The genome of Nectria haematococca: contribution of supernumerary chromosomes to gene expansion.
The ascomycetous fungus Nectria haematococca, (asexual name Fusarium solani), is a member of a group of <50 species known as the "Fusarium solani species complex". Members of this complex have diverse biological properties including the ability to cause disease on <100 genera of plan...
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| Autor*in: |
Jeffrey J Coleman [verfasserIn] Steve D Rounsley [verfasserIn] Marianela Rodriguez-Carres [verfasserIn] Alan Kuo [verfasserIn] Catherine C Wasmann [verfasserIn] Jane Grimwood [verfasserIn] Jeremy Schmutz [verfasserIn] Masatoki Taga [verfasserIn] Gerard J White [verfasserIn] Shiguo Zhou [verfasserIn] David C Schwartz [verfasserIn] Michael Freitag [verfasserIn] Li-Jun Ma [verfasserIn] Etienne G J Danchin [verfasserIn] Bernard Henrissat [verfasserIn] Pedro M Coutinho [verfasserIn] David R Nelson [verfasserIn] Dave Straney [verfasserIn] Carolyn A Napoli [verfasserIn] Bridget M Barker [verfasserIn] Michael Gribskov [verfasserIn] Martijn Rep [verfasserIn] Scott Kroken [verfasserIn] István Molnár [verfasserIn] Christopher Rensing [verfasserIn] John C Kennell [verfasserIn] Jorge Zamora [verfasserIn] Mark L Farman [verfasserIn] Eric U Selker [verfasserIn] Asaf Salamov [verfasserIn] Harris Shapiro [verfasserIn] Jasmyn Pangilinan [verfasserIn] Erika Lindquist [verfasserIn] Casey Lamers [verfasserIn] Igor V Grigoriev [verfasserIn] David M Geiser [verfasserIn] Sarah F Covert [verfasserIn] Esteban Temporini [verfasserIn] Hans D Vanetten [verfasserIn] |
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| Format: |
E-Artikel |
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| Sprache: |
Englisch |
| Erschienen: |
2009 |
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| Übergeordnetes Werk: |
In: PLoS Genetics - Public Library of Science (PLoS), 2005, 5(2009), 8, p e1000618 |
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| Übergeordnetes Werk: |
volume:5 ; year:2009 ; number:8, p e1000618 |
| Links: |
Link aufrufen |
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| DOI / URN: |
10.1371/journal.pgen.1000618 |
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| Katalog-ID: |
DOAJ027157342 |
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| 245 | 1 | 4 | |a The genome of Nectria haematococca: contribution of supernumerary chromosomes to gene expansion. |
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| 520 | |a The ascomycetous fungus Nectria haematococca, (asexual name Fusarium solani), is a member of a group of <50 species known as the "Fusarium solani species complex". Members of this complex have diverse biological properties including the ability to cause disease on <100 genera of plants and opportunistic infections in humans. The current research analyzed the most extensively studied member of this complex, N. haematococca mating population VI (MPVI). Several genes controlling the ability of individual isolates of this species to colonize specific habitats are located on supernumerary chromosomes. Optical mapping revealed that the sequenced isolate has 17 chromosomes ranging from 530 kb to 6.52 Mb and that the physical size of the genome, 54.43 Mb, and the number of predicted genes, 15,707, are among the largest reported for ascomycetes. Two classes of genes have contributed to gene expansion: specific genes that are not found in other fungi including its closest sequenced relative, Fusarium graminearum; and genes that commonly occur as single copies in other fungi but are present as multiple copies in N. haematococca MPVI. Some of these additional genes appear to have resulted from gene duplication events, while others may have been acquired through horizontal gene transfer. The supernumerary nature of three chromosomes, 14, 15, and 17, was confirmed by their absence in pulsed field gel electrophoresis experiments of some isolates and by demonstrating that these isolates lacked chromosome-specific sequences found on the ends of these chromosomes. These supernumerary chromosomes contain more repeat sequences, are enriched in unique and duplicated genes, and have a lower G+C content in comparison to the other chromosomes. Although the origin(s) of the extra genes and the supernumerary chromosomes is not known, the gene expansion and its large genome size are consistent with this species' diverse range of habitats. Furthermore, the presence of unique genes on supernumerary chromosomes might account for individual isolates having different environmental niches. | ||
