Subjective Sleep Disruption and Mood Disorders are Associated with the Risk of Chronic Pain in Patients with Obstructive Sleep Apnea
Liu Liu1 *, Xiao Li2,3 *, Pei Xue,4 Min Wu,4 Si Zeng,1 Yuee Dai,1 Junying Zhou4,5 1Department of Anesthesiology, Sichuan Provincial People’s Hospital, University of Electronic Science and Technology of China, Chengdu, People’s Republic of China; 2Department of Psychology, Sleep Resea...
Ausführliche Beschreibung
Autor*in: |
Liu L [verfasserIn] Li X [verfasserIn] Xue P [verfasserIn] Wu M [verfasserIn] Zeng S [verfasserIn] Dai Y [verfasserIn] Zhou J [verfasserIn] |
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2022 |
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In: Nature and Science of Sleep - Dove Medical Press, 2010, (2022), Seite 2023-2032 |
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year:2022 ; pages:2023-2032 |
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DOAJ029010705 |
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(DE-627)DOAJ029010705 (DE-599)DOAJ90edbc5f88cd4152a8acfdcdc26e9456 DE-627 ger DE-627 rakwb eng RC435-571 QP351-495 Liu L verfasserin aut Subjective Sleep Disruption and Mood Disorders are Associated with the Risk of Chronic Pain in Patients with Obstructive Sleep Apnea 2022 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Liu Liu1 *, Xiao Li2,3 *, Pei Xue,4 Min Wu,4 Si Zeng,1 Yuee Dai,1 Junying Zhou4,5 1Department of Anesthesiology, Sichuan Provincial People’s Hospital, University of Electronic Science and Technology of China, Chengdu, People’s Republic of China; 2Department of Psychology, Sleep Research Clinic and Laboratory, the University of Hong Kong, Hong Kong Special Administrative Regions, People’s Republic of China; 3State Key Laboratory of Brain and Cognitive Sciences, the University of Hong Kong, Hong Kong Special Administrative Regions, People’s Republic of China; 4Sleep Medicine Center, West China Hospital, Sichuan University, Chengdu, People’s Republic of China; 5Department of Neurology, West China Hospital, Sichuan University, Chengdu, People’s Republic of China*These authors contributed equally to this workCorrespondence: Junying Zhou, Sleep Medicine Center, West China Hospital, Sichuan University, 28 Dian Xin Nan Jie, Chengdu, Sichuan Province, People’s Republic of China, Email zhoujy2016scu.edu.cnObjective: This study aimed to determine the prevalence of chronic pain and its risk factors in patients with obstructive sleep apnea (OSA).Methods: A total of 145 patients diagnosed with OSA were consecutively recruited from the Sleep Medicine Center in West China Hospital. All patients were divided into two groups including OSA with and without chronic pain. They were assessed the subjective sleep (Pittsburgh Sleep Quality Index, Insomnia Severity Index), objective sleep (polysomnography), mood symptoms (Hamilton Depression Rating Scale, Hamilton Anxiety Rating Scale), and pain characteristics (Short-Form McGill Pain Questionnaire). Demographic, clinical, subjective and objective sleep parameters were compared between OSA patients with and without chronic pain. Binary logistic regression models and linear regression models were used to examine the risk factors of chronic pain in OSA.Results: Fifty-five (37.9%) patients with OSA were diagnosed with chronic pain. There were more severe subjective sleep disruption and symptoms of anxiety and depression in patients with chronic pain compared to those without chronic pain. After controlling for potential confounders, poor subjective sleep quality and severe insomnia and mood disorders (all ps < 0.05), but not objective sleep fragmentation or nocturnal hypoxemia (all ps < 0.05) were associated with the increased risk of pain and pain intensity, respectively.Conclusion: More than one-third of patients with OSA had chronic pain. Subjective sleep disruption and mood disorders are the risk factors of chronic pain in OSA. Our findings suggest that subjective sleep quality should be valued highly in the relationship between OSA and pain.Keywords: obstructive sleep apnea, subjective sleep disruption, insomnia, anxiety, depression, chronic pain obstructive sleep apnea subjective sleep disruption insomnia anxiety depression chronic pain Psychiatry Neurophysiology and neuropsychology Li X verfasserin aut Xue P verfasserin aut Wu M verfasserin aut Zeng S verfasserin aut Dai Y verfasserin aut Zhou J verfasserin aut In Nature and Science of Sleep Dove Medical Press, 2010 (2022), Seite 2023-2032 (DE-627)642890161 (DE-600)2587468-8 11791608 nnns year:2022 pages:2023-2032 https://doaj.org/article/90edbc5f88cd4152a8acfdcdc26e9456 kostenfrei https://www.dovepress.com/subjective-sleep-disruption-and-mood-disorders-are-associated-with-the-peer-reviewed-fulltext-article-NSS kostenfrei https://doaj.org/toc/1179-1608 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 2022 2023-2032 |
