Clinical features and histological patterns of lupus nephritis in Eastern Nepal

To determine the clinical profile and patterns of lupus nephritis patients in Eastern Nepal, we studied 38 patients fulfilling the 1982 revised criteria of American College of Rheu-matology for systemic lupus erythematous (SLE), followed up from January 2004 to January 2008. Arthritis was a common i...
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Autor*in:	Subodh Sagar Dhakal [verfasserIn] Sanjib Kumar Sharma [verfasserIn] Narendra Bhatta [verfasserIn] Sabina Bhattarai [verfasserIn] Smriti Karki [verfasserIn] Shailendra Shrestha [verfasserIn] Suman Rijal [verfasserIn] Prahlad Karkil [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2011

Übergeordnetes Werk:	In: Saudi Journal of Kidney Diseases and Transplantation - Wolters Kluwer Medknow Publications, 2007, 22(2011), 2, Seite 377-380
Übergeordnetes Werk:	volume:22 ; year:2011 ; number:2 ; pages:377-380

Links:	Link aufrufen Link aufrufen Journal toc

Katalog-ID:	DOAJ027981983

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allfields	(DE-627)DOAJ027981983 (DE-599)DOAJde5f31a0cd2148a0966bded0605ce61e DE-627 ger DE-627 rakwb eng Subodh Sagar Dhakal verfasserin aut Clinical features and histological patterns of lupus nephritis in Eastern Nepal 2011 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier To determine the clinical profile and patterns of lupus nephritis patients in Eastern Nepal, we studied 38 patients fulfilling the 1982 revised criteria of American College of Rheu-matology for systemic lupus erythematous (SLE), followed up from January 2004 to January 2008. Arthritis was a common initial feature in addition to variable cutaneous, cardiac, pulmonary and neuropsychiatric manifestations. Renal biopsy showed grade 1 changes in 5 (13.5%) patients, grade 2 changes in 13 (35.1%) patients, grade 3 changes in 9 (24.3%) patients, grade 4 changes in 7 (18.9%) patients, grade 5 changes in 2 (5.4%) patients, and grade 6 changes in 2.7% patients. Antinuclear antibody (ANA) assay and anti-ds DNA were positive in 78.4 and 81.1%, respec-tively. We conclude that mesangial proliferative glomerulonephritis (grade 2) was the most common pattern of lupus nephritis encountered in our study. Timely diagnosis and treatment may improve the overall patients′ survival. Medicine R Sanjib Kumar Sharma verfasserin aut Narendra Bhatta verfasserin aut Sabina Bhattarai verfasserin aut Smriti Karki verfasserin aut Shailendra Shrestha verfasserin aut Suman Rijal verfasserin aut Prahlad Karkil verfasserin aut In Saudi Journal of Kidney Diseases and Transplantation Wolters Kluwer Medknow Publications, 2007 22(2011), 2, Seite 377-380 (DE-627)613740475 (DE-600)2526321-3 23203838 nnns volume:22 year:2011 number:2 pages:377-380 https://doaj.org/article/de5f31a0cd2148a0966bded0605ce61e kostenfrei http://www.sjkdt.org/article.asp?issn=1319-2442;year=2011;volume=22;issue=2;spage=377;epage=380;aulast=Dhakal kostenfrei https://doaj.org/toc/1319-2442 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 22 2011 2 377-380
spelling	(DE-627)DOAJ027981983 (DE-599)DOAJde5f31a0cd2148a0966bded0605ce61e DE-627 ger DE-627 rakwb eng Subodh Sagar Dhakal verfasserin aut Clinical features and histological patterns of lupus nephritis in Eastern Nepal 2011 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier To determine the clinical profile and patterns of lupus nephritis patients in Eastern Nepal, we studied 38 patients fulfilling the 1982 revised criteria of American College of Rheu-matology for systemic lupus erythematous (SLE), followed up from January 2004 to January 2008. Arthritis was a common initial feature in addition to variable cutaneous, cardiac, pulmonary