Caracterização de cepas do Trypanosoma cruzi isoladas de doentes nos quais foi realizado transplante de coração

Três cepas do Trypanosoma cruzi foram, isoladas de pacientes com doença de Chagas crônica, receptores de coração por meio de tra?isplante. Houve caracterização delas através de modelo experimental baseado no emprego de camundongos, com avaliação de parasitismo, mortalidade e intensidade da inflamaçã...
Ausführliche Beschreibung

Gespeichert in:

Autor*in:	Perla Natalia Bustos Lanura [verfasserIn] Luís Matsubara [verfasserIn] Vicente Amato Neto [verfasserIn] Masayuki Okumura [verfasserIn] Edimar Alcides Bocchi [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	1995

Schlagwörter:	Doença de Chagas crônica Transplante de coração Cepas do Trypanosoma cruzi Caracterização Chronic Chagas' disease Heart transplantation Strain characteristics of Trypanosoma cruzi

Übergeordnetes Werk:	In: Revista da Sociedade Brasileira de Medicina Tropical - Sociedade Brasileira de Medicina Tropical (SBMT), 2004, 28(1995), 4, Seite 351-356
Übergeordnetes Werk:	volume:28 ; year:1995 ; number:4 ; pages:351-356

Links:	Link aufrufen Link aufrufen Journal toc Journal toc

Katalog-ID:	DOAJ029040132

Internformat


LEADER	01000caa a22002652 4500
001	DOAJ029040132
003	DE-627
005	20230307132537.0
007	cr uuu---uuuuu
008	230226s1995 xx \|\|\|\|\|o 00\| \|\|eng c
035			\|a (DE-627)DOAJ029040132
035			\|a (DE-599)DOAJb26f6ff06a3b4ab2821c429782849767
040			\|a DE-627 \|b ger \|c DE-627 \|e rakwb
041			\|a eng
050		0	\|a RC955-962
100	0		\|a Perla Natalia Bustos Lanura \|e verfasserin \|4 aut
245	1	0	\|a Caracterização de cepas do Trypanosoma cruzi isoladas de doentes nos quais foi realizado transplante de coração
264		1	\|c 1995
336			\|a Text \|b txt \|2 rdacontent
337			\|a Computermedien \|b c \|2 rdamedia
338			\|a Online-Ressource \|b cr \|2 rdacarrier
520			\|a Três cepas do Trypanosoma cruzi foram, isoladas de pacientes com doença de Chagas crônica, receptores de coração por meio de tra?isplante. Houve caracterização delas através de modelo experimental baseado no emprego de camundongos, com avaliação de parasitismo, mortalidade e intensidade da inflamação no coração, além de análise do grau de parasitismo nesse órgão. Como controle, teve lugar comparação com o comportamento da já bem conhecida cepa Y. Ficaram caracterizadas atuações diferentes das cepas, ao serem valorizados os parâmetros citados, sem correlação rigorosa com as evoluções pós-transplantes, que sofrem a influência de vários fatores, entre os quais podem estar particularidades vinculadas ao parasitismo.<br<Three strains of Trypanosoma cruzi were isolated from Chagas' disease patients transplanted for heart failure, after cardiac transplantation, and were studied in an experimental model of Chagas' disease, in mice, with evaluation of parasitic load, mortality and extension of inflammatory infiltrates in the heart. These parameters were compared with the standard strain Y. The strains had differences in the studied parameters, but there was no clear relationship between those and post-transplant evolution of the patients. Probably the clinical response is multifactorial and derives only in part from biological characteristics of the infecting T. cruzi strain, as measured in our model.
650		4	\|a Doença de Chagas crônica
650		4	\|a Transplante de coração
650		4	\|a Cepas do Trypanosoma cruzi
650		4	\|a Caracterização
650		4	\|a Chronic Chagas' disease
650		4	\|a Heart transplantation
650		4	\|a Strain characteristics of Trypanosoma cruzi
653		0	\|a Arctic medicine. Tropical medicine
700	0		\|a Luís Matsubara \|e verfasserin \|4 aut
700	0		\|a Vicente Amato Neto \|e verfasserin \|4 aut
700	0		\|a Masayuki Okumura \|e verfasserin \|4 aut
700	0		\|a Edimar Alcides Bocchi \|e verfasserin \|4 aut
773	0	8	\|i In \|t Revista da Sociedade Brasileira de Medicina Tropical \|d Sociedade Brasileira de Medicina Tropical (SBMT), 2004 \|g 28(1995), 4, Seite 351-356 \|w (DE-627)324614918 \|w (DE-600)2028921-2 \|x 16789849 \|7 nnns
773	1	8	\|g volume:28 \|g year:1995 \|g number:4 \|g pages:351-356
856	4	0	\|u https://doaj.org/article/b26f6ff06a3b4ab2821c429782849767 \|z kostenfrei
856	4	0	\|u http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86821995000400008 \|z kostenfrei
856	4	2	\|u https://doaj.org/toc/0037-8682 \|y Journal toc \|z kostenfrei
856	4	2	\|u https://doaj.org/toc/1678-9849 \|y Journal toc \|z kostenfrei
912			\|a GBV_USEFLAG_A
912			\|a SYSFLAG_A
912			\|a GBV_DOAJ
912			\|a GBV_ILN_20
912			\|a GBV_ILN_22
912			\|a GBV_ILN_23
912			\|a GBV_ILN_24
912			\|a GBV_ILN_31
912			\|a GBV_ILN_39
912			\|a GBV_ILN_40
912			\|a GBV_ILN_60
912			\|a GBV_ILN_62
912			\|a GBV_ILN_63
912			\|a GBV_ILN_65
912			\|a GBV_ILN_69
912			\|a GBV_ILN_73
912			\|a GBV_ILN_74
912			\|a GBV_ILN_95
912			\|a GBV_ILN_105
912			\|a GBV_ILN_110
912			\|a GBV_ILN_151
912			\|a GBV_ILN_161
912			\|a GBV_ILN_170
912			\|a GBV_ILN_206
912			\|a GBV_ILN_213
912			\|a GBV_ILN_230
912			\|a GBV_ILN_285
912			\|a GBV_ILN_293
912			\|a GBV_ILN_602
912			\|a GBV_ILN_2014
912			\|a GBV_ILN_4012
912			\|a GBV_ILN_4037
912			\|a GBV_ILN_4112
912			\|a GBV_ILN_4125
912			\|a GBV_ILN_4126
912			\|a GBV_ILN_4249
912			\|a GBV_ILN_4305
912			\|a GBV_ILN_4306
912			\|a GBV_ILN_4307
912			\|a GBV_ILN_4313
912			\|a GBV_ILN_4322
912			\|a GBV_ILN_4323
912			\|a GBV_ILN_4324
912			\|a GBV_ILN_4325
912			\|a GBV_ILN_4338
912			\|a GBV_ILN_4367
912			\|a GBV_ILN_4700
951			\|a AR
952			\|d 28 \|j 1995 \|e 4 \|h 351-356

