Systematic Literature Review of Role of Noroviruses in Sporadic Gastroenteritis

We conducted a systematic review of studies that used reverse transcription–PCR to diagnose norovirus (NoV) infections in patients with mild or moderate (outpatient) and severe (hospitalized) diarrhea. NoVs accounted for 12% (95% confidence interval [CI] 10%–15%) of severe gastroenteritis cases amon...
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Autor*in:	Manish M. Patel [verfasserIn] Marc-Alain Widdowson [verfasserIn] Roger I. Glass [verfasserIn] Kenichiro Akazawa [verfasserIn] Jan Vinjé [verfasserIn] Umesh D. Parashar [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2008

Schlagwörter:	norovirus Norwalk virus calicivirus infections burden of illness diarrhea gastroenteritis

Übergeordnetes Werk:	In: Emerging Infectious Diseases - Centers for Disease Control and Prevention, 2003, 14(2008), 8, Seite 1224-1231
Übergeordnetes Werk:	volume:14 ; year:2008 ; number:8 ; pages:1224-1231

Links:	Link aufrufen Link aufrufen Link aufrufen Journal toc Journal toc

DOI / URN:	10.3201/eid1408.071114

Katalog-ID:	DOAJ02720412X

Internformat


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520			\|a We conducted a systematic review of studies that used reverse transcription–PCR to diagnose norovirus (NoV) infections in patients with mild or moderate (outpatient) and severe (hospitalized) diarrhea. NoVs accounted for 12% (95% confidence interval [CI] 10%–15%) of severe gastroenteritis cases among children <5 years of age and 12% (95% CI 9%–15%) of mild and moderate diarrhea cases among persons of all ages. Of 19 studies among children <5 years of age, 7 were in developing countries where pooled prevalence of severe NoV disease (12%) was comparable to that for industrialized countries (12%). We estimate that each year NoVs cause 64,000 episodes of diarrhea requiring hospitalization and 900,000 clinic visits among children in industrialized countries, and up to 200,000 deaths of children <5 years of age in developing countries. Future efforts should focus on developing targeted strategies, possibly even vaccines, for preventing NoV disease and better documenting their impact among children living in developing countries, where <95% of the deaths from diarrhea occur.
650		4	\|a norovirus
650		4	\|a Norwalk virus
650		4	\|a calicivirus infections
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650		4	\|a diarrhea
650		4	\|a gastroenteritis
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700	0		\|a Marc-Alain Widdowson \|e verfasserin \|4 aut
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700	0		\|a Jan Vinjé \|e verfasserin \|4 aut
700	0		\|a Umesh D. Parashar \|e verfasserin \|4 aut
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912			\|a GBV_ILN_23
912			\|a GBV_ILN_24
912			\|a GBV_ILN_31
912			\|a GBV_ILN_39
912			\|a GBV_ILN_40
912			\|a GBV_ILN_60
912			\|a GBV_ILN_62
912			\|a GBV_ILN_63
912			\|a GBV_ILN_65
912			\|a GBV_ILN_69
912			\|a GBV_ILN_73
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912			\|a GBV_ILN_95
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912			\|a GBV_ILN_170
912			\|a GBV_ILN_206
912			\|a GBV_ILN_213
912			\|a GBV_ILN_224
912			\|a GBV_ILN_230
912			\|a GBV_ILN_252
912			\|a GBV_ILN_285
912			\|a GBV_ILN_293
912			\|a GBV_ILN_602
912			\|a GBV_ILN_702
912			\|a GBV_ILN_2001
912			\|a GBV_ILN_2003
912			\|a GBV_ILN_2005
912			\|a GBV_ILN_2006
912			\|a GBV_ILN_2008
912			\|a GBV_ILN_2009
912			\|a GBV_ILN_2010
912			\|a GBV_ILN_2011
912			\|a GBV_ILN_2014
912			\|a GBV_ILN_2015
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912			\|a GBV_ILN_2050
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912			\|a GBV_ILN_2056
912			\|a GBV_ILN_2057
912			\|a GBV_ILN_2061
912			\|a GBV_ILN_2111
912			\|a GBV_ILN_2113
912			\|a GBV_ILN_2147
912			\|a GBV_ILN_2148
912			\|a GBV_ILN_2153
912			\|a GBV_ILN_2190
912			\|a GBV_ILN_4012
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912			\|a GBV_ILN_4112
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912			\|a GBV_ILN_4307
912			\|a GBV_ILN_4313
912			\|a GBV_ILN_4322
912			\|a GBV_ILN_4323
912			\|a GBV_ILN_4324
912			\|a GBV_ILN_4325
912			\|a GBV_ILN_4338
912			\|a GBV_ILN_4367
912			\|a GBV_ILN_4700
951			\|a AR
952			\|d 14 \|j 2008 \|e 8 \|h 1224-1231