and neuropsychiatric manifestations. Renal biopsy showed grade 1 changes in 5 (13.5%) patients, grade 2 changes in 13 (35.1%) patients, grade 3 changes in 9 (24.3%) patients, grade 4 changes in 7 (18.9%) patients, grade 5 changes in 2 (5.4%) patients, and grade 6 changes in 2.7% patients. Antinuclear antibody (ANA) assay and anti-ds DNA were positive in 78.4 and 81.1%, respec-tively. We conclude that mesangial proliferative glomerulonephritis (grade 2) was the most common pattern of lupus nephritis encountered in our study. Timely diagnosis and treatment may improve the overall patients′ survival. Medicine R Sanjib Kumar Sharma verfasserin aut Narendra Bhatta verfasserin aut Sabina Bhattarai verfasserin aut Smriti Karki verfasserin aut Shailendra Shrestha verfasserin aut Suman Rijal verfasserin aut Prahlad Karkil verfasserin aut In Saudi Journal of Kidney Diseases and Transplantation Wolters Kluwer Medknow Publications, 2007 22(2011), 2, Seite 377-380 (DE-627)613740475 (DE-600)2526321-3 23203838 nnns volume:22 year:2011 number:2 pages:377-380 https://doaj.org/article/de5f31a0cd2148a0966bded0605ce61e kostenfrei http://www.sjkdt.org/article.asp?issn=1319-2442;year=2011;volume=22;issue=2;spage=377;epage=380;aulast=Dhakal kostenfrei https://doaj.org/toc/1319-2442 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 22 2011 2 377-380
allfields_unstemmed	(DE-627)DOAJ027981983 (DE-599)DOAJde5f31a0cd2148a0966bded0605ce61e DE-627 ger DE-627 rakwb eng Subodh Sagar Dhakal verfasserin aut Clinical features and histological patterns of lupus nephritis in Eastern Nepal 2011 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier To determine the clinical profile and patterns of lupus nephritis patients in Eastern Nepal, we studied 38 patients fulfilling the 1982 revised criteria of American College of Rheu-matology for systemic lupus erythematous (SLE), followed up from January 2004 to January 2008. Arthritis was a common initial feature in addition to variable cutaneous, cardiac, pulmonary and neuropsychiatric manifestations. Renal biopsy showed grade 1 changes in 5 (13.5%) patients, grade 2 changes in 13 (35.1%) patients, grade 3 changes in 9 (24.3%) patients, grade 4 changes in 7 (18.9%) patients, grade 5 changes in 2 (5.4%) patients, and grade 6 changes in 2.7% patients. Antinuclear antibody (ANA) assay and anti-ds DNA were positive in 78.4 and 81.1%, respec-tively. We conclude that mesangial proliferative glomerulonephritis (grade 2) was the most common pattern of lupus nephritis encountered in our study. Timely diagnosis and treatment may improve the overall patients′ survival. Medicine R Sanjib Kumar Sharma verfasserin aut Narendra Bhatta verfasserin aut Sabina Bhattarai verfasserin aut Smriti Karki verfasserin aut Shailendra Shrestha verfasserin aut Suman Rijal verfasserin aut Prahlad Karkil verfasserin aut In Saudi Journal of Kidney Diseases and Transplantation Wolters Kluwer Medknow Publications, 2007 22(2011), 2, Seite 377-380 (DE-627)613740475 (DE-600)2526321-3 23203838 nnns volume:22 year:2011 number:2 pages:377-380 https://doaj.org/article/de5f31a0cd2148a0966bded0605ce61e kostenfrei http://www.sjkdt.org/article.asp?issn=1319-2442;year=2011;volume=22;issue=2;spage=377;epage=380;aulast=Dhakal kostenfrei https://doaj.org/toc/1319-2442 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 22 2011 2 377-380
