Ocular melanoma and mammary mucinous carcinoma in an African lion

<p<Abstract</p< <p<Background</p< <p<Reports of neoplasms in <it<Panthera</it< species are increasing, but they are still an uncommon cause of disease and death in captive wild felids. The presence of two or more primary tumor in large felids is rarely repor...
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Gespeichert in:

Autor*in:	Cagnini Didier Q [verfasserIn] Salgado Breno S [verfasserIn] Linardi Juliana L [verfasserIn] Grandi Fabrizio [verfasserIn] Rocha Rafael M [verfasserIn] Rocha Noeme S [verfasserIn] Teixeira Carlos R [verfasserIn] Del Piero Fabio [verfasserIn] Sequeira Julio L [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2012

Schlagwörter:	Ocular neoplasms Mammary gland Melanocytic neoplasms Peribiliary cysts

Übergeordnetes Werk:	In: BMC Veterinary Research - BMC, 2005, 8(2012), 1, p 176
Übergeordnetes Werk:	volume:8 ; year:2012 ; number:1, p 176

Links:	Link aufrufen Link aufrufen Link aufrufen Journal toc

DOI / URN:	10.1186/1746-6148-8-176

Katalog-ID:	DOAJ026465892

Internformat


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allfields	10.1186/1746-6148-8-176 doi (DE-627)DOAJ026465892 (DE-599)DOAJ3968f1cef97544649ba3416873b99fa9 DE-627 ger DE-627 rakwb eng SF600-1100 Cagnini Didier Q verfasserin aut Ocular melanoma and mammary mucinous carcinoma in an African lion 2012 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier <p<Abstract</p< <p<Background</p< <p<Reports of neoplasms in <it<Panthera</it< species are increasing, but they are still an uncommon cause of disease and death in captive wild felids. The presence of two or more primary tumor in large felids is rarely reported, and there are no documented cases of ocular melanoma and mammary mucinous carcinoma in African lions.</p< <p<Case presentation</p< <p<An ocular melanoma and a mammary mucinous carcinoma are described in an African lion (<it<Panthera leo</it<). The first tumour was histologically characterized by the presence of epithelioid and fusiform melanocytes, while the latter was composed of mucus-producing cells with an epithelial phenotype that contained periodic acid-Schiff (PAS) and Alcian blue staining mucins. Metastases of both tumor were identified in various organs and indirect immunohistochemistry was used to characterize them. Peribiliary cysts were observed in the liver.</p< <p<Conclusions</p< <p<This is the first description of these tumor in African lions.</p< <it<Panthera leo</it< Ocular neoplasms Mammary gland Melanocytic neoplasms Peribiliary cysts Veterinary medicine Salgado Breno S verfasserin aut Linardi Juliana L verfasserin aut Grandi Fabrizio verfasserin aut Rocha Rafael M verfasserin aut Rocha Noeme S verfasserin aut Teixeira Carlos R verfasserin aut Del Piero Fabio verfasserin aut Sequeira Julio L verfasserin aut In BMC Veterinary Research BMC, 2005 8(2012), 1, p 176 (DE-627)489256538 (DE-600)2191675-5 17466148 nnns volume:8 year:2012 number:1, p 176 https://doi.org/10.1186/1746-6148-8-176 kostenfrei https://doaj.org/article/3968f1cef97544649ba3416873b99fa9 kostenfrei http://www.biomedcentral.com/1746-6148/8/176 kostenfrei https://doaj.org/toc/1746-6148 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2031 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2061 GBV_ILN_2111 GBV_ILN_2113 GBV_ILN_2190 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 8 2012 1, p 176
spelling	10.1186/1746-6148-8-176 doi (DE-627)DOAJ026465892 (DE-599)DOAJ3968f1cef97544649ba3416873b99fa9 DE-627 ger DE-627 rakwb eng SF600-1100 Cagnini Didier Q verfasserin aut Ocular melanoma and mammary mucinous carcinoma in an African lion 2012 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier <p<Abstract</p< <p<Background</p< <p<Reports of neoplasms in <it<Panthera</it< species are increasing, but they are still an uncommon cause of disease and death in captive wild felids. The presence of two or more primary tumor in large felids is rarely reported, and there are no documented cases of ocular melanoma and mammary mucinous carcinoma in African lions.</p< <p<Case presentation</p< <p<An ocular melanoma and a mammary mucinous carcinoma are described in an African lion (<it<Panthera leo</it<). The first tumour was histologically characterized by the presence of epithelioid and fusiform melanocytes, while the latter was composed of mucus-producing cells with an epithelial phenotype that contained periodic acid-Schiff (PAS) and Alcian blue staining mucins. Metastases of both tumor were identified in various organs and indirect immunohistochemistry was used to characterize them. Peribiliary cysts were observed in the liver.