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(DE-627)DOAJ029010705 (DE-599)DOAJ90edbc5f88cd4152a8acfdcdc26e9456 DE-627 ger DE-627 rakwb eng RC435-571 QP351-495 Liu L verfasserin aut Subjective Sleep Disruption and Mood Disorders are Associated with the Risk of Chronic Pain in Patients with Obstructive Sleep Apnea 2022 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Liu Liu1 *, Xiao Li2,3 *, Pei Xue,4 Min Wu,4 Si Zeng,1 Yuee Dai,1 Junying Zhou4,5 1Department of Anesthesiology, Sichuan Provincial People’s Hospital, University of Electronic Science and Technology of China, Chengdu, People’s Republic of China; 2Department of Psychology, Sleep Research Clinic and Laboratory, the University of Hong Kong, Hong Kong Special Administrative Regions, People’s Republic of China; 3State Key Laboratory of Brain and Cognitive Sciences, the University of Hong Kong, Hong Kong Special Administrative Regions, People’s Republic of China; 4Sleep Medicine Center, West China Hospital, Sichuan University, Chengdu, People’s Republic of China; 5Department of Neurology, West China Hospital, Sichuan University, Chengdu, People’s Republic of China*These authors contributed equally to this workCorrespondence: Junying Zhou, Sleep Medicine Center, West China Hospital, Sichuan University, 28 Dian Xin Nan Jie, Chengdu, Sichuan Province, People’s Republic of China, Email zhoujy2016scu.edu.cnObjective: This study aimed to determine the prevalence of chronic pain and its risk factors in patients with obstructive sleep apnea (OSA).Methods: A total of 145 patients diagnosed with OSA were consecutively recruited from the Sleep Medicine Center in West China Hospital. All patients were divided into two groups including OSA with and without chronic pain. They were assessed the subjective sleep (Pittsburgh Sleep Quality Index, Insomnia Severity Index), objective sleep (polysomnography), mood symptoms (Hamilton Depression Rating Scale, Hamilton Anxiety Rating Scale), and pain characteristics (Short-Form McGill Pain Questionnaire). Demographic, clinical, subjective and objective sleep parameters were compared between OSA patients with and without chronic pain. Binary logistic regression models and linear regression models were used to examine the risk factors of chronic pain in OSA.Results: Fifty-five (37.9%) patients with OSA were diagnosed with chronic pain. There were more severe subjective sleep disruption and symptoms of anxiety and depression in patients with chronic pain compared to those without chronic pain. After controlling for potential confounders, poor subjective sleep quality and severe insomnia and mood disorders (all ps < 0.05), but not objective sleep fragmentation or nocturnal hypoxemia (all ps < 0.05) were associated with the increased risk of pain and pain intensity, respectively.Conclusion: More than one-third of patients with OSA had chronic pain. Subjective sleep disruption and mood disorders are the risk factors of chronic pain in OSA. Our findings suggest that subjective sleep quality should be valued highly in the relationship between OSA and pain.Keywords: obstructive sleep apnea, subjective sleep disruption, insomnia, anxiety, depression, chronic pain obstructive sleep apnea subjective sleep disruption insomnia anxiety depression chronic pain Psychiatry Neurophysiology and neuropsychology Li X verfasserin aut Xue P verfasserin aut Wu M verfasserin aut Zeng S verfasserin aut Dai Y verfasserin aut Zhou J verfasserin aut In Nature and Science of Sleep Dove Medical Press, 2010 (2022), Seite 2023-2032 (DE-627)642890161 (DE-600)2587468-8 11791608 nnns year:2022 pages:2023-2032 https://doaj.org/article/90edbc5f88cd4152a8acfdcdc26e9456 kostenfrei https://www.dovepress.com/subjective-sleep-disruption-and-mood-disorders-are-associated-with-the-peer-reviewed-fulltext-article-NSS kostenfrei https://doaj.org/toc/1179-1608 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 2022 2023-2032 |