allfieldsGer	(DE-627)DOAJ027981983 (DE-599)DOAJde5f31a0cd2148a0966bded0605ce61e DE-627 ger DE-627 rakwb eng Subodh Sagar Dhakal verfasserin aut Clinical features and histological patterns of lupus nephritis in Eastern Nepal 2011 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier To determine the clinical profile and patterns of lupus nephritis patients in Eastern Nepal, we studied 38 patients fulfilling the 1982 revised criteria of American College of Rheu-matology for systemic lupus erythematous (SLE), followed up from January 2004 to January 2008. Arthritis was a common initial feature in addition to variable cutaneous, cardiac, pulmonary and neuropsychiatric manifestations. Renal biopsy showed grade 1 changes in 5 (13.5%) patients, grade 2 changes in 13 (35.1%) patients, grade 3 changes in 9 (24.3%) patients, grade 4 changes in 7 (18.9%) patients, grade 5 changes in 2 (5.4%) patients, and grade 6 changes in 2.7% patients. Antinuclear antibody (ANA) assay and anti-ds DNA were positive in 78.4 and 81.1%, respec-tively. We conclude that mesangial proliferative glomerulonephritis (grade 2) was the most common pattern of lupus nephritis encountered in our study. Timely diagnosis and treatment may improve the overall patients′ survival. Medicine R Sanjib Kumar Sharma verfasserin aut Narendra Bhatta verfasserin aut Sabina Bhattarai verfasserin aut Smriti Karki verfasserin aut Shailendra Shrestha verfasserin aut Suman Rijal verfasserin aut Prahlad Karkil verfasserin aut In Saudi Journal of Kidney Diseases and Transplantation Wolters Kluwer Medknow Publications, 2007 22(2011), 2, Seite 377-380 (DE-627)613740475 (DE-600)2526321-3 23203838 nnns volume:22 year:2011 number:2 pages:377-380 https://doaj.org/article/de5f31a0cd2148a0966bded0605ce61e kostenfrei http://www.sjkdt.org/article.asp?issn=1319-2442;year=2011;volume=22;issue=2;spage=377;epage=380;aulast=Dhakal kostenfrei https://doaj.org/toc/1319-2442 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 22 2011 2 377-380
allfieldsSound	(DE-627)DOAJ027981983 (DE-599)DOAJde5f31a0cd2148a0966bded0605ce61e DE-627 ger DE-627 rakwb eng Subodh Sagar Dhakal verfasserin aut Clinical features and histological patterns of lupus nephritis in Eastern Nepal 2011 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier To determine the clinical profile and patterns of lupus nephritis patients in Eastern Nepal, we studied 38 patients fulfilling the 1982 revised criteria of American College of Rheu-matology for systemic lupus erythematous (SLE), followed up from January 2004 to January 2008. Arthritis was a common initial feature in addition to variable cutaneous, cardiac, pulmonary and neuropsychiatric manifestations. Renal biopsy showed grade 1 changes in 5 (13.5%) patients, grade 2 changes in 13 (35.1%) patients, grade 3 changes in 9 (24.3%) patients, grade 4 changes in 7 (18.9%) patients, grade 5 changes in 2 (5.4%) patients, and grade 6 changes in 2.7% patients. Antinuclear antibody (ANA) assay and anti-ds DNA were positive in 78.4 and 81.1%, respec-tively. We conclude that mesangial proliferative glomerulonephritis (grade 2) was the most common pattern of lupus nephritis encountered in our study. Timely diagnosis and treatment may improve the overall patients′ survival. Medicine R Sanjib Kumar Sharma verfasserin aut Narendra Bhatta verfasserin aut Sabina Bhattarai verfasserin aut Smriti Karki verfasserin aut Shailendra Shrestha verfasserin aut Suman Rijal verfasserin aut Prahlad Karkil verfasserin aut In Saudi Journal of Kidney Diseases and Transplantation Wolters Kluwer Medknow Publications, 2007 22(2011), 2, Seite 377-380 (DE-627)613740475 (DE-600)2526321-3 23203838 nnns volume:22 year:2011 number:2 pages:377-380 https://doaj.org/article/de5f31a0cd2148a0966bded0605ce61e kostenfrei http://www.sjkdt.org/article.asp?issn=1319-2442;year=2011;volume=22;issue=2;spage=377;epage=380;aulast=Dhakal kostenfrei https://doaj.org/toc/1319-2442 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4246 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 22 2011 2 377-380
