadhani verfasserin aut Vishali Gupta verfasserin aut Amod Gupta verfasserin aut Arunaloke Chakrabarti verfasserin aut In Indian Journal of Ophthalmology Wolters Kluwer Medknow Publications, 2005 62(2014), 2, Seite 136-140 (DE-627)485243563 (DE-600)2185999-1 19983689 nnns volume:62 year:2014 number:2 pages:136-140 https://doi.org/10.4103/0301-4738.128588 kostenfrei https://doaj.org/article/70cf865971134889a6bf79a14cdf6fc2 kostenfrei http://www.ijo.in/article.asp?issn=0301-4738;year=2014;volume=62;issue=2;spage=136;epage=140;aulast=Vinekar kostenfrei https://doaj.org/toc/0301-4738 Journal toc kostenfrei https://doaj.org/toc/1998-3689 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2031 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2061 GBV_ILN_2111 GBV_ILN_2113 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 62 2014 2 136-140
allfields_unstemmed	10.4103/0301-4738.128588 doi (DE-627)DOAJ026269236 (DE-599)DOAJ70cf865971134889a6bf79a14cdf6fc2 DE-627 ger DE-627 rakwb eng RE1-994 Anand Vinekar verfasserin aut Management of recurrent postoperative fungal endophthalmitis 2014 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Aim: To report the management of recurrent postoperative fungal endophthalmitis (POFE) after failed pars plana vitrectomy (PPV) and antifungal therapy. Settings and Design: Tertiary Care Referral Centre in North India. Retrospective, single institution, interventional case-series. Materials and Methods: Six patients with microbiologically proven recurrent post-operative fungal endophthalmitis refractory to conventional management were included. The final recurrence was managed with intraocular lens (IOL) explantation and re-PPV. Main outcome measures included preserved globe anatomy, visual acuity and retinal status. ′Anatomical success′ was defined as preserved anatomy of the globe, and absence of signs of inflammation. ′Functional success′ was defined as an attached retina and a best corrected visual acuity of better than 20/400. Results: Of the six cases of POFE, five were culture positive [Aspergillus flavus (1), Aspergillus fumigatus (2), Candida albicans (1) and Candida glabrata (1)] and one was smear positive for yeast. All recurred (mean recurrences, 4) despite a mean of 2.17 PPVs and intravitreal amphotericin B. No recurrences were observed after IOL explantation with re - PPV (median follow-up, 37 months). Pre-study defined criteria for successful ′anatomical′ and ′functional′ outcomes were achieved in 83.3% and 50% respectively. Conclusion: This report highlights the effective role of combined IOL explantation with PPV in managing recurrent POFE. Blindness cataract eye lens risk factors treatment of cataract Low vision care multiple disabilities and visual impairment reading performance Accommodation presbyopia supraciliary segment implants Amblyopia citicoline patching Corneal endothelium human corneal endothelial precursor cells in vitro expansion sphere forming assay thermo-reversible gelation polymer transportation Endophthalmitis explantation fungal intraocular lens postoperative recurrent Ophthalmology Mangat R Dogra verfasserin aut Kavitha Avadhani verfasserin aut Vishali Gupta verfasserin aut Amod Gupta verfasserin aut Arunaloke Chakrabarti verfasserin aut In Indian Journal of Ophthalmology Wolters Kluwer Medknow Publications, 2005 62(2014), 2, Seite 136-140 (DE-627)485243563 (DE-600)2185999-1 19983689 nnns volume:62 year:2014 number:2 pages:136-140 https://doi.org/10.4103/0301-4738.128588 kostenfrei https://doaj.org/article/70cf865971134889a6bf79a14cdf6fc2 kostenfrei http://www.ijo.in/article.asp?issn=0301-4738;year=2014;volume=62;issue=2;spage=136;epage=140;aulast=Vinekar kostenfrei https://doaj.org/toc/0301-4738 Journal toc kostenfrei https://doaj.org/toc/1998-3689 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2031 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2061 GBV_ILN_2111 GBV_ILN_2113 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 62 2014 2 136-140