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(DE-627)DOAJ029010705 (DE-599)DOAJ90edbc5f88cd4152a8acfdcdc26e9456 DE-627 ger DE-627 rakwb eng RC435-571 QP351-495 Liu L verfasserin aut Subjective Sleep Disruption and Mood Disorders are Associated with the Risk of Chronic Pain in Patients with Obstructive Sleep Apnea 2022 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Liu Liu1 *, Xiao Li2,3 *, Pei Xue,4 Min Wu,4 Si Zeng,1 Yuee Dai,1 Junying Zhou4,5 1Department of Anesthesiology, Sichuan Provincial People’s Hospital, University of Electronic Science and Technology of China, Chengdu, People’s Republic of China; 2Department of Psychology, Sleep Research Clinic and Laboratory, the University of Hong Kong, Hong Kong Special Administrative Regions, People’s Republic of China; 3State Key Laboratory of Brain and Cognitive Sciences, the University of Hong Kong, Hong Kong Special Administrative Regions, People’s Republic of China; 4Sleep Medicine Center, West China Hospital, Sichuan University, Chengdu, People’s Republic of China; 5Department of Neurology, West China Hospital, Sichuan University, Chengdu, People’s Republic of China*These authors contributed equally to this workCorrespondence: Junying Zhou, Sleep Medicine Center, West China Hospital, Sichuan University, 28 Dian Xin Nan Jie, Chengdu, Sichuan Province, People’s Republic of China, Email zhoujy2016scu.edu.cnObjective: This study aimed to determine the prevalence of chronic pain and its risk factors in patients with obstructive sleep apnea (OSA).Methods: A total of 145 patients diagnosed with OSA were consecutively recruited from the Sleep Medicine Center in West China Hospital. All patients were divided into two groups including OSA with and without chronic pain. They were assessed the subjective sleep (Pittsburgh Sleep Quality Index, Insomnia Severity Index), objective sleep (polysomnography), mood symptoms (Hamilton Depression Rating Scale, Hamilton Anxiety Rating Scale), and pain characteristics (Short-Form McGill Pain Questionnaire). Demographic, clinical, subjective and objective sleep parameters were compared between OSA patients with and without chronic pain. Binary logistic regression models and linear regression models were used to examine the risk factors of chronic pain in OSA.Results: Fifty-five (37.9%) patients with OSA were diagnosed with chronic pain. There were more severe subjective sleep disruption and symptoms of anxiety and depression in patients with chronic pain compared to those without chronic pain. After controlling for potential confounders, poor subjective sleep quality and severe insomnia and mood disorders (all ps < 0.05), but not objective sleep fragmentation or nocturnal hypoxemia (all ps < 0.05) were associated with the increased risk of pain and pain intensity, respectively.Conclusion: More than one-third of patients with OSA had chronic pain. Subjective sleep disruption and mood disorders are the risk factors of chronic pain in OSA. Our findings suggest that subjective sleep quality should be valued highly in the relationship between OSA and pain.Keywords: obstructive sleep apnea, subjective sleep disruption, insomnia, anxiety, depression, chronic pain obstructive sleep apnea subjective sleep disruption insomnia anxiety depression chronic pain Psychiatry Neurophysiology and neuropsychology Li X verfasserin aut Xue P verfasserin aut Wu M verfasserin aut Zeng S verfasserin aut Dai Y verfasserin aut Zhou J verfasserin aut In Nature and Science of Sleep Dove Medical Press, 2010 (2022), Seite 2023-2032 (DE-627)642890161 (DE-600)2587468-8 11791608 nnns year:2022 pages:2023-2032 https://doaj.org/article/90edbc5f88cd4152a8acfdcdc26e9456 kostenfrei https://www.dovepress.com/subjective-sleep-disruption-and-mood-disorders-are-associated-with-the-peer-reviewed-fulltext-article-NSS kostenfrei https://doaj.org/toc/1179-1608 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 2022 2023-2032 |
