Using pulsed dye laser to treat sebaceous hyperplasia: comparison of short and long pulse-duration pulsed dye laser

Background: Pulsed dye laser (PDL) is effective in treating sebaceous hyperplasia (SH). However, only short pulse-duration PDL (SPDL) has been used in previous studies. Objectives: To determine whether long pulse-duration PDL (LPDL) can achieve comparable efficacy in treating SH with fewer side effe...
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Gespeichert in:

Autor*in:	Sheng-Pei Wang [verfasserIn] Ying-Jui Chang [verfasserIn] Ching-Chi Chi [verfasserIn] Shu-Hui Wang [verfasserIn] Tsung-Hua Tsai [verfasserIn]

Format:	E-Artikel
Sprache:	Englisch

Erschienen:	2017

Schlagwörter:	long pulse-duration pulsed dye laser sebaceous hyperplasia short pulse-duration pulsed dye laser

Übergeordnetes Werk:	In: Dermatologica Sinica - Wolters Kluwer Medknow Publications, 2017, 35(2017), 3, Seite 119-123
Übergeordnetes Werk:	volume:35 ; year:2017 ; number:3 ; pages:119-123

Links:	Link aufrufen Link aufrufen Link aufrufen Journal toc

DOI / URN:	10.1016/j.dsi.2017.03.004

Katalog-ID:	DOAJ029099927

Internformat


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520			\|a Background: Pulsed dye laser (PDL) is effective in treating sebaceous hyperplasia (SH). However, only short pulse-duration PDL (SPDL) has been used in previous studies. Objectives: To determine whether long pulse-duration PDL (LPDL) can achieve comparable efficacy in treating SH with fewer side effects versus SPDL. Methods: Eight patients with a total of 75 SH lesions were enrolled. Each SH lesion was randomized to be treated with two sessions of 595-nm SPDL with 0.45-millisecond pulse duration or 595-nm LPDL with 20-millisecond pulse duration. The second session was performed 4 weeks after the first session. Side effects including pain and post-treatment purpura were recorded. Follow-up examinations were conducted at 1 week and 4 weeks after the first session, and at 1 week, 4 weeks, and 8 weeks after the second session for repeated photography and assessing the diameter and thickness of each lesion, post-treatment purpura, and other adverse events. Results: All SH lesions responded to two sessions of PDL treatments. The reduction ratio of lesion diameter was 76.3% in the SPDL group and 70.0% in the LPDL group after two sessions of treatments (p = 0.644). The reduction ratio of lesion thickness was 79.6% in the SPDL group and 72.7% in the LPDL group after two sessions of treatment (p = 0.187). The mean intensity of pain was 3.13 on a 0–10-point scale for SPDL and 3.60 for LPDL (p = 0.660). The intensity of immediate post-treatment purpura was 4.13 on a 0–5-point scale for SPDL, and 1.80 for LPDL (p < 0.001). Some of the lesions treated by SPDL underwent an erosive stage. No scarring or discoloration was noted at 8 weeks after treatment. Conclusions: While SPDL and LPDL have comparable efficacy in treating SH after two sessions of treatment, LPDL can provide a shorter and aesthetically better recovery time.
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allfields	10.1016/j.dsi.2017.03.004 doi (DE-627)DOAJ029099927 (DE-599)DOAJ2bce41564f244bfe8e2790670be40ca8 DE-627 ger DE-627 rakwb eng RL1-803 Sheng-Pei Wang verfasserin aut Using pulsed dye laser to treat sebaceous hyperplasia: comparison of short and long pulse-duration pulsed dye laser 2017 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background: Pulsed dye laser (PDL) is effective in treating sebaceous hyperplasia (SH). However, only short pulse-duration PDL (SPDL) has been used in previous studies. Objectives: To determine whether long pulse-duration PDL (LPDL) can achieve comparable efficacy in treating SH with fewer side effects versus SPDL. Methods: Eight patients with a total of 75 SH lesions were enrolled. Each SH lesion was randomized to be treated with two sessions of 595-nm SPDL with 0.45-millisecond pulse duration or 595-nm LPDL with 20-millisecond pulse duration. The second session was performed 4 weeks after the first session. Side effects including pain and post-treatment purpura were recorded. Follow-up examinations were conducted at 1 week and 4 weeks after the first session, and at 1 week, 4 weeks, and 8 weeks after the second session for repeated photography and assessing the diameter and