Osteopontin in chronic obstructive pulmonary disease: Smokers and ex-smokers

Background: COPD is a widely distributed disease with high morbidity and mortality, associated with different pathologies. The link between osteopontin, smoking and COPD needs to be clarified. Objectives: To study the osteopontin serum levels in smoker COPD patients and ex-smoker COPD patients. Meth...
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Autor*in:	Ahmed A Ali [verfasserIn] Nourane Y. Azab [verfasserIn] Ibrahim I. El-Mahalawy [verfasserIn] Safaa I. Tayel [verfasserIn] Ehab M. Khalifa [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2015

Schlagwörter:	Osteopontin Smokers Ex-smokers COPD

Übergeordnetes Werk:	In: Egyptian Journal of Chest Disease and Tuberculosis - Wolters Kluwer Medknow Publications, 2016, 64(2015), 1, Seite 63-66
Übergeordnetes Werk:	volume:64 ; year:2015 ; number:1 ; pages:63-66

Links:	Link aufrufen Link aufrufen Link aufrufen Journal toc

DOI / URN:	10.1016/j.ejcdt.2014.11.009

Katalog-ID:	DOAJ027627314

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520			\|a Background: COPD is a widely distributed disease with high morbidity and mortality, associated with different pathologies. The link between osteopontin, smoking and COPD needs to be clarified. Objectives: To study the osteopontin serum levels in smoker COPD patients and ex-smoker COPD patients. Methods: Serum levels of osteopontin were measured in 38 male COPD patients divided into smoker and ex-smoker groups using human osteopontin ELISA kits. Results: There was a significant difference between smokers and ex-smokers regarding their serum osteopontin levels. There was no significant difference in serum osteopontin level between COPD patients regarding severity in both groups. There was a significant difference in serum osteopontin level between the smokers group regarding their pack year index of smoking. There was no significant difference in serum osteopontin level between ex-smokers group regarding the duration of cessation. Conclusion: Serum level of osteopontin is increased in COPD patients and decreases with cessation of smoking. It has no relation to disease severity.
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allfields	10.1016/j.ejcdt.2014.11.009 doi (DE-627)DOAJ027627314 (DE-599)DOAJ50446ac2e92e41778ad82a9acef19ea6 DE-627 ger DE-627 rakwb eng RC705-779 Ahmed A Ali verfasserin aut Osteopontin in chronic obstructive pulmonary disease: Smokers and ex-smokers 2015 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background: COPD is a widely distributed disease with high morbidity and mortality, associated with different pathologies. The link between osteopontin, smoking and COPD needs to be clarified. Objectives: To study the osteopontin serum levels in smoker COPD patients and ex-smoker COPD patients. Methods: Serum levels of osteopontin were measured in 38 male COPD patients divided into smoker and ex-smoker groups using human osteopontin ELISA kits. Results: There was a significant difference between smokers and ex-smokers regarding their serum osteopontin levels. There was no significant difference in serum osteopontin level between COPD patients regarding severity in both groups. There was a significant difference in serum osteopontin level between the smokers group regarding their pack year index of smoking. There was no significant difference in serum osteopontin level between ex-smokers group regarding the duration of cessation. Conclusion: Serum level of osteopontin is increased in COPD patients and decreases with cessation of smoking. It has no relation to disease severity. Osteopontin Smokers Ex-smokers COPD Diseases of the respiratory system Nourane Y. Azab verfasserin aut Ibrahim I. El-Mahalawy verfasserin aut Safaa I. Tayel verfasserin aut Ehab M. Khalifa verfasserin aut In Egyptian Journal of Chest Disease and Tuberculosis Wolters Kluwer Medknow Publications, 2016 64(2015), 1, Seite 63-66 (DE-627)820688878 (DE-600)2814778-9 20909950 nnns volume:64 year:2015 number:1 pages:63-66 https://doi.org/10.1016/j.ejcdt.2014.11.009 kostenfrei https://doaj.org/article/50446ac2e92e41778ad82a9acef19ea6 kostenfrei http://www.sciencedirect.com/science/article/pii/S0422763814200550 kostenfrei https://doaj.org/toc/0422-7638 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 64 2015 1 63-66
