National Antibiotic Consumption for Human Use in Sierra Leone (2017–2019): A Cross-Sectional Study
Monitoring antibiotic consumption is crucial to tackling antimicrobial resistance. However, currently there is no system in Sierra Leone for recording and reporting on antibiotic consumption. We therefore conducted a cross-sectional study to assess national antibiotic consumption expressed as define...
Ausführliche Beschreibung
Autor*in: |
Joseph Sam Kanu [verfasserIn] Mohammed Khogali [verfasserIn] Katrina Hann [verfasserIn] Wenjing Tao [verfasserIn] Shuwary Barlatt [verfasserIn] James Komeh [verfasserIn] Joy Johnson [verfasserIn] Mohamed Sesay [verfasserIn] Mohamed Alex Vandi [verfasserIn] Hannock Tweya [verfasserIn] Collins Timire [verfasserIn] Onome Thomas Abiri [verfasserIn] Fawzi Thomas [verfasserIn] Ahmed Sankoh-Hughes [verfasserIn] Bailah Molleh [verfasserIn] Anna Maruta [verfasserIn] Anthony D. Harries [verfasserIn] |
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E-Artikel |
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Sprache: |
Englisch |
Erschienen: |
2021 |
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Übergeordnetes Werk: |
In: Tropical Medicine and Infectious Disease - MDPI AG, 2017, 6(2021), 2, p 77 |
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Übergeordnetes Werk: |
volume:6 ; year:2021 ; number:2, p 77 |
Links: |
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DOI / URN: |
10.3390/tropicalmed6020077 |
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Katalog-ID: |
DOAJ029887461 |
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520 | |a Monitoring antibiotic consumption is crucial to tackling antimicrobial resistance. However, currently there is no system in Sierra Leone for recording and reporting on antibiotic consumption. We therefore conducted a cross-sectional study to assess national antibiotic consumption expressed as defined daily dose (DDD) per 1000 inhabitants per day using all registered and imported antibiotics (categorized under the subgroup J01 under the anatomical and therapeutic classification (ATC) system) as a proxy. Between 2017–2019, total cumulative consumption of antibiotics was 19 DDD per 1000 inhabitants per day. The vast majority consisted of oral antibiotics (98.4%), while parenteral antibiotics made up 1.6%. According to therapeutic/pharmacological subgroups (ATC level 3), beta-lactam/penicillins, quinolones, and other antibacterials (mainly oral metronidazole) comprised 65% of total consumption. According to WHO Access, Watch, and Reserve (AWaRe), 65% of antibiotics consumed were Access, 31% were Watch, and no Reserve antibiotics were reported. The top ten oral antibiotics represented 97% of total oral antibiotics consumed, with metronidazole (35%) and ciprofloxacin (15%) together constituting half of the total. Of parenteral antibiotics consumed, procaine penicillin (32%) and ceftriaxone (19%) together comprised half of the total. Policy recommendations at global and national levels have been made to improve monitoring of antibiotic consumption and antibiotic stewardship. | ||
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10.3390/tropicalmed6020077 doi (DE-627)DOAJ029887461 (DE-599)DOAJeb0298e6a49a4838ba7532d7a509f48e DE-627 ger DE-627 rakwb eng Joseph Sam Kanu verfasserin aut National Antibiotic Consumption for Human Use in Sierra Leone (2017–2019): A Cross-Sectional Study 2021 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Monitoring antibiotic consumption is crucial to tackling antimicrobial resistance. However, currently there is no system in Sierra Leone for recording and reporting on antibiotic consumption. We therefore conducted a cross-sectional study to assess national antibiotic consumption expressed as defined daily dose (DDD) per 1000 inhabitants