Features of the response to inflammatory process in children with high and low intensity of free radical oxidations in lymphocytes during the acute period of the disease in various ethnic groups

Acute phase response represents a constellation of local and systemic reactions of the organism to the tissue damage caused by various reasons – infection, trauma, inflammation, tumor growth. So-called proteins of acute phase have a special value among the factors causing some changes in the case of inflammation. In the article the features of acute phase response to the inflammation and regulating role of adaptation hormones in the case of acute respiratory infection complicated by pneumonia in children living in the conditions of Far North (Yakutia) among the native population and the arrived one werer characterized. 112 children with acute respiratory infection accompanied by pneumonia and 42 practically healthy ones have been examined in the conditions of Far North. Both Russian and local population is forced to fight with pneumonia by the activation of free radical oxidation, i.e. usage of «respiratory explosion» reactions to get protected against inflammatory processes. The intensity difference in the biochemical response among the members of the two ethnic groups of patients is identified. Some considerable changes in С-reactive protein level, especially among Russians in the group with a high level of free radical oxidation (10 times above normal level) are noted. Higher level of α-2-macroglobulin among children with a low level of free radical oxidation is also observed in the group of Russian children. The levels of transferrin and prealbumin are characterized by a valid increase only during the period of reconvalescence, after their synthesis activation by glucocorticoids the level of which is already increased during the acute period. The conducted research has confirmed valid shifts of adaptation hormone level, acute phase proteins and free radical oxidation processes in blood of children with cute respiratory infection accompanied by pneumonia in the conditions of Far North. More expressed changes can be observed among the children of the arrived population, as being less adapted for the conditions of Far North. Ausführliche Beschreibung

Gespeichert in:

Autor*in:	V. V. Ivanova [verfasserIn] L. V. Govorova [verfasserIn] A. V. Erbasskaya [verfasserIn] L. A. Alekseeva [verfasserIn]

Format:	E-Artikel
Sprache:	Russisch

Erschienen:	2014

Schlagwörter:	острые респираторные инфекции пневмонии свободно-радикальное окисление белки острой фазы гормоны «стресса» соматотропный гормон кортизол

Übergeordnetes Werk:	In: Журнал инфектологии - Journal Infectology, 2016, 4(2014), 3, Seite 46-52
Übergeordnetes Werk:	volume:4 ; year:2014 ; number:3 ; pages:46-52

