Platelet variables in community-acquired pneumonia in children with respiratory infections
Purpose: to assess the relationship of platelet variables with the etiology, severity of community-acquired pneumonia in children and the main biomarkers of systemic inflammation.Object and methods. The study included 65 children aged 9 months to 16 years 11 months with community-acquired pneumonia,...
Ausführliche Beschreibung
Autor*in: |
E. A. Kozyrev [verfasserIn] I. V. Babachenko [verfasserIn] A. V. Orlov [verfasserIn] L. A. Alekseeva [verfasserIn] E. D. Orlova [verfasserIn] |
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Russisch |
Erschienen: |
2022 |
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Übergeordnetes Werk: |
In: Журнал инфектологии - Journal Infectology, 2016, 14(2022), 1, Seite 60-68 |
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Übergeordnetes Werk: |
volume:14 ; year:2022 ; number:1 ; pages:60-68 |
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DOI / URN: |
10.22625/2072-6732-2022-14-1-60-68 |
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Katalog-ID: |
DOAJ027012174 |
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520 | |a Purpose: to assess the relationship of platelet variables with the etiology, severity of community-acquired pneumonia in children and the main biomarkers of systemic inflammation.Object and methods. The study included 65 children aged 9 months to 16 years 11 months with community-acquired pneumonia, who were treated at the clinic of Pediatric Research and Clinical Center for Infectious Diseases and the St. Olga City Children’s Hospital. Upon admission, the children underwent: complete blood count using a hematology analyzer (with the assessment of platelet parameters such as mean platelet volume, platelet distribution width, platelet large cell ratio), blood biochemistry (with the assessment of the C-reactive protein level), chest X-ray with radiographs in two projections. All children were examined for a wide range of pathogens of community-acquired pneumonia: respiratory viruses, S. pneumoniae, H. influenzae type b, M. pneumoniae, C. pneumoniae. The severity of pneumonia was assessed using the modified Respiratory Index of Severity in Children. Depending on the probable etiology, 4 groups of communityacquired pneumonia were identified: bacterial, viral, mycoplasma, and others.The results of the study. No significant differences in platelet variables depending on the etiology of pneumonia were found. In mycoplasma pneumonia, platelet variables are inversely proportional to the total white blood cell count. During the infectious process, all patients showed a significant increase in platelet count. The platelet count on admission directly correlates with the absolute white blood cell count and absolute neutrophil count. There are no significant correlations of platelet count and C-reactive protein concentration.Conclusion. There were no significant differences in platelet count depending on the etiology and severity of pediatric pneumonia. There are features of platelet variables in mycoplasma pediatric pneumonia. | ||
650 | 4 | |a внебольничная пневмония | |
650 | 4 | |a респираторные инфекции у детей | |
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10.22625/2072-6732-2022-14-1-60-68 doi (DE-627)DOAJ027012174 (DE-599)DOAJ3eaac2cfac5a4f3ab994abb30ca7238c DE-627 ger DE-627 rakwb rus RC109-216 E. A. Kozyrev verfasserin aut Platelet variables in community-acquired pneumonia in children with respiratory infections 2022 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Purpose: to assess the relationship of platelet variables with the etiology, severity of community-acquired pneumonia in children and the main biomarkers of systemic inflammation.Object and methods. The study included 65 children aged 9 months to 16 years 11 months with community-acquired pneumonia, who were treated at the clinic of Pediatric Research and Clinical Center for Infectious Diseases and the St. Olga City Children’s Hospital. Upon admission, the children underwent: complete blood count using a hematology analyzer (with the assessment of platelet parameters such as mean platelet volume, platelet distribution width, platelet large cell ratio), blood biochemistry (with the assessment of the C-reactive protein level), chest X-ray with radiographs in two projections. All children were examined for a wide range of pathogens of community-acquired pneumonia: respiratory viruses, S. pneumoniae, H. influenzae type b, M. pneumoniae, C. pneumoniae. The severity of pneumonia was assessed using the modified Respiratory Index of Severity in