allfieldsGer	10.4103/0301-4738.128588 doi (DE-627)DOAJ026269236 (DE-599)DOAJ70cf865971134889a6bf79a14cdf6fc2 DE-627 ger DE-627 rakwb eng RE1-994 Anand Vinekar verfasserin aut Management of recurrent postoperative fungal endophthalmitis 2014 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Aim: To report the management of recurrent postoperative fungal endophthalmitis (POFE) after failed pars plana vitrectomy (PPV) and antifungal therapy. Settings and Design: Tertiary Care Referral Centre in North India. Retrospective, single institution, interventional case-series. Materials and Methods: Six patients with microbiologically proven recurrent post-operative fungal endophthalmitis refractory to conventional management were included. The final recurrence was managed with intraocular lens (IOL) explantation and re-PPV. Main outcome measures included preserved globe anatomy, visual acuity and retinal status. ′Anatomical success′ was defined as preserved anatomy of the globe, and absence of signs of inflammation. ′Functional success′ was defined as an attached retina and a best corrected visual acuity of better than 20/400. Results: Of the six cases of POFE, five were culture positive [Aspergillus flavus (1), Aspergillus fumigatus (2), Candida albicans (1) and Candida glabrata (1)] and one was smear positive for yeast. All recurred (mean recurrences, 4) despite a mean of 2.17 PPVs and intravitreal amphotericin B. No recurrences were observed after IOL explantation with re - PPV (median follow-up, 37 months). Pre-study defined criteria for successful ′anatomical′ and ′functional′ outcomes were achieved in 83.3% and 50% respectively. Conclusion: This report highlights the effective role of combined IOL explantation with PPV in managing recurrent POFE. Blindness cataract eye lens risk factors treatment of cataract Low vision care multiple disabilities and visual impairment reading performance Accommodation presbyopia supraciliary segment implants Amblyopia citicoline patching Corneal endothelium human corneal endothelial precursor cells in vitro expansion sphere forming assay thermo-reversible gelation polymer transportation Endophthalmitis explantation fungal intraocular lens postoperative recurrent Ophthalmology Mangat R Dogra verfasserin aut Kavitha Avadhani verfasserin aut Vishali Gupta verfasserin aut Amod Gupta verfasserin aut Arunaloke Chakrabarti verfasserin aut In Indian Journal of Ophthalmology Wolters Kluwer Medknow Publications, 2005 62(2014), 2, Seite 136-140 (DE-627)485243563 (DE-600)2185999-1 19983689 nnns volume:62 year:2014 number:2 pages:136-140 https://doi.org/10.4103/0301-4738.128588 kostenfrei https://doaj.org/article/70cf865971134889a6bf79a14cdf6fc2 kostenfrei http://www.ijo.in/article.asp?issn=0301-4738;year=2014;volume=62;issue=2;spage=136;epage=140;aulast=Vinekar kostenfrei https://doaj.org/toc/0301-4738 Journal toc kostenfrei https://doaj.org/toc/1998-3689 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2031 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2061 GBV_ILN_2111 GBV_ILN_2113 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 62 2014 2 136-140
allfieldsSound	10.4103/0301-4738.128588 doi (DE-627)DOAJ026269236 (DE-599)DOAJ70cf865971134889a6bf79a14cdf6fc2 DE-627 ger DE-627 rakwb eng RE1-994 Anand Vinekar verfasserin aut Management of recurrent postoperative fungal endophthalmitis 2014 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Aim: To report the management of recurrent postoperative fungal endophthalmitis (POFE) after failed pars plana vitrectomy (PPV) and antifungal therapy. Settings and Design: Tertiary Care Referral Centre in North India. Retrospective, single institution, interventional case-series. Materials and Methods: Six patients with microbiologically proven recurrent post-operative fungal endophthalmitis refractory to conventional management were included. The final recurrence was managed with intraocular lens (IOL) explantation and re-PPV. Main outcome measures included preserved globe anatomy, visual acuity and retinal status. ′Anatomical success′ was defined as preserved anatomy of the globe, and absence of signs of inflammation. ′Functional success′ was defined as an attached retina and a best corrected visual acuity of better than 20/400. Results: Of the six cases of POFE, five were culture positive [Aspergillus flavus (1), Aspergillus fumigatus (2), Candida albicans (1) and