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(DE-627)DOAJ029010705 (DE-599)DOAJ90edbc5f88cd4152a8acfdcdc26e9456 DE-627 ger DE-627 rakwb eng RC435-571 QP351-495 Liu L verfasserin aut Subjective Sleep Disruption and Mood Disorders are Associated with the Risk of Chronic Pain in Patients with Obstructive Sleep Apnea 2022 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Liu Liu1 *, Xiao Li2,3 *, Pei Xue,4 Min Wu,4 Si Zeng,1 Yuee Dai,1 Junying Zhou4,5 1Department of Anesthesiology, Sichuan Provincial People’s Hospital, University of Electronic Science and Technology of China, Chengdu, People’s Republic of China; 2Department of Psychology, Sleep Research Clinic and Laboratory, the University of Hong Kong, Hong Kong Special Administrative Regions, People’s Republic of China; 3State Key Laboratory of Brain and Cognitive Sciences, the University of Hong Kong, Hong Kong Special Administrative Regions, People’s Republic of China; 4Sleep Medicine Center, West China Hospital, Sichuan University, Chengdu, People’s Republic of China; 5Department of Neurology, West China Hospital, Sichuan University, Chengdu, People’s Republic of China*These authors contributed equally to this workCorrespondence: Junying Zhou, Sleep Medicine Center, West China Hospital, Sichuan University, 28 Dian Xin Nan Jie, Chengdu, Sichuan Province, People’s Republic of China, Email zhoujy2016scu.edu.cnObjective: This study aimed to determine the prevalence of chronic pain and its risk factors in patients with obstructive sleep apnea (OSA).Methods: A total of 145 patients diagnosed with OSA were consecutively recruited from the Sleep Medicine Center in West China Hospital. All patients were divided into two groups including OSA with and without chronic pain. They were assessed the subjective sleep (Pittsburgh Sleep Quality Index, Insomnia Severity Index), objective sleep (polysomnography), mood symptoms (Hamilton Depression Rating Scale, Hamilton Anxiety Rating Scale), and pain characteristics (Short-Form McGill Pain Questionnaire). Demographic, clinical, subjective and objective sleep parameters were compared between OSA patients with and without chronic pain. Binary logistic regression models and linear regression models were used to examine the risk factors of chronic pain in OSA.Results: Fifty-five (37.9%) patients with OSA were diagnosed with chronic pain. There were more severe subjective sleep disruption and symptoms of anxiety and depression in patients with chronic pain compared to those without chronic pain. After controlling for potential confounders, poor subjective sleep quality and severe insomnia and mood disorders (all ps < 0.05), but not objective sleep fragmentation or nocturnal hypoxemia (all ps < 0.05) were associated with the increased risk of pain and pain intensity, respectively.Conclusion: More than one-third of patients with OSA had chronic pain. Subjective sleep disruption and mood disorders are the risk factors of chronic pain in OSA. Our findings suggest that subjective sleep quality should be valued highly in the relationship between OSA and pain.Keywords: obstructive sleep apnea, subjective sleep disruption, insomnia, anxiety, depression, chronic pain obstructive sleep apnea subjective sleep disruption insomnia anxiety depression chronic pain Psychiatry Neurophysiology and neuropsychology Li X verfasserin aut Xue P verfasserin aut Wu M verfasserin aut Zeng S verfasserin aut Dai Y verfasserin aut Zhou J verfasserin aut In Nature and Science of Sleep Dove Medical Press, 2010 (2022), Seite 2023-2032 (DE-627)642890161 (DE-600)2587468-8 11791608 nnns year:2022 pages:2023-2032 https://doaj.org/article/90edbc5f88cd4152a8acfdcdc26e9456 kostenfrei https://www.dovepress.com/subjective-sleep-disruption-and-mood-disorders-are-associated-with-the-peer-reviewed-fulltext-article-NSS kostenfrei https://doaj.org/toc/1179-1608 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 2022 2023-2032 |