spelling	10.1016/j.ejcdt.2014.11.009 doi (DE-627)DOAJ027627314 (DE-599)DOAJ50446ac2e92e41778ad82a9acef19ea6 DE-627 ger DE-627 rakwb eng RC705-779 Ahmed A Ali verfasserin aut Osteopontin in chronic obstructive pulmonary disease: Smokers and ex-smokers 2015 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background: COPD is a widely distributed disease with high morbidity and mortality, associated with different pathologies. The link between osteopontin, smoking and COPD needs to be clarified. Objectives: To study the osteopontin serum levels in smoker COPD patients and ex-smoker COPD patients. Methods: Serum levels of osteopontin were measured in 38 male COPD patients divided into smoker and ex-smoker groups using human osteopontin ELISA kits. Results: There was a significant difference between smokers and ex-smokers regarding their serum osteopontin levels. There was no significant difference in serum osteopontin level between COPD patients regarding severity in both groups. There was a significant difference in serum osteopontin level between the smokers group regarding their pack year index of smoking. There was no significant difference in serum osteopontin level between ex-smokers group regarding the duration of cessation. Conclusion: Serum level of osteopontin is increased in COPD patients and decreases with cessation of smoking. It has no relation to disease severity. Osteopontin Smokers Ex-smokers COPD Diseases of the respiratory system Nourane Y. Azab verfasserin aut Ibrahim I. El-Mahalawy verfasserin aut Safaa I. Tayel verfasserin aut Ehab M. Khalifa verfasserin aut In Egyptian Journal of Chest Disease and Tuberculosis Wolters Kluwer Medknow Publications, 2016 64(2015), 1, Seite 63-66 (DE-627)820688878 (DE-600)2814778-9 20909950 nnns volume:64 year:2015 number:1 pages:63-66 https://doi.org/10.1016/j.ejcdt.2014.11.009 kostenfrei https://doaj.org/article/50446ac2e92e41778ad82a9acef19ea6 kostenfrei http://www.sciencedirect.com/science/article/pii/S0422763814200550 kostenfrei https://doaj.org/toc/0422-7638 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 64 2015 1 63-66
allfields_unstemmed	10.1016/j.ejcdt.2014.11.009 doi (DE-627)DOAJ027627314 (DE-599)DOAJ50446ac2e92e41778ad82a9acef19ea6 DE-627 ger DE-627 rakwb eng RC705-779 Ahmed A Ali verfasserin aut Osteopontin in chronic obstructive pulmonary disease: Smokers and ex-smokers 2015 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background: COPD is a widely distributed disease with high morbidity and mortality, associated with different pathologies. The link between osteopontin, smoking and COPD needs to be clarified. Objectives: To study the osteopontin serum levels in smoker COPD patients and ex-smoker COPD patients. Methods: Serum levels of osteopontin were measured in 38 male COPD patients divided into smoker and ex-smoker groups using human osteopontin ELISA kits. Results: There was a significant difference between smokers and ex-smokers regarding their serum osteopontin levels. There was no significant difference in serum osteopontin level between COPD patients regarding severity in both groups. There was a significant difference in serum osteopontin level between the smokers group regarding their pack year index of smoking. There was no significant difference in serum osteopontin level between ex-smokers group regarding the duration of cessation. Conclusion: Serum level of osteopontin is increased in COPD patients and decreases with cessation of smoking. It has no relation to disease severity. Osteopontin Smokers Ex-smokers COPD Diseases of the respiratory system Nourane Y. Azab verfasserin aut Ibrahim I. El-Mahalawy verfasserin aut Safaa I. Tayel verfasserin aut Ehab M. Khalifa verfasserin aut In Egyptian Journal of Chest Disease and Tuberculosis Wolters Kluwer Medknow Publications, 2016 64(2015), 1, Seite 63-66 (DE-627)820688878 (DE-600)2814778-9 20909950 nnns volume:64 year:2015 number:1 pages:63-66 https://doi.org/10.1016/j.ejcdt.2014.11.009 kostenfrei https://doaj.org/article/50446ac2e92e41778ad82a9acef19ea6 kostenfrei http://www.sciencedirect.com/science/article/pii/S0422763814200550 kostenfrei https://doaj.org/toc/0422-7638 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 64 2015 1 63-66
allfieldsGer	10.1016/j.ejcdt.2014.11.009 doi (DE-627)DOAJ027627314 (DE-599)DOAJ50446ac2e92e41778ad82a9acef19ea6 DE-627 ger DE-627 rakwb eng RC705-779 Ahmed A Ali verfasserin aut Osteopontin in chronic obstructive pulmonary disease: Smokers and ex-smokers 2015 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background: COPD is a widely distributed disease with high morbidity and mortality, associated with different pathologies. The link between osteopontin, smoking and COPD needs to be clarified. Objectives: To study the osteopontin serum levels in smoker COPD patients and ex-smoker COPD patients. Methods: Serum levels of osteopontin were measured in 38 male COPD patients divided into smoker and ex-smoker groups using human