Indexfelder

author_variant	m m p mmp m a w maw r i g rig k a ka j v jv u d p udp
matchkey_str	article:10806059:2008----::ytmtcieaueeiwfoefooiueiso
hierarchy_sort_str	2008
callnumber-subject-code	RC
publishDate	2008
allfields	10.3201/eid1408.071114 doi (DE-627)DOAJ02720412X (DE-599)DOAJa697c40314a246fc958b7b896249e245 DE-627 ger DE-627 rakwb eng RC109-216 Manish M. Patel verfasserin aut Systematic Literature Review of Role of Noroviruses in Sporadic Gastroenteritis 2008 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier We conducted a systematic review of studies that used reverse transcription–PCR to diagnose norovirus (NoV) infections in patients with mild or moderate (outpatient) and severe (hospitalized) diarrhea. NoVs accounted for 12% (95% confidence interval [CI] 10%–15%) of severe gastroenteritis cases among children <5 years of age and 12% (95% CI 9%–15%) of mild and moderate diarrhea cases among persons of all ages. Of 19 studies among children <5 years of age, 7 were in developing countries where pooled prevalence of severe NoV disease (12%) was comparable to that for industrialized countries (12%). We estimate that each year NoVs cause 64,000 episodes of diarrhea requiring hospitalization and 900,000 clinic visits among children in industrialized countries, and up to 200,000 deaths of children <5 years of age in developing countries. Future efforts should focus on developing targeted strategies, possibly even vaccines, for preventing NoV disease and better documenting their impact among children living in developing countries, where <95% of the deaths from diarrhea occur. norovirus Norwalk virus calicivirus infections burden of illness diarrhea gastroenteritis Medicine R Infectious and parasitic diseases Marc-Alain Widdowson verfasserin aut Roger I. Glass verfasserin aut Kenichiro Akazawa verfasserin aut Jan Vinjé verfasserin aut Umesh D. Parashar verfasserin aut In Emerging Infectious Diseases Centers for Disease Control and Prevention, 2003 14(2008), 8, Seite 1224-1231 (DE-627)320436217 (DE-600)2004375-2 10806059 nnns volume:14 year:2008 number:8 pages:1224-1231 https://doi.org/10.3201/eid1408.071114 kostenfrei https://doaj.org/article/a697c40314a246fc958b7b896249e245 kostenfrei https://wwwnc.cdc.gov/eid/article/14/8/07-1114_article kostenfrei https://doaj.org/toc/1080-6040 Journal toc kostenfrei https://doaj.org/toc/1080-6059 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_252 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2031 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2061 GBV_ILN_2111 GBV_ILN_2113 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 14 2008 8 1224-1231
spelling	10.3201/eid1408.071114 doi (DE-627)DOAJ02720412X (DE-599)DOAJa697c40314a246fc958b7b896249e245 DE-627 ger DE-627 rakwb eng RC109-216 Manish M. Patel verfasserin aut Systematic Literature Review of Role of Noroviruses in Sporadic Gastroenteritis 2008 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier We conducted a systematic review of studies that used reverse transcription–PCR to diagnose norovirus (NoV) infections in patients with mild or moderate (outpatient) and severe (hospitalized) diarrhea. NoVs accounted for 12% (95% confidence interval [CI] 10%–15%) of severe gastroenteritis cases among children <5 years of age and 12% (95% CI 9%–15%) of mild and moderate diarrhea cases among persons of all ages. Of 19 studies among children <5 years of age, 7 were in developing countries where pooled prevalence of severe NoV disease (12%) was comparable to that for industrialized countries (12%). We estimate that each year NoVs cause 64,000 episodes of diarrhea requiring hospitalization and 900,000 clinic visits among children in industrialized countries, and up to 200,000 deaths of children <5 years of age in developing countries. Future efforts should focus on developing targeted strategies, possibly even vaccines, for preventing NoV disease and better documenting their impact among children living in developing countries, where <95% of the deaths from diarrhea occur. norovirus Norwalk virus calicivirus infections burden of illness diarrhea gastroenteritis Medicine R Infectious and parasitic diseases Marc-Alain Widdowson verfasserin aut Roger I. Glass verfasserin aut Kenichiro Akazawa verfasserin aut Jan Vinjé verfasserin aut Umesh D. Parashar verfasserin aut In Emerging Infectious Diseases Centers for Disease Control and Prevention, 2003 14(2008), 8, Seite 1224-1231 (DE-627)320436217 (DE-600)2004375-2 10806059 nnns volume:14 year:2008 number:8 pages:1224-1231 https://doi.org/10.3201/eid1408.071114 kostenfrei https://doaj.org/article/a697c40314a246fc958b7b896249e245 kostenfrei https://wwwnc.cdc.gov/eid/article/14/8/07-1114_article kostenfrei https://doaj.org/toc/1080-6040 Journal toc kostenfrei https://doaj.org/toc/1080-6059 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_252 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2031 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2061 GBV_ILN_2111 GBV_ILN_2113 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 14 2008 8 1224-1231