Indexfelder

author_variant	p n b l pnbl l m lm v a n van m o mo e a b eab
matchkey_str	article:16789849:1995----::aatrzoeeadtyaooarzioaaddetsoqasora
hierarchy_sort_str	1995
callnumber-subject-code	RC
publishDate	1995
allfields	(DE-627)DOAJ029040132 (DE-599)DOAJb26f6ff06a3b4ab2821c429782849767 DE-627 ger DE-627 rakwb eng RC955-962 Perla Natalia Bustos Lanura verfasserin aut Caracterização de cepas do Trypanosoma cruzi isoladas de doentes nos quais foi realizado transplante de coração 1995 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Três cepas do Trypanosoma cruzi foram, isoladas de pacientes com doença de Chagas crônica, receptores de coração por meio de tra?isplante. Houve caracterização delas através de modelo experimental baseado no emprego de camundongos, com avaliação de parasitismo, mortalidade e intensidade da inflamação no coração, além de análise do grau de parasitismo nesse órgão. Como controle, teve lugar comparação com o comportamento da já bem conhecida cepa Y. Ficaram caracterizadas atuações diferentes das cepas, ao serem valorizados os parâmetros citados, sem correlação rigorosa com as evoluções pós-transplantes, que sofrem a influência de vários fatores, entre os quais podem estar particularidades vinculadas ao parasitismo.<br<Three strains of Trypanosoma cruzi were isolated from Chagas' disease patients transplanted for heart failure, after cardiac transplantation, and were studied in an experimental model of Chagas' disease, in mice, with evaluation of parasitic load, mortality and extension of inflammatory infiltrates in the heart. These parameters were compared with the standard strain Y. The strains had differences in the studied parameters, but there was no clear relationship between those and post-transplant evolution of the patients. Probably the clinical response is multifactorial and derives only in part from biological characteristics of the infecting T. cruzi strain, as measured in our model. Doença de Chagas crônica Transplante de coração Cepas do Trypanosoma cruzi Caracterização Chronic Chagas' disease Heart transplantation Strain characteristics of Trypanosoma cruzi Arctic medicine. Tropical medicine Luís Matsubara verfasserin aut Vicente Amato Neto verfasserin aut Masayuki Okumura verfasserin aut Edimar Alcides Bocchi verfasserin aut In Revista da Sociedade Brasileira de Medicina Tropical Sociedade Brasileira de Medicina Tropical (SBMT), 2004 28(1995), 4, Seite 351-356 (DE-627)324614918 (DE-600)2028921-2 16789849 nnns volume:28 year:1995 number:4 pages:351-356 https://doaj.org/article/b26f6ff06a3b4ab2821c429782849767 kostenfrei http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86821995000400008 kostenfrei https://doaj.org/toc/0037-8682 Journal toc kostenfrei https://doaj.org/toc/1678-9849 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 28 1995 4 351-356
spelling	(DE-627)DOAJ029040132 (DE-599)DOAJb26f6ff06a3b4ab2821c429782849767 DE-627 ger DE-627 rakwb eng RC955-962 Perla Natalia Bustos Lanura verfasserin aut Caracterização de cepas do Trypanosoma cruzi isoladas de doentes nos quais foi realizado transplante de coração 1995 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Três cepas do Trypanosoma cruzi foram, isoladas de pacientes com doença de Chagas crônica, receptores de coração por meio de tra?isplante. Houve caracterização delas através de modelo experimental baseado no emprego de camundongos, com avaliação de parasitismo, mortalidade e intensidade da inflamação no coração, além de análise do grau de parasitismo nesse órgão. Como controle, teve lugar comparação com o comportamento da já bem conhecida cepa Y. Ficaram caracterizadas atuações diferentes das cepas, ao serem valorizados os parâmetros citados, sem correlação rigorosa com as evoluções pós-transplantes, que sofrem a influência de vários fatores, entre os quais podem estar particularidades vinculadas ao parasitismo.<br<Three strains of Trypanosoma cruzi were isolated from Chagas' disease patients transplanted for heart failure, after cardiac transplantation, and were studied in an experimental model of Chagas' disease, in mice, with evaluation of parasitic load, mortality and extension of inflammatory infiltrates in the heart. These parameters were compared with the standard strain Y. The strains had differences in the studied parameters, but there was no clear relationship between those and post-transplant evolution of the patients. Probably the clinical response is multifactorial and derives only in part from biological characteristics of the infecting T. cruzi strain, as measured in our model. Doença de Chagas crônica Transplante de coração Cepas do Trypanosoma cruzi Caracterização Chronic Chagas' disease Heart transplantation Strain characteristics of Trypanosoma cruzi Arctic medicine. Tropical medicine Luís Matsubara verfasserin aut Vicente Amato Neto verfasserin aut Masayuki Okumura verfasserin aut Edimar Alcides Bocchi verfasserin aut In Revista da Sociedade Brasileira de Medicina Tropical Sociedade Brasileira de Medicina Tropical (SBMT), 2004 28(1995), 4, Seite 351-356 (DE-627)324614918 (DE-600)2028921-2 16789849 nnns volume:28 year:1995 number:4 pages:351-356 https://doaj.org/article/b26f6ff06a3b4ab2821c429782849767 kostenfrei http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86821995000400008 kostenfrei https://doaj.org/toc/0037-8682 Journal toc kostenfrei https://doaj.org/toc/1678-9849 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 28 1995 4 351-356