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10.1371/journal.pgen.1000618 doi (DE-627)DOAJ027157342 (DE-599)DOAJ82be34517e7a4e04b545733a7dc28bc9 DE-627 ger DE-627 rakwb eng QH426-470 Jeffrey J Coleman verfasserin aut The genome of Nectria haematococca: contribution of supernumerary chromosomes to gene expansion. 2009 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier The ascomycetous fungus Nectria haematococca, (asexual name Fusarium solani), is a member of a group of <50 species known as the "Fusarium solani species complex". Members of this complex have diverse biological properties including the ability to cause disease on <100 genera of plants and opportunistic infections in humans. The current research analyzed the most extensively studied member of this complex, N. haematococca mating population VI (MPVI). Several genes controlling the ability of individual isolates of this species to colonize specific habitats are located on supernumerary chromosomes. Optical mapping revealed that the sequenced isolate has 17 chromosomes ranging from 530 kb to 6.52 Mb and that the physical size of the genome, 54.43 Mb, and the number of predicted genes, 15,707, are among the largest reported for ascomycetes. Two classes of genes have contributed to gene expansion: specific genes that are not found in other fungi including its closest sequenced relative, Fusarium graminearum; and genes that commonly occur as single copies in other fungi but are present as multiple copies in N. haematococca MPVI. Some of these additional genes appear to have resulted from gene duplication events, while others may have been acquired through horizontal gene transfer. The supernumerary nature of three chromosomes, 14, 15, and 17, was confirmed by their absence in pulsed field gel electrophoresis experiments of some isolates and by demonstrating that these isolates lacked chromosome-specific sequences found on the ends of these chromosomes. These supernumerary chromosomes contain more repeat sequences, are enriched in unique and duplicated genes, and have a lower G+C content in comparison to the other chromosomes. Although the origin(s) of the extra genes and the supernumerary chromosomes is not known, the gene expansion and its large genome size are consistent with this species' diverse range of habitats. Furthermore, the presence of unique genes on supernumerary chromosomes might account for individual isolates having different environmental niches. Genetics Steve D Rounsley verfasserin aut Marianela Rodriguez-Carres verfasserin aut Alan Kuo verfasserin aut Catherine C Wasmann verfasserin aut Jane Grimwood verfasserin aut Jeremy Schmutz verfasserin aut Masatoki Taga verfasserin aut Gerard J White verfasserin aut Shiguo Zhou verfasserin aut David C Schwartz verfasserin aut Michael Freitag verfasserin aut Li-Jun Ma verfasserin aut Etienne G J Danchin verfasserin aut Bernard Henrissat verfasserin aut Pedro M Coutinho verfasserin aut David R Nelson verfasserin aut Dave Straney verfasserin aut Carolyn A Napoli verfasserin aut Bridget M Barker verfasserin aut Michael Gribskov verfasserin aut Martijn Rep verfasserin aut Scott Kroken verfasserin aut István Molnár verfasserin aut Christopher Rensing verfasserin aut John C Kennell verfasserin aut Jorge Zamora verfasserin aut Mark L Farman verfasserin aut Eric U Selker verfasserin aut Asaf Salamov verfasserin aut Harris Shapiro verfasserin aut Jasmyn Pangilinan verfasserin aut Erika Lindquist verfasserin aut Casey Lamers verfasserin aut Igor V Grigoriev verfasserin aut David M Geiser verfasserin aut Sarah F Covert verfasserin aut Esteban Temporini verfasserin aut Hans D Vanetten verfasserin aut In PLoS Genetics Public Library of Science (PLoS), 2005 5(2009), 8, p e1000618 (DE-627)485248026 (DE-600)2186725-2 15537404 nnns volume:5 year:2009 number:8, p e1000618 https://doi.org/10.1371/journal.pgen.1000618 kostenfrei https://doaj.org/article/82be34517e7a4e04b545733a7dc28bc9 kostenfrei http://europepmc.org/articles/PMC2725324?pdf=render kostenfrei https://doaj.org/toc/1553-7390 Journal toc kostenfrei https://doaj.org/toc/1553-7404 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2031 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2061 GBV_ILN_2111 GBV_ILN_2113 GBV_ILN_2190 GBV_ILN_2522 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 5 2009 8, p e1000618 |