Children. Depending on the probable etiology, 4 groups of communityacquired pneumonia were identified: bacterial, viral, mycoplasma, and others.The results of the study. No significant differences in platelet variables depending on the etiology of pneumonia were found. In mycoplasma pneumonia, platelet variables are inversely proportional to the total white blood cell count. During the infectious process, all patients showed a significant increase in platelet count. The platelet count on admission directly correlates with the absolute white blood cell count and absolute neutrophil count. There are no significant correlations of platelet count and C-reactive protein concentration.Conclusion. There were no significant differences in platelet count depending on the etiology and severity of pediatric pneumonia. There are features of platelet variables in mycoplasma pediatric pneumonia. внебольничная пневмония респираторные инфекции у детей этиология пневмонии тромбоциты тромбоцитарные индексы Infectious and parasitic diseases I. V. Babachenko verfasserin aut A. V. Orlov verfasserin aut L. A. Alekseeva verfasserin aut E. D. Orlova verfasserin aut In Журнал инфектологии Journal Infectology, 2016 14(2022), 1, Seite 60-68 (DE-627)1735531146 20726732 nnns volume:14 year:2022 number:1 pages:60-68 https://doi.org/10.22625/2072-6732-2022-14-1-60-68 kostenfrei https://doaj.org/article/3eaac2cfac5a4f3ab994abb30ca7238c kostenfrei https://journal.niidi.ru/jofin/article/view/1309 kostenfrei https://doaj.org/toc/2072-6732 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 14 2022 1 60-68 |
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10.22625/2072-6732-2022-14-1-60-68 doi (DE-627)DOAJ027012174 (DE-599)DOAJ3eaac2cfac5a4f3ab994abb30ca7238c DE-627 ger DE-627 rakwb rus RC109-216 E. A. Kozyrev verfasserin aut Platelet variables in community-acquired pneumonia in children with respiratory infections 2022 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Purpose: to assess the relationship of platelet variables with the etiology, severity of community-acquired pneumonia in children and the main biomarkers of systemic inflammation.Object and methods. The study included 65 children aged 9 months to 16 years 11 months with community-acquired pneumonia, who were treated at the clinic of Pediatric Research and Clinical Center for Infectious Diseases and the St. Olga City Children’s Hospital. Upon admission, the children underwent: complete blood count using a hematology analyzer (with the assessment of platelet parameters such as mean platelet volume, platelet distribution width, platelet large cell ratio), blood biochemistry (with the assessment of the C-reactive protein level), chest X-ray with radiographs in two projections. All children were examined for a wide range of pathogens of community-acquired pneumonia: respiratory viruses, S. pneumoniae, H. influenzae type b, M. pneumoniae, C. pneumoniae. The severity of pneumonia was assessed using the modified Respiratory Index of Severity in Children. Depending on the probable etiology, 4 groups of communityacquired pneumonia were identified: bacterial, viral, mycoplasma, and others.The results of the study. No significant differences in platelet variables depending on the etiology of pneumonia were found. In mycoplasma pneumonia, platelet variables are inversely proportional to the total white blood cell count. During the infectious process, all patients showed a significant increase in platelet count. The platelet count on admission directly correlates with the absolute white blood cell count and absolute neutrophil count. There are no significant correlations of platelet count and C-reactive protein concentration.Conclusion. There were no significant differences in platelet count depending on the etiology and severity of pediatric pneumonia. There are features of platelet variables in mycoplasma pediatric pneumonia. внебольничная пневмония респираторные инфекции у детей этиология пневмонии тромбоциты тромбоцитарные индексы Infectious and parasitic diseases I. V. Babachenko verfasserin aut A. V. Orlov verfasserin aut L. A. Alekseeva verfasserin aut E. D. Orlova verfasserin aut In Журнал инфектологии Journal Infectology, 2016 14(2022), 1, Seite 60-68 (DE-627)1735531146 20726732 nnns volume:14 year:2022 number:1 pages:60-68 https://doi.org/10.22625/2072-6732-2022-14-1-60-68 kostenfrei https://doaj.org/article/3eaac2cfac5a4f3ab994abb30ca7238c kostenfrei https://journal.niidi.ru/jofin/article/view/1309 kostenfrei https://doaj.org/toc/2072-6732 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 14 2022 1 60-68 |
allfields_unstemmed |