allfields_unstemmed	(DE-627)DOAJ029040132 (DE-599)DOAJb26f6ff06a3b4ab2821c429782849767 DE-627 ger DE-627 rakwb eng RC955-962 Perla Natalia Bustos Lanura verfasserin aut Caracterização de cepas do Trypanosoma cruzi isoladas de doentes nos quais foi realizado transplante de coração 1995 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Três cepas do Trypanosoma cruzi foram, isoladas de pacientes com doença de Chagas crônica, receptores de coração por meio de tra?isplante. Houve caracterização delas através de modelo experimental baseado no emprego de camundongos, com avaliação de parasitismo, mortalidade e intensidade da inflamação no coração, além de análise do grau de parasitismo nesse órgão. Como controle, teve lugar comparação com o comportamento da já bem conhecida cepa Y. Ficaram caracterizadas atuações diferentes das cepas, ao serem valorizados os parâmetros citados, sem correlação rigorosa com as evoluções pós-transplantes, que sofrem a influência de vários fatores, entre os quais podem estar particularidades vinculadas ao parasitismo.<br<Three strains of Trypanosoma cruzi were isolated from Chagas' disease patients transplanted for heart failure, after cardiac transplantation, and were studied in an experimental model of Chagas' disease, in mice, with evaluation of parasitic load, mortality and extension of inflammatory infiltrates in the heart. These parameters were compared with the standard strain Y. The strains had differences in the studied parameters, but there was no clear relationship between those and post-transplant evolution of the patients. Probably the clinical response is multifactorial and derives only in part from biological characteristics of the infecting T. cruzi strain, as measured in our model. Doença de Chagas crônica Transplante de coração Cepas do Trypanosoma cruzi Caracterização Chronic Chagas' disease Heart transplantation Strain characteristics of Trypanosoma cruzi Arctic medicine. Tropical medicine Luís Matsubara verfasserin aut Vicente Amato Neto verfasserin aut Masayuki Okumura verfasserin aut Edimar Alcides Bocchi verfasserin aut In Revista da Sociedade Brasileira de Medicina Tropical Sociedade Brasileira de Medicina Tropical (SBMT), 2004 28(1995), 4, Seite 351-356 (DE-627)324614918 (DE-600)2028921-2 16789849 nnns volume:28 year:1995 number:4 pages:351-356 https://doaj.org/article/b26f6ff06a3b4ab2821c429782849767 kostenfrei http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86821995000400008 kostenfrei https://doaj.org/toc/0037-8682 Journal toc kostenfrei https://doaj.org/toc/1678-9849 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 28 1995 4 351-356
allfieldsGer	(DE-627)DOAJ029040132 (DE-599)DOAJb26f6ff06a3b4ab2821c429782849767 DE-627 ger DE-627 rakwb eng RC955-962 Perla Natalia Bustos Lanura verfasserin aut Caracterização de cepas do Trypanosoma cruzi isoladas de doentes nos quais foi realizado transplante de coração 1995 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Três cepas do Trypanosoma cruzi foram, isoladas de pacientes com doença de Chagas crônica, receptores de coração por meio de tra?isplante. Houve caracterização delas através de modelo experimental baseado no emprego de camundongos, com avaliação de parasitismo, mortalidade e intensidade da inflamação no coração, além de análise do grau de parasitismo nesse órgão. Como controle, teve lugar comparação com o comportamento da já bem conhecida cepa Y. Ficaram caracterizadas atuações diferentes das cepas, ao serem valorizados os parâmetros citados, sem correlação rigorosa com as evoluções pós-transplantes, que sofrem a influência de vários fatores, entre os quais podem estar particularidades vinculadas ao parasitismo.<br<Three strains of Trypanosoma cruzi were isolated from Chagas' disease patients transplanted for heart failure, after cardiac transplantation, and were studied in an experimental model of Chagas' disease, in mice, with evaluation of parasitic load, mortality and extension of inflammatory infiltrates in the heart. These parameters were compared with the standard strain Y. The strains had differences in the studied parameters, but there was no clear relationship between those and post-transplant evolution of the patients. Probably the clinical response is multifactorial and derives only in part from biological characteristics of the infecting T. cruzi strain, as measured in our model. Doença de Chagas crônica Transplante de coração Cepas do Trypanosoma cruzi Caracterização Chronic Chagas' disease Heart transplantation Strain characteristics of Trypanosoma cruzi Arctic medicine. Tropical medicine Luís Matsubara verfasserin aut Vicente Amato Neto verfasserin aut Masayuki Okumura verfasserin aut Edimar Alcides Bocchi verfasserin aut In Revista da Sociedade Brasileira de Medicina Tropical Sociedade Brasileira de Medicina Tropical (SBMT), 2004 28(1995), 4, Seite 351-356 (DE-627)324614918 (DE-600)2028921-2 16789849 nnns volume:28 year:1995 number:4 pages:351-356 https://doaj.org/article/b26f6ff06a3b4ab2821c429782849767 kostenfrei http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86821995000400008 kostenfrei https://doaj.org/toc/0037-8682 Journal toc kostenfrei https://doaj.org/toc/1678-9849 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 28 1995 4 351-356