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(DE-627)DOAJ029010705 (DE-599)DOAJ90edbc5f88cd4152a8acfdcdc26e9456 DE-627 ger DE-627 rakwb eng RC435-571 QP351-495 Liu L verfasserin aut Subjective Sleep Disruption and Mood Disorders are Associated with the Risk of Chronic Pain in Patients with Obstructive Sleep Apnea 2022 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Liu Liu1 *, Xiao Li2,3 *, Pei Xue,4 Min Wu,4 Si Zeng,1 Yuee Dai,1 Junying Zhou4,5 1Department of Anesthesiology, Sichuan Provincial People’s Hospital, University of Electronic Science and Technology of China, Chengdu, People’s Republic of China; 2Department of Psychology, Sleep Research Clinic and Laboratory, the University of Hong Kong, Hong Kong Special Administrative Regions, People’s Republic of China; 3State Key Laboratory of Brain and Cognitive Sciences, the University of Hong Kong, Hong Kong Special Administrative Regions, People’s Republic of China; 4Sleep Medicine Center, West China Hospital, Sichuan University, Chengdu, People’s Republic of China; 5Department of Neurology, West China Hospital, Sichuan University, Chengdu, People’s Republic of China*These authors contributed equally to this workCorrespondence: Junying Zhou, Sleep Medicine Center, West China Hospital, Sichuan University, 28 Dian Xin Nan Jie, Chengdu, Sichuan Province, People’s Republic of China, Email zhoujy2016scu.edu.cnObjective: This study aimed to determine the prevalence of chronic pain and its risk factors in patients with obstructive sleep apnea (OSA).Methods: A total of 145 patients diagnosed with OSA were consecutively recruited from the Sleep Medicine Center in West China Hospital. All patients were divided into two groups including OSA with and without chronic pain. They were assessed the subjective sleep (Pittsburgh Sleep Quality Index, Insomnia Severity Index), objective sleep (polysomnography), mood symptoms (Hamilton Depression Rating Scale, Hamilton Anxiety Rating Scale), and pain characteristics (Short-Form McGill Pain Questionnaire). Demographic, clinical, subjective and objective sleep parameters were compared between OSA patients with and without chronic pain. Binary logistic regression models and linear regression models were used to examine the risk factors of chronic pain in OSA.Results: Fifty-five (37.9%) patients with OSA were diagnosed with chronic pain. There were more severe subjective sleep disruption and symptoms of anxiety and depression in patients with chronic pain compared to those without chronic pain. After controlling for potential confounders, poor subjective sleep quality and severe insomnia and mood disorders (all ps < 0.05), but not objective sleep fragmentation or nocturnal hypoxemia (all ps < 0.05) were associated with the increased risk of pain and pain intensity, respectively.Conclusion: More than one-third of patients with OSA had chronic pain. Subjective sleep disruption and mood disorders are the risk factors of chronic pain in OSA. Our findings suggest that subjective sleep quality should be valued highly in the relationship between OSA and pain.Keywords: obstructive sleep apnea, subjective sleep disruption, insomnia, anxiety, depression, chronic pain obstructive sleep apnea subjective sleep disruption insomnia anxiety depression chronic pain Psychiatry Neurophysiology and neuropsychology Li X verfasserin aut Xue P verfasserin aut Wu M verfasserin aut Zeng S verfasserin aut Dai Y verfasserin aut Zhou J verfasserin aut In Nature and Science of Sleep Dove Medical Press, 2010 (2022), Seite 2023-2032 (DE-627)642890161 (DE-600)2587468-8 11791608 nnns year:2022 pages:2023-2032 https://doaj.org/article/90edbc5f88cd4152a8acfdcdc26e9456 kostenfrei https://www.dovepress.com/subjective-sleep-disruption-and-mood-disorders-are-associated-with-the-peer-reviewed-fulltext-article-NSS kostenfrei https://doaj.org/toc/1179-1608 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_11 GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2003 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 2022 2023-2032 |
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Subjective Sleep Disruption and Mood Disorders are Associated with the Risk of Chronic Pain in Patients with Obstructive Sleep Apnea |
abstract |