per day using all registered and imported antibiotics (categorized under the subgroup J01 under the anatomical and therapeutic classification (ATC) system) as a proxy. Between 2017–2019, total cumulative consumption of antibiotics was 19 DDD per 1000 inhabitants per day. The vast majority consisted of oral antibiotics (98.4%), while parenteral antibiotics made up 1.6%. According to therapeutic/pharmacological subgroups (ATC level 3), beta-lactam/penicillins, quinolones, and other antibacterials (mainly oral metronidazole) comprised 65% of total consumption. According to WHO Access, Watch, and Reserve (AWaRe), 65% of antibiotics consumed were Access, 31% were Watch, and no Reserve antibiotics were reported. The top ten oral antibiotics represented 97% of total oral antibiotics consumed, with metronidazole (35%) and ciprofloxacin (15%) together constituting half of the total. Of parenteral antibiotics consumed, procaine penicillin (32%) and ceftriaxone (19%) together comprised half of the total. Policy recommendations at global and national levels have been made to improve monitoring of antibiotic consumption and antibiotic stewardship. ATC classification AWaRe antibiotic consumption DDD per 1000 inhabitants per day AMR surveillance operational research Medicine R Mohammed Khogali verfasserin aut Katrina Hann verfasserin aut Wenjing Tao verfasserin aut Shuwary Barlatt verfasserin aut James Komeh verfasserin aut Joy Johnson verfasserin aut Mohamed Sesay verfasserin aut Mohamed Alex Vandi verfasserin aut Hannock Tweya verfasserin aut Collins Timire verfasserin aut Onome Thomas Abiri verfasserin aut Fawzi Thomas verfasserin aut Ahmed Sankoh-Hughes verfasserin aut Bailah Molleh verfasserin aut Anna Maruta verfasserin aut Anthony D. Harries verfasserin aut In Tropical Medicine and Infectious Disease MDPI AG, 2017 6(2021), 2, p 77 (DE-627)102556488X 24146366 nnns volume:6 year:2021 number:2, p 77 https://doi.org/10.3390/tropicalmed6020077 kostenfrei https://doaj.org/article/eb0298e6a49a4838ba7532d7a509f48e kostenfrei https://www.mdpi.com/2414-6366/6/2/77 kostenfrei https://doaj.org/toc/2414-6366 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 6 2021 2, p 77 |
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10.3390/tropicalmed6020077 doi (DE-627)DOAJ029887461 (DE-599)DOAJeb0298e6a49a4838ba7532d7a509f48e DE-627 ger DE-627 rakwb eng Joseph Sam Kanu verfasserin aut National Antibiotic Consumption for Human Use in Sierra Leone (2017–2019): A Cross-Sectional Study 2021 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Monitoring antibiotic consumption is crucial to tackling antimicrobial resistance. However, currently there is no system in Sierra Leone for recording and reporting on antibiotic consumption. We therefore conducted a cross-sectional study to assess national antibiotic consumption expressed as defined daily dose (DDD) per 1000 inhabitants per day using all registered and imported antibiotics (categorized under the subgroup J01 under the anatomical and therapeutic classification (ATC) system) as a proxy. Between 2017–2019, total cumulative consumption of antibiotics was 19 DDD per 1000 inhabitants per day. The vast majority consisted of oral antibiotics (98.4%), while parenteral antibiotics made up 1.6%. According to therapeutic/pharmacological subgroups (ATC level 3), beta-lactam/penicillins, quinolones, and other antibacterials (mainly oral metronidazole) comprised 65% of total consumption. According to WHO Access, Watch, and Reserve (AWaRe), 65% of antibiotics consumed were Access, 31% were Watch, and no Reserve antibiotics were reported. The top ten oral antibiotics represented 97% of total oral antibiotics consumed, with metronidazole (35%) and ciprofloxacin (15%) together constituting half of the total. Of parenteral antibiotics consumed, procaine