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10.1371/journal.pgen.1000618 doi (DE-627)DOAJ027157342 (DE-599)DOAJ82be34517e7a4e04b545733a7dc28bc9 DE-627 ger DE-627 rakwb eng QH426-470 Jeffrey J Coleman verfasserin aut The genome of Nectria haematococca: contribution of supernumerary chromosomes to gene expansion. 2009 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier The ascomycetous fungus Nectria haematococca, (asexual name Fusarium solani), is a member of a group of <50 species known as the "Fusarium solani species complex". Members of this complex have diverse biological properties including the ability to cause disease on <100 genera of plants and opportunistic infections in humans. The current research analyzed the most extensively studied member of this complex, N. haematococca mating population VI (MPVI). Several genes controlling the ability of individual isolates of this species to colonize specific habitats are located on supernumerary chromosomes. Optical mapping revealed that the sequenced isolate has 17 chromosomes ranging from 530 kb to 6.52 Mb and that the physical size of the genome, 54.43 Mb, and the number of predicted genes, 15,707, are among the largest reported for ascomycetes. Two classes of genes have contributed to gene expansion: specific genes that are not found in other fungi including its closest sequenced relative, Fusarium graminearum; and genes that commonly occur as single copies in other fungi but are present as multiple copies in N. haematococca MPVI. Some of these additional genes appear to have resulted from gene duplication events, while others may have been acquired through horizontal gene transfer. The supernumerary nature of three chromosomes, 14, 15, and 17, was confirmed by their absence in pulsed field gel electrophoresis experiments of some isolates and by demonstrating that these isolates lacked chromosome-specific sequences found on the ends of these chromosomes. These supernumerary chromosomes contain more repeat sequences, are enriched in unique and duplicated genes, and have a lower G+C content in comparison to the other chromosomes. Although the origin(s) of the extra genes and the supernumerary chromosomes is not known, the gene expansion and its large genome size are consistent with this species' diverse range of habitats. Furthermore, the presence of unique genes on supernumerary chromosomes might account for individual isolates having different environmental niches. Genetics Steve D Rounsley verfasserin aut Marianela Rodriguez-Carres verfasserin aut Alan Kuo verfasserin aut Catherine C Wasmann verfasserin aut Jane Grimwood verfasserin aut Jeremy Schmutz verfasserin aut Masatoki Taga verfasserin aut Gerard J White verfasserin aut Shiguo Zhou verfasserin aut David C Schwartz verfasserin aut Michael Freitag verfasserin aut Li-Jun Ma verfasserin aut Etienne G J Danchin verfasserin aut Bernard Henrissat verfasserin aut Pedro M Coutinho verfasserin aut David R Nelson verfasserin aut Dave Straney verfasserin aut Carolyn A Napoli verfasserin aut Bridget M Barker verfasserin aut Michael Gribskov verfasserin aut Martijn Rep verfasserin aut Scott Kroken verfasserin aut István Molnár verfasserin aut Christopher Rensing verfasserin aut John C Kennell verfasserin aut Jorge Zamora verfasserin aut Mark L Farman verfasserin aut Eric U Selker verfasserin aut Asaf Salamov verfasserin aut Harris Shapiro verfasserin aut Jasmyn Pangilinan verfasserin aut Erika Lindquist verfasserin aut Casey Lamers verfasserin aut Igor V Grigoriev verfasserin aut David M Geiser verfasserin aut Sarah F Covert verfasserin aut Esteban Temporini verfasserin aut Hans D Vanetten verfasserin aut In PLoS Genetics Public Library of Science (PLoS), 2005 5(2009), 8, p e1000618 (DE-627)485248026 (DE-600)2186725-2 15537404 nnns volume:5 year:2009 number:8, p e1000618 https://doi.org/10.1371/journal.pgen.1000618 kostenfrei https://doaj.org/article/82be34517e7a4e04b545733a7dc28bc9 kostenfrei http://europepmc.org/articles/PMC2725324?pdf=render kostenfrei https://doaj.org/toc/1553-7390 Journal toc kostenfrei https://doaj.org/toc/1553-7404 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2031 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2061 GBV_ILN_2111 GBV_ILN_2113 GBV_ILN_2190 GBV_ILN_2522 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 5 2009 8, p e1000618 |
