Seroprevalence of Rubella Immunity (IgG Antibody) among Female Health Care Workers in a Hospital in Southern India
Introduction: Rubella is a mild exanthematous illness caused by Rubella virus which belongs to the family Togaviridae. Rubella is considered of public health importance for the teratogenic potential of the virus, this lead to disastrous consequences in pregnant women if contracted during first trime...
Ausführliche Beschreibung
Autor*in: |
S Kandasamy [verfasserIn] D Jeyakumari [verfasserIn] E Premalatha [verfasserIn] Jamunrani Srirangaramasamy [verfasserIn] M Balamurugan [verfasserIn] |
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E-Artikel |
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Sprache: |
Englisch |
Erschienen: |
2019 |
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Übergeordnetes Werk: |
In: Journal of Clinical and Diagnostic Research - JCDR Research and Publications Private Limited, 2009, 13(2019), 7, Seite DC10-DC13 |
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Übergeordnetes Werk: |
volume:13 ; year:2019 ; number:7 ; pages:DC10-DC13 |
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Link aufrufen |
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DOI / URN: |
10.7860/JCDR/2019/40961.12996 |
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Katalog-ID: |
DOAJ028213904 |
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520 | |a Introduction: Rubella is a mild exanthematous illness caused by Rubella virus which belongs to the family Togaviridae. Rubella is considered of public health importance for the teratogenic potential of the virus, this lead to disastrous consequences in pregnant women if contracted during first trimester. An effective and safe vaccine against rubella is available, yet according to estimation, over 100,000 infants are born with Congenital Rubella Syndrome (CRS) annually worldwide. Rubella is endemic in India and CRS contributes in morbidity and mortality among the live birth. As rubella vaccine has been incorporated in their immunisation schedule, the incidence of rubella has been reduced drastically. But still seronegative population has been noted in various studies in India. Aim: To evaluate the immune status (Rubella specific IgG antibody) of Rubella among Health Care Workers (HCW) of our hospital. Materials and Methods: A prospective, cross-sectional study was conducted among female health care students and workers (n=145) in a tertiary care teaching hospital in South Chennai from January to February 2017. Blood samples were collected after getting informed consent and serum was separated. A rubella specific IgG antibody was detected by ELISA using the commercially available kit as per the manufacturer’s instruction. Samples showing IgG antibody titre <10 IU/mL were taken as positive and ≤10 IU/mL as negative. The results were analysed statistically using Epi Info version 7.2. Results: A total n=145 samples were analysed and among which 124 (85.5%) workers had adequate titre and 21 (14.48%) were negative for rubella IgG antibody. The mean age of the participants was 19.65. The participants were MBBS students (n=75), BDS students (n=48), Laboratory technicians (n=12), Staff nurses (n=9) and Doctor (n=1). None of them was remembering their vaccination status. Conclusion: The study concludes that immunisation of HCWs against rubella is an important target regardless of their vaccination status. There is a more chance of exposure to infection and also in transmission of infection in the hospital environment. Hence, maintenance of immunity is an essential part of prevention and infection control scheme. | ||
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10.7860/JCDR/2019/40961.12996 doi (DE-627)DOAJ028213904 (DE-599)DOAJd6ff4f754104493184dc2dbd6008a064 DE-627 ger DE-627 rakwb eng S Kandasamy verfasserin aut Seroprevalence of Rubella Immunity (IgG Antibody) among Female Health Care Workers in a Hospital in Southern India 2019 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Introduction: Rubella is a mild exanthematous illness caused by Rubella virus which belongs to the family Togaviridae. Rubella is considered of public health importance for the teratogenic potential of the virus, this lead to disastrous consequences in pregnant women if contracted during first trimester. An effective and safe vaccine against rubella is available, yet according to estimation, over 100,000 infants are born with Congenital Rubella Syndrome (CRS) annually worldwide. Rubella is endemic in India and CRS contributes in morbidity and mortality among the live birth. As rubella vaccine has been incorporated in their immunisation schedule, the incidence of rubella has been reduced drastically. But still seronegative population has been noted in various studies in India. Aim: To evaluate the immune status (Rubella specific IgG antibody) of Rubella among Health Care Workers (HCW) of our hospital. Materials and Methods: A prospective, cross-sectional study was