The frequency of detection of markers of Сytomegalovirus infection in children with recurrent respiratory diseases in patients with Shiga-toxin-associated hemolytic-uremic syndrome (STEC-HUS)

The paper presents data on the detection and role of cytomegalovirus infection (CMVI) in 146 children of certain groups aged from 3 months to 15 years who were hospitalized — frequently ill children with respiratory pathology, patients with shiga-toxin-associated hemolytic uremic syndrome (STEC-HUS)...
Ausführliche Beschreibung

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Autor*in:	I. B. Repina [verfasserIn] L. V. Feklisova [verfasserIn] M. K. Khadisova [verfasserIn] N. V. Karazhas [verfasserIn] E. I. Likhanskaya [verfasserIn]

Format:	E-Artikel
Sprache:	Russisch

Erschienen:	2021

Schlagwörter:	дети цитомегаловирусная инфекция реккурентные респираторные заболевания шига-токсин-ассоциированный гемолитико-уремический синдром (stec-hus)

Übergeordnetes Werk:	In: Детские инфекции (Москва) - LLC "Diagnostics and Vaccines", 2016, 20(2021), 1, Seite 12-18
Übergeordnetes Werk:	volume:20 ; year:2021 ; number:1 ; pages:12-18

Links:	Link aufrufen Link aufrufen Link aufrufen Journal toc

DOI / URN:	10.22627/2072-8107-2021-20-1-12-18

Katalog-ID:	DOAJ029552389

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245	1	4	\|a The frequency of detection of markers of Сytomegalovirus infection in children with recurrent respiratory diseases in patients with Shiga-toxin-associated hemolytic-uremic syndrome (STEC-HUS)
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520			\|a The paper presents data on the detection and role of cytomegalovirus infection (CMVI) in 146 children of certain groups aged from 3 months to 15 years who were hospitalized — frequently ill children with respiratory pathology, patients with shiga-toxin-associated hemolytic uremic syndrome (STEC-HUS) and schoolchildren with somatic diseases during rehabilitation in a sanatorium.The aim of the study was to determine the frequency of detection of CMVI in the presented groups, the originality of the main clinical manifestations in correlation with the markers of activity of herpesvirus type V infection. Clinical monitoring was carried out, oropharyngeal swabs, saliva,blood samples (serum and blood cells) were studied using a set of laboratory diagnostic methods:RCM (rapid culture method) on Vero- and M-19 cells, IIR (reaction of indirect immunofluorescence), ELISA to detect specific antigens and antibodies (IgM, IgG).The detection rate of CMV IgG in diagnostic values ranged from 6.4% in the group of frequently ill children with respiratory pathology to 31.7% in schoolchildren of the sanatorium, the acute course of infection was detected in3.2% and 6.4%, respectively, based on markers of acute infection (CMV IgM and cytomegalovirus antigen). In patients with STEC-HUS CMV IgG in diagnostic titers were recorded with the highest frequency — in 74.4% of patients.
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650		4	\|a шига-токсин-ассоциированный гемолитико-уремический синдром (stec-hus)
653		0	\|a Pediatrics
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700	0		\|a M. K. Khadisova \|e verfasserin \|4 aut
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700	0		\|a E. I. Likhanskaya \|e verfasserin \|4 aut
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allfields	10.22627/2072-8107-2021-20-1-12-18 doi (DE-627)DOAJ029552389 (DE-599)DOAJ08d160f841fa4837a9612d8d32add169 DE-627 ger DE-627 rakwb rus RJ1-570 I. B. Repina verfasserin aut The frequency of detection of markers of Сytomegalovirus infection in children with recurrent respiratory diseases in patients with Shiga-toxin-associated hemolytic-uremic syndrome (STEC-HUS) 2021 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier The paper presents data on the detection and role of cytomegalovirus infection (CMVI) in 146 children of certain groups aged from 3 months to 15 years who were hospitalized — frequently ill children with respiratory pathology, patients with shiga-toxin-associated hemolytic uremic syndrome (STEC-HUS) and schoolchildren with somatic diseases during rehabilitation in a sanatorium.The aim of the study was to determine the frequency of detection of CMVI in the presented groups, the originality of the main clinical manifestations in correlation with the markers of activity of herpesvirus type V infection. Clinical monitoring was carried out, oropharyngeal swabs, saliva,blood samples (serum and blood cells) were studied using a set of laboratory diagnostic methods:RCM (rapid culture method) on Vero- and M-19 cells, IIR (reaction of indirect immunofluorescence), ELISA to detect specific