osteopontin ELISA kits. Results: There was a significant difference between smokers and ex-smokers regarding their serum osteopontin levels. There was no significant difference in serum osteopontin level between COPD patients regarding severity in both groups. There was a significant difference in serum osteopontin level between the smokers group regarding their pack year index of smoking. There was no significant difference in serum osteopontin level between ex-smokers group regarding the duration of cessation. Conclusion: Serum level of osteopontin is increased in COPD patients and decreases with cessation of smoking. It has no relation to disease severity. Osteopontin Smokers Ex-smokers COPD Diseases of the respiratory system Nourane Y. Azab verfasserin aut Ibrahim I. El-Mahalawy verfasserin aut Safaa I. Tayel verfasserin aut Ehab M. Khalifa verfasserin aut In Egyptian Journal of Chest Disease and Tuberculosis Wolters Kluwer Medknow Publications, 2016 64(2015), 1, Seite 63-66 (DE-627)820688878 (DE-600)2814778-9 20909950 nnns volume:64 year:2015 number:1 pages:63-66 https://doi.org/10.1016/j.ejcdt.2014.11.009 kostenfrei https://doaj.org/article/50446ac2e92e41778ad82a9acef19ea6 kostenfrei http://www.sciencedirect.com/science/article/pii/S0422763814200550 kostenfrei https://doaj.org/toc/0422-7638 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 64 2015 1 63-66
allfieldsSound	10.1016/j.ejcdt.2014.11.009 doi (DE-627)DOAJ027627314 (DE-599)DOAJ50446ac2e92e41778ad82a9acef19ea6 DE-627 ger DE-627 rakwb eng RC705-779 Ahmed A Ali verfasserin aut Osteopontin in chronic obstructive pulmonary disease: Smokers and ex-smokers 2015 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background: COPD is a widely distributed disease with high morbidity and mortality, associated with different pathologies. The link between osteopontin, smoking and COPD needs to be clarified. Objectives: To study the osteopontin serum levels in smoker COPD patients and ex-smoker COPD patients. Methods: Serum levels of osteopontin were measured in 38 male COPD patients divided into smoker and ex-smoker groups using human osteopontin ELISA kits. Results: There was a significant difference between smokers and ex-smokers regarding their serum osteopontin levels. There was no significant difference in serum osteopontin level between COPD patients regarding severity in both groups. There was a significant difference in serum osteopontin level between the smokers group regarding their pack year index of smoking. There was no significant difference in serum osteopontin level between ex-smokers group regarding the duration of cessation. Conclusion: Serum level of osteopontin is increased in COPD patients and decreases with cessation of smoking. It has no relation to disease severity. Osteopontin Smokers Ex-smokers COPD Diseases of the respiratory system Nourane Y. Azab verfasserin aut Ibrahim I. El-Mahalawy verfasserin aut Safaa I. Tayel verfasserin aut Ehab M. Khalifa verfasserin aut In Egyptian Journal of Chest Disease and Tuberculosis Wolters Kluwer Medknow Publications, 2016 64(2015), 1, Seite 63-66 (DE-627)820688878 (DE-600)2814778-9 20909950 nnns volume:64 year:2015 number:1 pages:63-66 https://doi.org/10.1016/j.ejcdt.2014.11.009 kostenfrei https://doaj.org/article/50446ac2e92e41778ad82a9acef19ea6 kostenfrei http://www.sciencedirect.com/science/article/pii/S0422763814200550 kostenfrei https://doaj.org/toc/0422-7638 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 64 2015 1 63-66
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source	In Egyptian Journal of Chest Disease and Tuberculosis 64(2015), 1, Seite 63-66 volume:64 year:2015 number:1 pages:63-66
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authorswithroles_txt_mv	Ahmed A Ali @@aut@@ Nourane Y. Azab @@aut@@ Ibrahim I. El-Mahalawy @@aut@@ Safaa I. Tayel @@aut@@ Ehab M. Khalifa @@aut@@
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callnumber-first	R - Medicine
author	Ahmed A Ali
spellingShingle	Ahmed A Ali misc RC705-779 misc Osteopontin misc Smokers misc Ex-smokers misc COPD misc Diseases of the respiratory system Osteopontin in chronic obstructive pulmonary disease: Smokers and ex-smokers
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topic_title	RC705-779 Osteopontin in chronic obstructive pulmonary disease: Smokers and ex-smokers Osteopontin Smokers Ex-smokers COPD
topic	misc RC705-779 misc Osteopontin misc Smokers misc Ex-smokers misc COPD misc Diseases of the respiratory system
topic_unstemmed	misc RC705-779 misc Osteopontin misc Smokers misc Ex-smokers misc COPD misc Diseases of the respiratory system