thickness of each lesion, post-treatment purpura, and other adverse events. Results: All SH lesions responded to two sessions of PDL treatments. The reduction ratio of lesion diameter was 76.3% in the SPDL group and 70.0% in the LPDL group after two sessions of treatments (p = 0.644). The reduction ratio of lesion thickness was 79.6% in the SPDL group and 72.7% in the LPDL group after two sessions of treatment (p = 0.187). The mean intensity of pain was 3.13 on a 0–10-point scale for SPDL and 3.60 for LPDL (p = 0.660). The intensity of immediate post-treatment purpura was 4.13 on a 0–5-point scale for SPDL, and 1.80 for LPDL (p < 0.001). Some of the lesions treated by SPDL underwent an erosive stage. No scarring or discoloration was noted at 8 weeks after treatment. Conclusions: While SPDL and LPDL have comparable efficacy in treating SH after two sessions of treatment, LPDL can provide a shorter and aesthetically better recovery time. long pulse-duration pulsed dye laser sebaceous hyperplasia short pulse-duration pulsed dye laser Dermatology Ying-Jui Chang verfasserin aut Ching-Chi Chi verfasserin aut Shu-Hui Wang verfasserin aut Tsung-Hua Tsai verfasserin aut In Dermatologica Sinica Wolters Kluwer Medknow Publications, 2017 35(2017), 3, Seite 119-123 (DE-627)627611729 (DE-600)2556793-7 2223330X nnns volume:35 year:2017 number:3 pages:119-123 https://doi.org/10.1016/j.dsi.2017.03.004 kostenfrei https://doaj.org/article/2bce41564f244bfe8e2790670be40ca8 kostenfrei http://www.sciencedirect.com/science/article/pii/S1027811716300805 kostenfrei https://doaj.org/toc/1027-8117 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_100 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2004 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 35 2017 3 119-123
spelling	10.1016/j.dsi.2017.03.004 doi (DE-627)DOAJ029099927 (DE-599)DOAJ2bce41564f244bfe8e2790670be40ca8 DE-627 ger DE-627 rakwb eng RL1-803 Sheng-Pei Wang verfasserin aut Using pulsed dye laser to treat sebaceous hyperplasia: comparison of short and long pulse-duration pulsed dye laser 2017 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background: Pulsed dye laser (PDL) is effective in treating sebaceous hyperplasia (SH). However, only short pulse-duration PDL (SPDL) has been used in previous studies. Objectives: To determine whether long pulse-duration PDL (LPDL) can achieve comparable efficacy in treating SH with fewer side effects versus SPDL. Methods: Eight patients with a total of 75 SH lesions were enrolled. Each SH lesion was randomized to be treated with two sessions of 595-nm SPDL with 0.45-millisecond pulse duration or 595-nm LPDL with 20-millisecond pulse duration. The second session was performed 4 weeks after the first session. Side effects including pain and post-treatment purpura were recorded. Follow-up examinations were conducted at 1 week and 4 weeks after the first session, and at 1 week, 4 weeks, and 8 weeks after the second session for repeated photography and assessing the diameter and thickness of each lesion, post-treatment purpura, and other adverse events. Results: All SH lesions responded to two sessions of PDL treatments. The reduction ratio of lesion diameter was 76.3% in the SPDL group and 70.0% in the LPDL group after two sessions of treatments (p = 0.644). The reduction ratio of lesion thickness was 79.6% in the SPDL group and 72.7% in the LPDL group after two sessions of treatment (p = 0.187). The mean intensity of pain was 3.13 on a 0–10-point scale for SPDL and 3.60 for LPDL (p = 0.660). The intensity of immediate post-treatment purpura was 4.13 on a 0–5-point scale for SPDL, and 1.80 for LPDL (p < 0.001). Some of the lesions treated by SPDL underwent an erosive stage. No scarring or discoloration was noted at 8 weeks after treatment. Conclusions: While SPDL and LPDL have comparable efficacy in treating SH after two sessions of treatment, LPDL can provide a shorter and aesthetically better recovery time. long pulse-duration pulsed dye laser sebaceous hyperplasia short pulse-duration pulsed dye laser Dermatology Ying-Jui Chang verfasserin aut Ching-Chi Chi verfasserin aut Shu-Hui Wang verfasserin aut Tsung-Hua Tsai verfasserin aut In Dermatologica Sinica Wolters Kluwer Medknow Publications, 2017 35(2017), 3, Seite 119-123 (DE-627)627611729 (DE-600)2556793-7 2223330X nnns volume:35 year:2017 number:3 pages:119-123 https://doi.org/10.1016/j.dsi.2017.03.004 kostenfrei https://doaj.org/article/2bce41564f244bfe8e2790670be40ca8 kostenfrei http://www.sciencedirect.com/science/article/pii/S1027811716300805 kostenfrei https://doaj.org/toc/1027-8117 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_100 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2004 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 35 2017 3 119-123