Candida glabrata (1)] and one was smear positive for yeast. All recurred (mean recurrences, 4) despite a mean of 2.17 PPVs and intravitreal amphotericin B. No recurrences were observed after IOL explantation with re - PPV (median follow-up, 37 months). Pre-study defined criteria for successful ′anatomical′ and ′functional′ outcomes were achieved in 83.3% and 50% respectively. Conclusion: This report highlights the effective role of combined IOL explantation with PPV in managing recurrent POFE. Blindness cataract eye lens risk factors treatment of cataract Low vision care multiple disabilities and visual impairment reading performance Accommodation presbyopia supraciliary segment implants Amblyopia citicoline patching Corneal endothelium human corneal endothelial precursor cells in vitro expansion sphere forming assay thermo-reversible gelation polymer transportation Endophthalmitis explantation fungal intraocular lens postoperative recurrent Ophthalmology Mangat R Dogra verfasserin aut Kavitha Avadhani verfasserin aut Vishali Gupta verfasserin aut Amod Gupta verfasserin aut Arunaloke Chakrabarti verfasserin aut In Indian Journal of Ophthalmology Wolters Kluwer Medknow Publications, 2005 62(2014), 2, Seite 136-140 (DE-627)485243563 (DE-600)2185999-1 19983689 nnns volume:62 year:2014 number:2 pages:136-140 https://doi.org/10.4103/0301-4738.128588 kostenfrei https://doaj.org/article/70cf865971134889a6bf79a14cdf6fc2 kostenfrei http://www.ijo.in/article.asp?issn=0301-4738;year=2014;volume=62;issue=2;spage=136;epage=140;aulast=Vinekar kostenfrei https://doaj.org/toc/0301-4738 Journal toc kostenfrei https://doaj.org/toc/1998-3689 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2031 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2061 GBV_ILN_2111 GBV_ILN_2113 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 62 2014 2 136-140
language	English
source	In Indian Journal of Ophthalmology 62(2014), 2, Seite 136-140 volume:62 year:2014 number:2 pages:136-140
sourceStr	In Indian Journal of Ophthalmology 62(2014), 2, Seite 136-140 volume:62 year:2014 number:2 pages:136-140
format_phy_str_mv	Article
institution	findex.gbv.de
topic_facet	Blindness cataract eye lens risk factors treatment of cataract Low vision care multiple disabilities and visual impairment reading performance Accommodation presbyopia supraciliary segment implants Amblyopia citicoline patching Corneal endothelium human corneal endothelial precursor cells in vitro expansion sphere forming assay thermo-reversible gelation polymer transportation Endophthalmitis explantation fungal intraocular lens postoperative recurrent Ophthalmology
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container_title	Indian Journal of Ophthalmology
authorswithroles_txt_mv	Anand Vinekar @@aut@@ Mangat R Dogra @@aut@@ Kavitha Avadhani @@aut@@ Vishali Gupta @@aut@@ Amod Gupta @@aut@@ Arunaloke Chakrabarti @@aut@@
publishDateDaySort_date	2014-01-01T00:00:00Z
hierarchy_top_id	485243563
id	DOAJ026269236
language_de	englisch
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callnumber-first	R - Medicine
author	Anand Vinekar
spellingShingle	Anand Vinekar misc RE1-994 misc Blindness misc cataract misc eye lens misc risk factors misc treatment of cataract misc Low vision care misc multiple disabilities and visual impairment misc reading performance misc Accommodation misc presbyopia misc supraciliary segment implants misc Amblyopia misc citicoline misc patching misc Corneal endothelium misc human corneal endothelial precursor cells misc in vitro expansion misc sphere forming assay misc thermo-reversible gelation polymer misc transportation misc Endophthalmitis misc explantation misc fungal misc intraocular lens misc postoperative misc recurrent misc Ophthalmology Management of recurrent postoperative fungal endophthalmitis
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topic_title	RE1-994 Management of recurrent postoperative fungal endophthalmitis Blindness cataract eye lens risk factors treatment of cataract Low vision care multiple disabilities and visual impairment reading performance Accommodation presbyopia supraciliary segment implants Amblyopia citicoline patching Corneal endothelium human corneal endothelial precursor cells in vitro expansion sphere forming assay thermo-reversible gelation polymer transportation Endophthalmitis explantation fungal intraocular lens postoperative recurrent