Liu Liu1 *, Xiao Li2,3 *, Pei Xue,4 Min Wu,4 Si Zeng,1 Yuee Dai,1 Junying Zhou4,5 1Department of Anesthesiology, Sichuan Provincial People’s Hospital, University of Electronic Science and Technology of China, Chengdu, People’s Republic of China; 2Department of Psychology, Sleep Research Clinic and Laboratory, the University of Hong Kong, Hong Kong Special Administrative Regions, People’s Republic of China; 3State Key Laboratory of Brain and Cognitive Sciences, the University of Hong Kong, Hong Kong Special Administrative Regions, People’s Republic of China; 4Sleep Medicine Center, West China Hospital, Sichuan University, Chengdu, People’s Republic of China; 5Department of Neurology, West China Hospital, Sichuan University, Chengdu, People’s Republic of China*These authors contributed equally to this workCorrespondence: Junying Zhou, Sleep Medicine Center, West China Hospital, Sichuan University, 28 Dian Xin Nan Jie, Chengdu, Sichuan Province, People’s Republic of China, Email zhoujy2016scu.edu.cnObjective: This study aimed to determine the prevalence of chronic pain and its risk factors in patients with obstructive sleep apnea (OSA).Methods: A total of 145 patients diagnosed with OSA were consecutively recruited from the Sleep Medicine Center in West China Hospital. All patients were divided into two groups including OSA with and without chronic pain. They were assessed the subjective sleep (Pittsburgh Sleep Quality Index, Insomnia Severity Index), objective sleep (polysomnography), mood symptoms (Hamilton Depression Rating Scale, Hamilton Anxiety Rating Scale), and pain characteristics (Short-Form McGill Pain Questionnaire). Demographic, clinical, subjective and objective sleep parameters were compared between OSA patients with and without chronic pain. Binary logistic regression models and linear regression models were used to examine the risk factors of chronic pain in OSA.Results: Fifty-five (37.9%) patients with OSA were diagnosed with chronic pain. There were more severe subjective sleep disruption and symptoms of anxiety and depression in patients with chronic pain compared to those without chronic pain. After controlling for potential confounders, poor subjective sleep quality and severe insomnia and mood disorders (all ps < 0.05), but not objective sleep fragmentation or nocturnal hypoxemia (all ps < 0.05) were associated with the increased risk of pain and pain intensity, respectively.Conclusion: More than one-third of patients with OSA had chronic pain. Subjective sleep disruption and mood disorders are the risk factors of chronic pain in OSA. Our findings suggest that subjective sleep quality should be valued highly in the relationship between OSA and pain.Keywords: obstructive sleep apnea, subjective sleep disruption, insomnia, anxiety, depression, chronic pain |
abstractGer |
Liu Liu1 *, Xiao Li2,3 *, Pei Xue,4 Min Wu,4 Si Zeng,1 Yuee Dai,1 Junying Zhou4,5 1Department of Anesthesiology, Sichuan Provincial People’s Hospital, University of Electronic Science and Technology of China, Chengdu, People’s Republic of China; 2Department of Psychology, Sleep Research Clinic and Laboratory, the University of Hong Kong, Hong Kong Special Administrative Regions, People’s Republic of China; 3State Key Laboratory of Brain and Cognitive Sciences, the University of Hong Kong, Hong Kong Special Administrative Regions, People’s Republic of China; 4Sleep Medicine Center, West China Hospital, Sichuan University, Chengdu, People’s Republic of China; 5Department of Neurology, West China Hospital, Sichuan University, Chengdu, People’s Republic of China*These authors contributed equally to this workCorrespondence: Junying Zhou, Sleep Medicine Center, West China Hospital, Sichuan University, 28 Dian Xin Nan Jie, Chengdu, Sichuan Province, People’s Republic of China, Email zhoujy2016scu.edu.cnObjective: This study aimed to determine the prevalence of chronic pain and its risk factors in patients with obstructive sleep apnea (OSA).Methods: A total of 145 patients diagnosed with OSA were consecutively recruited from the Sleep Medicine Center in West China Hospital. All patients were divided into two groups including OSA with and without chronic pain. They were assessed the subjective sleep (Pittsburgh Sleep Quality Index, Insomnia Severity Index), objective sleep (polysomnography), mood symptoms (Hamilton Depression Rating Scale, Hamilton Anxiety Rating Scale), and pain characteristics (Short-Form McGill Pain Questionnaire). Demographic, clinical, subjective and objective sleep parameters were compared between OSA patients with and without chronic pain. Binary logistic regression models and linear regression models were used to examine the