Links:	Link aufrufen Link aufrufen Link aufrufen Journal toc

DOI / URN:	10.22625/2072-6732-2012-4-3-46-52

Katalog-ID:	DOAJ027100480

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allfields_unstemmed	10.22625/2072-6732-2012-4-3-46-52 doi (DE-627)DOAJ027100480 (DE-599)DOAJ7e3bbed48806432cb89479fc40f883cc DE-627 ger DE-627 rakwb rus RC109-216 V. V. Ivanova verfasserin aut Features of the response to inflammatory process in children with high and low intensity of free radical oxidations in lymphocytes during the acute period of the disease in various ethnic groups 2014 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Acute phase response represents a constellation of local and systemic reactions of the organism to the tissue damage caused by various reasons – infection, trauma, inflammation, tumor growth. So-called proteins of acute phase have a special value among the factors causing some changes in the case of inflammation. In the article the features of acute phase response to the inflammation and regulating role of adaptation hormones in the case of acute respiratory infection complicated by pneumonia in children living in the conditions of Far North (Yakutia) among the native population and the arrived one werer characterized. 112 children with acute respiratory infection accompanied by pneumonia and 42 practically healthy ones have been examined in the conditions of Far North. Both Russian and local population is forced to fight with pneumonia by the activation of free radical oxidation, i.e. usage of «respiratory explosion» reactions to get protected against inflammatory processes. The intensity difference in the biochemical response among the members of the two ethnic groups of patients is identified. Some considerable changes in С-reactive protein level, especially among Russians in the group with a high level of free radical oxidation (10 times above normal level) are noted. Higher level of α-2-macroglobulin among children with a low level of free radical oxidation is also observed in the group of Russian children. The levels of transferrin and prealbumin are characterized by a valid increase only during the period of reconvalescence, after their synthesis activation by glucocorticoids the level of which is already increased during the acute period. The conducted research has confirmed valid shifts of adaptation hormone level, acute phase proteins and free radical oxidation processes in blood of children with cute respiratory infection accompanied by pneumonia in the conditions of Far North. More expressed changes can be observed among the children of the arrived population, as being less adapted for the conditions of Far North. острые респираторные инфекции пневмонии свободно-радикальное окисление белки острой фазы гормоны «стресса» соматотропный гормон кортизол Infectious and parasitic diseases L. V. Govorova verfasserin aut A. V. Erbasskaya verfasserin aut L. A. Alekseeva verfasserin aut In Журнал инфектологии Journal Infectology, 2016 4(2014), 3, Seite 46-52 (DE-627)1735531146 20726732 nnns volume:4 year:2014 number:3 pages:46-52 https://doi.org/10.22625/2072-6732-2012-4-3-46-52 kostenfrei https://doaj.org/article/7e3bbed48806432cb89479fc40f883cc kostenfrei https://journal.niidi.ru/jofin/article/view/113 kostenfrei https://doaj.org/toc/2072-6732 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 4 2014 3 46-52
allfieldsGer	10.22625/2072-6732-2012-4-3-46-52 doi (DE-627)DOAJ027100480 (DE-599)DOAJ7e3bbed48806432cb89479fc40f883cc DE-627 ger DE-627 rakwb rus RC109-216 V. V. Ivanova verfasserin aut Features of the response to inflammatory process in children with high and low intensity of free radical oxidations in lymphocytes during the acute period of the disease in various ethnic groups 2014 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Acute phase response represents a constellation of local and systemic reactions of the organism to the tissue damage caused by various reasons – infection, trauma, inflammation, tumor growth. So-called proteins of acute phase have a special value among the factors causing some changes in the case of inflammation. In the article the features of acute phase response to the inflammation and regulating role of adaptation hormones in the case of acute respiratory infection complicated by pneumonia in children living in the conditions of Far North (Yakutia) among the native population and the arrived one werer characterized. 112 children with acute respiratory infection accompanied by pneumonia and 42 practically healthy ones have been examined in the conditions of Far North. Both Russian and local population is forced to fight with pneumonia by the activation of free radical oxidation, i.e. usage of «respiratory explosion» reactions to get protected against inflammatory processes. The intensity difference in the biochemical response among the members of the two ethnic groups of patients is identified. Some considerable changes in С-reactive protein level, especially among Russians in the group with a high level of free radical oxidation (10 times above normal level) are noted. Higher level of α-2-macroglobulin among children with a low level of free radical oxidation is also observed in the group of Russian children. The levels of transferrin and prealbumin are characterized by a valid increase only during the period of reconvalescence, after their synthesis activation by glucocorticoids the level of which is already increased during the acute period. The conducted research has confirmed valid shifts of adaptation hormone level, acute phase proteins and free radical oxidation processes in blood of children with cute respiratory infection accompanied by pneumonia in the conditions of Far North. More expressed changes can be observed among the children of the arrived population, as being less adapted for the conditions of Far North. острые респираторные инфекции пневмонии свободно-радикальное окисление белки острой фазы гормоны «стресса» соматотропный гормон кортизол Infectious and parasitic diseases L. V. Govorova verfasserin aut A. V. Erbasskaya verfasserin aut L. A. Alekseeva verfasserin aut In Журнал инфектологии Journal Infectology, 2016 4(2014), 3, Seite 46-52 (DE-627)1735531146 20726732 nnns volume:4 year:2014 number:3 pages:46-52 https://doi.org/10.22625/2072-6732-2012-4-3-46-52 kostenfrei https://doaj.org/article/7e3bbed48806432cb89479fc40f883cc kostenfrei https://journal.niidi.ru/jofin/article/view/113 kostenfrei https://doaj.org/toc/2072-6732 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 4 2014 3 46-52