allfields_unstemmed	10.3201/eid1408.071114 doi (DE-627)DOAJ02720412X (DE-599)DOAJa697c40314a246fc958b7b896249e245 DE-627 ger DE-627 rakwb eng RC109-216 Manish M. Patel verfasserin aut Systematic Literature Review of Role of Noroviruses in Sporadic Gastroenteritis 2008 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier We conducted a systematic review of studies that used reverse transcription–PCR to diagnose norovirus (NoV) infections in patients with mild or moderate (outpatient) and severe (hospitalized) diarrhea. NoVs accounted for 12% (95% confidence interval [CI] 10%–15%) of severe gastroenteritis cases among children <5 years of age and 12% (95% CI 9%–15%) of mild and moderate diarrhea cases among persons of all ages. Of 19 studies among children <5 years of age, 7 were in developing countries where pooled prevalence of severe NoV disease (12%) was comparable to that for industrialized countries (12%). We estimate that each year NoVs cause 64,000 episodes of diarrhea requiring hospitalization and 900,000 clinic visits among children in industrialized countries, and up to 200,000 deaths of children <5 years of age in developing countries. Future efforts should focus on developing targeted strategies, possibly even vaccines, for preventing NoV disease and better documenting their impact among children living in developing countries, where <95% of the deaths from diarrhea occur. norovirus Norwalk virus calicivirus infections burden of illness diarrhea gastroenteritis Medicine R Infectious and parasitic diseases Marc-Alain Widdowson verfasserin aut Roger I. Glass verfasserin aut Kenichiro Akazawa verfasserin aut Jan Vinjé verfasserin aut Umesh D. Parashar verfasserin aut In Emerging Infectious Diseases Centers for Disease Control and Prevention, 2003 14(2008), 8, Seite 1224-1231 (DE-627)320436217 (DE-600)2004375-2 10806059 nnns volume:14 year:2008 number:8 pages:1224-1231 https://doi.org/10.3201/eid1408.071114 kostenfrei https://doaj.org/article/a697c40314a246fc958b7b896249e245 kostenfrei https://wwwnc.cdc.gov/eid/article/14/8/07-1114_article kostenfrei https://doaj.org/toc/1080-6040 Journal toc kostenfrei https://doaj.org/toc/1080-6059 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_252 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2031 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2061 GBV_ILN_2111 GBV_ILN_2113 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 14 2008 8 1224-1231
allfieldsGer	10.3201/eid1408.071114 doi (DE-627)DOAJ02720412X (DE-599)DOAJa697c40314a246fc958b7b896249e245 DE-627 ger DE-627 rakwb eng RC109-216 Manish M. Patel verfasserin aut Systematic Literature Review of Role of Noroviruses in Sporadic Gastroenteritis 2008 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier We conducted a systematic review of studies that used reverse transcription–PCR to diagnose norovirus (NoV) infections in patients with mild or moderate (outpatient) and severe (hospitalized) diarrhea. NoVs accounted for 12% (95% confidence interval [CI] 10%–15%) of severe gastroenteritis cases among children <5 years of age and 12% (95% CI 9%–15%) of mild and moderate diarrhea cases among persons of all ages. Of 19 studies among children <5 years of age, 7 were in developing countries where pooled prevalence of severe NoV disease (12%) was comparable to that for industrialized countries (12%). We estimate that each year NoVs cause 64,000 episodes of diarrhea requiring hospitalization and 900,000 clinic visits among children in industrialized countries, and up to 200,000 deaths of children <5 years of age in developing countries. Future efforts should focus on developing targeted strategies, possibly even vaccines, for preventing NoV disease and better documenting their impact among children living in developing countries, where <95% of the deaths from diarrhea occur. norovirus Norwalk virus calicivirus infections burden of illness diarrhea gastroenteritis Medicine R Infectious and parasitic diseases Marc-Alain Widdowson verfasserin aut Roger I. Glass verfasserin aut Kenichiro Akazawa verfasserin aut Jan Vinjé verfasserin aut Umesh D. Parashar verfasserin aut In Emerging Infectious Diseases Centers for Disease Control and Prevention, 2003 14(2008), 8, Seite 1224-1231 (DE-627)320436217 (DE-600)2004375-2 10806059 nnns volume:14 year:2008 number:8 pages:1224-1231 https://doi.org/10.3201/eid1408.071114 kostenfrei https://doaj.org/article/a697c40314a246fc958b7b896249e245 kostenfrei https://wwwnc.cdc.gov/eid/article/14/8/07-1114_article kostenfrei https://doaj.org/toc/1080-6040 Journal toc kostenfrei https://doaj.org/toc/1080-6059 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_252 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2031 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2061 GBV_ILN_2111 GBV_ILN_2113 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 14 2008 8 1224-1231