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author	Subodh Sagar Dhakal
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title	Clinical features and histological patterns of lupus nephritis in Eastern Nepal
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title_full	Clinical features and histological patterns of lupus nephritis in Eastern Nepal
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title_sort	clinical features and histological patterns of lupus nephritis in eastern nepal
title_auth	Clinical features and histological patterns of lupus nephritis in Eastern Nepal
abstract	To determine the clinical profile and patterns of lupus nephritis patients in Eastern Nepal, we studied 38 patients fulfilling the 1982 revised criteria of American College of Rheu-matology for systemic lupus erythematous (SLE), followed up from January 2004 to January 2008. Arthritis was a common initial feature in addition to variable cutaneous, cardiac, pulmonary and neuropsychiatric manifestations. Renal biopsy showed grade 1 changes in 5 (13.5%) patients, grade 2 changes in 13 (35.1%) patients, grade 3 changes in 9 (24.3%) patients, grade 4 changes in 7 (18.9%) patients, grade 5 changes in 2 (5.4%) patients, and grade 6 changes in 2.7% patients. Antinuclear antibody (ANA) assay and anti-ds DNA were positive in 78.4 and 81.1%, respec-tively. We conclude that mesangial proliferative glomerulonephritis (grade 2) was the most common pattern of lupus nephritis encountered in our study. Timely diagnosis and treatment may improve the overall patients′ survival.
abstractGer	To determine the clinical profile and patterns of lupus nephritis patients in Eastern Nepal, we studied 38 patients fulfilling the 1982 revised criteria of American College of Rheu-matology for systemic lupus erythematous (SLE), followed up from January 2004 to January 2008. Arthritis was a common initial feature in addition to variable cutaneous, cardiac, pulmonary and neuropsychiatric manifestations. Renal biopsy showed grade 1 changes in 5 (13.5%) patients, grade 2 changes in 13 (35.1%) patients, grade 3 changes in 9 (24.3%) patients, grade 4 changes in 7 (18.9%) patients, grade 5 changes in 2 (5.4%) patients, and grade 6 changes in 2.7% patients. Antinuclear antibody (ANA) assay and anti-ds DNA were positive in 78.4 and 81.1%, respec-tively. We conclude that mesangial proliferative glomerulonephritis (grade 2) was the most common pattern of lupus nephritis encountered in our study. Timely diagnosis and treatment may improve the overall patients′ survival.
abstract_unstemmed	To determine the clinical profile and patterns of lupus nephritis patients in Eastern Nepal, we studied 38 patients fulfilling the 1982 revised criteria of American College of Rheu-matology for systemic lupus erythematous (SLE), followed up from January 2004 to January 2008. Arthritis was a common initial feature in addition to variable cutaneous, cardiac, pulmonary and neuropsychiatric manifestations. Renal biopsy showed grade 1 changes in 5 (13.5%) patients, grade 2 changes in 13 (35.1%) patients, grade 3 changes in 9 (24.3%) patients, grade 4 changes in 7 (18.9%) patients, grade 5 changes in 2 (5.4%) patients, and grade 6 changes in 2.7% patients. Antinuclear antibody (ANA) assay and anti-ds DNA were positive in 78.4 and 81.1%, respec-tively. We conclude that mesangial proliferative glomerulonephritis (grade 2) was the most common pattern of lupus nephritis encountered in our study. Timely diagnosis and treatment may improve the overall patients′ survival.
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title_short	Clinical features and histological patterns of lupus nephritis in Eastern Nepal
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