allfieldsSound	(DE-627)DOAJ029040132 (DE-599)DOAJb26f6ff06a3b4ab2821c429782849767 DE-627 ger DE-627 rakwb eng RC955-962 Perla Natalia Bustos Lanura verfasserin aut Caracterização de cepas do Trypanosoma cruzi isoladas de doentes nos quais foi realizado transplante de coração 1995 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Três cepas do Trypanosoma cruzi foram, isoladas de pacientes com doença de Chagas crônica, receptores de coração por meio de tra?isplante. Houve caracterização delas através de modelo experimental baseado no emprego de camundongos, com avaliação de parasitismo, mortalidade e intensidade da inflamação no coração, além de análise do grau de parasitismo nesse órgão. Como controle, teve lugar comparação com o comportamento da já bem conhecida cepa Y. Ficaram caracterizadas atuações diferentes das cepas, ao serem valorizados os parâmetros citados, sem correlação rigorosa com as evoluções pós-transplantes, que sofrem a influência de vários fatores, entre os quais podem estar particularidades vinculadas ao parasitismo.<br<Three strains of Trypanosoma cruzi were isolated from Chagas' disease patients transplanted for heart failure, after cardiac transplantation, and were studied in an experimental model of Chagas' disease, in mice, with evaluation of parasitic load, mortality and extension of inflammatory infiltrates in the heart. These parameters were compared with the standard strain Y. The strains had differences in the studied parameters, but there was no clear relationship between those and post-transplant evolution of the patients. Probably the clinical response is multifactorial and derives only in part from biological characteristics of the infecting T. cruzi strain, as measured in our model. Doença de Chagas crônica Transplante de coração Cepas do Trypanosoma cruzi Caracterização Chronic Chagas' disease Heart transplantation Strain characteristics of Trypanosoma cruzi Arctic medicine. Tropical medicine Luís Matsubara verfasserin aut Vicente Amato Neto verfasserin aut Masayuki Okumura verfasserin aut Edimar Alcides Bocchi verfasserin aut In Revista da Sociedade Brasileira de Medicina Tropical Sociedade Brasileira de Medicina Tropical (SBMT), 2004 28(1995), 4, Seite 351-356 (DE-627)324614918 (DE-600)2028921-2 16789849 nnns volume:28 year:1995 number:4 pages:351-356 https://doaj.org/article/b26f6ff06a3b4ab2821c429782849767 kostenfrei http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86821995000400008 kostenfrei https://doaj.org/toc/0037-8682 Journal toc kostenfrei https://doaj.org/toc/1678-9849 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 28 1995 4 351-356
language	English
source	In Revista da Sociedade Brasileira de Medicina Tropical 28(1995), 4, Seite 351-356 volume:28 year:1995 number:4 pages:351-356
sourceStr	In Revista da Sociedade Brasileira de Medicina Tropical 28(1995), 4, Seite 351-356 volume:28 year:1995 number:4 pages:351-356
format_phy_str_mv	Article
institution	findex.gbv.de
topic_facet	Doença de Chagas crônica Transplante de coração Cepas do Trypanosoma cruzi Caracterização Chronic Chagas' disease Heart transplantation Strain characteristics of Trypanosoma cruzi Arctic medicine. Tropical medicine
isfreeaccess_bool	true
container_title	Revista da Sociedade Brasileira de Medicina Tropical
authorswithroles_txt_mv	Perla Natalia Bustos Lanura @@aut@@ Luís Matsubara @@aut@@ Vicente Amato Neto @@aut@@ Masayuki Okumura @@aut@@ Edimar Alcides Bocchi @@aut@@
publishDateDaySort_date	1995-01-01T00:00:00Z
hierarchy_top_id	324614918
id	DOAJ029040132
language_de	englisch
fullrecord	<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000caa a22002652 4500</leader><controlfield tag="001">DOAJ029040132</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20230307132537.0</controlfield><controlfield tag="007">cr uuu---uuuuu</controlfield><controlfield tag="008">230226s1995 xx \|\|\|\|\|o 00\| \|\|eng c</controlfield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)DOAJ029040132</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-599)DOAJb26f6ff06a3b4ab2821c429782849767</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="041" ind1=" " ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="050" ind1=" " ind2="0"><subfield code="a">RC955-962</subfield></datafield><datafield tag="100" ind1="0" ind2=" "><subfield code="a">Perla Natalia Bustos Lanura</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Caracterização de cepas do Trypanosoma cruzi isoladas de doentes nos quais foi realizado transplante de coração</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="c">1995</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">Text</subfield><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">Computermedien</subfield><subfield code="b">c</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">Online-Ressource</subfield><subfield code="b">cr</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">Três cepas do Trypanosoma cruzi foram, isoladas de pacientes com doença de Chagas crônica, receptores de coração por meio de tra?isplante. Houve caracterização delas através de modelo experimental baseado no emprego de camundongos, com avaliação de parasitismo, mortalidade e intensidade da inflamação no coração, além de análise do grau de parasitismo nesse órgão. Como controle, teve lugar comparação com o comportamento da já bem conhecida cepa Y. Ficaram caracterizadas atuações diferentes das cepas, ao serem valorizados os parâmetros citados, sem correlação rigorosa com as evoluções pós-transplantes, que sofrem a influência de vários fatores, entre os quais podem estar particularidades vinculadas ao parasitismo.<br<Three strains of Trypanosoma cruzi were isolated from Chagas' disease patients transplanted for heart failure, after cardiac transplantation, and were studied in an experimental model of Chagas' disease, in mice, with evaluation of parasitic load, mortality and extension of inflammatory infiltrates in the heart. These parameters were compared with the standard strain Y. The strains had differences in the studied parameters, but there was no clear relationship between those and post-transplant evolution of the patients. Probably the clinical response is multifactorial and derives only in part from biological characteristics of the infecting T. cruzi strain, as measured in our model.