10.22625/2072-6732-2022-14-1-60-68 doi (DE-627)DOAJ027012174 (DE-599)DOAJ3eaac2cfac5a4f3ab994abb30ca7238c DE-627 ger DE-627 rakwb rus RC109-216 E. A. Kozyrev verfasserin aut Platelet variables in community-acquired pneumonia in children with respiratory infections 2022 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Purpose: to assess the relationship of platelet variables with the etiology, severity of community-acquired pneumonia in children and the main biomarkers of systemic inflammation.Object and methods. The study included 65 children aged 9 months to 16 years 11 months with community-acquired pneumonia, who were treated at the clinic of Pediatric Research and Clinical Center for Infectious Diseases and the St. Olga City Children’s Hospital. Upon admission, the children underwent: complete blood count using a hematology analyzer (with the assessment of platelet parameters such as mean platelet volume, platelet distribution width, platelet large cell ratio), blood biochemistry (with the assessment of the C-reactive protein level), chest X-ray with radiographs in two projections. All children were examined for a wide range of pathogens of community-acquired pneumonia: respiratory viruses, S. pneumoniae, H. influenzae type b, M. pneumoniae, C. pneumoniae. The severity of pneumonia was assessed using the modified Respiratory Index of Severity in Children. Depending on the probable etiology, 4 groups of communityacquired pneumonia were identified: bacterial, viral, mycoplasma, and others.The results of the study. No significant differences in platelet variables depending on the etiology of pneumonia were found. In mycoplasma pneumonia, platelet variables are inversely proportional to the total white blood cell count. During the infectious process, all patients showed a significant increase in platelet count. The platelet count on admission directly correlates with the absolute white blood cell count and absolute neutrophil count. There are no significant correlations of platelet count and C-reactive protein concentration.Conclusion. There were no significant differences in platelet count depending on the etiology and severity of pediatric pneumonia. There are features of platelet variables in mycoplasma pediatric pneumonia. внебольничная пневмония респираторные инфекции у детей этиология пневмонии тромбоциты тромбоцитарные индексы Infectious and parasitic diseases I. V. Babachenko verfasserin aut A. V. Orlov verfasserin aut L. A. Alekseeva verfasserin aut E. D. Orlova verfasserin aut In Журнал инфектологии Journal Infectology, 2016 14(2022), 1, Seite 60-68 (DE-627)1735531146 20726732 nnns volume:14 year:2022 number:1 pages:60-68 https://doi.org/10.22625/2072-6732-2022-14-1-60-68 kostenfrei https://doaj.org/article/3eaac2cfac5a4f3ab994abb30ca7238c kostenfrei https://journal.niidi.ru/jofin/article/view/1309 kostenfrei https://doaj.org/toc/2072-6732 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 14 2022 1 60-68 |
allfieldsGer |
10.22625/2072-6732-2022-14-1-60-68 doi (DE-627)DOAJ027012174 (DE-599)DOAJ3eaac2cfac5a4f3ab994abb30ca7238c DE-627 ger DE-627 rakwb rus RC109-216 E. A. Kozyrev verfasserin aut Platelet variables in community-acquired pneumonia in children with respiratory infections 2022 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Purpose: to assess the relationship of platelet variables with the etiology, severity of community-acquired pneumonia in children and the main biomarkers of systemic inflammation.Object and methods. The study included 65 children aged 9 months to 16 years 11 months with community-acquired pneumonia, who were treated at the clinic of Pediatric Research and Clinical Center for Infectious Diseases and the St. Olga City Children’s Hospital. Upon admission, the children underwent: complete blood count using a hematology analyzer (with the assessment of platelet parameters such as mean platelet volume, platelet distribution width, platelet large cell ratio), blood biochemistry (with the assessment of the C-reactive protein level), chest X-ray with radiographs in two projections. All children were examined for a wide range of pathogens of community-acquired pneumonia: respiratory viruses, S. pneumoniae, H. influenzae type b, M. pneumoniae, C. pneumoniae. The severity of pneumonia was assessed using the modified Respiratory Index of Severity in Children. Depending on the probable etiology, 4 groups of communityacquired pneumonia were identified: bacterial, viral, mycoplasma, and others.The results of the study. No significant differences in platelet variables depending on the etiology of pneumonia were found. In mycoplasma pneumonia, platelet variables