antigens and antibodies (IgM, IgG).The detection rate of CMV IgG in diagnostic values ranged from 6.4% in the group of frequently ill children with respiratory pathology to 31.7% in schoolchildren of the sanatorium, the acute course of infection was detected in3.2% and 6.4%, respectively, based on markers of acute infection (CMV IgM and cytomegalovirus antigen). In patients with STEC-HUS CMV IgG in diagnostic titers were recorded with the highest frequency — in 74.4% of patients. дети цитомегаловирусная инфекция реккурентные респираторные заболевания шига-токсин-ассоциированный гемолитико-уремический синдром (stec-hus) Pediatrics L. V. Feklisova verfasserin aut M. K. Khadisova verfasserin aut N. V. Karazhas verfasserin aut E. I. Likhanskaya verfasserin aut In Детские инфекции (Москва) LLC "Diagnostics and Vaccines", 2016 20(2021), 1, Seite 12-18 (DE-627)1760619124 20728107 nnns volume:20 year:2021 number:1 pages:12-18 https://doi.org/10.22627/2072-8107-2021-20-1-12-18 kostenfrei https://doaj.org/article/08d160f841fa4837a9612d8d32add169 kostenfrei https://detinf.elpub.ru/jour/article/view/565 kostenfrei https://doaj.org/toc/2072-8107 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 20 2021 1 12-18
spelling	10.22627/2072-8107-2021-20-1-12-18 doi (DE-627)DOAJ029552389 (DE-599)DOAJ08d160f841fa4837a9612d8d32add169 DE-627 ger DE-627 rakwb rus RJ1-570 I. B. Repina verfasserin aut The frequency of detection of markers of Сytomegalovirus infection in children with recurrent respiratory diseases in patients with Shiga-toxin-associated hemolytic-uremic syndrome (STEC-HUS) 2021 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier The paper presents data on the detection and role of cytomegalovirus infection (CMVI) in 146 children of certain groups aged from 3 months to 15 years who were hospitalized — frequently ill children with respiratory pathology, patients with shiga-toxin-associated hemolytic uremic syndrome (STEC-HUS) and schoolchildren with somatic diseases during rehabilitation in a sanatorium.The aim of the study was to determine the frequency of detection of CMVI in the presented groups, the originality of the main clinical manifestations in correlation with the markers of activity of herpesvirus type V infection. Clinical monitoring was carried out, oropharyngeal swabs, saliva,blood samples (serum and blood cells) were studied using a set of laboratory diagnostic methods:RCM (rapid culture method) on Vero- and M-19 cells, IIR (reaction of indirect immunofluorescence), ELISA to detect specific antigens and antibodies (IgM, IgG).The detection rate of CMV IgG in diagnostic values ranged from 6.4% in the group of frequently ill children with respiratory pathology to 31.7% in schoolchildren of the sanatorium, the acute course of infection was detected in3.2% and 6.4%, respectively, based on markers of acute infection (CMV IgM and cytomegalovirus antigen). In patients with STEC-HUS CMV IgG in diagnostic titers were recorded with the highest frequency — in 74.4% of patients. дети цитомегаловирусная инфекция реккурентные респираторные заболевания шига-токсин-ассоциированный гемолитико-уремический синдром (stec-hus) Pediatrics L. V. Feklisova verfasserin aut M. K. Khadisova verfasserin aut N. V. Karazhas verfasserin aut E. I. Likhanskaya verfasserin aut In Детские инфекции (Москва) LLC "Diagnostics and Vaccines", 2016 20(2021), 1, Seite 12-18 (DE-627)1760619124 20728107 nnns volume:20 year:2021 number:1 pages:12-18 https://doi.org/10.22627/2072-8107-2021-20-1-12-18 kostenfrei https://doaj.org/article/08d160f841fa4837a9612d8d32add169 kostenfrei https://detinf.elpub.ru/jour/article/view/565 kostenfrei https://doaj.org/toc/2072-8107 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 20 2021 1 12-18
allfields_unstemmed	10.22627/2072-8107-2021-20-1-12-18 doi (DE-627)DOAJ029552389 (DE-599)DOAJ08d160f841fa4837a9612d8d32add169 DE-627 ger DE-627 rakwb rus RJ1-570 I. B. Repina verfasserin aut The frequency of detection of markers of Сytomegalovirus infection in children with recurrent respiratory diseases in patients with Shiga-toxin-associated hemolytic-uremic syndrome (STEC-HUS) 2021 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier The paper presents data on the detection and role of cytomegalovirus infection (CMVI) in 146 children of certain groups aged from 3 months to 15 years who were hospitalized — frequently ill children with respiratory pathology, patients with shiga-toxin-associated hemolytic uremic syndrome (STEC-HUS) and schoolchildren with somatic diseases during rehabilitation in a sanatorium.The aim of the study was to determine the frequency of detection of CMVI in the presented groups, the originality