penicillin (32%) and ceftriaxone (19%) together comprised half of the total. Policy recommendations at global and national levels have been made to improve monitoring of antibiotic consumption and antibiotic stewardship. ATC classification AWaRe antibiotic consumption DDD per 1000 inhabitants per day AMR surveillance operational research Medicine R Mohammed Khogali verfasserin aut Katrina Hann verfasserin aut Wenjing Tao verfasserin aut Shuwary Barlatt verfasserin aut James Komeh verfasserin aut Joy Johnson verfasserin aut Mohamed Sesay verfasserin aut Mohamed Alex Vandi verfasserin aut Hannock Tweya verfasserin aut Collins Timire verfasserin aut Onome Thomas Abiri verfasserin aut Fawzi Thomas verfasserin aut Ahmed Sankoh-Hughes verfasserin aut Bailah Molleh verfasserin aut Anna Maruta verfasserin aut Anthony D. Harries verfasserin aut In Tropical Medicine and Infectious Disease MDPI AG, 2017 6(2021), 2, p 77 (DE-627)102556488X 24146366 nnns volume:6 year:2021 number:2, p 77 https://doi.org/10.3390/tropicalmed6020077 kostenfrei https://doaj.org/article/eb0298e6a49a4838ba7532d7a509f48e kostenfrei https://www.mdpi.com/2414-6366/6/2/77 kostenfrei https://doaj.org/toc/2414-6366 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 6 2021 2, p 77 |
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10.3390/tropicalmed6020077 doi (DE-627)DOAJ029887461 (DE-599)DOAJeb0298e6a49a4838ba7532d7a509f48e DE-627 ger DE-627 rakwb eng Joseph Sam Kanu verfasserin aut National Antibiotic Consumption for Human Use in Sierra Leone (2017–2019): A Cross-Sectional Study 2021 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Monitoring antibiotic consumption is crucial to tackling antimicrobial resistance. However, currently there is no system in Sierra Leone for recording and reporting on antibiotic consumption. We therefore conducted a cross-sectional study to assess national antibiotic consumption expressed as defined daily dose (DDD) per 1000 inhabitants per day using all registered and imported antibiotics (categorized under the subgroup J01 under the anatomical and therapeutic classification (ATC) system) as a proxy. Between 2017–2019, total cumulative consumption of antibiotics was 19 DDD per 1000 inhabitants per day. The vast majority consisted of oral antibiotics (98.4%), while parenteral antibiotics made up 1.6%. According to therapeutic/pharmacological subgroups (ATC level 3), beta-lactam/penicillins, quinolones, and other antibacterials (mainly oral metronidazole) comprised 65% of total consumption. According to WHO Access, Watch, and Reserve (AWaRe), 65% of antibiotics consumed were Access, 31% were Watch, and no Reserve antibiotics were reported. The top ten oral antibiotics represented 97% of total oral antibiotics consumed, with metronidazole (35%) and ciprofloxacin (15%) together constituting half of the total. Of parenteral antibiotics consumed, procaine penicillin (32%) and ceftriaxone (19%) together comprised half of the total. Policy recommendations at global and national levels have been made to improve monitoring of antibiotic consumption and antibiotic stewardship. ATC classification AWaRe antibiotic consumption DDD per 1000 inhabitants per day AMR surveillance operational research Medicine R Mohammed Khogali verfasserin aut Katrina Hann verfasserin aut Wenjing Tao verfasserin aut Shuwary Barlatt verfasserin aut James Komeh verfasserin aut Joy Johnson verfasserin aut Mohamed Sesay verfasserin aut Mohamed Alex Vandi verfasserin aut Hannock Tweya verfasserin aut Collins Timire verfasserin aut Onome Thomas Abiri verfasserin aut Fawzi Thomas verfasserin aut Ahmed Sankoh-Hughes verfasserin aut Bailah Molleh verfasserin aut Anna Maruta verfasserin aut Anthony D. Harries verfasserin aut In Tropical Medicine and Infectious Disease MDPI AG, 2017 6(2021), 2, p 77 (DE-627)102556488X 24146366 nnns volume:6 year:2021 number:2, p 77 https://doi.org/10.3390/tropicalmed6020077 kostenfrei https://doaj.org/article/eb0298e6a49a4838ba7532d7a509f48e kostenfrei https://www.mdpi.com/2414-6366/6/2/77 kostenfrei https://doaj.org/toc/2414-6366 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 6 2021 2, p 77 |