are inversely proportional to the total white blood cell count. During the infectious process, all patients showed a significant increase in platelet count. The platelet count on admission directly correlates with the absolute white blood cell count and absolute neutrophil count. There are no significant correlations of platelet count and C-reactive protein concentration.Conclusion. There were no significant differences in platelet count depending on the etiology and severity of pediatric pneumonia. There are features of platelet variables in mycoplasma pediatric pneumonia. внебольничная пневмония респираторные инфекции у детей этиология пневмонии тромбоциты тромбоцитарные индексы Infectious and parasitic diseases I. V. Babachenko verfasserin aut A. V. Orlov verfasserin aut L. A. Alekseeva verfasserin aut E. D. Orlova verfasserin aut In Журнал инфектологии Journal Infectology, 2016 14(2022), 1, Seite 60-68 (DE-627)1735531146 20726732 nnns volume:14 year:2022 number:1 pages:60-68 https://doi.org/10.22625/2072-6732-2022-14-1-60-68 kostenfrei https://doaj.org/article/3eaac2cfac5a4f3ab994abb30ca7238c kostenfrei https://journal.niidi.ru/jofin/article/view/1309 kostenfrei https://doaj.org/toc/2072-6732 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 14 2022 1 60-68 |
allfieldsSound |
10.22625/2072-6732-2022-14-1-60-68 doi (DE-627)DOAJ027012174 (DE-599)DOAJ3eaac2cfac5a4f3ab994abb30ca7238c DE-627 ger DE-627 rakwb rus RC109-216 E. A. Kozyrev verfasserin aut Platelet variables in community-acquired pneumonia in children with respiratory infections 2022 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Purpose: to assess the relationship of platelet variables with the etiology, severity of community-acquired pneumonia in children and the main biomarkers of systemic inflammation.Object and methods. The study included 65 children aged 9 months to 16 years 11 months with community-acquired pneumonia, who were treated at the clinic of Pediatric Research and Clinical Center for Infectious Diseases and the St. Olga City Children’s Hospital. Upon admission, the children underwent: complete blood count using a hematology analyzer (with the assessment of platelet parameters such as mean platelet volume, platelet distribution width, platelet large cell ratio), blood biochemistry (with the assessment of the C-reactive protein level), chest X-ray with radiographs in two projections. All children were examined for a wide range of pathogens of community-acquired pneumonia: respiratory viruses, S. pneumoniae, H. influenzae type b, M. pneumoniae, C. pneumoniae. The severity of pneumonia was assessed using the modified Respiratory Index of Severity in Children. Depending on the probable etiology, 4 groups of communityacquired pneumonia were identified: bacterial, viral, mycoplasma, and others.The results of the study. No significant differences in platelet variables depending on the etiology of pneumonia were found. In mycoplasma pneumonia, platelet variables are inversely proportional to the total white blood cell count. During the infectious process, all patients showed a significant increase in platelet count. The platelet count on admission directly correlates with the absolute white blood cell count and absolute neutrophil count. There are no significant correlations of platelet count and C-reactive protein concentration.Conclusion. There were no significant differences in platelet count depending on the etiology and severity of pediatric pneumonia. There are features of platelet variables in mycoplasma pediatric pneumonia. внебольничная пневмония респираторные инфекции у детей этиология пневмонии тромбоциты тромбоцитарные индексы Infectious and parasitic diseases I. V. Babachenko verfasserin aut A. V. Orlov verfasserin aut L. A. Alekseeva verfasserin aut E. D. Orlova verfasserin aut In Журнал инфектологии Journal Infectology, 2016 14(2022), 1, Seite 60-68 (DE-627)1735531146 20726732 nnns volume:14 year:2022 number:1 pages:60-68 https://doi.org/10.22625/2072-6732-2022-14-1-60-68 kostenfrei https://doaj.org/article/3eaac2cfac5a4f3ab994abb30ca7238c kostenfrei https://journal.niidi.ru/jofin/article/view/1309 kostenfrei https://doaj.org/toc/2072-6732 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 14 2022 1 60-68 |
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Platelet variables in community-acquired pneumonia in children with respiratory infections |