allfields_unstemmed	10.1016/j.dsi.2017.03.004 doi (DE-627)DOAJ029099927 (DE-599)DOAJ2bce41564f244bfe8e2790670be40ca8 DE-627 ger DE-627 rakwb eng RL1-803 Sheng-Pei Wang verfasserin aut Using pulsed dye laser to treat sebaceous hyperplasia: comparison of short and long pulse-duration pulsed dye laser 2017 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background: Pulsed dye laser (PDL) is effective in treating sebaceous hyperplasia (SH). However, only short pulse-duration PDL (SPDL) has been used in previous studies. Objectives: To determine whether long pulse-duration PDL (LPDL) can achieve comparable efficacy in treating SH with fewer side effects versus SPDL. Methods: Eight patients with a total of 75 SH lesions were enrolled. Each SH lesion was randomized to be treated with two sessions of 595-nm SPDL with 0.45-millisecond pulse duration or 595-nm LPDL with 20-millisecond pulse duration. The second session was performed 4 weeks after the first session. Side effects including pain and post-treatment purpura were recorded. Follow-up examinations were conducted at 1 week and 4 weeks after the first session, and at 1 week, 4 weeks, and 8 weeks after the second session for repeated photography and assessing the diameter and thickness of each lesion, post-treatment purpura, and other adverse events. Results: All SH lesions responded to two sessions of PDL treatments. The reduction ratio of lesion diameter was 76.3% in the SPDL group and 70.0% in the LPDL group after two sessions of treatments (p = 0.644). The reduction ratio of lesion thickness was 79.6% in the SPDL group and 72.7% in the LPDL group after two sessions of treatment (p = 0.187). The mean intensity of pain was 3.13 on a 0–10-point scale for SPDL and 3.60 for LPDL (p = 0.660). The intensity of immediate post-treatment purpura was 4.13 on a 0–5-point scale for SPDL, and 1.80 for LPDL (p < 0.001). Some of the lesions treated by SPDL underwent an erosive stage. No scarring or discoloration was noted at 8 weeks after treatment. Conclusions: While SPDL and LPDL have comparable efficacy in treating SH after two sessions of treatment, LPDL can provide a shorter and aesthetically better recovery time. long pulse-duration pulsed dye laser sebaceous hyperplasia short pulse-duration pulsed dye laser Dermatology Ying-Jui Chang verfasserin aut Ching-Chi Chi verfasserin aut Shu-Hui Wang verfasserin aut Tsung-Hua Tsai verfasserin aut In Dermatologica Sinica Wolters Kluwer Medknow Publications, 2017 35(2017), 3, Seite 119-123 (DE-627)627611729 (DE-600)2556793-7 2223330X nnns volume:35 year:2017 number:3 pages:119-123 https://doi.org/10.1016/j.dsi.2017.03.004 kostenfrei https://doaj.org/article/2bce41564f244bfe8e2790670be40ca8 kostenfrei http://www.sciencedirect.com/science/article/pii/S1027811716300805 kostenfrei https://doaj.org/toc/1027-8117 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_100 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2004 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 35 2017 3 119-123
allfieldsGer	10.1016/j.dsi.2017.03.004 doi (DE-627)DOAJ029099927 (DE-599)DOAJ2bce41564f244bfe8e2790670be40ca8 DE-627 ger DE-627 rakwb eng RL1-803 Sheng-Pei Wang verfasserin aut Using pulsed dye laser to treat sebaceous hyperplasia: comparison of short and long pulse-duration pulsed dye laser 2017 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background: Pulsed dye laser (PDL) is effective in treating sebaceous hyperplasia (SH). However, only short pulse-duration PDL (SPDL) has been used in previous studies. Objectives: To determine whether long pulse-duration PDL (LPDL) can achieve comparable efficacy in treating SH with fewer side effects versus SPDL. Methods: Eight patients with a total of 75 SH lesions were enrolled. Each SH lesion was randomized to be treated with two sessions of 595-nm SPDL with 0.45-millisecond