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10.3390/tropicalmed6020077 doi (DE-627)DOAJ029887461 (DE-599)DOAJeb0298e6a49a4838ba7532d7a509f48e DE-627 ger DE-627 rakwb eng Joseph Sam Kanu verfasserin aut National Antibiotic Consumption for Human Use in Sierra Leone (2017–2019): A Cross-Sectional Study 2021 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Monitoring antibiotic consumption is crucial to tackling antimicrobial resistance. However, currently there is no system in Sierra Leone for recording and reporting on antibiotic consumption. We therefore conducted a cross-sectional study to assess national antibiotic consumption expressed as defined daily dose (DDD) per 1000 inhabitants per day using all registered and imported antibiotics (categorized under the subgroup J01 under the anatomical and therapeutic classification (ATC) system) as a proxy. Between 2017–2019, total cumulative consumption of antibiotics was 19 DDD per 1000 inhabitants per day. The vast majority consisted of oral antibiotics (98.4%), while parenteral antibiotics made up 1.6%. According to therapeutic/pharmacological subgroups (ATC level 3), beta-lactam/penicillins, quinolones, and other antibacterials (mainly oral metronidazole) comprised 65% of total consumption. According to WHO Access, Watch, and Reserve (AWaRe), 65% of antibiotics consumed were Access, 31% were Watch, and no Reserve antibiotics were reported. The top ten oral antibiotics represented 97% of total oral antibiotics consumed, with metronidazole (35%) and ciprofloxacin (15%) together constituting half of the total. Of parenteral antibiotics consumed, procaine penicillin (32%) and ceftriaxone (19%) together comprised half of the total. Policy recommendations at global and national levels have been made to improve monitoring of antibiotic consumption and antibiotic stewardship. ATC classification AWaRe antibiotic consumption DDD per 1000 inhabitants per day AMR surveillance operational research Medicine R Mohammed Khogali verfasserin aut Katrina Hann verfasserin aut Wenjing Tao verfasserin aut Shuwary Barlatt verfasserin aut James Komeh verfasserin aut Joy Johnson verfasserin aut Mohamed Sesay verfasserin aut Mohamed Alex Vandi verfasserin aut Hannock Tweya verfasserin aut Collins Timire verfasserin aut Onome Thomas Abiri verfasserin aut Fawzi Thomas verfasserin aut Ahmed Sankoh-Hughes verfasserin aut Bailah Molleh verfasserin aut Anna Maruta verfasserin aut Anthony D. Harries verfasserin aut In Tropical Medicine and Infectious Disease MDPI AG, 2017 6(2021), 2, p 77 (DE-627)102556488X 24146366 nnns volume:6 year:2021 number:2, p 77 https://doi.org/10.3390/tropicalmed6020077 kostenfrei https://doaj.org/article/eb0298e6a49a4838ba7532d7a509f48e kostenfrei https://www.mdpi.com/2414-6366/6/2/77 kostenfrei https://doaj.org/toc/2414-6366 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 6 2021 2, p 77 |
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10.3390/tropicalmed6020077 doi (DE-627)DOAJ029887461 (DE-599)DOAJeb0298e6a49a4838ba7532d7a509f48e DE-627 ger DE-627 rakwb eng Joseph Sam Kanu verfasserin aut National Antibiotic Consumption for Human Use in Sierra Leone (2017–2019): A Cross-Sectional Study 2021 Text txt rdacontent Computermedien c rdamedia Online-Ressource cr rdacarrier Monitoring antibiotic consumption is crucial to tackling antimicrobial resistance. However, currently there is no system in Sierra Leone for recording and reporting on antibiotic