conducted among female health care students and workers (n=145) in a tertiary care teaching hospital in South Chennai from January to February 2017. Blood samples were collected after getting informed consent and serum was separated. A rubella specific IgG antibody was detected by ELISA using the commercially available kit as per the manufacturer’s instruction. Samples showing IgG antibody titre <10 IU/mL were taken as positive and ≤10 IU/mL as negative. The results were analysed statistically using Epi Info version 7.2. Results: A total n=145 samples were analysed and among which 124 (85.5%) workers had adequate titre and 21 (14.48%) were negative for rubella IgG antibody. The mean age of the participants was 19.65. The participants were MBBS students (n=75), BDS students (n=48), Laboratory technicians (n=12), Staff nurses (n=9) and Doctor (n=1). None of them was remembering their vaccination status. Conclusion: The study concludes that immunisation of HCWs against rubella is an important target regardless of their vaccination status. There is a more chance of exposure to infection and also in transmission of infection in the hospital environment. Hence, maintenance of immunity is an essential part of prevention and infection control scheme. immunisation medical students serosurvey Medicine R D Jeyakumari verfasserin aut E Premalatha verfasserin aut Jamunrani Srirangaramasamy verfasserin aut M Balamurugan verfasserin aut In Journal of Clinical and Diagnostic Research JCDR Research and Publications Private Limited, 2009 13(2019), 7, Seite DC10-DC13 (DE-627)789478048 (DE-600)2775283-5 0973709X nnns volume:13 year:2019 number:7 pages:DC10-DC13 https://doi.org/10.7860/JCDR/2019/40961.12996 kostenfrei https://doaj.org/article/d6ff4f754104493184dc2dbd6008a064 kostenfrei https://jcdr.net/articles/PDF/12996/40961_CE[Ra1]_F(SL)_PF1(AG_SHU)_PN(SL).pdf kostenfrei https://doaj.org/toc/2249-782X Journal toc kostenfrei https://doaj.org/toc/0973-709X Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 13 2019 7 DC10-DC13 |
spelling |
10.7860/JCDR/2019/40961.12996 doi (DE-627)DOAJ028213904 (DE-599)DOAJd6ff4f754104493184dc2dbd6008a064 DE-627 ger DE-627 rakwb eng S Kandasamy verfasserin aut Seroprevalence of Rubella Immunity (IgG Antibody) among Female Health Care Workers in a Hospital in Southern India 2019 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Introduction: Rubella is a mild exanthematous illness caused by Rubella virus which belongs to the family Togaviridae. Rubella is considered of public health importance for the teratogenic potential of the virus, this lead to disastrous consequences in pregnant women if contracted during first trimester. An effective and safe vaccine against rubella is available, yet according to estimation, over 100,000 infants are born with Congenital Rubella Syndrome (CRS) annually worldwide. Rubella is endemic in India and CRS contributes in morbidity and mortality among the live birth. As rubella vaccine has been incorporated in their immunisation schedule, the incidence of rubella has been reduced drastically. But still seronegative population has been noted in various studies in India. Aim: To evaluate the immune status (Rubella specific IgG antibody) of Rubella among Health Care Workers (HCW) of our hospital. Materials and Methods: A prospective, cross-sectional study was conducted among female health care students and workers (n=145) in a tertiary care teaching hospital in South Chennai from January to February 2017. Blood samples were collected after getting informed consent and serum was separated. A rubella specific IgG antibody was detected by ELISA using the commercially available kit as per the manufacturer’s instruction. Samples showing IgG antibody titre <10 IU/mL were taken as positive and ≤10 IU/mL as negative. The results were analysed statistically using Epi Info version 7.2. Results: A total n=145 samples were analysed and among which 124 (85.5%) workers had adequate titre and 21 (14.48%) were negative for rubella IgG antibody. The mean age of the participants was 19.65. The participants were MBBS students (n=75), BDS students (n=48), Laboratory technicians (n=12), Staff nurses (n=9) and Doctor (n=1). None of them was remembering their vaccination status. Conclusion: The study concludes that immunisation of HCWs against rubella is an important target regardless of their vaccination status. There is a more chance of exposure to infection and also in transmission of infection in the hospital environment. Hence, maintenance of immunity is an essential part of prevention and infection control scheme. immunisation medical students serosurvey Medicine R D Jeyakumari verfasserin aut E Premalatha verfasserin aut Jamunrani Srirangaramasamy verfasserin aut M Balamurugan verfasserin aut In Journal of Clinical and Diagnostic Research JCDR Research and Publications Private Limited, 2009 13(2019), 7, Seite DC10-DC13 (DE-627)789478048 (DE-600)2775283-5 0973709X nnns volume:13 year:2019 number:7 pages:DC10-DC13 https://doi.org/10.7860/JCDR/2019/40961.12996 kostenfrei https://doaj.org/article/d6ff4f754104493184dc2dbd6008a064 kostenfrei https://jcdr.net/articles/PDF/12996/40961_CE[Ra1]_F(SL)_PF1(AG_SHU)_PN(SL).pdf kostenfrei https://doaj.org/toc/2249-782X Journal toc kostenfrei https://doaj.org/toc/0973-709X Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 13 2019 7 DC10-DC13 |