pulse duration or 595-nm LPDL with 20-millisecond pulse duration. The second session was performed 4 weeks after the first session. Side effects including pain and post-treatment purpura were recorded. Follow-up examinations were conducted at 1 week and 4 weeks after the first session, and at 1 week, 4 weeks, and 8 weeks after the second session for repeated photography and assessing the diameter and thickness of each lesion, post-treatment purpura, and other adverse events. Results: All SH lesions responded to two sessions of PDL treatments. The reduction ratio of lesion diameter was 76.3% in the SPDL group and 70.0% in the LPDL group after two sessions of treatments (p = 0.644). The reduction ratio of lesion thickness was 79.6% in the SPDL group and 72.7% in the LPDL group after two sessions of treatment (p = 0.187). The mean intensity of pain was 3.13 on a 0–10-point scale for SPDL and 3.60 for LPDL (p = 0.660). The intensity of immediate post-treatment purpura was 4.13 on a 0–5-point scale for SPDL, and 1.80 for LPDL (p < 0.001). Some of the lesions treated by SPDL underwent an erosive stage. No scarring or discoloration was noted at 8 weeks after treatment. Conclusions: While SPDL and LPDL have comparable efficacy in treating SH after two sessions of treatment, LPDL can provide a shorter and aesthetically better recovery time. long pulse-duration pulsed dye laser sebaceous hyperplasia short pulse-duration pulsed dye laser Dermatology Ying-Jui Chang verfasserin aut Ching-Chi Chi verfasserin aut Shu-Hui Wang verfasserin aut Tsung-Hua Tsai verfasserin aut In Dermatologica Sinica Wolters Kluwer Medknow Publications, 2017 35(2017), 3, Seite 119-123 (DE-627)627611729 (DE-600)2556793-7 2223330X nnns volume:35 year:2017 number:3 pages:119-123 https://doi.org/10.1016/j.dsi.2017.03.004 kostenfrei https://doaj.org/article/2bce41564f244bfe8e2790670be40ca8 kostenfrei http://www.sciencedirect.com/science/article/pii/S1027811716300805 kostenfrei https://doaj.org/toc/1027-8117 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_100 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2004 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 35 2017 3 119-123
allfieldsSound	10.1016/j.dsi.2017.03.004 doi (DE-627)DOAJ029099927 (DE-599)DOAJ2bce41564f244bfe8e2790670be40ca8 DE-627 ger DE-627 rakwb eng RL1-803 Sheng-Pei Wang verfasserin aut Using pulsed dye laser to treat sebaceous hyperplasia: comparison of short and long pulse-duration pulsed dye laser 2017 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Background: Pulsed dye laser (PDL) is effective in treating sebaceous hyperplasia (SH). However, only short pulse-duration PDL (SPDL) has been used in previous studies. Objectives: To determine whether long pulse-duration PDL (LPDL) can achieve comparable efficacy in treating SH with fewer side effects versus SPDL. Methods: Eight patients with a total of 75 SH lesions were enrolled. Each SH lesion was randomized to be treated with two sessions of 595-nm SPDL with 0.45-millisecond pulse duration or 595-nm LPDL with 20-millisecond pulse duration. The second session was performed 4 weeks after the first session. Side effects including pain and post-treatment purpura were recorded. Follow-up examinations were conducted at 1 week and 4 weeks after the first session, and at 1 week, 4 weeks, and 8 weeks after the second session for repeated photography and assessing the diameter and thickness of each lesion, post-treatment purpura, and other adverse events. Results: All SH lesions responded to two sessions of PDL treatments. The reduction ratio of lesion diameter was 76.3% in the SPDL group and 70.0% in the LPDL group after two sessions of treatments (p = 0.644). The reduction ratio of lesion thickness was 79.6% in the SPDL group and 72.7% in the LPDL group after two sessions of treatment (p = 0.187). The mean intensity of pain was 3.13 on a 0–10-point scale for SPDL and 3.60 for LPDL (p = 0.660). The intensity of immediate post-treatment purpura was 4.13 on a 0–5-point scale for SPDL, and 1.80 for LPDL (p < 0.001). Some of the lesions treated by SPDL underwent an erosive stage. No scarring or discoloration was noted at 8 weeks after treatment. Conclusions: While SPDL and LPDL have comparable efficacy in treating SH after two sessions of treatment, LPDL can provide a shorter