Price and Prejudice? The Value of Chimeric Antigen Receptor (CAR) T-Cell Therapy

Although chimeric antigen receptor (CAR) T-cell therapy has shown a high response rate in lymphoma patients, its cost-effectiveness is controversial due to the high price and uncertainty of the clinical evidence. In addition to the high acquisition cost of CAR T-cell therapy, procedure and facility...
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Gespeichert in:

Autor*in:	Gyeyoung Choi [verfasserIn] Gyeongseon Shin [verfasserIn] SeungJin Bae [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2022

Schlagwörter:	chimeric antigen receptor T-cell therapy CAR T-cell economic evaluation value

Übergeordnetes Werk:	In: International Journal of Environmental Research and Public Health - MDPI AG, 2005, 19(2022), 12366, p 12366
Übergeordnetes Werk:	volume:19 ; year:2022 ; number:12366, p 12366

Links:	Link aufrufen Link aufrufen Link aufrufen Journal toc Journal toc

DOI / URN:	10.3390/ijerph191912366

Katalog-ID:	DOAJ028312058

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language	English
source	In International Journal of Environmental Research and Public Health 19(2022), 12366, p 12366 volume:19 year:2022 number:12366, p 12366
sourceStr	In International Journal of Environmental Research and Public Health 19(2022), 12366, p 12366 volume:19 year:2022 number:12366, p 12366
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author	Gyeyoung Choi
spellingShingle	Gyeyoung Choi misc chimeric antigen receptor T-cell therapy misc CAR T-cell misc economic evaluation misc value misc Medicine misc R Price and Prejudice? The Value of Chimeric Antigen Receptor (CAR) T-Cell Therapy
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topic	misc chimeric antigen receptor T-cell therapy misc CAR T-cell misc economic evaluation misc value misc Medicine misc R
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title	Price and Prejudice? The Value of Chimeric Antigen Receptor (CAR) T-Cell Therapy
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title_sort	price and prejudice? the value of chimeric antigen receptor (car) t-cell therapy
title_auth	Price and Prejudice? The Value of Chimeric Antigen Receptor (CAR) T-Cell Therapy
abstract	Although chimeric antigen receptor (CAR) T-cell therapy has shown a high response rate in lymphoma patients, its cost-effectiveness is controversial due to the high price and uncertainty of the clinical evidence. In addition to the high acquisition cost of CAR T-cell therapy, procedure and facility cost increase the financial burden considering the frequency of adverse events such as cytokine release syndrome. In clinical research, relatively short follow-up periods were used compared to traditional cancer agents. In addition, head-to-head comparative effectiveness data are unavailable, which is an important factor when evaluating the cost-effectiveness of a new treatment. Additional evidence that will compensate for the uncertainty of existing clinical data is needed for full evaluation of long-term efficacy, safety, and comparative effectiveness.
abstractGer	Although chimeric antigen receptor (CAR) T-cell therapy has shown a high response rate in lymphoma patients, its cost-effectiveness is controversial due to the high price and uncertainty of the clinical evidence. In addition to the high acquisition cost of CAR T-cell therapy, procedure and facility cost increase the financial burden considering the frequency of adverse events such as cytokine release syndrome. In clinical research, relatively short follow-up periods were used compared to traditional cancer agents. In addition, head-to-head comparative effectiveness data are unavailable, which is an important factor when evaluating the cost-effectiveness of a new treatment. Additional evidence that will compensate for the uncertainty of existing clinical data is needed for full evaluation of long-term efficacy, safety, and comparative effectiveness.
abstract_unstemmed	Although chimeric antigen receptor (CAR) T-cell therapy has shown a high response rate in lymphoma patients, its cost-effectiveness is controversial due to the high price and uncertainty of the clinical evidence. In addition to the high acquisition cost of CAR T-cell therapy, procedure and facility cost increase the financial burden considering the frequency of adverse events such as cytokine release syndrome. In clinical research, relatively short follow-up periods were used compared to traditional cancer agents. In addition, head-to-head comparative effectiveness data are unavailable, which is an important factor when evaluating the cost-effectiveness of a new treatment. Additional evidence that will compensate for the uncertainty of existing clinical data is needed for full evaluation of long-term efficacy, safety, and comparative effectiveness.
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title_short	Price and Prejudice? The Value of Chimeric Antigen Receptor (CAR) T-Cell Therapy
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