</p< <p<Conclusions</p< <p<This is the first description of these tumor in African lions.</p< <it<Panthera leo</it< Ocular neoplasms Mammary gland Melanocytic neoplasms Peribiliary cysts Veterinary medicine Salgado Breno S verfasserin aut Linardi Juliana L verfasserin aut Grandi Fabrizio verfasserin aut Rocha Rafael M verfasserin aut Rocha Noeme S verfasserin aut Teixeira Carlos R verfasserin aut Del Piero Fabio verfasserin aut Sequeira Julio L verfasserin aut In BMC Veterinary Research BMC, 2005 8(2012), 1, p 176 (DE-627)489256538 (DE-600)2191675-5 17466148 nnns volume:8 year:2012 number:1, p 176 https://doi.org/10.1186/1746-6148-8-176 kostenfrei https://doaj.org/article/3968f1cef97544649ba3416873b99fa9 kostenfrei http://www.biomedcentral.com/1746-6148/8/176 kostenfrei https://doaj.org/toc/1746-6148 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2031 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2061 GBV_ILN_2111 GBV_ILN_2113 GBV_ILN_2190 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 8 2012 1, p 176
allfields_unstemmed	10.1186/1746-6148-8-176 doi (DE-627)DOAJ026465892 (DE-599)DOAJ3968f1cef97544649ba3416873b99fa9 DE-627 ger DE-627 rakwb eng SF600-1100 Cagnini Didier Q verfasserin aut Ocular melanoma and mammary mucinous carcinoma in an African lion 2012 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier <p<Abstract</p< <p<Background</p< <p<Reports of neoplasms in <it<Panthera</it< species are increasing, but they are still an uncommon cause of disease and death in captive wild felids. The presence of two or more primary tumor in large felids is rarely reported, and there are no documented cases of ocular melanoma and mammary mucinous carcinoma in African lions.</p< <p<Case presentation</p< <p<An ocular melanoma and a mammary mucinous carcinoma are described in an African lion (<it<Panthera leo</it<). The first tumour was histologically characterized by the presence of epithelioid and fusiform melanocytes, while the latter was composed of mucus-producing cells with an epithelial phenotype that contained periodic acid-Schiff (PAS) and Alcian blue staining mucins. Metastases of both tumor were identified in various organs and indirect immunohistochemistry was used to characterize them. Peribiliary cysts were observed in the liver.</p< <p<Conclusions</p< <p<This is the first description of these tumor in African lions.</p< <it<Panthera leo</it< Ocular neoplasms Mammary gland Melanocytic neoplasms Peribiliary cysts Veterinary medicine Salgado Breno S verfasserin aut Linardi Juliana L verfasserin aut Grandi Fabrizio verfasserin aut Rocha Rafael M verfasserin aut Rocha Noeme S verfasserin aut Teixeira Carlos R verfasserin aut Del Piero Fabio verfasserin aut Sequeira Julio L verfasserin aut In BMC Veterinary Research BMC, 2005 8(2012), 1, p 176 (DE-627)489256538 (DE-600)2191675-5 17466148 nnns volume:8 year:2012 number:1, p 176 https://doi.org/10.1186/1746-6148-8-176 kostenfrei https://doaj.org/article/3968f1cef97544649ba3416873b99fa9 kostenfrei http://www.biomedcentral.com/1746-6148/8/176 kostenfrei https://doaj.org/toc/1746-6148 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2031 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2061 GBV_ILN_2111 GBV_ILN_2113 GBV_ILN_2190 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 8 2012 1, p 176
allfieldsGer	10.1186/1746-6148-8-176 doi (DE-627)DOAJ026465892 (DE-599)DOAJ3968f1cef97544649ba3416873b99fa9 DE-627 ger DE-627 rakwb eng SF600-1100 Cagnini Didier Q verfasserin aut Ocular melanoma and mammary mucinous carcinoma in an African lion 2012 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier <p<Abstract</p< <p<Background</p< <p<Reports of neoplasms in <it<Panthera</it< species are increasing, but they are still an uncommon cause of disease and death in captive wild felids. The presence of two or more primary tumor in large felids is rarely reported, and there are no documented cases of ocular melanoma and mammary mucinous carcinoma in African lions.</p< <p<Case presentation</p< <p<An ocular melanoma and a mammary mucinous carcinoma are described in an African lion (<it<Panthera leo</it<). The first tumour was histologically characterized by the presence of epithelioid and fusiform melanocytes, while the latter was composed of mucus-producing cells with an epithelial phenotype that contained periodic acid-Schiff (PAS) and Alcian blue staining mucins. Metastases of both tumor were identified in various organs and indirect immunohistochemistry was used to characterize them. Peribiliary cysts were observed in the liver.