A survey of genome-wide association studies, polygenic scores and UK Biobank highlights resources for autoimmune disease genetics

Autoimmune diseases share a general mechanism of auto-antigens harming tissues. Still. they are phenotypically diverse, with genetic as well as environmental factors contributing to their etiology at varying degrees. Associated genomic loci and variants have been identified in numerous genome-wide a...
Ausführliche Beschreibung

Gespeichert in:
Autor*in:

Rochi Saurabh [verfasserIn]

Césaire J. K. Fouodo [verfasserIn]

Inke R. König [verfasserIn]

Hauke Busch [verfasserIn]

Inken Wohlers [verfasserIn]

Format:

E-Artikel

Sprache:

Englisch

Erschienen:

2022

Schlagwörter:

autoimmune disease

genetics

genome-wide association study

GWAS

polygenic scores

genetic risk

Übergeordnetes Werk:

In: Frontiers in Immunology - Frontiers Media S.A., 2011, 13(2022)

Übergeordnetes Werk:

volume:13 ; year:2022

Links:

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Journal toc

DOI / URN:

10.3389/fimmu.2022.972107

Katalog-ID:

DOAJ026482886

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