risk factors of chronic pain in OSA.Results: Fifty-five (37.9%) patients with OSA were diagnosed with chronic pain. There were more severe subjective sleep disruption and symptoms of anxiety and depression in patients with chronic pain compared to those without chronic pain. After controlling for potential confounders, poor subjective sleep quality and severe insomnia and mood disorders (all ps < 0.05), but not objective sleep fragmentation or nocturnal hypoxemia (all ps < 0.05) were associated with the increased risk of pain and pain intensity, respectively.Conclusion: More than one-third of patients with OSA had chronic pain. Subjective sleep disruption and mood disorders are the risk factors of chronic pain in OSA. Our findings suggest that subjective sleep quality should be valued highly in the relationship between OSA and pain.Keywords: obstructive sleep apnea, subjective sleep disruption, insomnia, anxiety, depression, chronic pain |
abstract_unstemmed |
Liu Liu1 *, Xiao Li2,3 *, Pei Xue,4 Min Wu,4 Si Zeng,1 Yuee Dai,1 Junying Zhou4,5 1Department of Anesthesiology, Sichuan Provincial People’s Hospital, University of Electronic Science and Technology of China, Chengdu, People’s Republic of China; 2Department of Psychology, Sleep Research Clinic and Laboratory, the University of Hong Kong, Hong Kong Special Administrative Regions, People’s Republic of China; 3State Key Laboratory of Brain and Cognitive Sciences, the University of Hong Kong, Hong Kong Special Administrative Regions, People’s Republic of China; 4Sleep Medicine Center, West China Hospital, Sichuan University, Chengdu, People’s Republic of China; 5Department of Neurology, West China Hospital, Sichuan University, Chengdu, People’s Republic of China*These authors contributed equally to this workCorrespondence: Junying Zhou, Sleep Medicine Center, West China Hospital, Sichuan University, 28 Dian Xin Nan Jie, Chengdu, Sichuan Province, People’s Republic of China, Email zhoujy2016scu.edu.cnObjective: This study aimed to determine the prevalence of chronic pain and its risk factors in patients with obstructive sleep apnea (OSA).Methods: A total of 145 patients diagnosed with OSA were consecutively recruited from the Sleep Medicine Center in West China Hospital. All patients were divided into two groups including OSA with and without chronic pain. They were assessed the subjective sleep (Pittsburgh Sleep Quality Index, Insomnia Severity Index), objective sleep (polysomnography), mood symptoms (Hamilton Depression Rating Scale, Hamilton Anxiety Rating Scale), and pain characteristics (Short-Form McGill Pain Questionnaire). Demographic, clinical, subjective and objective sleep parameters were compared between OSA patients with and without chronic pain. Binary logistic regression models and linear regression models were used to examine the risk factors of chronic pain in OSA.Results: Fifty-five (37.9%) patients with OSA were diagnosed with chronic pain. There were more severe subjective sleep disruption and symptoms of anxiety and depression in patients with chronic pain compared to those without chronic pain. After controlling for potential confounders, poor subjective sleep quality and severe insomnia and mood disorders (all ps < 0.05), but not objective sleep fragmentation or nocturnal hypoxemia (all ps < 0.05) were associated with the increased risk of pain and pain intensity, respectively.Conclusion: More than one-third of patients with OSA had chronic pain. Subjective sleep disruption and mood disorders are the risk factors of chronic pain in OSA. Our findings suggest that subjective sleep quality should be valued highly in the relationship between OSA and pain.Keywords: obstructive sleep apnea, subjective sleep disruption, insomnia, anxiety, depression, chronic pain |
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title_short |
Subjective Sleep Disruption and Mood Disorders are Associated with the Risk of Chronic Pain in Patients with Obstructive Sleep Apnea |
url |
https://doaj.org/article/90edbc5f88cd4152a8acfdcdc26e9456 https://www.dovepress.com/subjective-sleep-disruption-and-mood-disorders-are-associated-with-the-peer-reviewed-fulltext-article-NSS https://doaj.org/toc/1179-1608 |
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