Minireview: Bacterial Sialyltransferases for Carbohydrate Synthesis

Sialylation catalyzed by sialyltransferases is one of the most interesting enzymatic glycosyl transfer reactions, since chemical sialylations usually give only low yields and lead to poor stereoselectivities. In the last decade, several bacterial sialyltransferases were identified and found to exhib...
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Autor*in:	Oliver Schwardt [verfasserIn] Tamara Visekruna [verfasserIn] Said Rabbani [verfasserIn] Beat Ernst [verfasserIn]

Format:	E-Artikel
Sprache:	Deutsch ; Englisch ; Französisch

Erschienen:	2006

Schlagwörter:	Bacterial sialyltransferase Chemo-enzymatic synthesis Substrate specificity

Übergeordnetes Werk:	In: CHIMIA - Swiss Chemical Society, 2020, 60(2006), 4
Übergeordnetes Werk:	volume:60 ; year:2006 ; number:4

Links:	Link aufrufen Link aufrufen Link aufrufen Journal toc Journal toc

DOI / URN:	10.2533/000942906777674787

Katalog-ID:	DOAJ026779722

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topic_facet	Bacterial sialyltransferase Chemo-enzymatic synthesis Substrate specificity Chemistry
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authorswithroles_txt_mv	Oliver Schwardt @@aut@@ Tamara Visekruna @@aut@@ Said Rabbani @@aut@@ Beat Ernst @@aut@@
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callnumber-first	Q - Science
author	Oliver Schwardt
spellingShingle	Oliver Schwardt misc QD1-999 misc Bacterial sialyltransferase misc Chemo-enzymatic synthesis misc Substrate specificity misc Chemistry Minireview: Bacterial Sialyltransferases for Carbohydrate Synthesis
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topic_title	QD1-999 Minireview: Bacterial Sialyltransferases for Carbohydrate Synthesis Bacterial sialyltransferase Chemo-enzymatic synthesis Substrate specificity
topic	misc QD1-999 misc Bacterial sialyltransferase misc Chemo-enzymatic synthesis misc Substrate specificity misc Chemistry
topic_unstemmed	misc QD1-999 misc Bacterial sialyltransferase misc Chemo-enzymatic synthesis misc Substrate specificity misc Chemistry
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title	Minireview: Bacterial Sialyltransferases for Carbohydrate Synthesis
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title_sort	minireview: bacterial sialyltransferases for carbohydrate synthesis
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title_auth	Minireview: Bacterial Sialyltransferases for Carbohydrate Synthesis
abstract	Sialylation catalyzed by sialyltransferases is one of the most interesting enzymatic glycosyl transfer reactions, since chemical sialylations usually give only low yields and lead to poor stereoselectivities. In the last decade, several bacterial sialyltransferases were identified and found to exhibit broader substrate specificity than their mammalian counterparts. This suggests the potential usefulness of bacterial sialyltransferases in chemo-enzymatic synthesis of natural and non-natural sialooligosaccharides.
abstractGer	Sialylation catalyzed by sialyltransferases is one of the most interesting enzymatic glycosyl transfer reactions, since chemical sialylations usually give only low yields and lead to poor stereoselectivities. In the last decade, several bacterial sialyltransferases were identified and found to exhibit broader substrate specificity than their mammalian counterparts. This suggests the potential usefulness of bacterial sialyltransferases in chemo-enzymatic synthesis of natural and non-natural sialooligosaccharides.
abstract_unstemmed	Sialylation catalyzed by sialyltransferases is one of the most interesting enzymatic glycosyl transfer reactions, since chemical sialylations usually give only low yields and lead to poor stereoselectivities. In the last decade, several bacterial sialyltransferases were identified and found to exhibit broader substrate specificity than their mammalian counterparts. This suggests the potential usefulness of bacterial sialyltransferases in chemo-enzymatic synthesis of natural and non-natural sialooligosaccharides.
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title_short	Minireview: Bacterial Sialyltransferases for Carbohydrate Synthesis
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