Influence of maternal obesity on the multi-omics profiles of the maternal body, gestational tissue, and offspring

Epidemiological studies show that obesity during pregnancy affects more than half of the pregnancies in the developed countries and is associated with obstetric problems and poor outcomes. Obesity tends to increase the incidence of complications. Furthermore, the resulting offspring are also adverse...
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Gespeichert in:

Autor*in:	Duan Zhao [verfasserIn] Yusi Liu [verfasserIn] Shanshan Jia [verfasserIn] Yiwen He [verfasserIn] Xiaowei Wei [verfasserIn] Dan Liu [verfasserIn] Wei Ma [verfasserIn] Wenting Luo [verfasserIn] Hui Gu [verfasserIn] Zhengwei Yuan [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2022

Schlagwörter:	Maternal obesity Offspring Epigenetics Transcriptomics Proteomics Metabolomics

Übergeordnetes Werk:	In: Biomedicine & Pharmacotherapy - Elsevier, 2021, 151(2022), Seite 113103-
Übergeordnetes Werk:	volume:151 ; year:2022 ; pages:113103-

Links:	Link aufrufen Link aufrufen Link aufrufen Journal toc

DOI / URN:	10.1016/j.biopha.2022.113103

Katalog-ID:	DOAJ027882187

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650		4	\|a Maternal obesity
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650		4	\|a Epigenetics
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allfieldsSound	10.1016/j.biopha.2022.113103 doi (DE-627)DOAJ027882187 (DE-599)DOAJ37209153ea614586878302873aa9dbf9 DE-627 ger DE-627 rakwb eng RM1-950 Duan Zhao verfasserin aut Influence of maternal obesity on the multi-omics profiles of the maternal body, gestational tissue, and offspring 2022 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Epidemiological studies show that obesity during pregnancy affects more than half of the pregnancies in the developed countries and is associated with obstetric problems and poor outcomes. Obesity tends to increase the incidence of complications. Furthermore, the resulting offspring are also adversely affected. However, the molecular mechanisms of obesity leading to poor pregnancy outcomes remain unclear. Omics methods are used for genetic diagnosis and marker discovery. The aim of this review was to summarize the maternal and fetal pathophysiological alterations induced by gestational obesity,identified using multi-omics detection techniques, and to generalize the biological functions and potential mechanisms of the differentially expressed molecules. Maternal obesity Offspring Epigenetics Transcriptomics Proteomics Metabolomics Therapeutics. Pharmacology Yusi Liu verfasserin aut Shanshan Jia verfasserin aut Yiwen He verfasserin aut Xiaowei Wei verfasserin aut Dan Liu verfasserin aut Wei Ma verfasserin aut Wenting Luo verfasserin aut Hui Gu verfasserin aut Zhengwei Yuan verfasserin aut In Biomedicine & Pharmacotherapy Elsevier, 2021 151(2022), Seite 113103- (DE-627)306717565 (DE-600)1501510-5 19506007 nnns volume:151 year:2022 pages:113103- https://doi.org/10.1016/j.biopha.2022.113103 kostenfrei https://doaj.org/article/37209153ea614586878302873aa9dbf9 kostenfrei http://www.sciencedirect.com/science/article/pii/S0753332222004929 kostenfrei https://doaj.org/toc/0753-3322 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_165 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_224 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2004 GBV_ILN_2005 GBV_ILN_2008 GBV_ILN_2014 GBV_ILN_2025 GBV_ILN_2034 GBV_ILN_2044 GBV_ILN_2048 GBV_ILN_2064 GBV_ILN_2106 GBV_ILN_2111 GBV_ILN_2112 GBV_ILN_2122 GBV_ILN_2143 GBV_ILN_2152 GBV_ILN_2153 GBV_ILN_2232 GBV_ILN_2336 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4251 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 151 2022 113103-
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callnumber-first	R - Medicine
author	Duan Zhao
spellingShingle	Duan Zhao misc RM1-950 misc Maternal obesity misc Offspring misc Epigenetics misc Transcriptomics misc Proteomics misc Metabolomics misc Therapeutics. Pharmacology Influence of maternal obesity on the multi-omics profiles of the maternal body, gestational tissue, and offspring
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topic_title	RM1-950 Influence of maternal obesity on the multi-omics profiles of the maternal body, gestational tissue, and offspring Maternal obesity Offspring Epigenetics Transcriptomics Proteomics Metabolomics