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10.1371/journal.pgen.1000618 doi (DE-627)DOAJ027157342 (DE-599)DOAJ82be34517e7a4e04b545733a7dc28bc9 DE-627 ger DE-627 rakwb eng QH426-470 Jeffrey J Coleman verfasserin aut The genome of Nectria haematococca: contribution of supernumerary chromosomes to gene expansion. 2009 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier The ascomycetous fungus Nectria haematococca, (asexual name Fusarium solani), is a member of a group of <50 species known as the "Fusarium solani species complex". Members of this complex have diverse biological properties including the ability to cause disease on <100 genera of plants and opportunistic infections in humans. The current research analyzed the most extensively studied member of this complex, N. haematococca mating population VI (MPVI). Several genes controlling the ability of individual isolates of this species to colonize specific habitats are located on supernumerary chromosomes. Optical mapping revealed that the sequenced isolate has 17 chromosomes ranging from 530 kb to 6.52 Mb and that the physical size of the genome, 54.43 Mb, and the number of predicted genes, 15,707, are among the largest reported for ascomycetes. Two classes of genes have contributed to gene expansion: specific genes that are not found in other fungi including its closest sequenced relative, Fusarium graminearum; and genes that commonly occur as single copies in other fungi but are present as multiple copies in N. haematococca MPVI. Some of these additional genes appear to have resulted from gene duplication events, while others may have been acquired through horizontal gene transfer. The supernumerary nature of three chromosomes, 14, 15, and 17, was confirmed by their absence in pulsed field gel electrophoresis experiments of some isolates and by demonstrating that these isolates lacked chromosome-specific sequences found on the ends of these chromosomes. These supernumerary chromosomes contain more repeat sequences, are enriched in unique and duplicated genes, and have a lower G+C content in comparison to the other chromosomes. Although the origin(s) of the extra genes and the supernumerary chromosomes is not known, the gene expansion and its large genome size are consistent with this species' diverse range of habitats. Furthermore, the presence of unique genes on supernumerary chromosomes might account for individual isolates having different environmental niches. Genetics Steve D Rounsley verfasserin aut Marianela Rodriguez-Carres verfasserin aut Alan Kuo verfasserin aut Catherine C Wasmann verfasserin aut Jane Grimwood verfasserin aut Jeremy Schmutz verfasserin aut Masatoki Taga verfasserin aut Gerard J White verfasserin aut Shiguo Zhou verfasserin aut David C Schwartz verfasserin aut Michael Freitag verfasserin aut Li-Jun Ma verfasserin aut Etienne G J Danchin verfasserin aut Bernard Henrissat verfasserin aut Pedro M Coutinho verfasserin aut David R Nelson verfasserin aut Dave Straney verfasserin aut Carolyn A Napoli verfasserin aut Bridget M Barker verfasserin aut Michael Gribskov verfasserin aut Martijn Rep verfasserin aut Scott Kroken verfasserin aut István Molnár verfasserin aut Christopher Rensing verfasserin aut John C Kennell verfasserin aut Jorge Zamora verfasserin aut Mark L Farman verfasserin aut Eric U Selker verfasserin aut Asaf Salamov verfasserin aut Harris Shapiro verfasserin aut Jasmyn Pangilinan verfasserin aut Erika Lindquist verfasserin aut Casey Lamers verfasserin aut Igor V Grigoriev verfasserin aut David M Geiser verfasserin aut Sarah F Covert verfasserin aut Esteban Temporini verfasserin aut Hans D Vanetten verfasserin aut In PLoS Genetics Public Library of Science (PLoS), 2005 5(2009), 8, p e1000618 (DE-627)485248026 (DE-600)2186725-2 15537404 nnns volume:5 year:2009 number:8, p e1000618 https://doi.org/10.1371/journal.pgen.1000618 kostenfrei https://doaj.org/article/82be34517e7a4e04b545733a7dc28bc9 kostenfrei http://europepmc.org/articles/PMC2725324?pdf=render kostenfrei https://doaj.org/toc/1553-7390 Journal toc kostenfrei https://doaj.org/toc/1553-7404 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2031 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2061 GBV_ILN_2111 GBV_ILN_2113 GBV_ILN_2190 GBV_ILN_2522 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 5 2009 8, p e1000618 |