</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Doença de Chagas crônica</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Transplante de coração</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Cepas do Trypanosoma cruzi</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Caracterização</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Chronic Chagas' disease</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Heart transplantation</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Strain characteristics of Trypanosoma cruzi</subfield></datafield><datafield tag="653" ind1=" " ind2="0"><subfield code="a">Arctic medicine. Tropical medicine</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Luís Matsubara</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Vicente Amato Neto</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Masayuki Okumura</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Edimar Alcides Bocchi</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="773" ind1="0" ind2="8"><subfield code="i">In</subfield><subfield code="t">Revista da Sociedade Brasileira de Medicina Tropical</subfield><subfield code="d">Sociedade Brasileira de Medicina Tropical (SBMT), 2004</subfield><subfield code="g">28(1995), 4, Seite 351-356</subfield><subfield code="w">(DE-627)324614918</subfield><subfield code="w">(DE-600)2028921-2</subfield><subfield code="x">16789849</subfield><subfield code="7">nnns</subfield></datafield><datafield tag="773" ind1="1" ind2="8"><subfield code="g">volume:28</subfield><subfield code="g">year:1995</subfield><subfield code="g">number:4</subfield><subfield code="g">pages:351-356</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">https://doaj.org/article/b26f6ff06a3b4ab2821c429782849767</subfield><subfield code="z">kostenfrei</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86821995000400008</subfield><subfield code="z">kostenfrei</subfield></datafield><datafield tag="856" ind1="4" ind2="2"><subfield code="u">https://doaj.org/toc/0037-8682</subfield><subfield code="y">Journal toc</subfield><subfield code="z">kostenfrei</subfield></datafield><datafield tag="856" ind1="4" ind2="2"><subfield code="u">https://doaj.org/toc/1678-9849</subfield><subfield code="y">Journal toc</subfield><subfield code="z">kostenfrei</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_USEFLAG_A</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">SYSFLAG_A</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_DOAJ</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_20</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_22</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_23</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_24</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_31</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_39</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_40</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_60</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_62</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_63</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_65</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_69</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_73</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_74</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_95</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_105</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_110</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_151</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_161</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_170</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_206</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_213</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_230</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_285</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_293</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_602</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2014</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4012</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4037</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4112</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4125</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4126</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4249</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4305</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4306</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4307</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4313</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4322</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4323</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4324</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4325</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4338</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4367</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4700</subfield></datafield><datafield tag="951" ind1=" " ind2=" "><subfield code="a">AR</subfield></datafield><datafield tag="952" ind1=" " ind2=" "><subfield code="d">28</subfield><subfield code="j">1995</subfield><subfield code="e">4</subfield><subfield code="h">351-356</subfield></datafield></record></collection>
callnumber-first	R - Medicine
author	Perla Natalia Bustos Lanura