topic	misc RM1-950 misc Maternal obesity misc Offspring misc Epigenetics misc Transcriptomics misc Proteomics misc Metabolomics misc Therapeutics. Pharmacology
topic_unstemmed	misc RM1-950 misc Maternal obesity misc Offspring misc Epigenetics misc Transcriptomics misc Proteomics misc Metabolomics misc Therapeutics. Pharmacology
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title	Influence of maternal obesity on the multi-omics profiles of the maternal body, gestational tissue, and offspring
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title_full	Influence of maternal obesity on the multi-omics profiles of the maternal body, gestational tissue, and offspring
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author_browse	Duan Zhao Yusi Liu Shanshan Jia Yiwen He Xiaowei Wei Dan Liu Wei Ma Wenting Luo Hui Gu Zhengwei Yuan
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title_sort	influence of maternal obesity on the multi-omics profiles of the maternal body, gestational tissue, and offspring
callnumber	RM1-950
title_auth	Influence of maternal obesity on the multi-omics profiles of the maternal body, gestational tissue, and offspring
abstract	Epidemiological studies show that obesity during pregnancy affects more than half of the pregnancies in the developed countries and is associated with obstetric problems and poor outcomes. Obesity tends to increase the incidence of complications. Furthermore, the resulting offspring are also adversely affected. However, the molecular mechanisms of obesity leading to poor pregnancy outcomes remain unclear. Omics methods are used for genetic diagnosis and marker discovery. The aim of this review was to summarize the maternal and fetal pathophysiological alterations induced by gestational obesity,identified using multi-omics detection techniques, and to generalize the biological functions and potential mechanisms of the differentially expressed molecules.
abstractGer	Epidemiological studies show that obesity during pregnancy affects more than half of the pregnancies in the developed countries and is associated with obstetric problems and poor outcomes. Obesity tends to increase the incidence of complications. Furthermore, the resulting offspring are also adversely affected. However, the molecular mechanisms of obesity leading to poor pregnancy outcomes remain unclear. Omics methods are used for genetic diagnosis and marker discovery. The aim of this review was to summarize the maternal and fetal pathophysiological alterations induced by gestational obesity,identified using multi-omics detection techniques, and to generalize the biological functions and potential mechanisms of the differentially expressed molecules.
abstract_unstemmed	Epidemiological studies show that obesity during pregnancy affects more than half of the pregnancies in the developed countries and is associated with obstetric problems and poor outcomes. Obesity tends to increase the incidence of complications. Furthermore, the resulting offspring are also adversely affected. However, the molecular mechanisms of obesity leading to poor pregnancy outcomes remain unclear. Omics methods are used for genetic diagnosis and marker discovery. The aim of this review was to summarize the maternal and fetal pathophysiological alterations induced by gestational obesity,identified using multi-omics detection techniques, and to generalize the biological functions and potential mechanisms of the differentially expressed molecules.
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title_short	Influence of maternal obesity on the multi-omics profiles of the maternal body, gestational tissue, and offspring
url	https://doi.org/10.1016/j.biopha.2022.113103 https://doaj.org/article/37209153ea614586878302873aa9dbf9 http://www.sciencedirect.com/science/article/pii/S0753332222004929 https://doaj.org/toc/0753-3322
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up_date	2024-07-03T14:33:06.259Z
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Influence of maternal obesity on the multi-omics profiles of the maternal body, gestational tissue, and offspring

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