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10.7860/JCDR/2019/40961.12996 doi (DE-627)DOAJ028213904 (DE-599)DOAJd6ff4f754104493184dc2dbd6008a064 DE-627 ger DE-627 rakwb eng S Kandasamy verfasserin aut Seroprevalence of Rubella Immunity (IgG Antibody) among Female Health Care Workers in a Hospital in Southern India 2019 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Introduction: Rubella is a mild exanthematous illness caused by Rubella virus which belongs to the family Togaviridae. Rubella is considered of public health importance for the teratogenic potential of the virus, this lead to disastrous consequences in pregnant women if contracted during first trimester. An effective and safe vaccine against rubella is available, yet according to estimation, over 100,000 infants are born with Congenital Rubella Syndrome (CRS) annually worldwide. Rubella is endemic in India and CRS contributes in morbidity and mortality among the live birth. As rubella vaccine has been incorporated in their immunisation schedule, the incidence of rubella has been reduced drastically. But still seronegative population has been noted in various studies in India. Aim: To evaluate the immune status (Rubella specific IgG antibody) of Rubella among Health Care Workers (HCW) of our hospital. Materials and Methods: A prospective, cross-sectional study was conducted among female health care students and workers (n=145) in a tertiary care teaching hospital in South Chennai from January to February 2017. Blood samples were collected after getting informed consent and serum was separated. A rubella specific IgG antibody was detected by ELISA using the commercially available kit as per the manufacturer’s instruction. Samples showing IgG antibody titre <10 IU/mL were taken as positive and ≤10 IU/mL as negative. The results were analysed statistically using Epi Info version 7.2. Results: A total n=145 samples were analysed and among which 124 (85.5%) workers had adequate titre and 21 (14.48%) were negative for rubella IgG antibody. The mean age of the participants was 19.65. The participants were MBBS students (n=75), BDS students (n=48), Laboratory technicians (n=12), Staff nurses (n=9) and Doctor (n=1). None of them was remembering their vaccination status. Conclusion: The study concludes that immunisation of HCWs against rubella is an important target regardless of their vaccination status. There is a more chance of exposure to infection and also in transmission of infection in the hospital environment. Hence, maintenance of immunity is an essential part of prevention and infection control scheme. immunisation medical students serosurvey Medicine R D Jeyakumari verfasserin aut E Premalatha verfasserin aut Jamunrani Srirangaramasamy verfasserin aut M Balamurugan verfasserin aut In Journal of Clinical and Diagnostic Research JCDR Research and Publications Private Limited, 2009 13(2019), 7, Seite DC10-DC13 (DE-627)789478048 (DE-600)2775283-5 0973709X nnns volume:13 year:2019 number:7 pages:DC10-DC13 https://doi.org/10.7860/JCDR/2019/40961.12996 kostenfrei https://doaj.org/article/d6ff4f754104493184dc2dbd6008a064 kostenfrei https://jcdr.net/articles/PDF/12996/40961_CE[Ra1]_F(SL)_PF1(AG_SHU)_PN(SL).pdf kostenfrei https://doaj.org/toc/2249-782X Journal toc kostenfrei https://doaj.org/toc/0973-709X Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 13 2019 7 DC10-DC13 |
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10.7860/JCDR/2019/40961.12996 doi (DE-627)DOAJ028213904 (DE-599)DOAJd6ff4f754104493184dc2dbd6008a064 DE-627 ger DE-627 rakwb eng S Kandasamy verfasserin aut Seroprevalence of Rubella Immunity (IgG Antibody) among Female Health Care Workers in a Hospital in Southern India 2019 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Introduction: Rubella is a mild exanthematous illness caused by Rubella virus which belongs to the family Togaviridae. Rubella is considered of public health importance for the teratogenic potential of the virus, this lead to disastrous consequences in pregnant women if contracted during first trimester. An effective and safe vaccine against rubella is available, yet according to estimation, over 100,000 infants are born with Congenital Rubella Syndrome (CRS) annually worldwide. Rubella is endemic in India and CRS contributes in morbidity and mortality among the live birth. As rubella vaccine has been incorporated in their immunisation schedule, the incidence of rubella has been reduced drastically. But still seronegative population has been noted in various studies in India. Aim: To evaluate the immune status (Rubella specific IgG antibody) of