spellingShingle	Perla Natalia Bustos Lanura misc RC955-962 misc Doença de Chagas crônica misc Transplante de coração misc Cepas do Trypanosoma cruzi misc Caracterização misc Chronic Chagas' disease misc Heart transplantation misc Strain characteristics of Trypanosoma cruzi misc Arctic medicine. Tropical medicine Caracterização de cepas do Trypanosoma cruzi isoladas de doentes nos quais foi realizado transplante de coração
authorStr	Perla Natalia Bustos Lanura
ppnlink_with_tag_str_mv	@@773@@(DE-627)324614918
format	electronic Article
delete_txt_mv	keep
author_role	aut aut aut aut aut
collection	DOAJ
remote_str	true
callnumber-label	RC955-962
illustrated	Not Illustrated
issn	16789849
topic_title	RC955-962 Caracterização de cepas do Trypanosoma cruzi isoladas de doentes nos quais foi realizado transplante de coração Doença de Chagas crônica Transplante de coração Cepas do Trypanosoma cruzi Caracterização Chronic Chagas' disease Heart transplantation Strain characteristics of Trypanosoma cruzi
topic	misc RC955-962 misc Doença de Chagas crônica misc Transplante de coração misc Cepas do Trypanosoma cruzi misc Caracterização misc Chronic Chagas' disease misc Heart transplantation misc Strain characteristics of Trypanosoma cruzi misc Arctic medicine. Tropical medicine
topic_unstemmed	misc RC955-962 misc Doença de Chagas crônica misc Transplante de coração misc Cepas do Trypanosoma cruzi misc Caracterização misc Chronic Chagas' disease misc Heart transplantation misc Strain characteristics of Trypanosoma cruzi misc Arctic medicine. Tropical medicine
topic_browse	misc RC955-962 misc Doença de Chagas crônica misc Transplante de coração misc Cepas do Trypanosoma cruzi misc Caracterização misc Chronic Chagas' disease misc Heart transplantation misc Strain characteristics of Trypanosoma cruzi misc Arctic medicine. Tropical medicine
format_facet	Elektronische Aufsätze Aufsätze Elektronische Ressource
format_main_str_mv	Text Zeitschrift/Artikel
carriertype_str_mv	cr
hierarchy_parent_title	Revista da Sociedade Brasileira de Medicina Tropical
hierarchy_parent_id	324614918
hierarchy_top_title	Revista da Sociedade Brasileira de Medicina Tropical
isfreeaccess_txt	true
familylinks_str_mv	(DE-627)324614918 (DE-600)2028921-2
title	Caracterização de cepas do Trypanosoma cruzi isoladas de doentes nos quais foi realizado transplante de coração
ctrlnum	(DE-627)DOAJ029040132 (DE-599)DOAJb26f6ff06a3b4ab2821c429782849767
title_full	Caracterização de cepas do Trypanosoma cruzi isoladas de doentes nos quais foi realizado transplante de coração
author_sort	Perla Natalia Bustos Lanura
journal	Revista da Sociedade Brasileira de Medicina Tropical
journalStr	Revista da Sociedade Brasileira de Medicina Tropical
callnumber-first-code	R
lang_code	eng
isOA_bool	true
recordtype	marc
publishDateSort	1995
contenttype_str_mv	txt
container_start_page	351
author_browse	Perla Natalia Bustos Lanura Luís Matsubara Vicente Amato Neto Masayuki Okumura Edimar Alcides Bocchi
container_volume	28
class	RC955-962
format_se	Elektronische Aufsätze
author-letter	Perla Natalia Bustos Lanura
author2-role	verfasserin
title_sort	caracterização de cepas do trypanosoma cruzi isoladas de doentes nos quais foi realizado transplante de coração
callnumber	RC955-962
title_auth	Caracterização de cepas do Trypanosoma cruzi isoladas de doentes nos quais foi realizado transplante de coração
abstract	Três cepas do Trypanosoma cruzi foram, isoladas de pacientes com doença de Chagas crônica, receptores de coração por meio de tra?isplante. Houve caracterização delas através de modelo experimental baseado no emprego de camundongos, com avaliação de parasitismo, mortalidade e intensidade da inflamação no coração, além de análise do grau de parasitismo nesse órgão. Como controle, teve lugar comparação com o comportamento da já bem conhecida cepa Y. Ficaram caracterizadas atuações diferentes das cepas, ao serem valorizados os parâmetros citados, sem correlação rigorosa com as evoluções pós-transplantes, que sofrem a influência de vários fatores, entre os quais podem estar particularidades vinculadas ao parasitismo.<br<Three strains of Trypanosoma cruzi were isolated from Chagas' disease patients transplanted for heart failure, after cardiac transplantation, and were studied in an experimental model of Chagas' disease, in mice, with evaluation of parasitic load, mortality and extension of inflammatory infiltrates in the heart. These parameters were compared with the standard strain Y. The strains had differences in the studied parameters, but there was no clear relationship between those and post-transplant evolution of the patients. Probably the clinical response is multifactorial and derives only in part from biological characteristics of the infecting T. cruzi strain, as measured in our model.
abstractGer	Três cepas do Trypanosoma cruzi foram, isoladas de pacientes com doença de Chagas crônica, receptores de coração por meio de tra?isplante. Houve caracterização delas através de modelo experimental baseado no emprego de camundongos, com avaliação de parasitismo, mortalidade e intensidade da inflamação no coração, além de análise do grau de parasitismo nesse órgão. Como controle, teve lugar comparação com o comportamento da já bem conhecida cepa Y. Ficaram caracterizadas atuações diferentes das cepas, ao serem valorizados os parâmetros citados, sem correlação rigorosa com as evoluções pós-transplantes, que sofrem a influência de vários fatores, entre os quais podem estar particularidades vinculadas ao parasitismo.<br<Three strains of Trypanosoma cruzi were isolated from Chagas' disease patients transplanted for heart failure, after cardiac transplantation, and were studied in an experimental model of Chagas' disease, in mice, with evaluation of parasitic load, mortality and extension of inflammatory infiltrates in the heart. These parameters were compared with the standard strain Y. The strains had differences in the studied parameters, but there was no clear relationship between those and post-transplant evolution of the patients. Probably the clinical response is multifactorial and derives only in part from biological characteristics of the infecting T. cruzi strain, as measured in our model.