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Optical mapping revealed that the sequenced isolate has 17 chromosomes ranging from 530 kb to 6.52 Mb and that the physical size of the genome, 54.43 Mb, and the number of predicted genes, 15,707, are among the largest reported for ascomycetes. Two classes of genes have contributed to gene expansion: specific genes that are not found in other fungi including its closest sequenced relative, Fusarium graminearum; and genes that commonly occur as single copies in other fungi but are present as multiple copies in N. haematococca MPVI. Some of these additional genes appear to have resulted from gene duplication events, while others may have been acquired through horizontal gene transfer. The supernumerary nature of three chromosomes, 14, 15, and 17, was confirmed by their absence in pulsed field gel electrophoresis experiments of some isolates and by demonstrating that these isolates lacked chromosome-specific sequences found on the ends of these chromosomes. These supernumerary chromosomes contain more repeat sequences, are enriched in unique and duplicated genes, and have a lower G+C content in comparison to the other chromosomes. Although the origin(s) of the extra genes and the supernumerary chromosomes is not known, the gene expansion and its large genome size are consistent with this species' diverse range of habitats. Furthermore, the presence of unique genes on supernumerary chromosomes might account for individual isolates having different environmental niches. Genetics Steve D Rounsley verfasserin aut Marianela Rodriguez-Carres verfasserin aut Alan Kuo verfasserin aut Catherine C Wasmann verfasserin aut Jane Grimwood verfasserin aut Jeremy Schmutz verfasserin aut Masatoki Taga verfasserin aut Gerard J White verfasserin aut Shiguo Zhou verfasserin aut David C Schwartz verfasserin aut Michael Freitag verfasserin aut Li-Jun Ma verfasserin aut Etienne G J Danchin verfasserin aut Bernard Henrissat verfasserin aut Pedro M Coutinho verfasserin aut David R Nelson verfasserin aut Dave Straney verfasserin aut Carolyn A Napoli verfasserin aut Bridget M Barker verfasserin aut Michael Gribskov verfasserin aut Martijn Rep verfasserin aut Scott Kroken verfasserin aut István Molnár verfasserin aut Christopher Rensing verfasserin aut John C Kennell verfasserin aut Jorge Zamora verfasserin aut Mark L Farman verfasserin aut Eric U Selker verfasserin aut Asaf Salamov verfasserin aut Harris Shapiro verfasserin aut Jasmyn Pangilinan verfasserin aut Erika Lindquist verfasserin aut Casey Lamers verfasserin aut Igor V Grigoriev verfasserin aut David M Geiser verfasserin aut Sarah F Covert verfasserin aut Esteban Temporini verfasserin aut Hans D Vanetten verfasserin aut In PLoS Genetics Public Library of Science (PLoS), 2005 5(2009), 8, p e1000618 (DE-627)485248026 (DE-600)2186725-2 15537404 nnns volume:5 year:2009 number:8, p e1000618 https://doi.org/10.1371/journal.pgen.1000618 kostenfrei https://doaj.org/article/82be34517e7a4e04b545733a7dc28bc9 kostenfrei http://europepmc.org/articles/PMC2725324?pdf=render kostenfrei https://doaj.org/toc/1553-7390 Journal toc kostenfrei https://doaj.org/toc/1553-7404 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2031 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2061 GBV_ILN_2111 GBV_ILN_2113 GBV_ILN_2190 GBV_ILN_2522 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 5 2009 8, p e1000618 |
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10.1371/journal.pgen.1000618 doi (DE-627)DOAJ027157342 (DE-599)DOAJ82be34517e7a4e04b545733a7dc28bc9 DE-627 ger DE-627 rakwb eng QH426-470 Jeffrey J Coleman verfasserin aut The genome of Nectria haematococca: contribution of supernumerary chromosomes to gene expansion. 2009 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier The ascomycetous fungus Nectria haematococca, (asexual name Fusarium solani), is a member of a group of <50 species known as the "Fusarium solani species complex". Members of this complex have diverse biological properties including the ability to cause disease on <100 genera of plants and opportunistic infections in humans. The current research analyzed the most extensively studied member of this complex, N. haematococca mating population VI (MPVI). Several genes controlling the ability of individual isolates of this species to colonize specific habitats are located on supernumerary chromosomes. Optical mapping revealed that the sequenced isolate has 17 chromosomes ranging from 530 kb to 6.52 Mb and that the physical size of the genome, 54.43 Mb, and the number of predicted genes, 15,707, are among the largest reported for ascomycetes. Two classes of genes have contributed to gene expansion: specific genes that are not found in other fungi including its closest sequenced relative, Fusarium graminearum; and genes that commonly occur as single copies in other fungi but are present as multiple copies in N. haematococca MPVI. Some of these additional genes appear to have resulted from gene duplication events, while others may have been acquired through horizontal gene transfer. The supernumerary nature of three chromosomes, 14, 15, and 17, was confirmed by their absence in pulsed