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Purpose: to assess the relationship of platelet variables with the etiology, severity of community-acquired pneumonia in children and the main biomarkers of systemic inflammation.Object and methods. The study included 65 children aged 9 months to 16 years 11 months with community-acquired pneumonia, who were treated at the clinic of Pediatric Research and Clinical Center for Infectious Diseases and the St. Olga City Children’s Hospital. Upon admission, the children underwent: complete blood count using a hematology analyzer (with the assessment of platelet parameters such as mean platelet volume, platelet distribution width, platelet large cell ratio), blood biochemistry (with the assessment of the C-reactive protein level), chest X-ray with radiographs in two projections. All children were examined for a wide range of pathogens of community-acquired pneumonia: respiratory viruses, S. pneumoniae, H. influenzae type b, M. pneumoniae, C. pneumoniae. The severity of pneumonia was assessed using the modified Respiratory Index of Severity in Children. Depending on the probable etiology, 4 groups of communityacquired pneumonia were identified: bacterial, viral, mycoplasma, and others.The results of the study. No significant differences in platelet variables depending on the etiology of pneumonia were found. In mycoplasma pneumonia, platelet variables are inversely proportional to the total white blood cell count. During the infectious process, all patients showed a significant increase in platelet count. The platelet count on admission directly correlates with the absolute white blood cell count and absolute neutrophil count. There are no significant correlations of platelet count and C-reactive protein concentration.Conclusion. There were no significant differences in platelet count depending on the etiology and severity of pediatric pneumonia. There are features of platelet variables in mycoplasma pediatric pneumonia. |
abstractGer |
Purpose: to assess the relationship of platelet variables with the etiology, severity of community-acquired pneumonia in children and the main biomarkers of systemic inflammation.Object and methods. The study included 65 children aged 9 months to 16 years 11 months with community-acquired pneumonia, who were treated at the clinic of Pediatric Research and Clinical Center for Infectious Diseases and the St. Olga City Children’s Hospital. Upon admission, the children underwent: complete blood count using a hematology analyzer (with the assessment of platelet parameters such as mean platelet volume, platelet distribution width, platelet large cell ratio), blood biochemistry (with the assessment of the C-reactive protein level), chest X-ray with radiographs in two projections. All children were examined for a wide range of pathogens of community-acquired pneumonia: respiratory viruses, S. pneumoniae, H. influenzae type b, M. pneumoniae, C. pneumoniae. The severity of pneumonia was assessed using the modified Respiratory Index of Severity in Children. Depending on the probable etiology, 4 groups of communityacquired pneumonia were identified: bacterial, viral, mycoplasma, and others.The results of the study. No significant differences in platelet variables depending on the etiology of pneumonia were found. In mycoplasma pneumonia, platelet variables are inversely proportional to the total white blood cell count. During the infectious process, all patients showed a significant increase in platelet count. The platelet count on admission directly correlates with the absolute white blood cell count and absolute neutrophil count. There are no significant correlations of platelet count and C-reactive protein concentration.Conclusion. There were no significant differences in platelet count depending on the etiology and severity of pediatric pneumonia. There are features of platelet variables in mycoplasma pediatric pneumonia. |
abstract_unstemmed |
Purpose: to assess the relationship of platelet variables with the etiology, severity of community-acquired pneumonia in children and the main biomarkers of systemic inflammation.Object and methods. The study included 65 children aged 9 months to 16 years 11 months with community-acquired pneumonia, who were treated at the clinic of Pediatric Research and Clinical Center for Infectious Diseases and the St. Olga City Children’s Hospital. Upon admission, the children underwent: complete blood count using a hematology analyzer (with the assessment of platelet parameters such as mean platelet volume, platelet distribution width, platelet large cell ratio), blood biochemistry (with the assessment of the C-reactive protein level), chest X-ray with radiographs in two projections. All children were examined for a wide range of pathogens of community-acquired pneumonia: respiratory viruses, S. pneumoniae, H. influenzae