Rubella among Health Care Workers (HCW) of our hospital. Materials and Methods: A prospective, cross-sectional study was conducted among female health care students and workers (n=145) in a tertiary care teaching hospital in South Chennai from January to February 2017. Blood samples were collected after getting informed consent and serum was separated. A rubella specific IgG antibody was detected by ELISA using the commercially available kit as per the manufacturer’s instruction. Samples showing IgG antibody titre <10 IU/mL were taken as positive and ≤10 IU/mL as negative. The results were analysed statistically using Epi Info version 7.2. Results: A total n=145 samples were analysed and among which 124 (85.5%) workers had adequate titre and 21 (14.48%) were negative for rubella IgG antibody. The mean age of the participants was 19.65. The participants were MBBS students (n=75), BDS students (n=48), Laboratory technicians (n=12), Staff nurses (n=9) and Doctor (n=1). None of them was remembering their vaccination status. Conclusion: The study concludes that immunisation of HCWs against rubella is an important target regardless of their vaccination status. There is a more chance of exposure to infection and also in transmission of infection in the hospital environment. Hence, maintenance of immunity is an essential part of prevention and infection control scheme. immunisation medical students serosurvey Medicine R D Jeyakumari verfasserin aut E Premalatha verfasserin aut Jamunrani Srirangaramasamy verfasserin aut M Balamurugan verfasserin aut In Journal of Clinical and Diagnostic Research JCDR Research and Publications Private Limited, 2009 13(2019), 7, Seite DC10-DC13 (DE-627)789478048 (DE-600)2775283-5 0973709X nnns volume:13 year:2019 number:7 pages:DC10-DC13 https://doi.org/10.7860/JCDR/2019/40961.12996 kostenfrei https://doaj.org/article/d6ff4f754104493184dc2dbd6008a064 kostenfrei https://jcdr.net/articles/PDF/12996/40961_CE[Ra1]_F(SL)_PF1(AG_SHU)_PN(SL).pdf kostenfrei https://doaj.org/toc/2249-782X Journal toc kostenfrei https://doaj.org/toc/0973-709X Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2005 GBV_ILN_2009 GBV_ILN_2011 GBV_ILN_2014 GBV_ILN_2055 GBV_ILN_2111 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 13 2019 7 DC10-DC13 |
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Seroprevalence of Rubella Immunity (IgG Antibody) among Female Health Care Workers in a Hospital in Southern India |
abstract |
Introduction: Rubella is a mild exanthematous illness caused by Rubella virus which belongs to the family Togaviridae. Rubella is considered of public health importance for the teratogenic potential of the virus, this lead to disastrous consequences in pregnant women if contracted during first trimester. An effective and safe vaccine against rubella is available, yet according to estimation, over 100,000 infants are born with Congenital Rubella Syndrome (CRS) annually worldwide. Rubella is endemic in India and CRS contributes in morbidity and mortality among the live birth. As rubella vaccine has been incorporated in their immunisation schedule, the incidence of rubella has been reduced drastically. But still seronegative population has been noted in various studies in India. Aim: To evaluate the immune status (Rubella specific IgG antibody) of Rubella among Health Care Workers (HCW) of our hospital. Materials and Methods: A prospective, cross-sectional study was conducted among female health care students and workers (n=145) in a tertiary care teaching hospital in South Chennai from January to February 2017. Blood samples were collected after getting informed consent and serum was separated. A rubella specific IgG antibody was detected by ELISA using the commercially available kit as per the manufacturer’s instruction. Samples showing IgG antibody titre <10 IU/mL were taken as positive and ≤10 IU/mL as negative. The results were analysed statistically using Epi Info version 7.2. Results: A total n=145 samples were analysed and among which 124 (85.5%) workers had adequate titre and 21 (14.48%) were negative for rubella IgG antibody. The mean age of the participants was 19.65. The participants were MBBS students (n=75), BDS students (n=48), Laboratory technicians (n=12), Staff nurses (n=9) and Doctor (n=1). None of them was remembering their vaccination status. Conclusion: The study concludes that immunisation of HCWs against rubella is an important target regardless of their vaccination status. There is a more chance of exposure to infection and also in transmission of infection in the hospital environment. Hence, maintenance of immunity is an essential part of prevention and infection control scheme. |
abstractGer |