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title	Osteopontin in chronic obstructive pulmonary disease: Smokers and ex-smokers
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title_full	Osteopontin in chronic obstructive pulmonary disease: Smokers and ex-smokers
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journal	Egyptian Journal of Chest Disease and Tuberculosis
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author_browse	Ahmed A Ali Nourane Y. Azab Ibrahim I. El-Mahalawy Safaa I. Tayel Ehab M. Khalifa
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title_sort	osteopontin in chronic obstructive pulmonary disease: smokers and ex-smokers
callnumber	RC705-779
title_auth	Osteopontin in chronic obstructive pulmonary disease: Smokers and ex-smokers
abstract	Background: COPD is a widely distributed disease with high morbidity and mortality, associated with different pathologies. The link between osteopontin, smoking and COPD needs to be clarified. Objectives: To study the osteopontin serum levels in smoker COPD patients and ex-smoker COPD patients. Methods: Serum levels of osteopontin were measured in 38 male COPD patients divided into smoker and ex-smoker groups using human osteopontin ELISA kits. Results: There was a significant difference between smokers and ex-smokers regarding their serum osteopontin levels. There was no significant difference in serum osteopontin level between COPD patients regarding severity in both groups. There was a significant difference in serum osteopontin level between the smokers group regarding their pack year index of smoking. There was no significant difference in serum osteopontin level between ex-smokers group regarding the duration of cessation. Conclusion: Serum level of osteopontin is increased in COPD patients and decreases with cessation of smoking. It has no relation to disease severity.
abstractGer	Background: COPD is a widely distributed disease with high morbidity and mortality, associated with different pathologies. The link between osteopontin, smoking and COPD needs to be clarified. Objectives: To study the osteopontin serum levels in smoker COPD patients and ex-smoker COPD patients. Methods: Serum levels of osteopontin were measured in 38 male COPD patients divided into smoker and ex-smoker groups using human osteopontin ELISA kits. Results: There was a significant difference between smokers and ex-smokers regarding their serum osteopontin levels. There was no significant difference in serum osteopontin level between COPD patients regarding severity in both groups. There was a significant difference in serum osteopontin level between the smokers group regarding their pack year index of smoking. There was no significant difference in serum osteopontin level between ex-smokers group regarding the duration of cessation. Conclusion: Serum level of osteopontin is increased in COPD patients and decreases with cessation of smoking. It has no relation to disease severity.
abstract_unstemmed	Background: COPD is a widely distributed disease with high morbidity and mortality, associated with different pathologies. The link between osteopontin, smoking and COPD needs to be clarified. Objectives: To study the osteopontin serum levels in smoker COPD patients and ex-smoker COPD patients. Methods: Serum levels of osteopontin were measured in 38 male COPD patients divided into smoker and ex-smoker groups using human osteopontin ELISA kits. Results: There was a significant difference between smokers and ex-smokers regarding their serum osteopontin levels. There was no significant difference in serum osteopontin level between COPD patients regarding severity in both groups. There was a significant difference in serum osteopontin level between the smokers group regarding their pack year index of smoking. There was no significant difference in serum osteopontin level between ex-smokers group regarding the duration of cessation. Conclusion: Serum level of osteopontin is increased in COPD patients and decreases with cessation of smoking. It has no relation to disease severity.
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title_short	Osteopontin in chronic obstructive pulmonary disease: Smokers and ex-smokers
url	https://doi.org/10.1016/j.ejcdt.2014.11.009 https://doaj.org/article/50446ac2e92e41778ad82a9acef19ea6 http://www.sciencedirect.com/science/article/pii/S0422763814200550 https://doaj.org/toc/0422-7638
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author2	Nourane Y. Azab Ibrahim I. El-Mahalawy Safaa I. Tayel Ehab M. Khalifa
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up_date	2024-07-04T02:23:11.914Z
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