topic	misc RE1-994 misc Blindness misc cataract misc eye lens misc risk factors misc treatment of cataract misc Low vision care misc multiple disabilities and visual impairment misc reading performance misc Accommodation misc presbyopia misc supraciliary segment implants misc Amblyopia misc citicoline misc patching misc Corneal endothelium misc human corneal endothelial precursor cells misc in vitro expansion misc sphere forming assay misc thermo-reversible gelation polymer misc transportation misc Endophthalmitis misc explantation misc fungal misc intraocular lens misc postoperative misc recurrent misc Ophthalmology
topic_unstemmed	misc RE1-994 misc Blindness misc cataract misc eye lens misc risk factors misc treatment of cataract misc Low vision care misc multiple disabilities and visual impairment misc reading performance misc Accommodation misc presbyopia misc supraciliary segment implants misc Amblyopia misc citicoline misc patching misc Corneal endothelium misc human corneal endothelial precursor cells misc in vitro expansion misc sphere forming assay misc thermo-reversible gelation polymer misc transportation misc Endophthalmitis misc explantation misc fungal misc intraocular lens misc postoperative misc recurrent misc Ophthalmology
topic_browse	misc RE1-994 misc Blindness misc cataract misc eye lens misc risk factors misc treatment of cataract misc Low vision care misc multiple disabilities and visual impairment misc reading performance misc Accommodation misc presbyopia misc supraciliary segment implants misc Amblyopia misc citicoline misc patching misc Corneal endothelium misc human corneal endothelial precursor cells misc in vitro expansion misc sphere forming assay misc thermo-reversible gelation polymer misc transportation misc Endophthalmitis misc explantation misc fungal misc intraocular lens misc postoperative misc recurrent misc Ophthalmology
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title	Management of recurrent postoperative fungal endophthalmitis
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title_full	Management of recurrent postoperative fungal endophthalmitis
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author_browse	Anand Vinekar Mangat R Dogra Kavitha Avadhani Vishali Gupta Amod Gupta Arunaloke Chakrabarti
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title_sort	management of recurrent postoperative fungal endophthalmitis
callnumber	RE1-994
title_auth	Management of recurrent postoperative fungal endophthalmitis
abstract	Aim: To report the management of recurrent postoperative fungal endophthalmitis (POFE) after failed pars plana vitrectomy (PPV) and antifungal therapy. Settings and Design: Tertiary Care Referral Centre in North India. Retrospective, single institution, interventional case-series. Materials and Methods: Six patients with microbiologically proven recurrent post-operative fungal endophthalmitis refractory to conventional management were included. The final recurrence was managed with intraocular lens (IOL) explantation and re-PPV. Main outcome measures included preserved globe anatomy, visual acuity and retinal status. ′Anatomical success′ was defined as preserved anatomy of the globe, and absence of signs of inflammation. ′Functional success′ was defined as an attached retina and a best corrected visual acuity of better than 20/400. Results: Of the six cases of POFE, five were culture positive [Aspergillus flavus (1), Aspergillus fumigatus (2), Candida albicans (1) and Candida glabrata (1)] and one was smear positive for yeast. All recurred (mean recurrences, 4) despite a mean of 2.17 PPVs and intravitreal amphotericin B. No recurrences were observed after IOL explantation with re - PPV (median follow-up, 37 months). Pre-study defined criteria for successful ′anatomical′ and ′functional′ outcomes were achieved in 83.3% and 50% respectively. Conclusion: This report highlights the effective role of combined IOL explantation with PPV in managing recurrent POFE.