consumption. We therefore conducted a cross-sectional study to assess national antibiotic consumption expressed as defined daily dose (DDD) per 1000 inhabitants per day using all registered and imported antibiotics (categorized under the subgroup J01 under the anatomical and therapeutic classification (ATC) system) as a proxy. Between 2017–2019, total cumulative consumption of antibiotics was 19 DDD per 1000 inhabitants per day. The vast majority consisted of oral antibiotics (98.4%), while parenteral antibiotics made up 1.6%. According to therapeutic/pharmacological subgroups (ATC level 3), beta-lactam/penicillins, quinolones, and other antibacterials (mainly oral metronidazole) comprised 65% of total consumption. According to WHO Access, Watch, and Reserve (AWaRe), 65% of antibiotics consumed were Access, 31% were Watch, and no Reserve antibiotics were reported. The top ten oral antibiotics represented 97% of total oral antibiotics consumed, with metronidazole (35%) and ciprofloxacin (15%) together constituting half of the total. Of parenteral antibiotics consumed, procaine penicillin (32%) and ceftriaxone (19%) together comprised half of the total. Policy recommendations at global and national levels have been made to improve monitoring of antibiotic consumption and antibiotic stewardship. ATC classification AWaRe antibiotic consumption DDD per 1000 inhabitants per day AMR surveillance operational research Medicine R Mohammed Khogali verfasserin aut Katrina Hann verfasserin aut Wenjing Tao verfasserin aut Shuwary Barlatt verfasserin aut James Komeh verfasserin aut Joy Johnson verfasserin aut Mohamed Sesay verfasserin aut Mohamed Alex Vandi verfasserin aut Hannock Tweya verfasserin aut Collins Timire verfasserin aut Onome Thomas Abiri verfasserin aut Fawzi Thomas verfasserin aut Ahmed Sankoh-Hughes verfasserin aut Bailah Molleh verfasserin aut Anna Maruta verfasserin aut Anthony D. Harries verfasserin aut In Tropical Medicine and Infectious Disease MDPI AG, 2017 6(2021), 2, p 77 (DE-627)102556488X 24146366 nnns volume:6 year:2021 number:2, p 77 https://doi.org/10.3390/tropicalmed6020077 kostenfrei https://doaj.org/article/eb0298e6a49a4838ba7532d7a509f48e kostenfrei https://www.mdpi.com/2414-6366/6/2/77 kostenfrei https://doaj.org/toc/2414-6366 Journal toc kostenfrei GBV_USEFLAG_A SYSFLAG_A GBV_DOAJ GBV_ILN_20 GBV_ILN_22 GBV_ILN_23 GBV_ILN_24 GBV_ILN_31 GBV_ILN_39 GBV_ILN_40 GBV_ILN_60 GBV_ILN_62 GBV_ILN_63 GBV_ILN_65 GBV_ILN_69 GBV_ILN_73 GBV_ILN_74 GBV_ILN_95 GBV_ILN_105 GBV_ILN_110 GBV_ILN_151 GBV_ILN_161 GBV_ILN_170 GBV_ILN_206 GBV_ILN_213 GBV_ILN_230 GBV_ILN_285 GBV_ILN_293 GBV_ILN_602 GBV_ILN_2014 GBV_ILN_4012 GBV_ILN_4037 GBV_ILN_4112 GBV_ILN_4125 GBV_ILN_4126 GBV_ILN_4249 GBV_ILN_4305 GBV_ILN_4306 GBV_ILN_4307 GBV_ILN_4313 GBV_ILN_4322 GBV_ILN_4323 GBV_ILN_4324 GBV_ILN_4325 GBV_ILN_4338 GBV_ILN_4367 GBV_ILN_4700 AR 6 2021 2, p 77 |
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National Antibiotic Consumption for Human Use in Sierra Leone (2017–2019): A Cross-Sectional Study |
abstract |
Monitoring antibiotic consumption is crucial to tackling antimicrobial resistance. However, currently there is no system in Sierra Leone for recording and reporting on antibiotic consumption. We therefore conducted a cross-sectional study to assess national antibiotic consumption expressed as defined daily dose (DDD) per 1000 inhabitants per day using all registered and imported antibiotics (categorized under the subgroup J01 under the anatomical and therapeutic classification (ATC) system) as a proxy. Between 2017–2019, total cumulative consumption of antibiotics was 19 DDD per 1000 inhabitants per day. The vast majority consisted of oral antibiotics (98.4%), while parenteral antibiotics made up 1.6%. According to therapeutic/pharmacological subgroups (ATC level 