abstract_unstemmed	Três cepas do Trypanosoma cruzi foram, isoladas de pacientes com doença de Chagas crônica, receptores de coração por meio de tra?isplante. Houve caracterização delas através de modelo experimental baseado no emprego de camundongos, com avaliação de parasitismo, mortalidade e intensidade da inflamação no coração, além de análise do grau de parasitismo nesse órgão. Como controle, teve lugar comparação com o comportamento da já bem conhecida cepa Y. Ficaram caracterizadas atuações diferentes das cepas, ao serem valorizados os parâmetros citados, sem correlação rigorosa com as evoluções pós-transplantes, que sofrem a influência de vários fatores, entre os quais podem estar particularidades vinculadas ao parasitismo.<br<Three strains of Trypanosoma cruzi were isolated from Chagas' disease patients transplanted for heart failure, after cardiac transplantation, and were studied in an experimental model of Chagas' disease, in mice, with evaluation of parasitic load, mortality and extension of inflammatory infiltrates in the heart. These parameters were compared with the standard strain Y. The strains had differences in the studied parameters, but there was no clear relationship between those and post-transplant evolution of the patients. Probably the clinical response is multifactorial and derives only in part from biological characteristics of the infecting T. cruzi strain, as measured in our model.
collection_details	GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700
container_issue	4
title_short	Caracterização de cepas do Trypanosoma cruzi isoladas de doentes nos quais foi realizado transplante de coração
url	https://doaj.org/article/b26f6ff06a3b4ab2821c429782849767 http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86821995000400008 https://doaj.org/toc/0037-8682 https://doaj.org/toc/1678-9849
remote_bool	true
author2	Luís Matsubara Vicente Amato Neto Masayuki Okumura Edimar Alcides Bocchi
author2Str	Luís Matsubara Vicente Amato Neto Masayuki Okumura Edimar Alcides Bocchi
ppnlink	324614918
callnumber-subject	RC - Internal Medicine
mediatype_str_mv	c
isOA_txt	true
hochschulschrift_bool	false
callnumber-a	RC955-962
up_date	2024-07-03T20:49:03.567Z
_version_	1803592394151559168
fullrecord_marcxml	<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01000caa a22002652 4500</leader><controlfield tag="001">DOAJ029040132</controlfield><controlfield tag="003">DE-627</controlfield><controlfield tag="005">20230307132537.0</controlfield><controlfield tag="007">cr uuu---uuuuu</controlfield><controlfield tag="008">230226s1995 xx \|\|\|\|\|o 00\| \|\|eng c</controlfield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-627)DOAJ029040132</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-599)DOAJb26f6ff06a3b4ab2821c429782849767</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-627</subfield><subfield code="b">ger</subfield><subfield code="c">DE-627</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="041" ind1=" " ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="050" ind1=" " ind2="0"><subfield code="a">RC955-962</subfield></datafield><datafield tag="100" ind1="0" ind2=" "><subfield code="a">Perla Natalia Bustos Lanura</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Caracterização de cepas do Trypanosoma cruzi isoladas de doentes nos quais foi realizado transplante de coração</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="c">1995</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">Text</subfield><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">Computermedien</subfield><subfield code="b">c</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">Online-Ressource</subfield><subfield code="b">cr</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">Três cepas do Trypanosoma cruzi foram, isoladas de pacientes com doença de Chagas crônica, receptores de coração por meio de tra?isplante. Houve caracterização delas através de modelo experimental baseado no emprego de camundongos, com avaliação de parasitismo, mortalidade e intensidade da inflamação no coração, além de análise do grau de parasitismo nesse órgão. Como controle, teve lugar comparação com o comportamento da já bem conhecida cepa Y. Ficaram caracterizadas atuações diferentes das cepas, ao serem valorizados os parâmetros citados, sem correlação rigorosa com as evoluções pós-transplantes, que sofrem a influência de vários fatores, entre os quais podem estar particularidades vinculadas ao parasitismo.<br<Three strains of Trypanosoma cruzi were isolated from Chagas' disease patients transplanted for heart failure, after cardiac transplantation, and were studied in an experimental model of Chagas' disease, in mice, with evaluation of parasitic load, mortality and extension of inflammatory infiltrates in the heart. These parameters were compared with the standard strain Y. The strains had differences in the studied parameters, but there was no clear relationship between those and post-transplant evolution of the patients. Probably the clinical response is multifactorial and derives only in part from biological characteristics of the infecting T. cruzi strain, as measured in our model.