allfieldsSound	10.22625/2072-6732-2012-4-3-46-52 doi (DE-627)DOAJ027100480 (DE-599)DOAJ7e3bbed48806432cb89479fc40f883cc DE-627 ger DE-627 rakwb rus RC109-216 V. V. Ivanova verfasserin aut Features of the response to inflammatory process in children with high and low intensity of free radical oxidations in lymphocytes during the acute period of the disease in various ethnic groups 2014 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Acute phase response represents a constellation of local and systemic reactions of the organism to the tissue damage caused by various reasons – infection, trauma, inflammation, tumor growth. So-called proteins of acute phase have a special value among the factors causing some changes in the case of inflammation. In the article the features of acute phase response to the inflammation and regulating role of adaptation hormones in the case of acute respiratory infection complicated by pneumonia in children living in the conditions of Far North (Yakutia) among the native population and the arrived one werer characterized. 112 children with acute respiratory infection accompanied by pneumonia and 42 practically healthy ones have been examined in the conditions of Far North. Both Russian and local population is forced to fight with pneumonia by the activation of free radical oxidation, i.e. usage of «respiratory explosion» reactions to get protected against inflammatory processes. The intensity difference in the biochemical response among the members of the two ethnic groups of patients is identified. Some considerable changes in С-reactive protein level, especially among Russians in the group with a high level of free radical oxidation (10 times above normal level) are noted. Higher level of α-2-macroglobulin among children with a low level of free radical oxidation is also observed in the group of Russian children. The levels of transferrin and prealbumin are characterized by a valid increase only during the period of reconvalescence, after their synthesis activation by glucocorticoids the level of which is already increased during the acute period. The conducted research has confirmed valid shifts of adaptation hormone level, acute phase proteins and free radical oxidation processes in blood of children with cute respiratory infection accompanied by pneumonia in the conditions of Far North. More expressed changes can be observed among the children of the arrived population, as being less adapted for the conditions of Far North. острые респираторные инфекции пневмонии свободно-радикальное окисление белки острой фазы гормоны «стресса» соматотропный гормон кортизол Infectious and parasitic diseases L. V. Govorova verfasserin aut A. V. Erbasskaya verfasserin aut L. A. Alekseeva verfasserin aut In Журнал инфектологии Journal Infectology, 2016 4(2014), 3, Seite 46-52 (DE-627)1735531146 20726732 nnns volume:4 year:2014 number:3 pages:46-52 https://doi.org/10.22625/2072-6732-2012-4-3-46-52 kostenfrei https://doaj.org/article/7e3bbed48806432cb89479fc40f883cc kostenfrei https://journal.niidi.ru/jofin/article/view/113 kostenfrei https://doaj.org/toc/2072-6732 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 4 2014 3 46-52
language	Russian
source	In Журнал инфектологии 4(2014), 3, Seite 46-52 volume:4 year:2014 number:3 pages:46-52
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topic_facet	острые респираторные инфекции пневмонии свободно-радикальное окисление белки острой фазы гормоны «стресса» соматотропный гормон кортизол Infectious and parasitic diseases
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authorswithroles_txt_mv	V. V. Ivanova @@aut@@ L. V. Govorova @@aut@@ A. V. Erbasskaya @@aut@@ L. A. Alekseeva @@aut@@
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callnumber-first	R - Medicine
author	V. V. Ivanova
spellingShingle	V. V. Ivanova misc RC109-216 misc острые респираторные инфекции misc пневмонии misc свободно-радикальное окисление misc белки острой фазы misc гормоны «стресса» misc соматотропный гормон misc кортизол misc Infectious and parasitic diseases Features of the response to inflammatory process in children with high and low intensity of free radical oxidations in lymphocytes during the acute period of the disease in various ethnic groups
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topic_title	RC109-216 Features of the response to inflammatory process in children with high and low intensity of free radical oxidations in lymphocytes during the acute period of the disease in various ethnic groups острые респираторные инфекции пневмонии свободно-радикальное окисление белки острой фазы гормоны «стресса» соматотропный гормон кортизол
topic	misc RC109-216 misc острые респираторные инфекции misc пневмонии misc свободно-радикальное окисление misc белки острой фазы misc гормоны «стресса» misc соматотропный гормон misc кортизол misc Infectious and parasitic diseases
topic_unstemmed	misc RC109-216 misc острые респираторные инфекции misc пневмонии misc свободно-радикальное окисление misc белки острой фазы misc гормоны «стресса» misc соматотропный гормон misc кортизол misc Infectious and parasitic diseases
topic_browse	misc RC109-216 misc острые респираторные инфекции misc пневмонии misc свободно-радикальное окисление misc белки острой фазы misc гормоны «стресса» misc соматотропный гормон misc кортизол misc Infectious and parasitic diseases
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title	Features of the response to inflammatory process in children with high and low intensity of free radical oxidations in lymphocytes during the acute period of the disease in various ethnic groups
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title_full	Features of the response to inflammatory process in children with high and low intensity of free radical oxidations in lymphocytes during the acute period of the disease in various ethnic groups
author_sort	V. V. Ivanova
journal	Журнал инфектологии
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author_browse	V. V. Ivanova L. V. Govorova A. V. Erbasskaya L. A. Alekseeva
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class	RC109-216
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author-letter	V. V. Ivanova
doi_str_mv	10.22625/2072-6732-2012-4-3-46-52
author2-role	verfasserin
title_sort	features of the response to inflammatory process in children with high and low intensity of free radical oxidations in lymphocytes during the acute period of the disease in various ethnic groups
callnumber	RC109-216
title_auth	Features of the response to inflammatory process in children with high and low intensity of free radical oxidations in lymphocytes during the acute period of the disease in various ethnic groups