of the main clinical manifestations in correlation with the markers of activity of herpesvirus type V infection. Clinical monitoring was carried out, oropharyngeal swabs, saliva,blood samples (serum and blood cells) were studied using a set of laboratory diagnostic methods:RCM (rapid culture method) on Vero- and M-19 cells, IIR (reaction of indirect immunofluorescence), ELISA to detect specific antigens and antibodies (IgM, IgG).The detection rate of CMV IgG in diagnostic values ranged from 6.4% in the group of frequently ill children with respiratory pathology to 31.7% in schoolchildren of the sanatorium, the acute course of infection was detected in3.2% and 6.4%, respectively, based on markers of acute infection (CMV IgM and cytomegalovirus antigen). In patients with STEC-HUS CMV IgG in diagnostic titers were recorded with the highest frequency — in 74.4% of patients. дети цитомегаловирусная инфекция реккурентные респираторные заболевания шига-токсин-ассоциированный гемолитико-уремический синдром (stec-hus) Pediatrics L. V. Feklisova verfasserin aut M. K. Khadisova verfasserin aut N. V. Karazhas verfasserin aut E. I. Likhanskaya verfasserin aut In Детские инфекции (Москва) LLC "Diagnostics and Vaccines", 2016 20(2021), 1, Seite 12-18 (DE-627)1760619124 20728107 nnns volume:20 year:2021 number:1 pages:12-18 https://doi.org/10.22627/2072-8107-2021-20-1-12-18 kostenfrei https://doaj.org/article/08d160f841fa4837a9612d8d32add169 kostenfrei https://detinf.elpub.ru/jour/article/view/565 kostenfrei https://doaj.org/toc/2072-8107 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 20 2021 1 12-18
allfieldsGer	10.22627/2072-8107-2021-20-1-12-18 doi (DE-627)DOAJ029552389 (DE-599)DOAJ08d160f841fa4837a9612d8d32add169 DE-627 ger DE-627 rakwb rus RJ1-570 I. B. Repina verfasserin aut The frequency of detection of markers of Сytomegalovirus infection in children with recurrent respiratory diseases in patients with Shiga-toxin-associated hemolytic-uremic syndrome (STEC-HUS) 2021 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier The paper presents data on the detection and role of cytomegalovirus infection (CMVI) in 146 children of certain groups aged from 3 months to 15 years who were hospitalized — frequently ill children with respiratory pathology, patients with shiga-toxin-associated hemolytic uremic syndrome (STEC-HUS) and schoolchildren with somatic diseases during rehabilitation in a sanatorium.The aim of the study was to determine the frequency of detection of CMVI in the presented groups, the originality of the main clinical manifestations in correlation with the markers of activity of herpesvirus type V infection. Clinical monitoring was carried out, oropharyngeal swabs, saliva,blood samples (serum and blood cells) were studied using a set of laboratory diagnostic methods:RCM (rapid culture method) on Vero- and M-19 cells, IIR (reaction of indirect immunofluorescence), ELISA to detect specific antigens and antibodies (IgM, IgG).The detection rate of CMV IgG in diagnostic values ranged from 6.4% in the group of frequently ill children with respiratory pathology to 31.7% in schoolchildren of the sanatorium, the acute course of infection was detected in3.2% and 6.4%, respectively, based on markers of acute infection (CMV IgM and cytomegalovirus antigen). In patients with STEC-HUS CMV IgG in diagnostic titers were recorded with the highest frequency — in 74.4% of patients. дети цитомегаловирусная инфекция реккурентные респираторные заболевания шига-токсин-ассоциированный гемолитико-уремический синдром (stec-hus) Pediatrics L. V. Feklisova verfasserin aut M. K. Khadisova verfasserin aut N. V. Karazhas verfasserin aut E. I. Likhanskaya verfasserin aut In Детские инфекции (Москва) LLC "Diagnostics and Vaccines", 2016 20(2021), 1, Seite 12-18 (DE-627)1760619124 20728107 nnns volume:20 year:2021 number:1 pages:12-18 https://doi.org/10.22627/2072-8107-2021-20-1-12-18 kostenfrei https://doaj.org/article/08d160f841fa4837a9612d8d32add169 kostenfrei https://detinf.elpub.ru/jour/article/view/565 kostenfrei https://doaj.org/toc/2072-8107 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 20 2021 1 12-18