type b, M. pneumoniae, C. pneumoniae. The severity of pneumonia was assessed using the modified Respiratory Index of Severity in Children. Depending on the probable etiology, 4 groups of communityacquired pneumonia were identified: bacterial, viral, mycoplasma, and others.The results of the study. No significant differences in platelet variables depending on the etiology of pneumonia were found. In mycoplasma pneumonia, platelet variables are inversely proportional to the total white blood cell count. During the infectious process, all patients showed a significant increase in platelet count. The platelet count on admission directly correlates with the absolute white blood cell count and absolute neutrophil count. There are no significant correlations of platelet count and C-reactive protein concentration.Conclusion. There were no significant differences in platelet count depending on the etiology and severity of pediatric pneumonia. There are features of platelet variables in mycoplasma pediatric pneumonia. |
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https://doi.org/10.22625/2072-6732-2022-14-1-60-68 https://doaj.org/article/3eaac2cfac5a4f3ab994abb30ca7238c https://journal.niidi.ru/jofin/article/view/1309 https://doaj.org/toc/2072-6732 |
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Kozyrev</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Platelet variables in community-acquired pneumonia in children with respiratory infections</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="c">2022</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">Text</subfield><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">Computermedien</subfield><subfield code="b">c</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">Online-Ressource</subfield><subfield code="b">cr</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">Purpose: to assess the relationship of platelet variables with the etiology, severity of community-acquired pneumonia in children and the main biomarkers of systemic inflammation.Object and methods. The study included 65 children aged 9 months to 16 years 11 months with community-acquired pneumonia, who were treated at the clinic of Pediatric Research and Clinical Center for Infectious Diseases and the St. Olga City Children’s Hospital. Upon admission, the children underwent: complete blood count using a hematology analyzer (with the assessment of platelet parameters such as mean platelet volume, platelet distribution width, platelet large cell ratio), blood biochemistry (with the assessment of the C-reactive protein level), chest X-ray with radiographs in two projections. All children were examined for a wide range of pathogens of community-acquired pneumonia: respiratory viruses, S. pneumoniae, H. influenzae type b, M. pneumoniae, C. pneumoniae. The severity of pneumonia was assessed using the modified Respiratory Index of Severity in Children. Depending on the probable etiology, 4 groups of communityacquired pneumonia were identified: bacterial, viral, mycoplasma, and others.The results of the study. No significant differences in platelet variables depending on the etiology of pneumonia were found. In mycoplasma pneumonia, platelet variables are inversely proportional to the total white blood cell count. During the infectious process, all patients showed a significant increase in platelet count. The platelet count on admission directly correlates with the absolute white blood cell count and absolute neutrophil count. There are no significant correlations of platelet count and C-reactive protein concentration.Conclusion. There were no significant differences in platelet count depending on the etiology and severity of pediatric pneumonia. There are features of platelet variables in mycoplasma pediatric pneumonia.</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">внебольничная пневмония</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">респираторные инфекции у детей</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">этиология пневмонии</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">тромбоциты</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">тромбоцитарные индексы</subfield></datafield><datafield tag="653" ind1=" " ind2="0"><subfield code="a">Infectious and parasitic diseases</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">I. V. Babachenko</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">A. V. Orlov</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">L. A. Alekseeva</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">E. D. 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