abstract	Acute phase response represents a constellation of local and systemic reactions of the organism to the tissue damage caused by various reasons – infection, trauma, inflammation, tumor growth. So-called proteins of acute phase have a special value among the factors causing some changes in the case of inflammation. In the article the features of acute phase response to the inflammation and regulating role of adaptation hormones in the case of acute respiratory infection complicated by pneumonia in children living in the conditions of Far North (Yakutia) among the native population and the arrived one werer characterized. 112 children with acute respiratory infection accompanied by pneumonia and 42 practically healthy ones have been examined in the conditions of Far North. Both Russian and local population is forced to fight with pneumonia by the activation of free radical oxidation, i.e. usage of «respiratory explosion» reactions to get protected against inflammatory processes. The intensity difference in the biochemical response among the members of the two ethnic groups of patients is identified. Some considerable changes in С-reactive protein level, especially among Russians in the group with a high level of free radical oxidation (10 times above normal level) are noted. Higher level of α-2-macroglobulin among children with a low level of free radical oxidation is also observed in the group of Russian children. The levels of transferrin and prealbumin are characterized by a valid increase only during the period of reconvalescence, after their synthesis activation by glucocorticoids the level of which is already increased during the acute period. The conducted research has confirmed valid shifts of adaptation hormone level, acute phase proteins and free radical oxidation processes in blood of children with cute respiratory infection accompanied by pneumonia in the conditions of Far North. More expressed changes can be observed among the children of the arrived population, as being less adapted for the conditions of Far North.
abstractGer	Acute phase response represents a constellation of local and systemic reactions of the organism to the tissue damage caused by various reasons – infection, trauma, inflammation, tumor growth. So-called proteins of acute phase have a special value among the factors causing some changes in the case of inflammation. In the article the features of acute phase response to the inflammation and regulating role of adaptation hormones in the case of acute respiratory infection complicated by pneumonia in children living in the conditions of Far North (Yakutia) among the native population and the arrived one werer characterized. 112 children with acute respiratory infection accompanied by pneumonia and 42 practically healthy ones have been examined in the conditions of Far North. Both Russian and local population is forced to fight with pneumonia by the activation of free radical oxidation, i.e. usage of «respiratory explosion» reactions to get protected against inflammatory processes. The intensity difference in the biochemical response among the members of the two ethnic groups of patients is identified. Some considerable changes in С-reactive protein level, especially among Russians in the group with a high level of free radical oxidation (10 times above normal level) are noted. Higher level of α-2-macroglobulin among children with a low level of free radical oxidation is also observed in the group of Russian children. The levels of transferrin and prealbumin are characterized by a valid increase only during the period of reconvalescence, after their synthesis activation by glucocorticoids the level of which is already increased during the acute period. The conducted research has confirmed valid shifts of adaptation hormone level, acute phase proteins and free radical oxidation processes in blood of children with cute respiratory infection accompanied by pneumonia in the conditions of Far North. More expressed changes can be observed among the children of the arrived population, as being less adapted for the conditions of Far North.
abstract_unstemmed	Acute phase response represents a constellation of local and systemic reactions of the organism to the tissue damage caused by various reasons – infection, trauma, inflammation, tumor growth. So-called proteins of acute phase have a special value among the factors causing some changes in the case of inflammation. In the article the features of acute phase response to the inflammation and regulating role of adaptation hormones in the case of acute respiratory infection complicated by pneumonia in children living in the conditions of Far North (Yakutia) among the native population and the arrived one werer characterized. 112 children with acute respiratory infection accompanied by pneumonia and 42 practically healthy ones have been examined in the conditions of Far North. Both Russian and local population is forced to fight with pneumonia by the activation of free radical oxidation, i.e. usage of «respiratory explosion» reactions to get protected against inflammatory processes. The intensity difference in the biochemical response among the members of the two ethnic groups of patients is identified. Some considerable changes in С-reactive protein level, especially among Russians in the group with a high level of free radical oxidation (10 times above normal level) are noted. Higher level of α-2-macroglobulin among children with a low level of free radical oxidation is also observed in the group of Russian children. The levels of transferrin and prealbumin are characterized by a valid increase only during the period of reconvalescence, after their synthesis activation by glucocorticoids the level of which is already increased during the acute period. The conducted research has confirmed valid shifts of adaptation hormone level, acute phase proteins and free radical oxidation processes in blood of children with cute respiratory infection accompanied by pneumonia in the conditions of Far North. More expressed changes can be observed among the children of the arrived population, as being less adapted for the conditions of Far North.
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title_short	Features of the response to inflammatory process in children with high and low intensity of free radical oxidations in lymphocytes during the acute period of the disease in various ethnic groups
url	https://doi.org/10.22625/2072-6732-2012-4-3-46-52 https://doaj.org/article/7e3bbed48806432cb89479fc40f883cc https://journal.niidi.ru/jofin/article/view/113 https://doaj.org/toc/2072-6732
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