allfieldsSound	10.22627/2072-8107-2021-20-1-12-18 doi (DE-627)DOAJ029552389 (DE-599)DOAJ08d160f841fa4837a9612d8d32add169 DE-627 ger DE-627 rakwb rus RJ1-570 I. B. Repina verfasserin aut The frequency of detection of markers of Сytomegalovirus infection in children with recurrent respiratory diseases in patients with Shiga-toxin-associated hemolytic-uremic syndrome (STEC-HUS) 2021 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier The paper presents data on the detection and role of cytomegalovirus infection (CMVI) in 146 children of certain groups aged from 3 months to 15 years who were hospitalized — frequently ill children with respiratory pathology, patients with shiga-toxin-associated hemolytic uremic syndrome (STEC-HUS) and schoolchildren with somatic diseases during rehabilitation in a sanatorium.The aim of the study was to determine the frequency of detection of CMVI in the presented groups, the originality of the main clinical manifestations in correlation with the markers of activity of herpesvirus type V infection. Clinical monitoring was carried out, oropharyngeal swabs, saliva,blood samples (serum and blood cells) were studied using a set of laboratory diagnostic methods:RCM (rapid culture method) on Vero- and M-19 cells, IIR (reaction of indirect immunofluorescence), ELISA to detect specific antigens and antibodies (IgM, IgG).The detection rate of CMV IgG in diagnostic values ranged from 6.4% in the group of frequently ill children with respiratory pathology to 31.7% in schoolchildren of the sanatorium, the acute course of infection was detected in3.2% and 6.4%, respectively, based on markers of acute infection (CMV IgM and cytomegalovirus antigen). In patients with STEC-HUS CMV IgG in diagnostic titers were recorded with the highest frequency — in 74.4% of patients. дети цитомегаловирусная инфекция реккурентные респираторные заболевания шига-токсин-ассоциированный гемолитико-уремический синдром (stec-hus) Pediatrics L. V. Feklisova verfasserin aut M. K. Khadisova verfasserin aut N. V. Karazhas verfasserin aut E. I. Likhanskaya verfasserin aut In Детские инфекции (Москва) LLC "Diagnostics and Vaccines", 2016 20(2021), 1, Seite 12-18 (DE-627)1760619124 20728107 nnns volume:20 year:2021 number:1 pages:12-18 https://doi.org/10.22627/2072-8107-2021-20-1-12-18 kostenfrei https://doaj.org/article/08d160f841fa4837a9612d8d32add169 kostenfrei https://detinf.elpub.ru/jour/article/view/565 kostenfrei https://doaj.org/toc/2072-8107 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 20 2021 1 12-18
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callnumber-first	R - Medicine
author	I. B. Repina
spellingShingle	I. B. Repina misc RJ1-570 misc дети misc цитомегаловирусная инфекция misc реккурентные респираторные заболевания misc шига-токсин-ассоциированный гемолитико-уремический синдром (stec-hus) misc Pediatrics The frequency of detection of markers of Сytomegalovirus infection in children with recurrent respiratory diseases in patients with Shiga-toxin-associated hemolytic-uremic syndrome (STEC-HUS)
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topic_title	RJ1-570 The frequency of detection of markers of Сytomegalovirus infection in children with recurrent respiratory diseases in patients with Shiga-toxin-associated hemolytic-uremic syndrome (STEC-HUS) дети цитомегаловирусная инфекция реккурентные респираторные заболевания шига-токсин-ассоциированный гемолитико-уремический синдром (stec-hus)
topic	misc RJ1-570 misc дети misc цитомегаловирусная инфекция misc реккурентные респираторные заболевания misc шига-токсин-ассоциированный гемолитико-уремический синдром (stec-hus) misc Pediatrics
topic_unstemmed	misc RJ1-570 misc дети misc цитомегаловирусная инфекция misc реккурентные респираторные заболевания misc шига-токсин-ассоциированный гемолитико-уремический синдром (stec-hus) misc Pediatrics
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title	The frequency of detection of markers of Сytomegalovirus infection in children with recurrent respiratory diseases in patients with Shiga-toxin-associated hemolytic-uremic syndrome (STEC-HUS)
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title_full	The frequency of detection of markers of Сytomegalovirus infection in children with recurrent respiratory diseases in patients with Shiga-toxin-associated hemolytic-uremic syndrome (STEC-HUS)
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author_browse	I. B. Repina L. V. Feklisova M. K. Khadisova N. V. Karazhas E. I. Likhanskaya
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title_sort	frequency of detection of markers of сytomegalovirus infection in children with recurrent respiratory diseases in patients with shiga-toxin-associated hemolytic-uremic syndrome (stec-hus)
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title_auth	The frequency of detection of markers of Сytomegalovirus infection in children with recurrent respiratory diseases in patients with Shiga-toxin-associated hemolytic-uremic syndrome (STEC-HUS)