</p< <p<Conclusions</p< <p<This is the first description of these tumor in African lions.</p< <it<Panthera leo</it< Ocular neoplasms Mammary gland Melanocytic neoplasms Peribiliary cysts Veterinary medicine Salgado Breno S verfasserin aut Linardi Juliana L verfasserin aut Grandi Fabrizio verfasserin aut Rocha Rafael M verfasserin aut Rocha Noeme S verfasserin aut Teixeira Carlos R verfasserin aut Del Piero Fabio verfasserin aut Sequeira Julio L verfasserin aut In BMC Veterinary Research BMC, 2005 8(2012), 1, p 176 (DE-627)489256538 (DE-600)2191675-5 17466148 nnns volume:8 year:2012 number:1, p 176 https://doi.org/10.1186/1746-6148-8-176 kostenfrei https://doaj.org/article/3968f1cef97544649ba3416873b99fa9 kostenfrei http://www.biomedcentral.com/1746-6148/8/176 kostenfrei https://doaj.org/toc/1746-6148 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2031 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2061 GBV_ILN_2111 GBV_ILN_2113 GBV_ILN_2190 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 8 2012 1, p 176
allfieldsSound	10.1186/1746-6148-8-176 doi (DE-627)DOAJ026465892 (DE-599)DOAJ3968f1cef97544649ba3416873b99fa9 DE-627 ger DE-627 rakwb eng SF600-1100 Cagnini Didier Q verfasserin aut Ocular melanoma and mammary mucinous carcinoma in an African lion 2012 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier <p<Abstract</p< <p<Background</p< <p<Reports of neoplasms in <it<Panthera</it< species are increasing, but they are still an uncommon cause of disease and death in captive wild felids. The presence of two or more primary tumor in large felids is rarely reported, and there are no documented cases of ocular melanoma and mammary mucinous carcinoma in African lions.</p< <p<Case presentation</p< <p<An ocular melanoma and a mammary mucinous carcinoma are described in an African lion (<it<Panthera leo</it<). The first tumour was histologically characterized by the presence of epithelioid and fusiform melanocytes, while the latter was composed of mucus-producing cells with an epithelial phenotype that contained periodic acid-Schiff (PAS) and Alcian blue staining mucins. Metastases of both tumor were identified in various organs and indirect immunohistochemistry was used to characterize them. Peribiliary cysts were observed in the liver.</p< <p<Conclusions</p< <p<This is the first description of these tumor in African lions.</p< <it<Panthera leo</it< Ocular neoplasms Mammary gland Melanocytic neoplasms Peribiliary cysts Veterinary medicine Salgado Breno S verfasserin aut Linardi Juliana L verfasserin aut Grandi Fabrizio verfasserin aut Rocha Rafael M verfasserin aut Rocha Noeme S verfasserin aut Teixeira Carlos R verfasserin aut Del Piero Fabio verfasserin aut Sequeira Julio L verfasserin aut In BMC Veterinary Research BMC, 2005 8(2012), 1, p 176 (DE-627)489256538 (DE-600)2191675-5 17466148 nnns volume:8 year:2012 number:1, p 176 https://doi.org/10.1186/1746-6148-8-176 kostenfrei https://doaj.org/article/3968f1cef97544649ba3416873b99fa9 kostenfrei http://www.biomedcentral.com/1746-6148/8/176 kostenfrei https://doaj.org/toc/1746-6148 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2031 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2061 GBV_ILN_2111 GBV_ILN_2113 GBV_ILN_2190 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 8 2012 1, p 176
language	English
source	In BMC Veterinary Research 8(2012), 1, p 176 volume:8 year:2012 number:1, p 176
sourceStr	In BMC Veterinary Research 8(2012), 1, p 176 volume:8 year:2012 number:1, p 176
format_phy_str_mv	Article
institution	findex.gbv.de
topic_facet	<it<Panthera leo</it< Ocular neoplasms Mammary gland Melanocytic neoplasms Peribiliary cysts Veterinary medicine
isfreeaccess_bool	true
container_title	BMC Veterinary Research
authorswithroles_txt_mv	Cagnini Didier Q @@aut@@ Salgado Breno S @@aut@@ Linardi Juliana L @@aut@@ Grandi Fabrizio @@aut@@ Rocha Rafael M @@aut@@ Rocha Noeme S @@aut@@ Teixeira Carlos R @@aut@@ Del Piero Fabio @@aut@@ Sequeira Julio L @@aut@@
publishDateDaySort_date	2012-01-01T00:00:00Z
hierarchy_top_id	489256538
id	DOAJ026465892
language_de	englisch
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callnumber-first	S - Agriculture
author	Cagnini Didier Q
spellingShingle	Cagnini Didier Q misc SF600-1100 misc <it<Panthera leo</it< misc Ocular neoplasms misc Mammary gland misc Melanocytic neoplasms misc Peribiliary cysts misc Veterinary medicine Ocular melanoma and mammary mucinous carcinoma in an African lion