Introduction: Rubella is a mild exanthematous illness caused by Rubella virus which belongs to the family Togaviridae. Rubella is considered of public health importance for the teratogenic potential of the virus, this lead to disastrous consequences in pregnant women if contracted during first trimester. An effective and safe vaccine against rubella is available, yet according to estimation, over 100,000 infants are born with Congenital Rubella Syndrome (CRS) annually worldwide. Rubella is endemic in India and CRS contributes in morbidity and mortality among the live birth. As rubella vaccine has been incorporated in their immunisation schedule, the incidence of rubella has been reduced drastically. But still seronegative population has been noted in various studies in India. Aim: To evaluate the immune status (Rubella specific IgG antibody) of Rubella among Health Care Workers (HCW) of our hospital. Materials and Methods: A prospective, cross-sectional study was conducted among female health care students and workers (n=145) in a tertiary care teaching hospital in South Chennai from January to February 2017. Blood samples were collected after getting informed consent and serum was separated. A rubella specific IgG antibody was detected by ELISA using the commercially available kit as per the manufacturer’s instruction. Samples showing IgG antibody titre <10 IU/mL were taken as positive and ≤10 IU/mL as negative. The results were analysed statistically using Epi Info version 7.2. Results: A total n=145 samples were analysed and among which 124 (85.5%) workers had adequate titre and 21 (14.48%) were negative for rubella IgG antibody. The mean age of the participants was 19.65. The participants were MBBS students (n=75), BDS students (n=48), Laboratory technicians (n=12), Staff nurses (n=9) and Doctor (n=1). None of them was remembering their vaccination status. Conclusion: The study concludes that immunisation of HCWs against rubella is an important target regardless of their vaccination status. There is a more chance of exposure to infection and also in transmission of infection in the hospital environment. Hence, maintenance of immunity is an essential part of prevention and infection control scheme. |
abstract_unstemmed |
Introduction: Rubella is a mild exanthematous illness caused by Rubella virus which belongs to the family Togaviridae. Rubella is considered of public health importance for the teratogenic potential of the virus, this lead to disastrous consequences in pregnant women if contracted during first trimester. An effective and safe vaccine against rubella is available, yet according to estimation, over 100,000 infants are born with Congenital Rubella Syndrome (CRS) annually worldwide. Rubella is endemic in India and CRS contributes in morbidity and mortality among the live birth. As rubella vaccine has been incorporated in their immunisation schedule, the incidence of rubella has been reduced drastically. But still seronegative population has been noted in various studies in India. Aim: To evaluate the immune status (Rubella specific IgG antibody) of Rubella among Health Care Workers (HCW) of our hospital. Materials and Methods: A prospective, cross-sectional study was conducted among female health care students and workers (n=145) in a tertiary care teaching hospital in South Chennai from January to February 2017. Blood samples were collected after getting informed consent and serum was separated. A rubella specific IgG antibody was detected by ELISA using the commercially available kit as per the manufacturer’s instruction. Samples showing IgG antibody titre <10 IU/mL were taken as positive and ≤10 IU/mL as negative. The results were analysed statistically using Epi Info version 7.2. Results: A total n=145 samples were analysed and among which 124 (85.5%) workers had adequate titre and 21 (14.48%) were negative for rubella IgG antibody. The mean age of the participants was 19.65. The participants were MBBS students (n=75), BDS students (n=48), Laboratory technicians (n=12), Staff nurses (n=9) and Doctor (n=1). None of them was remembering their vaccination status. Conclusion: The study concludes that immunisation of HCWs against rubella is an important target regardless of their vaccination status. There is a more chance of exposure to infection and also in transmission of infection in the hospital environment. Hence, maintenance of immunity is an essential part of prevention and infection control scheme. |
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title_short |
Seroprevalence of Rubella Immunity (IgG Antibody) among Female Health Care Workers in a Hospital in Southern India |
url |
https://doi.org/10.7860/JCDR/2019/40961.12996 https://doaj.org/article/d6ff4f754104493184dc2dbd6008a064 https://jcdr.net/articles/PDF/12996/40961_CE[Ra1]_F(SL)_PF1(AG_SHU)_PN(SL).pdf https://doaj.org/toc/2249-782X https://doaj.org/toc/0973-709X |
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D Jeyakumari E Premalatha Jamunrani Srirangaramasamy M Balamurugan |
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D Jeyakumari E Premalatha Jamunrani Srirangaramasamy M Balamurugan |
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up_date |
2024-07-03T16:21:50.783Z |
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