field gel electrophoresis experiments of some isolates and by demonstrating that these isolates lacked chromosome-specific sequences found on the ends of these chromosomes. These supernumerary chromosomes contain more repeat sequences, are enriched in unique and duplicated genes, and have a lower G+C content in comparison to the other chromosomes. Although the origin(s) of the extra genes and the supernumerary chromosomes is not known, the gene expansion and its large genome size are consistent with this species' diverse range of habitats. Furthermore, the presence of unique genes on supernumerary chromosomes might account for individual isolates having different environmental niches. Genetics Steve D Rounsley verfasserin aut Marianela Rodriguez-Carres verfasserin aut Alan Kuo verfasserin aut Catherine C Wasmann verfasserin aut Jane Grimwood verfasserin aut Jeremy Schmutz verfasserin aut Masatoki Taga verfasserin aut Gerard J White verfasserin aut Shiguo Zhou verfasserin aut David C Schwartz verfasserin aut Michael Freitag verfasserin aut Li-Jun Ma verfasserin aut Etienne G J Danchin verfasserin aut Bernard Henrissat verfasserin aut Pedro M Coutinho verfasserin aut David R Nelson verfasserin aut Dave Straney verfasserin aut Carolyn A Napoli verfasserin aut Bridget M Barker verfasserin aut Michael Gribskov verfasserin aut Martijn Rep verfasserin aut Scott Kroken verfasserin aut István Molnár verfasserin aut Christopher Rensing verfasserin aut John C Kennell verfasserin aut Jorge Zamora verfasserin aut Mark L Farman verfasserin aut Eric U Selker verfasserin aut Asaf Salamov verfasserin aut Harris Shapiro verfasserin aut Jasmyn Pangilinan verfasserin aut Erika Lindquist verfasserin aut Casey Lamers verfasserin aut Igor V Grigoriev verfasserin aut David M Geiser verfasserin aut Sarah F Covert verfasserin aut Esteban Temporini verfasserin aut Hans D Vanetten verfasserin aut In PLoS Genetics Public Library of Science (PLoS), 2005 5(2009), 8, p e1000618 (DE-627)485248026 (DE-600)2186725-2 15537404 nnns volume:5 year:2009 number:8, p e1000618 https://doi.org/10.1371/journal.pgen.1000618 kostenfrei https://doaj.org/article/82be34517e7a4e04b545733a7dc28bc9 kostenfrei http://europepmc.org/articles/PMC2725324?pdf=render kostenfrei https://doaj.org/toc/1553-7390 Journal toc kostenfrei https://doaj.org/toc/1553-7404 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_70 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2031 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2061 GBV_ILN_2111 GBV_ILN_2113 GBV_ILN_2190 GBV_ILN_2522 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 5 2009 8, p e1000618 |
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Jeffrey J Coleman @@aut@@ Steve D Rounsley @@aut@@ Marianela Rodriguez-Carres @@aut@@ Alan Kuo @@aut@@ Catherine C Wasmann @@aut@@ Jane Grimwood @@aut@@ Jeremy Schmutz @@aut@@ Masatoki Taga @@aut@@ Gerard J White @@aut@@ Shiguo Zhou @@aut@@ David C Schwartz @@aut@@ Michael Freitag @@aut@@ Li-Jun Ma @@aut@@ Etienne G J Danchin @@aut@@ Bernard Henrissat @@aut@@ Pedro M Coutinho @@aut@@ David R Nelson @@aut@@ Dave Straney @@aut@@ Carolyn A Napoli @@aut@@ Bridget M Barker @@aut@@ Michael Gribskov @@aut@@ Martijn Rep @@aut@@ Scott Kroken @@aut@@ István Molnár @@aut@@ Christopher Rensing @@aut@@ John C Kennell @@aut@@ Jorge Zamora @@aut@@ Mark L Farman @@aut@@ Eric U Selker @@aut@@ Asaf Salamov @@aut@@ Harris Shapiro @@aut@@ Jasmyn Pangilinan @@aut@@ Erika Lindquist @@aut@@ Casey Lamers @@aut@@ Igor V Grigoriev @@aut@@ David M Geiser @@aut@@ Sarah F Covert @@aut@@ Esteban Temporini @@aut@@ Hans D Vanetten @@aut@@ |
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genome of nectria haematococca: contribution of supernumerary chromosomes to gene expansion |
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The genome of Nectria haematococca: contribution of supernumerary chromosomes to gene expansion. |
| abstract |