and aesthetically better recovery time. long pulse-duration pulsed dye laser sebaceous hyperplasia short pulse-duration pulsed dye laser Dermatology Ying-Jui Chang verfasserin aut Ching-Chi Chi verfasserin aut Shu-Hui Wang verfasserin aut Tsung-Hua Tsai verfasserin aut In Dermatologica Sinica Wolters Kluwer Medknow Publications, 2017 35(2017), 3, Seite 119-123 (DE-627)627611729 (DE-600)2556793-7 2223330X nnns volume:35 year:2017 number:3 pages:119-123 https://doi.org/10.1016/j.dsi.2017.03.004 kostenfrei https://doaj.org/article/2bce41564f244bfe8e2790670be40ca8 kostenfrei http://www.sciencedirect.com/science/article/pii/S1027811716300805 kostenfrei https://doaj.org/toc/1027-8117 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_100 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2004 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 35 2017 3 119-123
language	English
source	In Dermatologica Sinica 35(2017), 3, Seite 119-123 volume:35 year:2017 number:3 pages:119-123
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topic_facet	long pulse-duration pulsed dye laser sebaceous hyperplasia short pulse-duration pulsed dye laser Dermatology
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author	Sheng-Pei Wang
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topic	misc RL1-803 misc long pulse-duration pulsed dye laser misc sebaceous hyperplasia misc short pulse-duration pulsed dye laser misc Dermatology
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title	Using pulsed dye laser to treat sebaceous hyperplasia: comparison of short and long pulse-duration pulsed dye laser
ctrlnum	(DE-627)DOAJ029099927 (DE-599)DOAJ2bce41564f244bfe8e2790670be40ca8
title_full	Using pulsed dye laser to treat sebaceous hyperplasia: comparison of short and long pulse-duration pulsed dye laser
author_sort	Sheng-Pei Wang
journal	Dermatologica Sinica
journalStr	Dermatologica Sinica
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lang_code	eng
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author_browse	Sheng-Pei Wang Ying-Jui Chang Ching-Chi Chi Shu-Hui Wang Tsung-Hua Tsai
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format_se	Elektronische Aufsätze
author-letter	Sheng-Pei Wang
doi_str_mv	10.1016/j.dsi.2017.03.004
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title_sort	using pulsed dye laser to treat sebaceous hyperplasia: comparison of short and long pulse-duration pulsed dye laser
callnumber	RL1-803
title_auth	Using pulsed dye laser to treat sebaceous hyperplasia: comparison of short and long pulse-duration pulsed dye laser
abstract	Background: Pulsed dye laser (PDL) is effective in treating sebaceous hyperplasia (SH). However, only short pulse-duration PDL (SPDL) has been used in previous studies. Objectives: To determine whether long pulse-duration PDL (LPDL) can achieve comparable efficacy in treating SH with fewer side effects versus SPDL. Methods: Eight patients with a total of 75 SH lesions were enrolled. Each SH lesion was randomized to be treated with two sessions of 595-nm SPDL with 0.45-millisecond pulse duration or 595-nm LPDL with 20-millisecond pulse duration. The second session was performed 4 weeks after the first session. Side effects including pain and post-treatment purpura were recorded. Follow-up examinations were conducted at 1 week and 4 weeks after the first session, and at 1 week, 4 weeks, and 8 weeks after the second session for repeated photography and assessing the diameter and thickness of each lesion, post-treatment purpura, and other adverse events. Results: All SH lesions responded to two sessions of PDL treatments. The reduction ratio of lesion diameter was 76.3% in the SPDL group and 70.0% in the LPDL group after two sessions of treatments (p = 0.644). The reduction ratio of lesion thickness was 79.6% in the SPDL group and 72.7% in the LPDL group after two sessions of treatment (p = 0.187). The mean intensity of pain was 3.13 on a 0–10-point scale for SPDL and 3.60 for LPDL (p = 0.660). The intensity of immediate post-treatment purpura was 4.13 on a 0–5-point scale for SPDL, and 1.80 for LPDL (p < 0.001). Some of the lesions treated by SPDL underwent an erosive stage. No scarring or discoloration was noted at 8 weeks after treatment. Conclusions: While SPDL and LPDL have comparable efficacy in treating SH after two sessions of treatment, LPDL can provide a shorter and aesthetically better recovery time.