abstract	The paper presents data on the detection and role of cytomegalovirus infection (CMVI) in 146 children of certain groups aged from 3 months to 15 years who were hospitalized — frequently ill children with respiratory pathology, patients with shiga-toxin-associated hemolytic uremic syndrome (STEC-HUS) and schoolchildren with somatic diseases during rehabilitation in a sanatorium.The aim of the study was to determine the frequency of detection of CMVI in the presented groups, the originality of the main clinical manifestations in correlation with the markers of activity of herpesvirus type V infection. Clinical monitoring was carried out, oropharyngeal swabs, saliva,blood samples (serum and blood cells) were studied using a set of laboratory diagnostic methods:RCM (rapid culture method) on Vero- and M-19 cells, IIR (reaction of indirect immunofluorescence), ELISA to detect specific antigens and antibodies (IgM, IgG).The detection rate of CMV IgG in diagnostic values ranged from 6.4% in the group of frequently ill children with respiratory pathology to 31.7% in schoolchildren of the sanatorium, the acute course of infection was detected in3.2% and 6.4%, respectively, based on markers of acute infection (CMV IgM and cytomegalovirus antigen). In patients with STEC-HUS CMV IgG in diagnostic titers were recorded with the highest frequency — in 74.4% of patients.
abstractGer	The paper presents data on the detection and role of cytomegalovirus infection (CMVI) in 146 children of certain groups aged from 3 months to 15 years who were hospitalized — frequently ill children with respiratory pathology, patients with shiga-toxin-associated hemolytic uremic syndrome (STEC-HUS) and schoolchildren with somatic diseases during rehabilitation in a sanatorium.The aim of the study was to determine the frequency of detection of CMVI in the presented groups, the originality of the main clinical manifestations in correlation with the markers of activity of herpesvirus type V infection. Clinical monitoring was carried out, oropharyngeal swabs, saliva,blood samples (serum and blood cells) were studied using a set of laboratory diagnostic methods:RCM (rapid culture method) on Vero- and M-19 cells, IIR (reaction of indirect immunofluorescence), ELISA to detect specific antigens and antibodies (IgM, IgG).The detection rate of CMV IgG in diagnostic values ranged from 6.4% in the group of frequently ill children with respiratory pathology to 31.7% in schoolchildren of the sanatorium, the acute course of infection was detected in3.2% and 6.4%, respectively, based on markers of acute infection (CMV IgM and cytomegalovirus antigen). In patients with STEC-HUS CMV IgG in diagnostic titers were recorded with the highest frequency — in 74.4% of patients.
abstract_unstemmed	The paper presents data on the detection and role of cytomegalovirus infection (CMVI) in 146 children of certain groups aged from 3 months to 15 years who were hospitalized — frequently ill children with respiratory pathology, patients with shiga-toxin-associated hemolytic uremic syndrome (STEC-HUS) and schoolchildren with somatic diseases during rehabilitation in a sanatorium.The aim of the study was to determine the frequency of detection of CMVI in the presented groups, the originality of the main clinical manifestations in correlation with the markers of activity of herpesvirus type V infection. Clinical monitoring was carried out, oropharyngeal swabs, saliva,blood samples (serum and blood cells) were studied using a set of laboratory diagnostic methods:RCM (rapid culture method) on Vero- and M-19 cells, IIR (reaction of indirect immunofluorescence), ELISA to detect specific antigens and antibodies (IgM, IgG).The detection rate of CMV IgG in diagnostic values ranged from 6.4% in the group of frequently ill children with respiratory pathology to 31.7% in schoolchildren of the sanatorium, the acute course of infection was detected in3.2% and 6.4%, respectively, based on markers of acute infection (CMV IgM and cytomegalovirus antigen). In patients with STEC-HUS CMV IgG in diagnostic titers were recorded with the highest frequency — in 74.4% of patients.
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title_short	The frequency of detection of markers of Сytomegalovirus infection in children with recurrent respiratory diseases in patients with Shiga-toxin-associated hemolytic-uremic syndrome (STEC-HUS)
url	https://doi.org/10.22627/2072-8107-2021-20-1-12-18 https://doaj.org/article/08d160f841fa4837a9612d8d32add169 https://detinf.elpub.ru/jour/article/view/565 https://doaj.org/toc/2072-8107
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The frequency of detection of markers of Сytomegalovirus infection in children with recurrent respiratory diseases in patients with Shiga-toxin-associated hemolytic-uremic syndrome (STEC-HUS)

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