The ascomycetous fungus Nectria haematococca, (asexual name Fusarium solani), is a member of a group of <50 species known as the "Fusarium solani species complex". Members of this complex have diverse biological properties including the ability to cause disease on <100 genera of plants and opportunistic infections in humans. The current research analyzed the most extensively studied member of this complex, N. haematococca mating population VI (MPVI). Several genes controlling the ability of individual isolates of this species to colonize specific habitats are located on supernumerary chromosomes. Optical mapping revealed that the sequenced isolate has 17 chromosomes ranging from 530 kb to 6.52 Mb and that the physical size of the genome, 54.43 Mb, and the number of predicted genes, 15,707, are among the largest reported for ascomycetes. Two classes of genes have contributed to gene expansion: specific genes that are not found in other fungi including its closest sequenced relative, Fusarium graminearum; and genes that commonly occur as single copies in other fungi but are present as multiple copies in N. haematococca MPVI. Some of these additional genes appear to have resulted from gene duplication events, while others may have been acquired through horizontal gene transfer. The supernumerary nature of three chromosomes, 14, 15, and 17, was confirmed by their absence in pulsed field gel electrophoresis experiments of some isolates and by demonstrating that these isolates lacked chromosome-specific sequences found on the ends of these chromosomes. These supernumerary chromosomes contain more repeat sequences, are enriched in unique and duplicated genes, and have a lower G+C content in comparison to the other chromosomes. Although the origin(s) of the extra genes and the supernumerary chromosomes is not known, the gene expansion and its large genome size are consistent with this species' diverse range of habitats. Furthermore, the presence of unique genes on supernumerary chromosomes might account for individual isolates having different environmental niches. |
| abstractGer |
The ascomycetous fungus Nectria haematococca, (asexual name Fusarium solani), is a member of a group of <50 species known as the "Fusarium solani species complex". Members of this complex have diverse biological properties including the ability to cause disease on <100 genera of plants and opportunistic infections in humans. The current research analyzed the most extensively studied member of this complex, N. haematococca mating population VI (MPVI). Several genes controlling the ability of individual isolates of this species to colonize specific habitats are located on supernumerary chromosomes. Optical mapping revealed that the sequenced isolate has 17 chromosomes ranging from 530 kb to 6.52 Mb and that the physical size of the genome, 54.43 Mb, and the number of predicted genes, 15,707, are among the largest reported for ascomycetes. Two classes of genes have contributed to gene expansion: specific genes that are not found in other fungi including its closest sequenced relative, Fusarium graminearum; and genes that commonly occur as single copies in other fungi but are present as multiple copies in N. haematococca MPVI. Some of these additional genes appear to have resulted from gene duplication events, while others may have been acquired through horizontal gene transfer. The supernumerary nature of three chromosomes, 14, 15, and 17, was confirmed by their absence in pulsed field gel electrophoresis experiments of some isolates and by demonstrating that these isolates lacked chromosome-specific sequences found on the ends of these chromosomes. These supernumerary chromosomes contain more repeat sequences, are enriched in unique and duplicated genes, and have a lower G+C content in comparison to the other chromosomes. Although the origin(s) of the extra genes and the supernumerary chromosomes is not known, the gene expansion and its large genome size are consistent with this species' diverse range of habitats. Furthermore, the presence of unique genes on supernumerary chromosomes might account for individual isolates having different environmental niches. |
| abstract_unstemmed |
The ascomycetous fungus Nectria haematococca, (asexual name Fusarium solani), is a member of a group of <50 species known as the "Fusarium solani species complex". Members of this complex have diverse biological properties including the ability to cause disease on <100 genera of plants and opportunistic infections in humans. The current research analyzed the most extensively studied member of this complex, N. haematococca mating population VI (MPVI). Several genes controlling the ability of individual isolates of this species to colonize specific habitats are located on supernumerary chromosomes. Optical mapping revealed that the sequenced isolate has 17 chromosomes ranging from 530 kb to 6.52 Mb and that the physical size of the genome, 54.43 Mb, and the number of predicted genes, 15,707, are among the largest reported for ascomycetes. Two classes of genes have contributed to gene expansion: specific genes that are not found in other fungi including its closest sequenced relative, Fusarium graminearum; and