</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Doença de Chagas crônica</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Transplante de coração</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Cepas do Trypanosoma cruzi</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Caracterização</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Chronic Chagas' disease</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Heart transplantation</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Strain characteristics of Trypanosoma cruzi</subfield></datafield><datafield tag="653" ind1=" " ind2="0"><subfield code="a">Arctic medicine. Tropical medicine</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Luís Matsubara</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Vicente Amato Neto</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Masayuki Okumura</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="700" ind1="0" ind2=" "><subfield code="a">Edimar Alcides Bocchi</subfield><subfield code="e">verfasserin</subfield><subfield code="4">aut</subfield></datafield><datafield tag="773" ind1="0" ind2="8"><subfield code="i">In</subfield><subfield code="t">Revista da Sociedade Brasileira de Medicina Tropical</subfield><subfield code="d">Sociedade Brasileira de Medicina Tropical (SBMT), 2004</subfield><subfield code="g">28(1995), 4, Seite 351-356</subfield><subfield code="w">(DE-627)324614918</subfield><subfield code="w">(DE-600)2028921-2</subfield><subfield code="x">16789849</subfield><subfield code="7">nnns</subfield></datafield><datafield tag="773" ind1="1" ind2="8"><subfield code="g">volume:28</subfield><subfield code="g">year:1995</subfield><subfield code="g">number:4</subfield><subfield code="g">pages:351-356</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">https://doaj.org/article/b26f6ff06a3b4ab2821c429782849767</subfield><subfield code="z">kostenfrei</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86821995000400008</subfield><subfield code="z">kostenfrei</subfield></datafield><datafield tag="856" ind1="4" ind2="2"><subfield code="u">https://doaj.org/toc/0037-8682</subfield><subfield code="y">Journal toc</subfield><subfield code="z">kostenfrei</subfield></datafield><datafield tag="856" ind1="4" ind2="2"><subfield code="u">https://doaj.org/toc/1678-9849</subfield><subfield code="y">Journal toc</subfield><subfield code="z">kostenfrei</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_USEFLAG_A</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">SYSFLAG_A</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_DOAJ</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_20</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_22</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_23</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_24</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_31</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_39</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_40</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_60</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_62</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_63</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_65</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_69</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_73</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_74</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_95</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_105</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_110</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_151</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_161</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_170</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_206</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_213</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_230</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_285</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_293</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_602</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_2014</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4012</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4037</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4112</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4125</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4126</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4249</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4305</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4306</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4307</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4313</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4322</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4323</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4324</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4325</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4338</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4367</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">GBV_ILN_4700</subfield></datafield><datafield tag="951" ind1=" " ind2=" "><subfield code="a">AR</subfield></datafield><datafield tag="952" ind1=" " ind2=" "><subfield code="d">28</subfield><subfield code="j">1995</subfield><subfield code="e">4</subfield><subfield code="h">351-356</subfield></datafield></record></collection>
score	7.401272

Nicht das Richtige dabei?

Schreiben Sie uns!

Caracterização de cepas do Trypanosoma cruzi isoladas de doentes nos quais foi realizado transplante de coração

Nicht das Richtige dabei?

Zugang & Verfügbarkeit

Vorhandene Bände

Nicht das Richtige dabei?