abstractGer	Background: Pulsed dye laser (PDL) is effective in treating sebaceous hyperplasia (SH). However, only short pulse-duration PDL (SPDL) has been used in previous studies. Objectives: To determine whether long pulse-duration PDL (LPDL) can achieve comparable efficacy in treating SH with fewer side effects versus SPDL. Methods: Eight patients with a total of 75 SH lesions were enrolled. Each SH lesion was randomized to be treated with two sessions of 595-nm SPDL with 0.45-millisecond pulse duration or 595-nm LPDL with 20-millisecond pulse duration. The second session was performed 4 weeks after the first session. Side effects including pain and post-treatment purpura were recorded. Follow-up examinations were conducted at 1 week and 4 weeks after the first session, and at 1 week, 4 weeks, and 8 weeks after the second session for repeated photography and assessing the diameter and thickness of each lesion, post-treatment purpura, and other adverse events. Results: All SH lesions responded to two sessions of PDL treatments. The reduction ratio of lesion diameter was 76.3% in the SPDL group and 70.0% in the LPDL group after two sessions of treatments (p = 0.644). The reduction ratio of lesion thickness was 79.6% in the SPDL group and 72.7% in the LPDL group after two sessions of treatment (p = 0.187). The mean intensity of pain was 3.13 on a 0–10-point scale for SPDL and 3.60 for LPDL (p = 0.660). The intensity of immediate post-treatment purpura was 4.13 on a 0–5-point scale for SPDL, and 1.80 for LPDL (p < 0.001). Some of the lesions treated by SPDL underwent an erosive stage. No scarring or discoloration was noted at 8 weeks after treatment. Conclusions: While SPDL and LPDL have comparable efficacy in treating SH after two sessions of treatment, LPDL can provide a shorter and aesthetically better recovery time.
abstract_unstemmed	Background: Pulsed dye laser (PDL) is effective in treating sebaceous hyperplasia (SH). However, only short pulse-duration PDL (SPDL) has been used in previous studies. Objectives: To determine whether long pulse-duration PDL (LPDL) can achieve comparable efficacy in treating SH with fewer side effects versus SPDL. Methods: Eight patients with a total of 75 SH lesions were enrolled. Each SH lesion was randomized to be treated with two sessions of 595-nm SPDL with 0.45-millisecond pulse duration or 595-nm LPDL with 20-millisecond pulse duration. The second session was performed 4 weeks after the first session. Side effects including pain and post-treatment purpura were recorded. Follow-up examinations were conducted at 1 week and 4 weeks after the first session, and at 1 week, 4 weeks, and 8 weeks after the second session for repeated photography and assessing the diameter and thickness of each lesion, post-treatment purpura, and other adverse events. Results: All SH lesions responded to two sessions of PDL treatments. The reduction ratio of lesion diameter was 76.3% in the SPDL group and 70.0% in the LPDL group after two sessions of treatments (p = 0.644). The reduction ratio of lesion thickness was 79.6% in the SPDL group and 72.7% in the LPDL group after two sessions of treatment (p = 0.187). The mean intensity of pain was 3.13 on a 0–10-point scale for SPDL and 3.60 for LPDL (p = 0.660). The intensity of immediate post-treatment purpura was 4.13 on a 0–5-point scale for SPDL, and 1.80 for LPDL (p < 0.001). Some of the lesions treated by SPDL underwent an erosive stage. No scarring or discoloration was noted at 8 weeks after treatment. Conclusions: While SPDL and LPDL have comparable efficacy in treating SH after two sessions of treatment, LPDL can provide a shorter and aesthetically better recovery time.
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title_short	Using pulsed dye laser to treat sebaceous hyperplasia: comparison of short and long pulse-duration pulsed dye laser
url	https://doi.org/10.1016/j.dsi.2017.03.004 https://doaj.org/article/2bce41564f244bfe8e2790670be40ca8 http://www.sciencedirect.com/science/article/pii/S1027811716300805 https://doaj.org/toc/1027-8117
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up_date	2024-07-03T21:09:08.037Z
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