abstractGer	Aim: To report the management of recurrent postoperative fungal endophthalmitis (POFE) after failed pars plana vitrectomy (PPV) and antifungal therapy. Settings and Design: Tertiary Care Referral Centre in North India. Retrospective, single institution, interventional case-series. Materials and Methods: Six patients with microbiologically proven recurrent post-operative fungal endophthalmitis refractory to conventional management were included. The final recurrence was managed with intraocular lens (IOL) explantation and re-PPV. Main outcome measures included preserved globe anatomy, visual acuity and retinal status. ′Anatomical success′ was defined as preserved anatomy of the globe, and absence of signs of inflammation. ′Functional success′ was defined as an attached retina and a best corrected visual acuity of better than 20/400. Results: Of the six cases of POFE, five were culture positive [Aspergillus flavus (1), Aspergillus fumigatus (2), Candida albicans (1) and Candida glabrata (1)] and one was smear positive for yeast. All recurred (mean recurrences, 4) despite a mean of 2.17 PPVs and intravitreal amphotericin B. No recurrences were observed after IOL explantation with re - PPV (median follow-up, 37 months). Pre-study defined criteria for successful ′anatomical′ and ′functional′ outcomes were achieved in 83.3% and 50% respectively. Conclusion: This report highlights the effective role of combined IOL explantation with PPV in managing recurrent POFE.
abstract_unstemmed	Aim: To report the management of recurrent postoperative fungal endophthalmitis (POFE) after failed pars plana vitrectomy (PPV) and antifungal therapy. Settings and Design: Tertiary Care Referral Centre in North India. Retrospective, single institution, interventional case-series. Materials and Methods: Six patients with microbiologically proven recurrent post-operative fungal endophthalmitis refractory to conventional management were included. The final recurrence was managed with intraocular lens (IOL) explantation and re-PPV. Main outcome measures included preserved globe anatomy, visual acuity and retinal status. ′Anatomical success′ was defined as preserved anatomy of the globe, and absence of signs of inflammation. ′Functional success′ was defined as an attached retina and a best corrected visual acuity of better than 20/400. Results: Of the six cases of POFE, five were culture positive [Aspergillus flavus (1), Aspergillus fumigatus (2), Candida albicans (1) and Candida glabrata (1)] and one was smear positive for yeast. All recurred (mean recurrences, 4) despite a mean of 2.17 PPVs and intravitreal amphotericin B. No recurrences were observed after IOL explantation with re - PPV (median follow-up, 37 months). Pre-study defined criteria for successful ′anatomical′ and ′functional′ outcomes were achieved in 83.3% and 50% respectively. Conclusion: This report highlights the effective role of combined IOL explantation with PPV in managing recurrent POFE.
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title_short	Management of recurrent postoperative fungal endophthalmitis
url	https://doi.org/10.4103/0301-4738.128588 https://doaj.org/article/70cf865971134889a6bf79a14cdf6fc2 http://www.ijo.in/article.asp?issn=0301-4738;year=2014;volume=62;issue=2;spage=136;epage=140;aulast=Vinekar https://doaj.org/toc/0301-4738 https://doaj.org/toc/1998-3689
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Settings and Design: Tertiary Care Referral Centre in North India. Retrospective, single institution, interventional case-series. Materials and Methods: Six patients with microbiologically proven recurrent post-operative fungal endophthalmitis refractory to conventional management were included. The final recurrence was managed with intraocular lens (IOL) explantation and re-PPV. Main outcome measures included preserved globe anatomy, visual acuity and retinal status. ′Anatomical success′ was defined as preserved anatomy of the globe, and absence of signs of inflammation. ′Functional success′ was defined as an attached retina and a best corrected visual acuity of better than 20/400. Results: Of the six cases of POFE, five were culture positive [Aspergillus flavus (1), Aspergillus fumigatus (2), Candida albicans (1) and Candida glabrata (1)] and one was smear positive for yeast. All recurred (mean recurrences, 4) despite a mean of 2.17 PPVs and intravitreal amphotericin B. No recurrences were observed after IOL explantation with re - PPV (median follow-up, 37 months). Pre-study defined criteria for successful ′anatomical′ and ′functional′ outcomes were achieved in 83.3% and 50% respectively. 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Management of recurrent postoperative fungal endophthalmitis

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