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topic_title	SF600-1100 Ocular melanoma and mammary mucinous carcinoma in an African lion <it<Panthera leo</it< Ocular neoplasms Mammary gland Melanocytic neoplasms Peribiliary cysts
topic	misc SF600-1100 misc <it<Panthera leo</it< misc Ocular neoplasms misc Mammary gland misc Melanocytic neoplasms misc Peribiliary cysts misc Veterinary medicine
topic_unstemmed	misc SF600-1100 misc <it<Panthera leo</it< misc Ocular neoplasms misc Mammary gland misc Melanocytic neoplasms misc Peribiliary cysts misc Veterinary medicine
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title	Ocular melanoma and mammary mucinous carcinoma in an African lion
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title_full	Ocular melanoma and mammary mucinous carcinoma in an African lion
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author_browse	Cagnini Didier Q Salgado Breno S Linardi Juliana L Grandi Fabrizio Rocha Rafael M Rocha Noeme S Teixeira Carlos R Del Piero Fabio Sequeira Julio L
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title_sort	ocular melanoma and mammary mucinous carcinoma in an african lion
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title_auth	Ocular melanoma and mammary mucinous carcinoma in an African lion
abstract	<p<Abstract</p< <p<Background</p< <p<Reports of neoplasms in <it<Panthera</it< species are increasing, but they are still an uncommon cause of disease and death in captive wild felids. The presence of two or more primary tumor in large felids is rarely reported, and there are no documented cases of ocular melanoma and mammary mucinous carcinoma in African lions.</p< <p<Case presentation</p< <p<An ocular melanoma and a mammary mucinous carcinoma are described in an African lion (<it<Panthera leo</it<). The first tumour was histologically characterized by the presence of epithelioid and fusiform melanocytes, while the latter was composed of mucus-producing cells with an epithelial phenotype that contained periodic acid-Schiff (PAS) and Alcian blue staining mucins. Metastases of both tumor were identified in various organs and indirect immunohistochemistry was used to characterize them. Peribiliary cysts were observed in the liver.</p< <p<Conclusions</p< <p<This is the first description of these tumor in African lions.</p<
abstractGer	<p<Abstract</p< <p<Background</p< <p<Reports of neoplasms in <it<Panthera</it< species are increasing, but they are still an uncommon cause of disease and death in captive wild felids. The presence of two or more primary tumor in large felids is rarely reported, and there are no documented cases of ocular melanoma and mammary mucinous carcinoma in African lions.</p< <p<Case presentation</p< <p<An ocular melanoma and a mammary mucinous carcinoma are described in an African lion (<it<Panthera leo</it<). The first tumour was histologically characterized by the presence of epithelioid and fusiform melanocytes, while the latter was composed of mucus-producing cells with an epithelial phenotype that contained periodic acid-Schiff (PAS) and Alcian blue staining mucins. Metastases of both tumor were identified in various organs and indirect immunohistochemistry was used to characterize them. Peribiliary cysts were observed in the liver.</p< <p<Conclusions</p< <p<This is the first description of these tumor in African lions.</p<
abstract_unstemmed	<p<Abstract</p< <p<Background</p< <p<Reports of neoplasms in <it<Panthera</it< species are increasing, but they are still an uncommon cause of disease and death in captive wild felids. The presence of two or more primary tumor in large felids is rarely reported, and there are no documented cases of ocular melanoma and mammary mucinous carcinoma in African lions.</p< <p<Case presentation</p< <p<An ocular melanoma and a mammary mucinous carcinoma are described in an African lion (<it<Panthera leo</it<). The first tumour was histologically characterized by the presence of epithelioid and fusiform melanocytes, while the latter was composed of mucus-producing cells with an epithelial phenotype that contained periodic acid-Schiff (PAS) and Alcian blue staining mucins. Metastases of both tumor were identified in various organs and indirect immunohistochemistry was used to characterize them. Peribiliary cysts were observed in the liver.</p< <p<Conclusions</p< <p<This is the first description of these tumor in African lions.</p<
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Ocular melanoma and mammary mucinous carcinoma in an African lion

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