allfieldsSound	10.3201/eid1408.071114 doi (DE-627)DOAJ02720412X (DE-599)DOAJa697c40314a246fc958b7b896249e245 DE-627 ger DE-627 rakwb eng RC109-216 Manish M. Patel verfasserin aut Systematic Literature Review of Role of Noroviruses in Sporadic Gastroenteritis 2008 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier We conducted a systematic review of studies that used reverse transcription–PCR to diagnose norovirus (NoV) infections in patients with mild or moderate (outpatient) and severe (hospitalized) diarrhea. NoVs accounted for 12% (95% confidence interval [CI] 10%–15%) of severe gastroenteritis cases among children <5 years of age and 12% (95% CI 9%–15%) of mild and moderate diarrhea cases among persons of all ages. Of 19 studies among children <5 years of age, 7 were in developing countries where pooled prevalence of severe NoV disease (12%) was comparable to that for industrialized countries (12%). We estimate that each year NoVs cause 64,000 episodes of diarrhea requiring hospitalization and 900,000 clinic visits among children in industrialized countries, and up to 200,000 deaths of children <5 years of age in developing countries. Future efforts should focus on developing targeted strategies, possibly even vaccines, for preventing NoV disease and better documenting their impact among children living in developing countries, where <95% of the deaths from diarrhea occur. norovirus Norwalk virus calicivirus infections burden of illness diarrhea gastroenteritis Medicine R Infectious and parasitic diseases Marc-Alain Widdowson verfasserin aut Roger I. Glass verfasserin aut Kenichiro Akazawa verfasserin aut Jan Vinjé verfasserin aut Umesh D. Parashar verfasserin aut In Emerging Infectious Diseases Centers for Disease Control and Prevention, 2003 14(2008), 8, Seite 1224-1231 (DE-627)320436217 (DE-600)2004375-2 10806059 nnns volume:14 year:2008 number:8 pages:1224-1231 https://doi.org/10.3201/eid1408.071114 kostenfrei https://doaj.org/article/a697c40314a246fc958b7b896249e245 kostenfrei https://wwwnc.cdc.gov/eid/article/14/8/07-1114_article kostenfrei https://doaj.org/toc/1080-6040 Journal toc kostenfrei https://doaj.org/toc/1080-6059 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ SSG-OLC-PHA GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_252 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_702 GBV_ILN_2001 GBV_ILN_2003 GBV_ILN_2005 GBV_ILN_2006 GBV_ILN_2008 GBV_ILN_2009 GBV_ILN_2010 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2015 GBV_ILN_2020 GBV_ILN_2021 GBV_ILN_2025 GBV_ILN_2031 GBV_ILN_2038 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2050 GBV_ILN_2055 GBV_ILN_2056 GBV_ILN_2057 GBV_ILN_2061 GBV_ILN_2111 GBV_ILN_2113 GBV_ILN_2147 GBV_ILN_2148 GBV_ILN_2153 GBV_ILN_2190 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 14 2008 8 1224-1231
language	English
source	In Emerging Infectious Diseases 14(2008), 8, Seite 1224-1231 volume:14 year:2008 number:8 pages:1224-1231
sourceStr	In Emerging Infectious Diseases 14(2008), 8, Seite 1224-1231 volume:14 year:2008 number:8 pages:1224-1231
format_phy_str_mv	Article
institution	findex.gbv.de
topic_facet	norovirus Norwalk virus calicivirus infections burden of illness diarrhea gastroenteritis Medicine R Infectious and parasitic diseases
isfreeaccess_bool	true
container_title	Emerging Infectious Diseases
authorswithroles_txt_mv	Manish M. Patel @@aut@@ Marc-Alain Widdowson @@aut@@ Roger I. Glass @@aut@@ Kenichiro Akazawa @@aut@@ Jan Vinjé @@aut@@ Umesh D. Parashar @@aut@@
publishDateDaySort_date	2008-01-01T00:00:00Z
hierarchy_top_id	320436217
id	DOAJ02720412X
language_de	englisch
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callnumber-first	R - Medicine
author	Manish M. Patel
spellingShingle	Manish M. Patel misc RC109-216 misc norovirus misc Norwalk virus misc calicivirus infections misc burden of illness misc diarrhea misc gastroenteritis misc Medicine misc R misc Infectious and parasitic diseases Systematic Literature Review of Role of Noroviruses in Sporadic Gastroenteritis
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topic_title	RC109-216 Systematic Literature Review of Role of Noroviruses in Sporadic Gastroenteritis norovirus Norwalk virus calicivirus infections burden of illness diarrhea gastroenteritis