3), beta-lactam/penicillins, quinolones, and other antibacterials (mainly oral metronidazole) comprised 65% of total consumption. According to WHO Access, Watch, and Reserve (AWaRe), 65% of antibiotics consumed were Access, 31% were Watch, and no Reserve antibiotics were reported. The top ten oral antibiotics represented 97% of total oral antibiotics consumed, with metronidazole (35%) and ciprofloxacin (15%) together constituting half of the total. Of parenteral antibiotics consumed, procaine penicillin (32%) and ceftriaxone (19%) together comprised half of the total. Policy recommendations at global and national levels have been made to improve monitoring of antibiotic consumption and antibiotic stewardship. |
abstractGer |
Monitoring antibiotic consumption is crucial to tackling antimicrobial resistance. However, currently there is no system in Sierra Leone for recording and reporting on antibiotic consumption. We therefore conducted a cross-sectional study to assess national antibiotic consumption expressed as defined daily dose (DDD) per 1000 inhabitants per day using all registered and imported antibiotics (categorized under the subgroup J01 under the anatomical and therapeutic classification (ATC) system) as a proxy. Between 2017–2019, total cumulative consumption of antibiotics was 19 DDD per 1000 inhabitants per day. The vast majority consisted of oral antibiotics (98.4%), while parenteral antibiotics made up 1.6%. According to therapeutic/pharmacological subgroups (ATC level 3), beta-lactam/penicillins, quinolones, and other antibacterials (mainly oral metronidazole) comprised 65% of total consumption. According to WHO Access, Watch, and Reserve (AWaRe), 65% of antibiotics consumed were Access, 31% were Watch, and no Reserve antibiotics were reported. The top ten oral antibiotics represented 97% of total oral antibiotics consumed, with metronidazole (35%) and ciprofloxacin (15%) together constituting half of the total. Of parenteral antibiotics consumed, procaine penicillin (32%) and ceftriaxone (19%) together comprised half of the total. Policy recommendations at global and national levels have been made to improve monitoring of antibiotic consumption and antibiotic stewardship. |
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Monitoring antibiotic consumption is crucial to tackling antimicrobial resistance. However, currently there is no system in Sierra Leone for recording and reporting on antibiotic consumption. We therefore conducted a cross-sectional study to assess national antibiotic consumption expressed as defined daily dose (DDD) per 1000 inhabitants per day using all registered and imported antibiotics (categorized under the subgroup J01 under the anatomical and therapeutic classification (ATC) system) as a proxy. Between 2017–2019, total cumulative consumption of antibiotics was 19 DDD per 1000 inhabitants per day. The vast majority consisted of oral antibiotics (98.4%), while parenteral antibiotics made up 1.6%. According to therapeutic/pharmacological subgroups (ATC level 3), beta-lactam/penicillins, quinolones, and other antibacterials (mainly oral metronidazole) comprised 65% of total consumption. According to WHO Access, Watch, and Reserve (AWaRe), 65% of antibiotics consumed were Access, 31% were Watch, and no Reserve antibiotics were reported. The top ten oral antibiotics represented 97% of total oral antibiotics consumed, with metronidazole (35%) and ciprofloxacin (15%) together constituting half of the total. Of parenteral antibiotics consumed, procaine penicillin (32%) and ceftriaxone (19%) together comprised half of the total. Policy recommendations at global and national levels have been made to improve monitoring of antibiotic consumption and antibiotic stewardship. |
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