genes that commonly occur as single copies in other fungi but are present as multiple copies in N. haematococca MPVI. Some of these additional genes appear to have resulted from gene duplication events, while others may have been acquired through horizontal gene transfer. The supernumerary nature of three chromosomes, 14, 15, and 17, was confirmed by their absence in pulsed field gel electrophoresis experiments of some isolates and by demonstrating that these isolates lacked chromosome-specific sequences found on the ends of these chromosomes. These supernumerary chromosomes contain more repeat sequences, are enriched in unique and duplicated genes, and have a lower G+C content in comparison to the other chromosomes. Although the origin(s) of the extra genes and the supernumerary chromosomes is not known, the gene expansion and its large genome size are consistent with this species' diverse range of habitats. Furthermore, the presence of unique genes on supernumerary chromosomes might account for individual isolates having different environmental niches. |
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<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000caa a22002652 4500</leader><controlfield tag="001">DOAJ027157342</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20230307111644.0</controlfield><controlfield tag="007">cr uuu---uuuuu</controlfield><controlfield tag="008">230226s2009 xx |||||o 00| ||eng c</controlfield><datafield tag="024" ind1="7" ind2=" "><subfield code="a">10.1371/journal.pgen.1000618</subfield><subfield code="2">doi</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)DOAJ027157342</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-599)DOAJ82be34517e7a4e04b545733a7dc28bc9</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="041" ind1=" " ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="050" ind1=" " ind2="0"><subfield code="a">QH426-470</subfield></datafield><datafield tag="100" ind1="0" ind2=" "><subfield code="a">Jeffrey J Coleman</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="4"><subfield code="a">The genome of Nectria haematococca: contribution of supernumerary chromosomes to gene expansion.</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="c">2009</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">Text</subfield><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">Computermedien</subfield><subfield code="b">c</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">Online-Ressource</subfield><subfield code="b">cr</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">The ascomycetous fungus Nectria haematococca, (asexual name Fusarium solani), is a member of a group of <50 species known as the "Fusarium solani species complex". Members of this complex have diverse biological properties including the ability to cause disease on <100 genera of plants and opportunistic infections in humans. The current research analyzed the most extensively studied member of this complex, N. haematococca mating population VI (MPVI). Several genes controlling the ability of individual isolates of this species to colonize specific habitats are located on supernumerary chromosomes. Optical mapping revealed that the sequenced isolate has 17 chromosomes ranging from 530 kb to 6.52 Mb and that the physical size of the genome, 54.43 Mb, and the number of predicted genes, 15,707, are among the largest reported for ascomycetes. Two classes of genes have contributed to gene expansion: specific genes that are not found in other fungi including its closest sequenced relative, Fusarium graminearum; and genes that commonly occur as single copies in other fungi but are present as multiple copies in N. haematococca MPVI. Some of these additional genes appear to have resulted from gene duplication events, while others may have been acquired through horizontal gene transfer. The supernumerary nature of three chromosomes, 14, 15, and 17, was confirmed by their absence in pulsed field gel electrophoresis experiments of some isolates and by demonstrating that these isolates lacked chromosome-specific sequences found on the ends of these chromosomes. These supernumerary chromosomes contain more repeat sequences, are enriched in unique and duplicated genes, and have a lower G+C content in comparison to the other chromosomes. Although the origin(s) of the extra genes and the supernumerary chromosomes is not known, the gene expansion and its large genome size are consistent with this species' diverse range of habitats. 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