topic	misc RC109-216 misc norovirus misc Norwalk virus misc calicivirus infections misc burden of illness misc diarrhea misc gastroenteritis misc Medicine misc R misc Infectious and parasitic diseases
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title	Systematic Literature Review of Role of Noroviruses in Sporadic Gastroenteritis
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title_full	Systematic Literature Review of Role of Noroviruses in Sporadic Gastroenteritis
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author_browse	Manish M. Patel Marc-Alain Widdowson Roger I. Glass Kenichiro Akazawa Jan Vinjé Umesh D. Parashar
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title_sort	systematic literature review of role of noroviruses in sporadic gastroenteritis
callnumber	RC109-216
title_auth	Systematic Literature Review of Role of Noroviruses in Sporadic Gastroenteritis
abstract	We conducted a systematic review of studies that used reverse transcription–PCR to diagnose norovirus (NoV) infections in patients with mild or moderate (outpatient) and severe (hospitalized) diarrhea. NoVs accounted for 12% (95% confidence interval [CI] 10%–15%) of severe gastroenteritis cases among children <5 years of age and 12% (95% CI 9%–15%) of mild and moderate diarrhea cases among persons of all ages. Of 19 studies among children <5 years of age, 7 were in developing countries where pooled prevalence of severe NoV disease (12%) was comparable to that for industrialized countries (12%). We estimate that each year NoVs cause 64,000 episodes of diarrhea requiring hospitalization and 900,000 clinic visits among children in industrialized countries, and up to 200,000 deaths of children <5 years of age in developing countries. Future efforts should focus on developing targeted strategies, possibly even vaccines, for preventing NoV disease and better documenting their impact among children living in developing countries, where <95% of the deaths from diarrhea occur.
abstractGer	We conducted a systematic review of studies that used reverse transcription–PCR to diagnose norovirus (NoV) infections in patients with mild or moderate (outpatient) and severe (hospitalized) diarrhea. NoVs accounted for 12% (95% confidence interval [CI] 10%–15%) of severe gastroenteritis cases among children <5 years of age and 12% (95% CI 9%–15%) of mild and moderate diarrhea cases among persons of all ages. Of 19 studies among children <5 years of age, 7 were in developing countries where pooled prevalence of severe NoV disease (12%) was comparable to that for industrialized countries (12%). We estimate that each year NoVs cause 64,000 episodes of diarrhea requiring hospitalization and 900,000 clinic visits among children in industrialized countries, and up to 200,000 deaths of children <5 years of age in developing countries. Future efforts should focus on developing targeted strategies, possibly even vaccines, for preventing NoV disease and better documenting their impact among children living in developing countries, where <95% of the deaths from diarrhea occur.
abstract_unstemmed	We conducted a systematic review of studies that used reverse transcription–PCR to diagnose norovirus (NoV) infections in patients with mild or moderate (outpatient) and severe (hospitalized) diarrhea. NoVs accounted for 12% (95% confidence interval [CI] 10%–15%) of severe gastroenteritis cases among children <5 years of age and 12% (95% CI 9%–15%) of mild and moderate diarrhea cases among persons of all ages. Of 19 studies among children <5 years of age, 7 were in developing countries where pooled prevalence of severe NoV disease (12%) was comparable to that for industrialized countries (12%). We estimate that each year NoVs cause 64,000 episodes of diarrhea requiring hospitalization and 900,000 clinic visits among children in industrialized countries, and up to 200,000 deaths of children <5 years of age in developing countries. Future efforts should focus on developing targeted strategies, possibly even vaccines, for preventing NoV disease and better documenting their impact among children living in developing countries, where <95% of the deaths from diarrhea occur.
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title_short	Systematic Literature Review of Role of Noroviruses in Sporadic Gastroenteritis
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author2	Marc-Alain Widdowson Roger I. Glass Kenichiro Akazawa Jan Vinjé Umesh D. Parashar
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Systematic Literature Review of Role of Noroviruses in Sporadic Gastroenteritis

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